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Developmental mosaicism underlying EGFR-mutant lung cancer presenting with multiple primary tumors 表现为多原发肿瘤的EGFR突变肺癌的发育镶嵌 Burr, Risa; Leshchiner, Ignaty; Costantino, Christina L.; Blohmer, Martin; Sundaresan, Tilak; Cha, Justin; Seeger, Karsen; Guay, Sara; Danysh, Brian P.; Gore, Ira; Jacobs, Raquel A.; Slowik, Kara; Utro, Filippo; Rhrissorrakrai, Kahn; Levovitz, Chaya; Barth, Jaimie L.; Dubash, Taronish; Chirn, Brian; Parida, Laxmi; Sequist, Lecia V.; Lennerz, Jochen K.; Mino-Kenudson, Mari; Maheswaran, Shyamala; Naxerova, Kamila; Getz, Gad; Haber, Daniel A. 分享 收藏
Response-guided neoadjuvant sacituzumab govitecan for localized triple-negative breast cancer: results from the NeoSTAR trial sacituzumab govitecan治疗局部三阴性乳腺癌的新辅助治疗: 来自NeoSTAR试验的结果 Spring, L. M.; Tolaney, S. M.; Fell, G.; Bossuyt, V.; Abelman, R. O.; Wu, B.; Maheswaran, S.; Trippa, L.; Comander, A.; Mulvey, T.; McLaughlin, S.; Ryan, P.; Ryan, L.; Abraham, E.; Rosenstock, A.; Garrido-Castro, A. C.; Lynce, F.; Moy, B.; Isakoff, S. J.; Tung, N.; Mittendorf, E. A.; Ellisen, L. W.; Bardia, A. 分享 收藏
Modeling the novel SERD elacestrant in cultured fulvestrant-refractory HR-positive breast circulating tumor cells Dubash, Taronish D.; Bardia, Aditya; Chirn, Brian; Reeves, Brittany A.; LiCausi, Joseph A.; Burr, Risa; Wittner, Ben S.; Rai, Sumit; Patel, Hitisha; Bihani, Teeru; Arlt, Heike; Bidard, Francois-Clement; Kaklamani, Virginia G.; Aftimos, Philippe; Cortes, Javier; Scartoni, Simona; Fiascarelli, Alessio; Binaschi, Monica; Habboubi, Nassir; Iafrate, A. John; Toner, Mehmet; Haber, Daniel A.; Maheswaran, Shyamala 分享 收藏
Efficacy of novel oral SERD elacestrant in fulvestrant-refractory hormone receptor-positive (HR plus ) breast cancer: a translational investigation Dubash, Taronish D.; Bardia, Aditya; Chirn, Brian; Reeves, Brittany A.; LiCausi, Joseph A.; Burr, Risa; Wittner, Ben S.; Rai, Sumit; Patel, Hitisha; Bihani, Teeru; Arlt, Heike; Bidard, Francois-Clement; Kaklamani, Virginia G.; Aftimos, Philippe; Cortes, Javier; Scartoni, Simona; Binaschi, Monica; Habboubi, Nassir; Iafrate, A. John; Toner, Mehmet; Haber, Daniel A.; Maheswaran, Shyamala 分享 收藏
Mechanisms of genetic predisposition to multifocal lung cancer 多灶性肺癌的遗传易感性机制 Burr, Risa; Leshchiner, Ignaty; Costantino, Christina L.; Blohmer, Martin; Sundaresan, Tilak; Cha, Justin; Seeger, Karsen; Guay, Sara; Danysh, Brian P.; Gore, Ira; Jacobs, Raquel A.; Slowik, Kara; Utro, Filippo; Rhrissorrakrai, Kahn; Levovitz, Chaya; Barth, Jaimie L.; Dubash, Taronish; Chirn, Brian; Parida, Laxmi; Sequist, Lecia V.; Mino-Kenudson, Mari; Naxerova, Kamila; Maheswaran, Shyamala; Getz, Gad; Haber, Daniel A. 分享 收藏
