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收藏分享 收藏 分享 收藏 Neurodegenerative processes accelerated by protein malnutrition and decelerated by essential amino acids in a tauopathy mouse model在tauopathy小鼠模型中，蛋白质营养不良加速了神经变性过程，而必需氨基酸减慢了神经变性过程
Sato, Hideaki; Takado, Yuhei; Toyoda, Sakiko; Tsukamoto-Yasui, Masako; Minatohara, Keiichiro; Takuwa, Hiroyuki; Urushihata, Takuya; Takahashi, Manami; Shimojo, Masafumi; Ono, Maiko; Maeda, Jun; Orihara, Asumi; Sahara, Naruhiko; Aoki, Ichio; Karakawa, Sachise; Isokawa, Muneki; Kawasaki, Noriko; Kawasaki, Mika; Ueno, Satoko; Kanda, Mayuka; Nishimura, Mai; Suzuki, Katsuya; Mitsui, Akira; Nagao, Kenji; Kitamura, Akihiko; Higuchi, Makoto 分享 收藏 A genetically targeted reporter for PET imaging of deep neuronal circuits in mammalian brainsShimojo, Masafumi; Ono, Maiko; Takuwa, Hiroyuki; Mimura, Koki; Nagai, Yuji; Fujinaga, Masayuki; Kikuchi, Tatsuya; Okada, Maki; Seki, Chie; Tokunaga, Masaki; Maeda, Jun; Takado, Yuhei; Takahashi, Manami; Minamihisamatsu, Takeharu; Zhang, Ming-Rong; Tomita, Yutaka; Suzuki, Norihiro; Maximov, Anton; Suhara, Tetsuya; Minamimoto, Takafumi; Sahara, Naruhiko; Higuchi, Makoto 分享 收藏 Dynamic alterations in the central glutamatergic status following food and glucose intake: in vivo multimodal assessments in humans and animal modelsKubota, Manabu; Kimura, Yasuyuki; Shimojo, Masafumi; Takado, Yuhei; Duarte, Joao M. N.; Takuwa, Hiroyuki; Seki, Chie; Shimada, Hitoshi; Shinotoh, Hitoshi; Takahata, Keisuke; Kitamura, Soichiro; Moriguchi, Sho; Tagai, Kenji; Obata, Takayuki; Nakahara, Jin; Tomita, Yutaka; Tokunaga, Masaki; Maeda, Jun; Kawamura, Kazunori; Zhang, Ming-Rong; Ichise, Masanori; Suhara, Tetsuya; Higuchi, Makoto 分享 收藏 Synthesis and preclinical evaluation of [11C]MTP38 as a novel PET ligand for phosphodiesterase 7 in the brainObokata, Naoyuki; Seki, Chie; Hirata, Takeshi; Maeda, Jun; Ishii, Hideki; Nagai, Yuji; Matsumura, Takehiko; Takakuwa, Misae; Fukuda, Hajime; Minamimoto, Takafumi; Kawamura, Kazunori; Zhang, Ming-Rong; Nakajima, Tatsuo; Saijo, Takeaki; Higuchi, Makoto 分享 收藏 Distinct microglial response against Alzheimer's amyloid and tau pathologies characterized by P2Y12 receptor以P2Y12受体为特征的针对阿尔茨海默氏淀粉样蛋白和tau病理的独特小胶质细胞反应Maeda, Jun; Minamihisamatsu, Takeharu; Shimojo, Masafumi; Zhou, Xiaoyun; Ono, Maiko; Matsuba, Yukio; Ji, Bin; Ishii, Hideki; Ogawa, Masanao; Akatsu, Hiroyasu; Kaneda, Daita; Hashizume, Yoshio; Robinson, John L.; Lee, Virginia M-Y; Saito, Takashi; Saido, Takaomi C.; Trojanowski, John Q.; Zhang, Ming-Rong; Suhara, Tetsuya; Higuchi, Makoto; Sahara, Naruhiko 分享 收藏 分享 收藏 分享 收藏 Design, Synthesis, and Evaluation of (4R)-1-{3-[2-(18F)Fluoro-4-methylpyridin-3-yl]phenyl}-4-[4-(1,3-thiazol-2-ylcarbonyl)piperazin-1-yl]pyrrolidin-2-one ([18F]T-401) as a Novel Positron-Emission Tomography Imaging Agent for Monoacylglycerol LipaseHattori, Yasushi; Aoyama, Kazunobu; Maeda, Jun; Arimura, Naoto; Takahashi, Yasuko; Sasaki, Masako; Fujinaga, Masayuki; Seki, Chie; Nagai, Yuji; Kawamura, Kazunori; Yamasaki, Tomoteru; Zhang, Ming-Rong; Higuchi, Makoto; Koike, Tatsuki 分享 收藏 分享 收藏 In Vivo Visualization of Tau Accumulation, Microglial Activation, and Brain Atrophy in a Mouse Model of Tauopathy rTg4510Ishikawa, Ai; Tokunaga, Masaki; Maeda, Jun; Minamihisamatsu, Takeharu; Shimojo, Masafumi; Takuwa, Hiroyuki; Ono, Maiko; Ni, Ruiqing; Hirano, Shigeki; Kuwabara, Satoshi; Ji, Bin; Zhang, Ming-Rong; Aoki, Ichio; Suhara, Tetsuya; Higuchi, Makoto; Sahara, Naruhiko 分享 收藏 Utilities of tau-pet and TSPO-pet for diagnosing severity of tau-induced disease progression 10.1016/j.jns.2017.08.Ishikawa, A.; Tokunaga, M.; Matsumoto, I.; Minamihisamatsu, T.; Uchida, S.; Maeda, J.; Ji, B.; Takuwa, H.; Shimada, H.; Shinoto, H.; Hirano, S.; Kuwabara, S.; Higuchi, M.; Sahara, N. 分享 收藏 In vivo PET measurements with [11C]PE2I to evaluate fetal mesencephalic transplantations to unilateral 6-OHDA-lesioned ratsInaji, M; Yoshizaki, T; Okauchi, T; Maeda, J; Nagai, Y; Nariai, T; Ohno, K; Ando, K; Okano, H; Obayashi, S; Suhara, T 分享 收藏 Measurement of psychological state changes at low dopamine transporter occupancy following a clinical dose of mazindolKimura, Y.; Maeda, J.; Yamada, M.; Takahata, K.; Yokokawa, K.; Ikoma, Y.; Seki, C.; Ito, H.; Higuchi, M.; Suhara, T. 分享 收藏 Development of TASP0410457 (TASP457), a novel dihydroquinolinone derivative as a PET radioligand for central histamine H3 receptorsKoga, Kazumi; Maeda, Jun; Tokunaga, Masaki; Hanyu, Masayuki; Kawamura, Kazunori; Ohmichi, Mari; Nakamura, Toshio; Nagai, Yuji; Seki, Chie; Kimura, Yasuyuki; Minamimoto, Takafumi; Zhang, Ming-Rong; Fukumura, Toshimitsu; Suhara, Tetsuya; Higuchi, Makoto 分享 收藏 Development of 1-N-11C-Methyl-L- and -D-Tryptophan for pharmacokinetic imaging of the immune checkpoint inhibitor 1-Methyl-TryptophanXie, Lin; Maeda, Jun; Kumata, Katsushi; Yui, Joji; Zhang, Yiding; Hatori, Akiko; Nengaki, Nobuki; Wakizaka, Hidekatsu; Fujinaga, Masayuki; Yamasaki, Tomoteru; Shimoda, Yoko; Higuchi, Makoto; Suhara, Tetsuya; Wang, Feng; Zhang, Ming-Rong 分享 收藏 Development of Novel PET Probes for Central 2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic Acid ReceptorsOi, Norihito; Tokunaga, Masaki; Suzuki, Michiyuki; Nagai, Yuji; Nakatani, Yosuke; Yamamoto, Noboru; Maeda, Jun; Minamimoto, Takafumi; Zhang, Ming-Rong; Suhara, Tetsuya; Higuchi, Makoto 分享 收藏 分享 收藏 
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