未登录 Small molecule interleukin (IL) 17A/A antagonists and antibodies blocking both IL17A/A and IL17A/F demonstrate equivalent degrees of efficacy in preclinical models of skin and joint inflammation Goedken, Eric R.; Su, Zhi; Lipovsky, Alex; Kannan, Arun; Chu, Katharine L.; Ciura, Samantha; Foley, Sage E.; Frank, Kristine E.; Goess, Christian A.; Gopalakrishnan, Sujatha; Greszler, Stephen N.; Khan, Hasan A.; Leys, Laura J.; King, Jacob J.; Mathieu, Suzanne L.; Panchal, Sanjay C.; Paulsboe, Stephanie; Perham, Matt; Ramos, Ashley L.; Slivka, Peter F.; Srikumaran, Myron; Webster, Matthew P.; Wambeke, Emma L.; Zhu, Haizhong; Scott, Victoria E.; Mcgaraughty, Steve; Honore, Prisca 分享 收藏
分享 收藏
分享 收藏
Cytokine induced 3-D organotypic psoriasis skin model demonstrates distinct roles for NF-κB and JAK pathways in disease pathophysiology Todorovic, Viktor; McDonald, Heath A.; Hoover, Paul; Wetter, Joseph B.; Marinopoulos, Anastasia E.; Woody, Clarissa L.; Miller, Loan; Finkielsztein, Ariel; Dunstan, Robert W.; Paller, Amy S.; Honore, Prisca; Getsios, Spiro; Scott, Victoria E. 分享 收藏
分享 收藏
分享 收藏
Histologic progression of acne inversa/hidradenitis suppurativa: Implications for future investigations and therapeutic intervention Dunstan, Robert W.; Salte, Katherine M.; Todorovic, Viktor; Lowe, Margaret; Wetter, Joseph B.; Harms, Paul W.; Burney, Richard E.; Scott, Victoria E.; Smith, Kathleen M.; Rosenblum, Michael; Gudjonsson, Johann E.; Honore, Prisca 分享 收藏
IL-23 induces regulatory T cell plasticity with implications for inflammatory skin diseases IL-23诱导调节性T细胞可塑性与炎症性皮肤病的关系 Kannan, Arun K.; Su, Zhi; Gauvin, Donna M.; Paulsboe, Stephanie E.; Duggan, Ryan; Lasko, Loren M.; Honore, Prisca; Kort, Michael E.; McGaraughty, Steve P.; Scott, Victoria E.; Gauld, Stephen B. 分享 收藏
Small Molecule IL-36γ Antagonist as a Novel Therapeutic Approach for Plaque Psoriasis Todorovic, Viktor; Su, Zhi; Putman, C. Brent; Kakavas, Stevan J.; Salte, Katherine M.; McDonald, Heath A.; Wetter, Joseph B.; Paulsboe, Stephanie E.; Sun, Qi; Gerstein, Clare E.; Medina, Limary; Sielaff, Bernhard; Sadhukhan, Ramkrishna; Stockmann, Henning; Richardson, Paul L.; Qiu, Wei; Argiriadi, Maria A.; Henry, Rodger F.; Herold, J. Martin; Shotwell, J. Brad; McGaraughty, Steve P.; Honore, Prisca; Gopalakrishnan, Sujatha M.; Sun, Chaohong C.; Scott, Victoria E. 分享 收藏
Small Molecule and Pooled CRISPR Screens Investigating IL17 Signaling Identify BRD2 as a Novel Contributor to Keratinocyte Inflammatory Responses Slivka, Peter F.; Hsieh, Chen-Lin; Lipovsky, Alex; Pratt, Steven D.; Locklear, John; Namovic, Marian T.; McDonald, Heath A.; Wetter, Joseph; Edelmayer, Rebecca; Hu, Min; Murphy, Erin; Domanus, Marc; Lu, Charles; Duggan, Ryan; King, Jacob; Scott, Victoria E.; Donnelly-Roberts, Diana; Slavin, Anthony; Gopalakrishnan, Sujatha; Chung, Namjin; Goedken, Eric R. 分享 收藏
