William W. Bachovchin - Publications, H-index & Citations

William W. Bachovchin

Centenary Institute

45H指数

136论文数

5.7K被引数

收录论文 44

发表时间

A Novel Fibroblast Activation Protein-Based Algorithm to Assess Fibrosis in Metabolic Dysfunction-Associated Steatotic Liver Disease 一种基于成纤维细胞活化蛋白的新型算法，用于评估代谢功能障碍相关脂肪性肝病中的纤维化

Journal of Gastroenterology and Hepatology

IF3.4

2026-02-01

OAAI

Wang, Ziqi, V; Boumelhem, Badwi B.; Pennell, Torsten; Bachovchin, William W.; Lai, Jack Hung-Sen; Poplawski, Sarah E.; Chandraratna, Harsha; Van Der veken, Pieter; Brewer, Kate; Leeming, Diana Julie; Ooi, Geraldine; George, Jacob; Eslam, Mohammed; Adams, Leon A.; Zhang, Hui Emma; McCaughan, Geoffrey W.; Majumdar, Avik; Gorrell, Mark D.

Detection of human PD-1 on T-cells using a fusion protein consisting of an anti-PD-1 single chain variable fragment linked to superfolder GFP

Protein Expression and Purification

IF1.2

2026-01-01

PREAI

Shin, Jong; Sanford, David; Bohm, Alex A.; Bachovchin, William; Bullock, Peter A.

Evolution of Esophageal Adenocarcinoma From Precursor Lesion Stem Cells 食管腺癌从癌前病变干细胞中的演变

Gastroenterology

IF25.1

2025-03-14

OAAI

Wa Xian; Shan Wang; Jingzhong Xie; Yusuke Yamamoto; Melina Khorrami; Yanting Zhang; Raul Caballero Montes; Caycel Desales; Melika Khorrami; Zaal Mory; Ashley Hoffman; Amber Su; Crystal Nguyen; Peter J.A. Davies; Clifford Stephan; Shuang Pan; Wengen Wu; Yuxin Liu; Jeremy Siegelman; Rebecca E. Waters; William A. Ross; Shumei Song; Mark Metersky; David G. Beer; Christopher P. Crum; Alexander J. Stewart; Matthew Vincent; Richard Russell; Robert A. Izard; Khek Yu Ho; Jack Hung-Sen Lai; William W. Bachovchin; Jaffer A. Ajani; Frank D. McKeon

Common vulnerabilities of stem cells along the Barrett's-dysplasia-adenocarcinoma sequence

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Xian, Wa; McKeon, Frank; Crum, Christopher; Ajani, Jaffer; Davies, Peter; Vincent, Matthew; Bachovchin, William; Lai, Hung-Sen; Pan, Shuang; Su, Amber; Hoffman, Ashley; Montes, Raul Caballero; Khorrami, Melina; Khorrami, Melika; Yamamoto, Yusuke

Identification of intrinsic precursors of Barrett's and gastric intestinal metaplasia

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Xian, Wa; McKeon, Frank; Yamamoto, Yusuke; Khorrami, Melika; Khorrami, Melina; Mory, Zaal; Siegelman, Jeremy; Su, Amber; Montes, Raul Caballero; Hoffman, Ashley; Ajani, Jaffer; Crum, Christopher; Bachovchin, William; Wang, Shan; Vincent, Matthew; Nguyen, Crystal

Targeting poly-resistant stem cells in high-grade serous ovarian cancer via synthetic lethal drugs

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Xian, Wa; McKeon, Frank; Crum, Christopher; Ajani, Jaffer; Davies, Peter; Vincent, Matthew; Bachovchin, William; Lai, Hung-Sen; Pan, Shuang; Khorrami, Melina; Khorrami, Melika; Montes, Raul Caballero; Mosaffa, Paria; Hoffman, Ashley; Su, Amber

Preclinical Development of PNT6555, a Boronic Acid-Based, Fibroblast Activation Protein-a (FAP)-Targeted Radiotheranostic for Imaging and Treatment of FAP-Positive Tumors

JOURNAL OF NUCLEAR MEDICINE

IF9.1

2023-11-30

OAAI

Poplawski, Sarah E.; Hallett, Robin M.; Dornan, Mark H.; Novakowski, Kyle E.; Pan, Shuang; Belanger, Anthony P.; Nguyen, Quang-De; Wu, Wengen; Felten, Albert E.; Liu, Yuxin; Ahn, Shin Hye; Hergott, Valerie S.; Jones, Barry; Lai, Jack H.; McCann, Joe A. B.; Bachovchin, William W.

Drug combinations against Barrett's stem cells show efficacy across advanced lesions in esophageal cancer

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Xian, Wa; Lin, Jennifer; Oraei, Mona; McKeon, Frank; Wang, Shan; Ajani, Jaffer; Crum, Christopher; Bachovchin, William; Khorrami, Melina; Su, Amber; Khorrami, Melika; Song, Shumei; Siegelman, Jeremy; Vincent, Matt; Ho, Khek Yu; Yamamoto, Yusuke

Fibroblast activation protein is dispensable for control of glucose homeostasis and body weight in mice

MOLECULAR METABOLISM

IF6.6

2019-01-01

OAAI

Panaro, Brandon L.; Coppage, Andrew L.; Beaudry, Jacqueline L.; Varin, Elodie M.; Kaur, Kirandeep; Lai, Jack H.; Wu, Wengen; Liu, Yuxin; Bachovchin, William W.; Drucker, Daniel J.

DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis

NATURE CHEMICAL BIOLOGY

IF13.7

2016-11-07

240

OAAI

Okondo, Marian C.; Johnson, Darren C.; Sridharan, Ramya; Bin Go, Eun; Chui, Ashley J.; Wang, Mitchell S.; Poplawski, Sarah E.; Wu, Wengen; Liu, Yuxin; Lai, Jack H.; Sanford, David G.; Arciprete, Michael O.; Golub, Todd R.; Bachovchin, William W.; Bachovchin, Daniel A.

Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-04-01

OAAI

Fan, Ming-Hui; Zhu, Qiang; Li, Hui-Hua; Ra, Hyun-Jeong; Majumdar, Sonali; Gulick, Dexter L.; Jerome, Jacob A.; Madsen, Daniel H.; Christofidou-Solomidou, Melpo; Speicher, David W.; Bachovchin, William W.; Feghali-Bostwick, Carol; Pure, Ellen

Inhibition of dipeptidyl peptidase 8/9 impairs preadipocyte differentiation

SCIENTIFIC REPORTS

IF3.9

2015-08-05

OAAI

Han, Ruijun; Wang, Xinying; Bachovchin, William; Zukowska, Zofia; Osborn, John W.

Lower serum fibroblast activation protein shows promise in the exclusion of clinically significant liver fibrosis due to non-alcoholic fatty liver disease in diabetes and obesity

DIABETES RESEARCH AND CLINICAL PRACTICE

IF7.4

2015-06-01

PREAI

Williams, K. H.; de Ribeiro, A. J. Viera; Prakoso, E.; Veillard, A. S.; Shackel, N. A.; Bu, Y.; Brooks, B.; Cavanagh, E.; Raleigh, J.; McLennan, S. V.; McCaughan, G. W.; Bachovchin, W. W.; Keane, F. M.; Zekry, A.; Twigg, S. M.; Gorrell, M. D.

GLP-1(32-36)amide Pentapeptide Increases Basal Energy Expenditure and Inhibits Weight Gain in Obese Mice

DIABETES

IF7.5

2015-04-09

OAAI

Tomas, Eva; Stanojevic, Violeta; McManus, Karen; Khatri, Ashok; Everill, Paul; Bachovchin, William W.; Habener, Joel F.

Cleavage Specificity of Mycobacterium tuberculosis ClpP1P2 Protease and Identification of Novel Peptide Substrates and Boronate Inhibitors with Anti-bacterial Activity

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-04-01

OAAI

Akopian, Tatos; Kandror, Olga; Tsu, Christopher; Lai, Jack H.; Wu, Wengen; Liu, Yuxin; Zhao, Peng; Park, Annie; Wolf, Lisa; Dick, Lawrence R.; Rubin, Eric J.; Bachovchin, William; Goldberg, Alfred L.

Antibody dependent cytotoxicity is enhanced by Ari-4175 through NK cell activation

CANCER RESEARCH

IF16.6

2014-10-01

PREAI

MacFarlane, Alexander; Bagnyukva, Tetyana; Zhang, Jiping; Campbell, Kerry; Jones, Barry; Bachovchin, William; Borghaei, Hossein

A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity

NATURE CHEMICAL BIOLOGY

IF13.7

2014-07-06

OAAI

Bachovchin, Daniel A.; Koblan, Luke W.; Wu, Wengen; Liu, Yuxin; Li, Youhua; Zhao, Peng; Woznica, Iwona; Shu, Ying; Lai, Jack H.; Poplawski, Sarah E.; Kiritsy, Christopher P.; Healey, Sarah E.; DiMare, Matthew; Sanford, David G.; Munford, Robert S.; Bachovchin, William W.; Golub, Todd R.

The high-fat high-fructose hamster as an animal model for niacin's biological activities in humans

METABOLISM-CLINICAL AND EXPERIMENTAL

IF11.9

2013-12-01

PREAI

Connolly, Beth A.; O'Connell, Daniel P.; Lamon-Fava, Stefania; LeBlanc, Daniel F.; Kuang, Yu-Lin; Schaefer, Ernst J.; Coppage, Andrew L.; Benedict, Claude R.; Kiritsy, Christopher P.; Bachovchin, William W.

A General Method for Making Peptide Therapeutics Resistant to Serine Protease Degradation: Application to Dipeptidyl Peptidase IV Substrates

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2013-10-16

PREAI

Heard, Kathryn R.; Wu, Wengen; Li, Youhua; Zhao, Peng; Woznica, Iwona; Lai, Jack H.; Beinborn, Martin; Sanford, David G.; Dimare, Matthew T.; Chiluwal, Amrita K.; Peters, Diane E.; Whicher, Danielle; Sudmeier, James L.; Bachovchin, William W.

A Pan-Inhibitor of DASH Family Enzymes Induces Immune-mediated Regression of Murine Sarcoma and Is a Potent Adjuvant to Dendritic Cell Vaccination and Adoptive T-cell Therapy

JOURNAL OF IMMUNOTHERAPY

IF2.9

2013-10-01

OAAI

Duncan, Brynn B.; Highfill, Steven L.; Qin, Haiying; Bouchkouj, Najat; Larabee, Shannon; Zhao, Peng; Woznica, Iwona; Liu, Yuxin; Li, Youhua; Wu, Wengen; Lai, Jack H.; Jones, Barry; Mackall, Crystal L.; Bachovchin, William W.; Fry, Terry J.

研究方向