Gregory P. Downey - Publications, H-index & Citations

Gregory P. Downey

National Jewish Health

79H指数

340论文数

2.2W被引数

收录论文 124

发表时间

Pro-Inflammatory and Oxidative Responses to Burn Pit Relevant Desert Particulate Matter in Macrophages: A Role for TLR2 Signaling.巨噬细胞对与燃烧坑相关的沙漠颗粒物的促炎和氧化反应：TLR2信号通路的作用。

Free Radical Biology and Medicine

IF8.2

2025-09-23

OAAI

Brian J. Day; Jie Huang; Niccolette Schaunaman; Gregory P. Downey; Hong Wei Chu

Characterizing the role of matrix metalloproteinase-3 (MMP-3) in the pathogenesis of acute respiratory distress syndrome (ARDS)

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-03-01

OAAI

Meneses, Axel; Beke, Keriann; Correll, Kelly; Foster, Daniel; Downey, Gregory; Radisky, Derek; Radisky, Evette

Clustering of phosphatase RPTPα promotes Src signaling and the arthritogenic action of synovial fibroblasts

SCIENCE SIGNALING

IF6.6

2023-07-04

PREAI

Sendo, Sho; Kiosses, William B.; Yang, Shen; Wu, Dennis J.; Lee, Daniel W. K.; Liu, Lin; Aschner, Yael; Vela, Allison J.; Downey, Gregory P.; Santelli, Eugenio; Bottini, Nunzio

Desert particulate matter from Afghanistan increases airway obstruction in human distal lungs exposed to type 2 cytokine IL-13

FRONTIERS IN MEDICINE

IF3

2023-06-28

OAAI

Cervantes, Diana; Schaunaman, Niccolette; Downey, Gregory P.; Chu, Hong Wei; Day, Brian J.

Saracatinib, a Selective Src Kinase Inhibitor, Blocks Fibrotic Responses in Preclinical Models of Pulmonary Fibrosis 选择性Src激酶抑制剂Saracatinib在肺纤维化的临床前模型中阻断纤维化反应

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IF19.4

2022-12-15

OAAI

Ahangari, Farida; Becker, Christine; Foster, Daniel G.; Chioccioli, Maurizio; Nelson, Meghan; Beke, Keriann; Wang, Xing; Justet, Aurelien; Adams, Taylor; Readhead, Benjamin; Meador, Carly; Correll, Kelly; Lili, Loukia N.; Roybal, Helen M.; Rose, Kadi-Ann; Ding, Shuizi; Barnthaler, Thomas; Briones, Natalie; DeIuliis, Giuseppe; Schupp, Jonas C.; Li, Qin; Omote, Norihito; Aschner, Yael; Sharma, Lokesh; Kopf, Katrina W.; Magnusson, Bjorn; Hicks, Ryan; Backmark, Anna; Dela Cruz, Charles S.; Rosas, Ivan; Cousens, Leslie P.; Dudley, Joel T.; Kaminski, Naftali; Downey, Gregory P.

PTPα promotes fibroproliferative responses after acute lung injury

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

IF3.5

2022-07-01

OAAI

Aschner, Yael; Correll, Kelly A.; Beke, Keriann M.; Foster, Daniel G.; Roybal, Helen M.; Nelson, Meghan R.; Meador, Carly L.; Strand, Matthew; Anderson, Kelsey C.; Moore, Camille M.; Reynolds, Paul R.; Kopf, Katrina W.; Burnham, Ellen L.; Downey, Gregory P.

Proteinases in the pathogenesis of lymphangioleiomyomatosis lung disease: nibbling or chewing up the lung

EUROPEAN RESPIRATORY JOURNAL

IF21

2022-04-14

OAAI

Aschner, Yael; Downey, Gregory P.

Engineering of tissue inhibitor of metalloproteinases TIMP-1 for fine discrimination between closely related stromelysins MMP-3 and MMP-10

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-03-01

OAAI

Raeeszadeh-Sarmazdeh, Maryam; Coban, Mathew; Mahajan, Shivansh; Hockla, Alexandra; Sankaran, Banumathi; Downey, Gregory P.; Radisky, Derek C.; Radisky, Evette S.

Role of Particulate Matter from Afghanistan and Iraq in Deployment-Related Lung Disease

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2021-11-22

PREAI

Berman, Reena; Rose, Cecile S.; Downey, Gregory P.; Day, Brian J.; Chu, Hong Wei

501Y.V2 and 501Y.V3 variants of SARS-CoV-2 lose binding to bamlanivimab in vitro

MABS

IF7.3

2021-06-01

OAAI

Liu, Haolin; Wei, Pengcheng; Zhang, Qianqian; Chen, Zhongzhou; Aviszus, Katja; Downing, Walter; Peterson, Shelley; Reynoso, Lyndon; Downey, Gregory P.; Frankel, Stephen K.; Kappler, John; Marrack, Philippa; Zhang, Gongyi

Single-Cell RNA Sequencing Reveals a Unique Monocyte Population in Bronchoalveolar Lavage Cells of Mice Challenged With Afghanistan Particulate Matter and Allergen

TOXICOLOGICAL SCIENCES

IF4.1

2021-05-29

OAAI

Berman, Reena; Min, Elysia; Huang, Jie; Kopf, Katrina; Downey, Gregory P.; Riemondy, Kent; Smith, Harry A.; Rose, Cecile S.; Seibold, Max A.; Chu, Hong Wei; Day, Brian J.

