未登录 High throughput screening strategies in the development of logic gated cell therapies Wang, Li; Panagiotopoulou, Sofia Kyriazopoulou; Harari-Steinfeld, Rona; De Silva, Dasmanthie; Tan, Michelle; Lim, Laura; Boroughs, Angela; Sue, Cate; Chen, Jon; Thomas, Jamie; Chua, Mary; Yashin, Ed; Shieh, Christine; Fong, Ryan; Xu, Sophie; Zheng, Grace; Galvin, Brendan; Cooper, Aaron; Mikkelsen, Tarjei; Haining, Nicholas 分享 收藏
Integrated pseudotime analysis of human pre-implantation embryo single-cell transcriptomes reveals the dynamics of lineage specification 人类植入前胚胎单细胞转录组的综合假时间分析揭示了谱系规范的动态 Meistermann, Dimitri; Bruneau, Alexandre; Loubersac, Sophie; Reignier, Arnaud; Firmin, Julie; Francois-Campion, Valentin; Kilens, Stephanie; Lelievre, Yohann; Lammers, Jenna; Feyeux, Magalie; Hulin, Phillipe; Nedellec, Steven; Bretin, Betty; Castel, Gael; Allegre, Nicolas; Covin, Simon; Bihouee, Audrey; Soumillon, Magali; Mikkelsen, Tarjei; Barriere, Paul; Chazaud, Claire; Chappell, Joel; Pasque, Vincent; Bourdon, Jeremie; Freour, Thomas; David, Laurent 分享 收藏
Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing 通过直接引导RNA捕获和靶向测序进行组合单细胞CRISPR筛选 Replogle, Joseph M.; Norman, Thomas M.; Xu, Albert; Hussmann, Jeffrey A.; Chen, Jin; Cogan, J. Zachery; Meer, Elliott J.; Terry, Jessica M.; Riordan, Daniel P.; Srinivas, Niranjan; Fiddes, Ian T.; Arthur, Joseph G.; Alvarado, Luigi J.; Pfeiffer, Katherine A.; Mikkelsen, Tarjei S.; Weissman, Jonathan S.; Adamson, Britt 分享 收藏
Loss of DNA methyltransferase activity in primed human ES cells triggers increased cell-cell variability and transcriptional repression Tsankov, Alexander M.; Wadsworth, Marc H., II; Akopian, Veronika; Charlton, Jocelyn; Allon, Samuel J.; Arczewska, Aleksandra; Mead, Benjamin E.; Drake, Riley S.; Smith, Zachary D.; Mikkelsen, Tarjei S.; Shalek, Alex K.; Meissner, Alexander 分享 收藏
Identification of Functional Variants in the FAM13A Chronic Obstructive Pulmonary Disease Genome-Wide Association Study Locus by Massively Parallel Reporter Assays 通过大规模平行报告分析鉴定FAM13A慢性阻塞性肺疾病全基因组关联研究基因座中的功能变异 Castaldi, Peter J.; Guo, Feng; Qiao, Dandi; Du, Fei; Naing, Zun Zar Chi; Li, Yan; Pham, Betty; Mikkelsen, Tarjei S.; Cho, Michael H.; Silverman, Edwin K.; Zhou, Xiaobo 分享 收藏
Aligning Single-Cell Developmental and Reprogramming Trajectories Identifies Molecular Determinants of Myogenic Reprogramming Outcome Cacchiarelli, Davide; Qiu, Xiaojie; Srivatsan, Sanjay; Manfredi, Anna; Ziller, Michael; Overbey, Eliah; Grimaldi, Antonio; Grimsby, Jonna; Pokharel, Prapti; Livak, Kenneth J.; Li, Shuqiang; Meissner, Alexander; Mikkelsen, Tarjei S.; Rinn, John L.; Trapnell, Cole 分享 收藏
Analyzing infiltrating B cell populations in the tumor microenvironment using single cell transcriptomics Taylor, Sarah E.; Boutet, Stephane; Giangarra, Valeria; Zheng, Grace X.; Barrio, Alvaro M.; Montesclaros, Luz; Lee, Josephine; Marrs, Samuel; Wu, Kevin J.; Ryvkin, Paul; Mikkelsen, Tarjei; Church, Deanna M. 分享 收藏
Identifying genetic variation and cellular heterogeneity with a comprehensive cancer analysis toolkit Garcia, Sarah; Bharadwaj, Rajiv; Boutet, Stephane; Catalanotti, Claudia; Giangerra, Valeria; Lee, Josephine; Terry, Jessica; Williams, Stephen; Zheng, Grace X.; Mikkelsen, Tarjei; Schnall-Levin, Michael; Hindson, Ben; Church, Deanna M. 分享 收藏
Parallel derivation of isogenic human primed and naive induced pluripotent stem cells Kilens, Stephanie; Meistermann, Dimitri; Moreno, Diego; Chariau, Caroline; Gaignerie, Anne; Reignier, Arnaud; Lelievre, Yohann; Casanova, Miguel; Vallot, Celine; Nedellec, Steven; Flippe, Lea; Firmin, Julie; Song, Juan; Charpentier, Eric; Lammers, Jenna; Donnart, Audrey; Marec, Nadege; Deb, Wallid; Bihouee, Audrey; Le Caignec, Cedric; Pecqueur, Claire; Redon, Richard; Barriere, Paul; Bourdon, Jeremie; Pasque, Vincent; Soumillon, Magali; Mikkelsen, Tarjei S.; Rougeulle, Claire; Freour, Thomas; David, Laurent 分享 收藏
