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Heterologous mRNA/MVA delivering trimeric-RBD as effective vaccination regimen against SARS-CoV-2: COVARNA Consortium Marcos-Villar, Laura; Perdiguero, Beatriz; Lopez-Bravo, Maria; Zamora, Carmen; Sin, Laura; Alvarez, Enrique; Sorzano, Carlos oscar S.; Sanchez-Cordon, Pedro J.; Casasnovas, Jose M.; Astorgano, David; Garcia-Arriaza, Juan; Anthiya, Shubaash; Borrajo, Mireya L.; Lou, Gustavo; Cuesta, Belen; Franceschini, Lorenzo; Gelpi, Josep L.; Thielemans, Kris; Sistere-Oro, Marta; Meyerhans, Andreas; Garcia, Felipe; Esteban, Ignasi; Lopez-Bigas, Nuria; Plana, Montserrat; Alonso, Maria J.; Esteban, Mariano; Gomez, Carmen Elena 分享 收藏
Assessment of Human SARS CoV-2-Specific T-Cell Responses Elicited In Vitro by New Computationally Designed mRNA Immunogens (COVARNA) Esteban, Ignasi; Pastor-Quinones, Carmen; Usero, Lorena; Aurrecoechea, Elena; Franceschini, Lorenzo; Esprit, Arthur; Gelpi, Josep Lluis; Martinez-Jimenez, Francisco; Lopez-Bigas, Nuria; Breckpot, Karine; Thielemans, Kris; Leal, Lorna; Gomez, Carmen Elena; Sistere-Oro, Marta; Meyerhans, Andreas; Esteban, Mariano; Alonso, Maria Jose; Garcia, Felipe; Plana, Montserrat 分享 收藏
An mRNA mix redirects dendritic cells towards an antiviral program, inducing anticancer cytotoxic stem cell and central memory CD8+ T cells de Mey, Wout; Locy, Hanne; De Ridder, Kirsten; De Schrijver, Phaedra; Autaers, Dorien; Lakdimi, Asma; Esprit, Arthur; Franceschini, Lorenzo; Thielemans, Kris; Verdonck, Magali; Breckpot, Karine 分享 收藏
A synthetic DNA template for fast manufacturing of versatile single epitope mRNA de Mey, Wout; De Schrijver, Phaedra; Autaers, Dorien; Pfitzer, Lena; Fant, Bruno; Locy, Hanne; Esprit, Arthur; Lybaert, Lien; Bogaert, Cedric; Verdonck, Magali; Thielemans, Kris; Breckpot, Karine; Franceschini, Lorenzo 分享 收藏
Trial watch: Dendritic cell (DC)-based immunotherapy for cancer Laureano, Raquel S.; Sprooten, Jenny; Vanmeerbeerk, Isaure; Borras, Daniel M.; Govaerts, Jannes; Naulaerts, Stefan; Berneman, Zwi N.; Beuselinck, Benoit; Bol, Kalijn F.; Borst, Jannie; Coosemans, An; Datsi, Angeliki; Faucikova, Jitka; Kinget, Lisa; Neyns, Bart; Schreibelt, Gerty; Smits, Evelien; Sorg, Rudiger, V; Spisek, Radek; Thielemans, Kris; Tuyaerts, Sandra; De Vleeschouwer, Steven; de Vries, I. Jolanda M.; Xiao, Yanling; Garg, Abhishek D. 分享 收藏
Assessing Tumor-Infiltrating Lymphocytes in Breast Cancer: A Proposal for Combining Immunohistochemistry and Gene Expression Analysis to Refine Scoring Locy, Hanne; Verhulst, Stefaan; Cools, Wilfried; Waelput, Wim; Brock, Stefanie; Cras, Louise; Schiettecatte, Ann; Jonckheere, Jan; van Grunsven, Leo A.; Vanhoeij, Marian; Thielemans, Kris; Breckpot, Karine 分享 收藏
Functional Th1-oriented T follicular helper cells that infiltrate human breast cancer promote effective adaptive immunity Noel, Gregory; Fontsa, Mireille Langouo; Garaud, Soizic; De Silva, Pushpamali; De Wind, Alexandre; Van den Eynden, Gert G.; Salgado, Roberto; Boisson, Anais; Locy, Hanne; Thomas, Noemie; Solinas, Cinzia; Migliori, Edoardo; Naveaux, Celine; Duvillier, Hugues; Lucas, Sophie; Craciun, Ligia; Thielemans, Kris; Larsimont, Denis; Willard-Gallo, Karen 分享 收藏
