Elena Vigorito

university of cambridge

37H指数

73论文数

7.0K被引数

收录论文 38

发表时间

Design and interpretation of eQTL-GWAS colocalisation studies: Lessons from a large-scale evaluation eQTL-GWAS共定位研究的实验设计与结果解读：大规模评估的经验教训

PLoS Genetics

IF3.7

2026-05-08

OAAI

Reales, Guillermo; Pullin, Jeffrey M.; Manipur, Ichcha; Vigorito, Elena; Wallace, Chris

shaPRS: Leveraging shared genetic effects across traits or ancestries improves accuracy of polygenic scores

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2024-06-01

OAAI

Kelemen, Martin; Vigorito, Elena; Fachal, Laura; Anderson, Carl A.; Wallace, Chris

Immunological function in mice lacking the Rac-related GTPase RhoG

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Vigorito, E; Bell, S; Hebeis, BJ; Reynolds, H; McAdam, S; Emson, PC; McKenzie, A; Turner, M

Detection of quantitative trait loci from RNA-seq data with or without genotypes using BaseQTL

NATURE COMPUTATIONAL SCIENCE

IF18.3

2021-06-24

OAAI

Vigorito, Elena; Lin, Wei-Yu; Starr, Colin; Kirk, Paul D. W.; White, Simon R.; Wallace, Chris

EPISPOT: An epigenome-driven approach for detecting and interpreting hotspots in molecular QTL studies

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2021-06-01

OAAI

Ruffieux, Helene; Fairfax, Benjamin P.; Nassiri, Isar; Vigorito, Elena; Wallace, Chris; Richardson, Sylvia; Bottolo, Leonardo

MicroRNA-155 is essential for the optimal proliferation and survival of plasmablast B cells MicroRNA-155对于浆母细胞b细胞的最佳增殖和存活至关重要

LIFE SCIENCE ALLIANCE

IF2.9

2019-05-16

OAAI

Arbore, Giuseppina; Henley, Tom; Biggins, Laura; Andrews, Simon; Vigorito, Elena; Turner, Martin; Leyland, Rebecca

MicroRNA-155 controls affinity-based selection by protecting c-MYC+ B cells from apoptosis

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2015-12-14

OAAI

Nakagawa, Rinako; Leyland, Rebecca; Meyer-Hermann, Michael; Lu, Dong; Turner, Martin; Arbore, Giuseppina; Phan, Tri Giang; Brink, Robert; Vigorito, Elena

Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-05-20

258

OAAI

Curtis, Anne M.; Fagundes, Caio T.; Yang, Guangrui; Palsson-McDermott, Eva M.; Wochal, Paulina; McGettrick, Anne F.; Foley, Niamh H.; Early, James O.; Chen, Lihong; Zhang, Hanrui; Xue, Chenyi; Geiger, Sarah S.; Hokamp, Karsten; Reilly, Muredach P.; Coogan, Andrew N.; Vigorito, Elena; FitzGerald, Garret A.; O'Neill, Luke A. J.

The miR-155-PU.1 axis acts on Pax5 to enable efficient terminal B cell differentiation miR-155-PU.1轴作用于Pax5以实现有效的末端b细胞分化

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2014-10-06

OAAI

Lu, Dong; Nakagawa, Rinako; Lazzaro, Sandra; Staudacher, Philipp; Abreu-Goodger, Cei; Henley, Tom; Boiani, Sara; Leyland, Rebecca; Galloway, Alison; Andrews, Simon; Butcher, Geoffrey; Nutt, Stephen L.; Turner, Martin; Vigorito, Elena

Noncoding RNA and its associated proteins as regulatory elements of the immune system 非编码RNA及其相关蛋白作为免疫系统的调控元件

NATURE IMMUNOLOGY

IF27.6

2014-05-19

169

PREAI

Turner, Martin; Galloway, Alison; Vigorito, Elena

miRNA-155 controls mast cell activation by regulating the PI3Kγ pathway and anaphylaxis in a mouse model 在小鼠模型中，miRNA-155通过调节PI3Kγ 途径和过敏反应来控制肥大细胞的活化

ALLERGY

IF12

2014-04-15

PREAI

Biethahn, K.; Orinska, Z.; Vigorito, E.; Goyeneche-Patino, D. A.; Mirghomizadeh, F.; Foeger, N.; Bulfone-Paus, S.

