未登录 Development of high-affinity nanobodies specific for NaV1.4 and NaV1.5 voltage-gated sodium channel isoforms Srinivasan, Lakshmi; Alzogaray, Vanina; Selvakumar, Dakshnamurthy; Nathan, Sara; Yoder, Jesse B.; Wright, Katharine M.; Klinke, Sebastian; Nwafor, Justin N.; Labanda, Maria S.; Goldbaum, Fernando A.; Schon, Arne; Freire, Ernesto; Tomaselli, Gordon F.; Amzel, L. Mario; Ben-Johny, Manu; Gabelli, Sandra B. 分享 收藏
A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite (vol 24, pg 408, 2018) Kisalu, Neville K.; Idris, Azza H.; Weidle, Connor; Flores-Garcia, Yevel; Flynn, Barbara J.; Sack, Brandon K.; Murphy, Sean; Schon, Arne; Freire, Ernesto; Francica, Joseph R.; Miller, Alex B.; Gregory, Jason; March, Sandra; Liao, Hua-Xin; Haynes, Barton F.; Wiehe, Kevin; Trama, Ashley M.; Saunders, Kevin O.; Gladden, Morgan A.; Monroe, Anthony; Bonsignori, Mattia; Kanekiyo, Masaru; Wheatley, Adam K.; McDermott, Adrian B.; Farney, S. Katie; Chuang, Gwo-Yu; Zhang, Baoshan; Kc, Natasha; Chakravarty, Sumana; Kwong, Peter D.; Sinnis, Photini; Bhatia, Sangeeta N.; Kappe, Stefan H. I.; Sim, B. Kim Lee; Hoffman, Stephen L.; Zavala, Fidel; Pancera, Marie; Seder, Robert A. 分享 收藏
SOSIP Changes Affect Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Conformation and CD4 Engagement SOSIP变化影响人类免疫缺陷病毒1型包膜糖蛋白构象和CD4参与 Alsahafi, Nirmin; Anand, Sai Priya; Castillo-Menendez, Luis; Verly, Myriam Maude; Medjahed, Halima; Prevost, Jeremie; Herschhorn, Alon; Richard, Jonathan; Schon, Arne; Melillo, Bruno; Freire, Ernesto; Smith, Amos B., III; Sodroski, Joseph; Finzia, Andres 分享 收藏
Bioinspired supramolecular engineering of self-assembling immunofibers for high affinity binding of immunoglobulin G Li, Yi; Lock, Lye Lin; Wang, Yuzhu; Ou, Shih-Hao; Stern, David; Schon, Arne; Freire, Ernesto; Xu, Xuankuo; Ghose, Sanchayita; Li, Zheng Jian; Cui, Honggang 分享 收藏
A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite Kisalu, Neville K.; Idris, Azza H.; Weidle, Connor; Flores-Garcia, Yevel; Flynn, Barbara J.; Sack, Brandon K.; Murphy, Sean; Schoen, Arne; Freire, Ernesto; Francica, Joseph R.; Miller, Alex B.; Gregory, Jason; March, Sandra; Liao, Hua-Xin; Haynes, Barton F.; Wiehe, Kevin; Trama, Ashley M.; Saunders, Kevin O.; Gladden, Morgan A.; Monroe, Anthony; Bonsignori, Mattia; Kanekiyo, Masaru; Wheatley, Adam K.; McDermott, Adrian B.; Farney, S. Katie; Chuang, Gwo-Yu; Zhang, Baoshan; Kc, Natasha; Chakravarty, Sumana; Kwong, Peter D.; Sinnis, Photini; Bhatia, Sangeeta N.; Kappe, Stefan H. I.; Sim, B. Kim Lee; Hoffman, Stephen L.; Zavala, Fidel; Pancera, Marie; Seder, Robert A. 分享 收藏
The β20-β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions (vol 8, 2017) Herschhorn, Alon; Gu, Christopher; Moraca, Francesca; Ma, Xiaochu; Farrell, Mark; Smith, Amos B., III; Pancera, Marie; Kwong, Peter D.; Schon, Arne; Freire, Ernesto; Abrams, Cameron; Blanchard, Scott C.; Mothes, Walther; Sodroski, Joseph G. 分享 收藏
The β20-β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions Herschhorn, Alon; Gu, Christopher; Moraca, Francesca; Ma, Xiaochu; Farrell, Mark; Smith, Amos B., III; Pancera, Marie; Kwong, Peter D.; Schon, Arne; Freire, Ernesto; Abrams, Cameron; Blanchard, Scott C.; Mothes, Walther; Sodroski, Joseph G. 分享 收藏
Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529 Pancera, Marie; Lai, Yen-Ting; Bylund, Tatsiana; Druz, Aliaksandr; Narpala, Sandeep; O'Dell, Sijy; Schoen, Arne; Bailer, Robert T.; Chuang, Gwo-Yu; Geng, Hui; Louder, Mark K.; Rawi, Reda; Soumana, Djade I.; Finzi, Andres; Herschhorn, Alon; Madani, Navid; Sodroski, Joseph; Freire, Ernesto; Langley, David R.; Mascola, John R.; McDermott, Adrian B.; Kwong, Peter D. 分享 收藏
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Small-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry Inhibition 小分子CD4-Mimics: 基于结构的HIV-1进入抑制优化 Melillo, Bruno; Liang, Shuaiyi; Park, Jongwoo; Schoen, Arne; Courter, Joel R.; LaLonde, Judith M.; Wendler, Daniel J.; Princiotto, Amy M.; Seaman, Michael S.; Freire, Ernesto; Sodroski, Joseph; Madani, Navid; Hendrickson, Wayne A.; Smith, Amos B., III 分享 收藏