Single-Domain Antibody Nuclear Imaging Allows Noninvasive Quantification of LAG-3 Expression by Tumor-Infiltrating Leukocytes and Predicts Response of Immune Checkpoint Blockade Lecocq, Quentin; Awad, Robin Maximilian; De Vlaeminck, Yannick; de Mey, Wout; Ertveldt, Thomas; Goyvaerts, Cleo; Raes, Geert; Thielemans, Kris; Keyaerts, Marleen; Devoogdt, Nick; Breckpot, Karine 分享 收藏
Therapeutic Vaccine in Chronically HIV-1-Infected Patients: A Randomized, Double-Blind, Placebo-Controlled Phase IIa Trial with HTI-TriMix de Jong, Wesley; Leal, Lorna; Buyze, Jozefien; Pannus, Pieter; Guardo, Alberto; Salgado, Maria; Mothe, Beatriz; Molto, Jose; Moron-Lopez, Sara; Galvez, Cristina; Florence, Eric; Vanham, Guido; van Gorp, Eric; Brander, Christian; Allard, Sabine; Thielemans, Kris; Martinez-Picado, Javier; Plana, Montserrat; Garcia, Felipe; Gruters, Rob A. 分享 收藏
Single Domain Antibody-Mediated Blockade of Programmed Death-Ligand 1 on Dendritic Cells Enhances CD8 T-cell Activation and Cytokine Production 单域抗体介导的程序性死亡配体1对树突状细胞的阻断可增强CD8 T细胞的活化和细胞因子的产生 Broos, Katrijn; Lecocq, Quentin; De Keersmaecker, Brenda; Raes, Geert; Corthals, Jurgen; Lion, Eva; Thielemans, Kris; Devoogdt, Nick; Keyaerts, Marleen; Breckpot, Karine 分享 收藏
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Phase I clinical trial of an intranodally administered mRNA-based therapeutic vaccine against HIV-1 infection 针对HIV-1感染的基于mRNA的治疗性疫苗的I期临床试验 Leal, Lorna; Guardo, Alberto C.; Moron-Lopez, Sara; Salgado, Maria; Mothe, Beatriz; Heirman, Carlo; Pannus, Pieter; Vanham, Guido; van den Ham, Henk Jan; Gruters, Rob; Andeweg, Arno; Van Meirvenne, Sonja; Pich, Judit; Arnaiz, Joan Albert; Gatell, Josep M.; Brander, Christian; Thielemans, Kris; Martinez-Picado, Javier; Plana, Montserrat; Garcia, Felipe 分享 收藏
Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety 树突状细胞靶向mRNA脂质复合物结合了强大的抗肿瘤T细胞免疫和改善的炎症安全性 Van der Jeught, Kevin; De Koker, Stefaan; Bialkowski, Lukasz; Heirman, Carlo; Joe, Patrick Tjok; Perche, Federico; Maenhout, Sarah; Bevers, Sanne; Broos, Katrijn; Deswarte, Kim; Malard, Virginie; Hammad, Hamida; Baril, Patrick; Benvegnu, Thierry; Jaffres, Paul-Alain; Kooijmans, Sander A. A.; Schiffelers, Raymond; Lienenklaus, Stefan; Midoux, Patrick; Pichon, Chantal; Breckpot, Karine; Thielemans, Kris 分享 收藏
Vegf-A mRNA transfection as a novel approach to improve mouse and human islet graft revascularisation Staels, Willem; Verdonck, Yannick; Heremans, Yves; Leuckx, Gunter; De Groef, Sofie; Heirman, Carlo; de Koning, Eelco; Gysemans, Conny; Thielemans, Kris; Baeyens, Luc; Heimberg, Harry; De Leu, Nico 分享 收藏
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Antibodies Against Immune Checkpoint Molecules Restore Functions of Tumor-Infiltrating T Cells in Hepatocellular Carcinomas 针对免疫检查点分子的抗体可恢复肝细胞癌中肿瘤浸润性T细胞的功能 Zhou, Guoying; Sprengers, Dave; Boor, Patrick P. C.; Doukas, Michail; Schutz, Hannah; Mancham, Shanta; Pedroza-Gonzalez, Alexander; Polak, Wojciech G.; De Jonge, Jeroen; Gaspersz, Marcia; Dong, Haidong; Thielemans, Kris; Pan, Qiuwei; IJzermans, Jan N. M.; Bruno, Marco J.; Kwekkeboom, Jaap 分享 收藏
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