Monocytes/Macrophages play a pathogenic role in IL-23 mediated psoriasis-like skin inflammation Wang, Yibing; Edelmayer, Rebecca; Wetter, Joe; Salte, Katherine; Gauvin, Donna; Leys, Laura; Paulsboe, Stephanie; Su, Zhi; Weinberg, Isaac; Namovic, Marian; Gauld, Stephen B.; Honore, Prisca; Scott, Victoria E.; McGaraughty, Steve 分享 收藏
IL-36 receptor antagonistic antibodies inhibit inflammatory responses in preclinical models of psoriasiform dermatitis Su, Zhi; Paulsboe, Stephanie; Wetter, Joseph; Salte, Katherine; Kannan, Arun; Mathew, Sheeba; Horowitz, Amanda; Gerstein, Clare; Namovic, Marian; Todorovic, Viktor; Seagal, Jane; Edelmayer, Rebecca M.; Viner, Michelle; Rinaldi, Lisa; Zhou, Li; Leys, Laura; Huang, Susan; Wang, Leyu; Sadhukhan, Ramkrishna; Honore, Prisca; McGaraughty, Steve; Scott, Victoria E. 分享 收藏
Quantitative ligand and receptor binding studies reveal the mechanism of interleukin-36 (IL-36) pathway activation Zhou, Li; Todorovic, Viktor; Kakavas, Steve; Sielaff, Bernhard; Medina, Limary; Wang, Leyu; Sadhukhan, Ramkrishna; Stockmann, Henning; Richardson, Paul L.; DiGiammarino, Enrico; Sun, Chaohong; Scott, Victoria 分享 收藏
Cell-Surface Receptor Ligand Interaction Analysis with Homogeneous Time-Resolved FRET and Metabolic Glycan Engineering: Application to Transmembrane and GPI-Anchored Receptors Stockmann, Henning; Todorovic, Viktor; Richardson, Paul L.; Marin, Violeta; Scott, Victoria; Gerstein, Clare; Lake, Marc; Wang, Leyu; Sadhukhan, Ramkrishna; Vasudevan, Anil 分享 收藏
Characterization and comparison of different protocols of oxazolone induced dermatitis in mice McGaraughty, S.; Wetter, J.; Olson, L.; Fossey, S.; Salte, K.; Leys, L.; Huang, S.; Scott, V. E.; Honore, P.; Gauld, S.; Su, Z. 分享 收藏
分享 收藏
Defining a mechanistic link between TRPV3 activity and psoriasis through IL-1α and EGFR signaling pathways Scott, V. E.; Patel, H.; Wetter, J.; Edlmayer, R.; Neelands, T.; Miller, L.; Huang, S.; Gauld, S.; Todorovic, V.; Gomtsian, A.; Dart, M.; Honore, P.; Kym, P. 分享 收藏
分享 收藏
A peripherally acting, selective T-type calcium channel blocker, ABT-639, effectively reduces nociceptive and neuropathic pain in rats (vol 89, pg 536, 2014) Jarvis, Michael F.; Scott, Victoria E.; McGaraughty, Steve; Chu, Katharine L.; Xu, Jun; Niforatos, Wende; Milicic, Ivan; Joshi, Shailen; Zhang, Qingwei; Xia, Zhiren 分享 收藏
Synthesis and SAR of 4-aminocyclopentapyrrolidines as N-type Ca2+ channel blockers with analgesic activity Beebe, Xenia; Darczak, Daria; Henry, Rodger F.; Vortherms, Timothy; Janis, Richard; Namovic, Marian; Donnelly-Roberts, Diana; Kage, Karen L.; Surowy, Carol; Milicic, Ivan; Niforatos, Wende; Swensen, Andrew; Marsh, Kennan C.; Wetter, Jill M.; Franklin, Pamela; Baker, Scott; Zhong, Chengmin; Simler, Gricelda; Gomez, Erica; Boyce-Rustay, Janel M.; Zhu, Chang Z.; Stewart, Andrew O.; Jarvis, Michael F.; Scott, Victoria E. 分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