Synthetic, structural mimetics of the β-hairpin flap of HIV-1 protease inhibit enzyme function Chauhan, Jay; Chen, Shen-En; Fenstermacher, Katherine J.; Naser-Tavakolian, Aurash; Reingewertz, Tali; Salmo, Rosene; Lee, Christian; Williams, Emori; Raje, Mithun; Sundberg, Eric; DeStefano, Jeffrey J.; Freire, Ernesto; Fletcher, Steven 分享 收藏
Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo Xu, Qingguo; Ensign, Laura M.; Boylan, Nicholas J.; Schoen, Arne; Gong, Xiaoqun; Yang, Jeh-Chang; Lamb, Nicholas W.; Cai, Shutian; Yu, Tao; Freire, Ernesto; Hanes, Justin 分享 收藏
Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env Do Kwon, Young; Pancera, Marie; Acharya, Priyamvada; Georgiev, Ivelin S.; Crooks, Emma T.; Gorman, Jason; Joyce, M. Gordon; Guttman, Miklos; Ma, Xiaochu; Narpala, Sandeep; Soto, Cinque; Terry, Daniel S.; Yang, Yongping; Zhou, Tongqing; Ahlsen, Goran; Bailer, Robert T.; Chambers, Michael; Chuang, Gwo-Yu; Doria-Rose, Nicole A.; Druz, Aliaksandr; Hallen, Mark A.; Harned, Adam; Kirys, Tatsiana; Louder, Mark K.; O'Dell, Sijy; Ofek, Gilad; Osawa, Keiko; Prabhakaran, Madhu; Sastry, Mallika; Stewart-Jones, Guillaume B. E.; Stuckey, Jonathan; Thomas, Paul V.; Tittley, Tishina; Williams, Constance; Zhang, Baoshan; Zhao, Hong; Zhou, Zhou; Donald, Bruce R.; Lee, Lawrence K.; Zolla-Pazner, Susan; Baxa, Ulrich; Schoen, Arne; Freire, Ernesto; Shapiro, Lawrence; Lee, Kelly K.; Arthos, James; Munro, James B.; Blanchard, Scott C.; Mothes, Walther; Binley, James M.; McDermott, Adrian B.; Mascola, John R.; Kwong, Peter D. 分享 收藏
Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env Georgiev, Ivelin S.; Joyce, M. Gordon; Yang, Yongping; Sastry, Mallika; Zhang, Baoshan; Baxa, Ulrich; Chen, Rita E.; Druz, Aliaksandr; Lees, Christopher R.; Narpala, Sandeep; Schoen, Arne; Van Galen, Joseph; Chuang, Gwo-Yu; Gorman, Jason; Harned, Adam; Pancera, Marie; Stewart-Jones, Guillaume B. E.; Cheng, Cheng; Freire, Ernesto; McDermott, Adrian B.; Mascola, John R.; Kwong, Peter D. 分享 收藏
CD4 mimetics sensitize HIV-1-infected cells to ADCC Richard, Jonathan; Veillette, Maxime; Brassard, Nathalie; Iyerc, Shilpa S.; Roger, Michel; Martin, Loic; Pazgier, Marzena; Schoen, Arne; Freire, Ernesto; Routy, Jean-Pierre; Smith, Amos B., III; Park, Jongwoo; Jones, David M.; Courter, Joel R.; Melillo, Bruno N.; Kaufmann, Daniel E.; Hahn, Beatrice H.; Permar, Sallie R.; Haynes, Barton F.; Madani, Navid; Sodroski, Joseph G.; Finzi, Andres 分享 收藏
CD4-Mimetic Small Molecules Sensitize Human Immunodeficiency Virus to Vaccine-Elicited Antibodies Madani, Navid; Princiotto, Amy M.; Schoen, Arne; LaLonde, Judith; Feng, Yu; Freire, Ernesto; Park, Jongwoo; Courter, Joel R.; Jones, David M.; Robinson, James; Liao, Hua-Xin; Moody, M. Anthony; Permar, Sallie; Haynes, Barton; Smith, Amos B., III; Wyatt, Richard; Sodroski, Joseph 分享 收藏
Structure-Based Design, Synthesis and Validation of CD4-Mimetic Small Molecule Inhibitors of HIV-1 Entry: Conversion of a Viral Entry Agonist to an Antagonist Courter, Joel R.; Madani, Navid; Sodroski, Joseph; Schoen, Arne; Freire, Ernesto; Kwong, Peter D.; Hendrickson, Wayne A.; Chaiken, Irwin M.; LaLonde, Judith M.; Smith, Amos B., III 分享 收藏
Nudel/NudE and Lis1 promote dynein and dynactin interaction in the context of spindle morphogenesis Wang, Shusheng; Ketcham, Stephanie A.; Schoen, Arne; Goodman, Benjamin; Wang, Yueju; Yates, John, III; Freire, Ernesto; Schroer, Trina A.; Zheng, Yixian 分享 收藏
Development of potent dipeptide-type SARS-CoV 3CL protease inhibitors with novel P3 scaffolds: Design, synthesis, biological evaluation, and docking studies Thanigaimalai, Pillaiyar; Konno, Sho; Yamamoto, Takehito; Koiwai, Yuji; Taguchi, Akihiro; Takayama, Kentaro; Yakushiji, Fumika; Akaji, Kenichi; Chen, Shen-En; Naser-Tavakolian, Aurash; Schoen, Arne; Freire, Ernesto; Hayashi, Yoshio 分享 收藏
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