Macrophage MicroRNA-155 Promotes Cardiac Hypertrophy and Failure

CIRCULATION

IF38.6

2013-09-24

229

OAAI

Heymans, Stephane; Corsten, Maarten F.; Verhesen, Wouter; Carai, Paolo; van Leeuwen, Rick E. W.; Custers, Kevin; Peters, Tim; Hazebroek, Mark; Stoeger, Lauran; Wijnands, Erwin; Janssen, Ben J.; Creemers, Esther E.; Pinto, Yigal M.; Grimm, Dirk; Schuermann, Nina; Vigorito, Elena; Thum, Thomas; Stassen, Frank; Yin, Xiaoke; Mayr, Manuel; de Windt, Leon J.; Lutgens, Esther; Wouters, Kristiaan; de Winther, Menno P. J.; Zacchigna, Serena; Giacca, Mauro; van Bilsen, Marc; Papageorgiou, Anna-Pia; Schroen, Blanche

MiR-210 Is Induced by Oct-2, Regulates B Cells, and Inhibits Autoantibody Production

JOURNAL OF IMMUNOLOGY

IF3.4

2013-09-15

OAAI

Mok, Yingting; Schwierzeck, Vera; Thomas, David C.; Vigorito, Elena; Rayner, Tim F.; Jarvis, Lorna B.; Prosser, Haydn M.; Bradley, Allan; Withers, David R.; Martensson, Inga-Lill; Corcoran, Lynn M.; Blenkiron, Cherie; Miska, Eric A.; Lyons, Paul A.; Smith, Kenneth G. C.

miR-155: an ancient regulator of the immune system

IMMUNOLOGICAL REVIEWS

IF8.3

2013-04-02

277

OAAI

Vigorito, Elena; Kohlhaas, Susan; Lu, Dong; Leyland, Rebecca

Epstein-Barr nuclear antigen 1 induces expression of the cellular microRNA hsa-miR-127 and impairing B-cell differentiation in EBV-infected memory B cells. New insights into the pathogenesis of Burkitt lymphoma Epstein-barr核抗原1诱导EBV感染的记忆b细胞中细胞microRNA hsa-miR-127的表达并损害b细胞分化。伯基特淋巴瘤发病机制的新见解

BLOOD CANCER JOURNAL

IF11.6

2012-08-31

OAAI

Onnis, A.; Navari, M.; Antonicelli, G.; Morettini, F.; Mannucci, S.; De Falco, G.; Vigorito, E.; Leoncini, L.

Chemical structure requirements and cellular targeting of microRNA-122 by peptide nucleic acids anti-miRs

NUCLEIC ACIDS RESEARCH

IF13.1

2011-11-08

119

OAAI

Torres, Adrian G.; Fabani, Martin M.; Vigorito, Elena; Williams, Donna; Al-Obaidi, Naowras; Wojciechowski, Filip; Hudson, Robert H. E.; Seitz, Oliver; Gait, Michael J.

MicroRNA fate upon targeting with anti-miRNA oligonucleotides as revealed by an improved Northern-blot-based method for miRNA detection

RNA

IF5

2011-03-25

OAAI

Torres, Adrian G.; Fabani, Martin M.; Vigorito, Elena; Gait, Michael J.

Efficient inhibition of miR-155 function in vivo by peptide nucleic acids

NUCLEIC ACIDS RESEARCH

IF13.1

2010-03-11

200

OAAI

Fabani, Martin M.; Abreu-Goodger, Cei; Williams, Donna; Lyons, Paul A.; Torres, Adrian G.; Smith, Kenneth G. C.; Enright, Anton J.; Gait, Michael J.; Vigorito, Elena

HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species

NATURE IMMUNOLOGY

IF27.6

2010-02-07

210

OAAI

Capasso, Melania; Bhamrah, Mandeep K.; Henley, Tom; Boyd, Robert S.; Langlais, Claudia; Cain, Kelvin; Dinsdale, David; Pulford, Karen; Khan, Mahmood; Musset, Boris; Cherny, Vladimir V.; Morgan, Deri; Gascoyne, Randy D.; Vigorito, Elena; DeCoursey, Thomas E.; MacLennan, Ian C. M.; Dyer, Martin J. S.

Vav GEFs regulate macrophage morphology and adhesion-induced Rac and Rho activation

EXPERIMENTAL CELL RESEARCH

IF3.5

2009-11-01

PREAI

Bhavsar, Parag J.; Vigorito, Elena; Turner, Martin; Ridley, Anne J.

研究方向