未登录 Modulating immune toxicity in ulcerative colitis using a small molecule RAB27A inhibitor 使用小分子RAB27A抑制剂调节溃疡性结肠炎中的免疫毒性 Meital Ben-David-Naim, PhD; Dan Bijaoui, MsC; Naomi Iluz, PhD; Julian Adams, PhD; Daryl C Drummond, PhD; Yatin Mankan, BA; Christina H Eng, PhD; Jeremy W Herzog, BA; Simon Gray, MD, PhD; Ryan Balfour Sartor, MD; Zvi G Fridlender, MD, MsC; Seth J Salpeter, PhD; Zvi Granot, PhD; null 分享 收藏
In Vitro and In Vivo Activity of a Lipid Nanoparticle System for the In Vivo Generation of CAR T Cells 脂质纳米粒系统在体内外生成CAR T细胞的活性研究 Lemgart, Viktor; Richards, Jennifer; Strauss, Laura; Jiao, Jing; Quido, Brandon; Powers, Laura; Caron, Allison; Shin, Eyoung; Boesch, Austin; Shah, Dharini; Le, Tiffany; Kunden, Rasika; Stewart, Samantha; Nasimi, Fazila; Maiti, Sampa; Ali, Mir; Lihoradova, Olga; Griset, Aaron; Borges, Christopher M.; Kuhlman, William; Lawendowski, Carla; Nielsen, Ulrik; Fantin, Valeria; Drummond, Daryl; Shaffer, Donald; Sawyer, Andrew J. 分享 收藏
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Targeting EphA2 in Bladder Cancer Using a Novel Antibody-Directed Nanotherapeutic Kamoun, Walid; Swindell, Elden; Pien, Christine; Luus, Lia; Cain, Jason; Pham, Minh; Kandela, Irawati; Huang, Zhaohua Richard; Tipparaju, Suresh K.; Koshkaryev, Alexander; Askoxylakis, Vasileios; Kirpotin, Dmitri B.; Bloom, Troy; Mino-Kenudson, Mari; Marks, James D.; Zalutskaya, Alena; Bshara, Wiam; Morrison, Carl; Drummond, Daryl C. 分享 收藏
Synergy between EphA2-ILs-DTXp, a Novel EphA2-Targeted Nanoliposomal Taxane, and PD-1 Inhibitors in Preclinical Tumor Models Kamoun, Walid S.; Dugast, Anne-Sophie; Suchy, James J.; Grabow, Stephanie; Fulton, Ross B.; Sampson, James F.; Luus, Lia; Santiago, Michael; Koshkaryev, Alexander; Sun, Gang; Askoxylakis, Vasileios; Tam, Eric; Huang, Zhaohua Richard; Drummond, Daryl C.; Sawyer, Andrew J. 分享 收藏
Dual targeting of IGF-1R and ErbB3 as a potential therapeutic regimen for ovarian cancer Camblin, Adam J.; Tan, Gege; Curley, Michael D.; Yannatos, Isabel; Iadevaia, Sergio; Rimkunas, Victoria; Mino-Kenudson, Mari; Bloom, Troy; Schoeberl, Birgit; Drummond, Daryl C.; Lugovskoy, Alexey A.; Louis, Chrystal U.; Askoxylakis, Vasileios 分享 收藏
Antibody-mediated targeting of TNFR2 activates CD8+ T cells in mice and promotes antitumor immunity Tam, Eric M.; Fulton, Ross B.; Sampson, James F.; Muda, Marco; Camblin, Adam; Richards, Jennifer; Koshkaryev, Alexander; Tang, Jian; Kurella, Vinodh; Jiao, Yang; Xu, Lihui; Zhang, Kathy; Kohli, Neeraj; Luus, Lia; Hutto, Elizabeth; Kumar, Sandeep; Lulo, James; Paragas, Violette; Wong, Christina; Suchy, James; Grabow, Stephanie; Dugast, Anne-Sophie; Zhang, Hong; Depis, Fabien; Feau, Sonia; Jakubowski, Aniela; Qiao, Wenlian; Craig, Galina; Razlog, Maja; Qiu, James; Zhou, Yu; Marks, James D.; Croft, Michael; Drummond, Daryl C.; Raue, Andreas 分享 收藏