The basis of a more contagious 501Y.V1 variant of SARS-CoV-2

CELL RESEARCH

IF25.9

2021-04-23

OAAI

Liu, Haolin; Zhang, Qianqian; Wei, Pengcheng; Chen, Zhongzhou; Aviszus, Katja; Yang, John; Downing, Walter; Jiang, Chengyu; Liang, Bo; Reynoso, Lyndon; Downey, Gregory P.; Frankel, Stephen K.; Kappler, John; Marrack, Philippa; Zhang, Gongyi

Restarting Respiratory Clinical Research in the Era of the Coronavirus Disease 2019 Pandemic

CHEST

IF8.6

2021-03-01

OAAI

Taylor-Cousar, Jennifer L.; Maier, Lisa; Downey, Gregory P.; Wechsler, Michael E.

Influenza virus infection increases ACE2 expression and shedding in human small airway epithelial cells

EUROPEAN RESPIRATORY JOURNAL

IF21

2021-01-08

OAAI

Schweitzer, Kelly S.; Crue, Taylor; Nall, Jordan M.; Foster, Daniel; Sajuthi, Satria; Correll, Kelly A.; Nakamura, Mari; Everman, Jamie L.; Downey, Gregory P.; Seibold, Max A.; Bridges, James P.; Serban, Karina A.; Chu, Hong Wei; Petrache, Irina

Surrogate Humane Endpoints in Small Animal Models of Acute Lung Injury: A Modified Delphi Consensus Study of Researchers and Laboratory Animal Veterinarians

CRITICAL CARE MEDICINE

IF6

2020-12-16

PREAI

McGinn, Ryan; Fergusson, Dean A.; Stewart, Duncan J.; Kristof, Arnold S.; Barron, Carly C.; Thebaud, Bernard; McIntyre, Lauralyn; Stacey, Dawn; Liepmann, Mark; Dodelet-Devillers, Aurore; Zhang, Haibo; Renlund, Richard; Lilley, Elliot; Downey, Gregory P.; Brown, Earl G.; Cote, Lucie; Dos Santos, Claudia C.; Fox-Robichaud, Alison E.; Hussain, Sabah N. A.; Laffey, John G.; Liu, Mingyao; MacNeil, Jenna; Orlando, Holly; Qureshi, Salman T.; Turner, Patricia, V; Winston, Brent W.; Lalu, Manoj M.

IL-33/ST2 signaling modulates Afghanistan particulate matter induced airway hyperresponsiveness in mice

TOXICOLOGY AND APPLIED PHARMACOLOGY

IF3.4

2020-10-01

OAAI

Berman, Reena; Kopf, Katrina W.; Min, Elysia; Huang, Jie; Downey, Gregory P.; Alam, Rafeul; Chu, Hong Wei; Day, Brian J.

Protein tyrosine phosphatase-α amplifies transforming growth factor-β-dependent profibrotic signaling in lung fibroblasts

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

IF3.5

2020-08-01

OAAI

Aschner, Yael; Nelson, Meghan; Brenner, Matthew; Roybal, Helen; Beke, Keriann; Meador, Carly; Foster, Daniel; Correll, Kelly A.; Reynolds, Paul R.; Anderson, Kelsey; Redente, Elizabeth F.; Matsuda, Jennifer; Riches, David W. H.; Groshong, Steve D.; Pozzi, Ambra; Sap, Jan; Wang, Qin; Rajshankar, Dhaarmini; McCulloch, Christopher A. G.; Zemans, Rachel L.; Downey, Gregory P.

The Leucine-Rich Repeat Region of CARMIL1 Regulates IL-1-Mediated ERK Activation, MMP Expression, and Collagen Degradation

CELL REPORTS

IF6.9

2020-06-01

OAAI

Wang, Qin; Notay, Karambir; Downey, Gregory P.; McCulloch, Christopher A.

Respiratory Health after Military Service in Southwest Asia and Afghanistan An Official American Thoracic Society Workshop Report

ANNALS OF THE AMERICAN THORACIC SOCIETY

IF5.4

2019-08-01

OAAI

Garshick, Eric; Abraham, Joseph H.; Baird, Coleen P.; Ciminera, Paul; Downey, Gregory P.; Falvo, Michael J.; Hart, Jaime E.; Jackson, David A.; Jerrett, Michael; Kuschner, Ware; Helmer, Drew A.; Jones, Kirk D.; Krefft, Silpa D.; Mallon, Timothy; Miller, Robert F.; Morris, Michael J.; Proctor, Susan P.; Redlich, Carrie A.; Rose, Cecile S.; Rull, Rudolph P.; Saers, Johannes; Schneiderman, Aaron, I; Smith, Nicholas L.; Yiallouros, Panayiotis; Blanc, Paul D.

Directed evolution of the metalloproteinase inhibitor TIMP-1 reveals that its N- and C-terminal domains cooperate in matrix metalloproteinase recognition

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-06-01

OAAI

Raeeszadeh-Sarmazdeh, Maryam; Greene, Kerrie A.; Sankaran, Banumathi; Downey, Gregory P.; Radisky, Derek C.; Radisky, Evette S.

研究方向