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Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity Yan, Kelley S.; Gevaert, Olivier; Zheng, Grace X. Y.; Anchang, Benedict; Probert, Christopher S.; Larkin, Kathryn A.; Davies, Paige S.; Cheng, Zhuan-fen; Kaddis, John S.; Han, Arnold; Roelf, Kelly; Calderon, Ruben I.; Cynn, Esther; Hu, Xiaoyi; Mandleywala, Komal; Wilhelmy, Julie; Grimes, Sue M.; Corney, David C.; Boutet, Stephane C.; Terry, Jessica M.; Belgrader, Phillip; Ziraldo, Solongo B.; Mikkelsen, Tarjei S.; Wang, Fengchao; von Furstenberg, Richard J.; Smith, Nicholas R.; Chandrakesan, Parthasarathy; May, Randal; Chrissy, Mary Ann S.; Jain, Rajan; Cartwright, Christine A.; Niland, Joyce C.; Hong, Young-Kwon; Carrington, Jill; Breault, David T.; Epstein, Jonathan; Houchen, Courtney W.; Lynch, John P.; Martin, Martin G.; Plevritis, Sylvia K.; Curtis, Christina; Ji, Hanlee P.; Li, Linheng; Henning, Susan J.; Wong, Melissa H.; Kuo, Calvin J. 分享 收藏
Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci Pashos, Evanthia E.; Park, Yoson; Wang, Xiao; Raghavan, Avanthi; Yang, Wenli; Abbey, Deepti; Peters, Derek T.; Arbelaez, Juan; Hernandez, Mayda; Kuperwasser, Nicolas; Li, Wenjun; Lian, Zhaorui; Liu, Ying; Lv, Wenjian; Lytle-Gabbin, Stacey L.; Marchadier, Dawn H.; Rogov, Peter; Shi, Jianting; Slovik, Katherine J.; Stylianou, Ioannis M.; Wang, Li; Yan, Ruilan; Zhang, Xiaolan; Kathiresan, Sekar; Duncan, Stephen A.; Mikkelsen, Tarjei S.; Morrisey, Edward E.; Rader, Daniel J.; Brown, Christopher D.; Musunuru, Kiran 分享 收藏
Systematic dissection of genomic features determining transcription factor binding and enhancer function 确定转录因子结合和增强子功能的基因组特征的系统解剖 Grossman, Sharon R.; Zhang, Xiaolan; Wang, Li; Engreitz, Jesse; Melnikov, Alexandre; Rogov, Peter; Tewhey, Ryan; Isakova, Alina; Deplancke, Bart; Bernstein, Bradley E.; Mikkelsen, Tarjei S.; Lander, Eric S. 分享 收藏
Registry in a tube: multiplexed pools of retrievable parts for genetic design space exploration (vol 45, pg 1567, 2017) Woodruff, Lauren B. A.; Gorochowski, Thomas E.; Roehner, Nicholas; Mikkelsen, Tarjei S.; Densmore, Douglas; Gordon, D. Benjamin; Nicol, Robert; Voigt, Christopher A. 分享 收藏
Massively parallel digital transcriptional profiling of single cells 单细胞的大规模并行数字转录谱分析 Zheng, Grace X. Y.; Terry, Jessica M.; Belgrader, Phillip; Ryvkin, Paul; Bent, Zachary W.; Wilson, Ryan; Ziraldo, Solongo B.; Wheeler, Tobias D.; McDermott, Geoff P.; Zhu, Junjie; Gregory, Mark T.; Shuga, Joe; Montesclaros, Luz; Underwood, Jason G.; Masquelier, Donald A.; Nishimura, Stefanie Y.; Schnall-Levin, Michael; Wyatt, Paul W.; Hindson, Christopher M.; Bharadwaj, Rajiv; Wong, Alexander; Ness, Kevin D.; Beppu, Lan W.; Deeg, H. Joachim; McFarland, Christopher; Loeb, Keith R.; Valente, William J.; Ericson, Nolan G.; Stevens, Emily A.; Radich, Jerald P.; Mikkelsen, Tarjei S.; Hindson, Benjamin J.; Bielas, Jason H. 分享 收藏
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Prospective functional classification of all possible missense variants in PPARG Majithia, Amit R.; Tsuda, Ben; Agostini, Maura; Gnanapradeepan, Keerthana; Rice, Robert; Peloso, Gina; Patel, Kashyap A.; Zhang, Xiaolan; Broekema, Marjoleine F.; Patterson, Nick; Duby, Marc; Sharpe, Ted; Kalkhoven, Eric; Rosen, Evan D.; Barroso, Ines; Ellard, Sian; Kathiresan, Sekar; O'Rahilly, Stephen; Chatterjee, Krishna; Florez, Jose C.; Mikkelsen, Tarjei; Savage, David B.; Altshuler, David 分享 收藏
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Phenotypic Characterization of a Comprehensive Set of MAPK1/ERK2 Missense Mutants Brenan, Lisa; Andreev, Aleksandr; Cohen, Ofir; Pantel, Sasha; Kamburov, Atanas; Cacchiarelli, Davide; Persky, Nicole S.; Zhu, Cong; Bagul, Mukta; Goetz, Eva M.; Burgin, Alex B.; Garraway, Levi A.; Getz, Gad; Mikkelsen, Tarjei S.; Piccioni, Federica; Root, David E.; Johannessen, Cory M. 分享 收藏
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