Mechanism of action of a novel agonist TNFR2 antibody that induces co-stimulation of T cells and promotes robust anti-tumor immunity Fulton, Ross B.; Camblin, Adam; Sampson, James F.; Richards, Jennifer; Wong, Christina; Koshkaryev, Alexander; Luus, Lia; Jiao, Yang; Xu, Lihui; Paragas, Violette; Razlog, Maja; Muda, Marco; Tam, Eric M.; Drummond, Daryl C.; Raue, Andreas 分享 收藏
Development of a second-generation TRAIL agonist and predictive biomarker profile for colorectal cancer Ghassemifar, Sara; Hashambhoy-Ramsay, Yasmin; Yuzugullu, Haluk; Utermark, Tamara; Paragas, Violette; Maiwald, Tim; Luus, Lia; Razlog, Maja; Hudson, Hann Ah; Chai, Diane; Schoeberl, Birgit; Reynolds, C. Patrick; Sorger, Peter; Sawyer, Andrew J.; Drummond, Daryl C.; Tam, Eric 分享 收藏
MM-401, a novel anti-TNFR2 antibody that induces T cell co-stimulation, robust anti-tumor activity and immune memory Richards, Jennifer; Wong, Christina; Koshkaryev, Alexander; Fulton, Ross; Camblin, Adam; Sampson, James; Luus, Lia; Suchy, James; Grabow, Stephanie; Kurella, Vinodh; Kumar, Sandeep; Lulo, James; Qiu, James; Jiao, Yang; Xu, Lihui; Paragas, Violette; Razlog, Maja; Muda, Marco; Tam, Eric; Raue, Andreas; Drummond, Daryl 分享 收藏
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Engineering and preclinical activity of MM-201, a best-in-class TRAIL receptor agonist Sawyer, Andrew J.; Ghassemifar, Sara; Wong, Christina; Richards, Jennifer; Grabow, Stephanie; Suchy, James; Koshkaryev, Alexander; Razlog, Maja; Tam, Eric; Drummond, Daryl C. 分享 收藏
Report of the AAPS Guidance Forum on the FDA Draft Guidance for Industry: Drug Products, Including Biological Products, that Contain Nanomaterials de Vlieger, Jon S. B.; Crommelin, Daan J. A.; Tyner, Katherine; Drummond, Daryl C.; Jiang, Wenlei; McNeil, Scott E.; Neervannan, Sesha; Crist, Rachael M.; Shah, Vinod P. 分享 收藏
Antitumour activity and tolerability of an EphA2-targeted nanotherapeutic in multiple mouse models Kamoun, Walid S.; Kirpotin, Dmitri B.; Huang, Zhaohua Richard; Tipparaju, Suresh K.; Noble, Charles O.; Hayes, Mark E.; Luus, Lia; Koshkaryev, Alexander; Kim, Jaeyeon; Olivier, Ken; Kornaga, Tad; Oyama, Shinji; Askoxylakis, Vasileios; Pien, Christine; Kuesters, Geoffrey; Dumont, Nancy; Lugovskoy, Alexey A.; Schihl, Sarah A.; Wilton, John H.; Geddie, Melissa L.; Suchy, James; Grabow, Stephanie; Kohli, Neeraj; Reynolds, C. Patrick; Blaydes, Rachel; Zhou, Yu; Sawyer, Andrew J.; Marks, James D.; Drummond, Daryl C. 分享 收藏
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Targeting EphA2 in bladder cancer using a novel antibody-directed nanotherapeutic Kamoun, Walid; Swindell, Elden; Pien, Christine; Luus, Lia; Cain, Jason; Kandela, Irawati; Huang, Richard; Tipparaju, Suresh; Kirpotin, Dmitri; Bshara, Wiam; Askoxylakis, Vasileios; Morrison, Carl; Drummond, Daryl 分享 收藏
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