Downregulation of KEAP1 in melanoma promotes resistance to immune checkpoint blockade Fox, Douglas B.; Ebright, Richard Y.; Hong, Xin; Russell, Hunter C.; Guo, Hongshan; LaSalle, Thomas J.; Wittner, Ben S.; Poux, Nicolas; Vuille, Joanna A.; Toner, Mehmet; Hacohen, Nir; Boland, Genevieve M.; Sen, Debattama R.; Sullivan, Ryan J.; Maheswaran, Shyamala; Haber, Daniel A. 分享 收藏
TGF β in the microenvironment induces a physiologically occurring immune-suppressive senescent state Matsuda, Satoru; Revandkar, Ajinkya; Dubash, Taronish D.; Ravi, Arvind; Wittner, Ben S.; Lin, Maoxuan; Morris, Robert; Burr, Risa; Guo, Hongshan; Seeger, Karsen; Szabolcs, Annamaria; Che, Dante; Nieman, Linda; Getz, Gad A.; Ting, David T.; Lawrence, Michael S.; Gainor, Justin; Haber, Daniel A.; Maheswaran, Shyamala 分享 收藏
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Targeting breast and pancreatic cancer metastasis using a dual-cadherin antibody 使用双钙粘蛋白抗体靶向乳腺癌和胰腺癌转移 Micalizzi, Douglas S.; Che, Dante; Nicholson, Benjamin T.; Edd, Jon F.; Desai, Niyati; Lang, Evan R.; Toner, Mehmet; Maheswaran, Shyamala; Ting, David T.; Haber, Daniel A. 分享 收藏
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Association between co-existing genomic alterations and abemaciclib benefit in patients with metastatic hormone receptor-positive breast cancer with ESR1 mutations following disease progression on prior endocrine therapy plus palbociclib or ribociclib Brett, Jamie O.; Dubash, Taronish D.; Niemierko, Andrzej; Mariotti, Veronica; Kim, Leslie S. L.; Xi, Jing; Pandey, Apurva; Dunne, Siobhan; Nasrazadani, Azadeh; Lloyd, Maxwell R.; Spring, Laura M.; Micalizzi, Douglas; Onozato, Maristela; Che, Dante; Brufsky, Adam; Kalinsky, Kevin M.; Ma, Cynthia X.; O'Shaughnessy, Joyce; Han, Hyo S.; Iafrate, A. John; Maheswaran, Shyamala; Haber, Daniel A.; Bardia, Aditya; Wander, Seth A. 分享 收藏
AKT inhibition in combination with endocrine therapy and a CDK4/6 inhibitor (CDK4/6i) in patients with hormone receptor positive (HR+)/HER2 negative metastatic breast cancer (MBC) and prior CDK4/6i exposure: A translational investigation Wander, Seth A.; Micalizzi, Douglas S.; Dubash, Taronish; Juric, Dejan; Spring, Laura M.; Vidula, Neelima; Keenan, Jennifer; Beeler, Maureen; Viscosi, Elene; Che, Dante; Fisher, Elizabeth L.; Hepp, Rachel A.; Moy, Beverly; Isakoff, Steven J.; Ellisen, Leif W.; Supko, Jeffrey G.; Maheswaran, Shyamala; Haber, Daniel A.; Bardia, Aditya 分享 收藏
NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer Guo, Hongsha; Golczer, Gabriel; Wittner, Ben S.; Langenbucher, Adam; Zachariah, Marcus; Dubash, Taronish D.; Hong, Xin; Comaills, Valentine; Burr, Risa; Ebright, Richard Y.; Horwitz, Elad; Vuille, Joanna A.; Hajizadeh, Soroush; Wiley, Devon F.; Reeves, Brittany A.; Zhang, Jia-min; Niederhoffer, Kira L.; Lu, Chenyue; Wesley, Benjamin; Ho, Uyen; Nieman, Linda T.; Toner, Mehmet; Vasudevan, Shobha; Zou, Lee; Mostoslavsky, Raul; Maheswaran, Shyamala; Lawrence, Michael S.; Harber, Daniel A. 分享 收藏
Evaluation of endocrine resistance using ESR1 genotyping of circulating tumor cells and plasma DNA Sundaresan, Tilak K.; Dubash, Taronish D.; Zheng, Zongli; Bardia, Aditya; Wittner, Ben S.; Aceto, Nicola; Silva, Erin J.; Fox, Douglas B.; Liebers, Matthew; Kapur, Ravi; Iafrate, John; Toner, Mehmet; Maheswaran, Shyamala; Haber, Daniel A. 分享 收藏
The Lipogenic Regulator SREBP2 Induces Transferrin in Circulating Melanoma Cells and Suppresses Ferroptosis 脂肪生成调节剂SREBP2诱导循环黑素瘤细胞中的转铁蛋白并抑制铁死亡 Hong, Xin; Roh, Whijae; Sullivan, Ryan J.; Wong, Keith H. K.; Wittner, Ben S.; Guo, Hongshan; Dubash, Taronish D.; Sade-Feldman, Moshe; Wesley, Benjamin; Horwitz, Elad; Boland, Genevieve M.; Marvin, Dieuwke L.; Bonesteel, Todd; Lu, Chenyue; Aguet, Francois; Burr, Risa; Freeman, Samuel S.; Parida, Laxmi; Calhoun, Katherine; Jewett, Michelle K.; Nieman, Linda T.; Hacohen, Nir; Naar, Anders M.; Ting, David T.; Toner, Mehmet; Stott, Shannon L.; Getz, Gad; Maheswaran, Shyamala; Haber, Daniel A. 分享 收藏
HIF1A signaling selectively supports proliferation of breast cancer in the brain Ebright, Richard Y.; Zachariah, Marcus A.; Micalizzi, Douglas S.; Wittner, Ben S.; Niederhoffer, Kira L.; Nieman, Linda T.; Chirn, Brian; Wiley, Devon F.; Wesley, Benjamin; Shaw, Brian; Nieblas-Bedolla, Edwin; Atlas, Lian; Szabolcs, Annamaria; Iafrate, Anthony J.; Toner, Mehmet; Ting, David T.; Brastianos, Priscilla K.; Haber, Daniel A.; Maheswaran, Shyamala 分享 收藏
Ultrahigh-throughput magnetic sorting of large blood volumes for epitope-agnostic isolation of circulating tumor cells Mishra, Avanish; Dubash, Taronish D.; Edd, Jon F.; Jewett, Michelle K.; Garre, Suhaas G.; Karabacak, Nezihi Murat; Rabe, Daniel C.; Mutlu, Baris R.; Walsh, John R.; Kapur, Ravi; Stott, Shannon L.; Maheswaran, Shyamala; Haber, Daniel A.; Toner, Mehmet 分享 收藏
Pancreatic circulating tumor cell profiling identifies LIN28B as a metastasis driver and drug target Franses, Joseph W.; Philipp, Julia; Missios, Pavlos; Bhan, Irun; Liu, Ann; Yashaswini, Chittampalli; Tai, Eric; Zhu, Huili; Ligorio, Matteo; Nicholson, Benjamin; Tassoni, Elizabeth M.; Desai, Niyati; Kulkarni, Anupriya S.; Szabolcs, Annamaria; Hong, Theodore S.; Liss, Andrew S.; Fernandez-del Castillo, Carlos; Ryan, David P.; Maheswaran, Shyamala; Haber, Daniel A.; Daley, George Q.; Ting, David T. 分享 收藏
Elacestrant (RAD1901) inhibits growth of ex vivo cultured circulating tumor cells derived from hormone receptor-positive metastatic breast cancer (mBC) patients including those harboring ESR1 mutations Dubash, Taronish Dorab; Bardia, Aditya; Reeves, Brittany A.; Chirn, Brian; Szabolcs, Annamaria; Wittner, Ben S.; Iafrate, John; Ting, David; Patel, Hitisha K.; Bihani, Teeru; Toner, Mehmet; Haber, Daniel A.; Maheswaran, Shyamala 分享 收藏
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