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Meindert Danhof

Leiden University

70H指数
631论文数
1.9W被引数
收录论文 217
发表时间
TRIBUTE In memoriam Lambertus (Bert) A. Peletier 29 March 1937-16 December 2023: Furthering quantitative pharmacology through applied mathematics
err2024-09-23
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errDanhof, Meindert; van Der Graaf, Piet H.; Post, Teun M.; Visser, Sandra A. G.; Zuideveld, Klaas P.; Schmidt, Stephan
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A Pediatric Covariate Function for CYP3A-Mediated Midazolam Clearance Can Scale Clearance of Selected CYP3A Substrates in Children
err2019-06-27
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errBrussee, Janneke M.; Krekels, Elke H. J.; Calvier, Elisa A. M.; Palic, Semra; Rostami-Hodjegan, Amin; Danhof, Meindert; Barrett, Jeffrey S.; de Wildt, Saskia N.; Knibbe, Catherijne A. J.
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Sacubitril/valsartan (LCZ696) significantly reduces aldosterone and increases cGMP circulating levels in a canine model of RAAS activation
err2019-02-01
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errMochel, Jonathan P.; Teng, Chi Hse; Peyrou, Mathieu; Giraudel, Jerome; Danhof, Meindert; Rigel, Dean F.
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The implications of target saturation for the use of drug-target residence time
err2018-12-28
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errde Witte, Wilhelmus E. A.; Danhof, Meindert; van der Graaf, Piet H.; de lange, Elizabeth C. M.
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In vitro and in silico analysis of the effects of D2 receptor antagonist target binding kinetics on the cellular response to fluctuating dopamine concentrations
err2018-09-21
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errde Witte, Wilhelmus E. A.; Versfelt, Joost W.; Kuzikov, Maria; Rolland, Solene; Georgi, Victoria; Gribbon, Philip; Gul, Sheraz; Huntjens, Dymphy; van der Graaf, Piet Hein; Danhof, Meindert; Fernandez-Montalvan, Amaury; Witt, Gesa; de Lange, Elizabeth C. M.
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Extending a Systems Model of the APP Pathway: Separation of β- and γ-Secretase Sequential Cleavage Steps of APP
err2018-06-01
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errvan Maanen, Eline M. T.; van Steeg, Tamara J.; Ahsman, Maurice J.; Michener, Maria S.; Savage, Mary J.; Kennedy, Matthew E.; Kleijn, Huub Jan; Stone, Julie; Danhof, Meindert
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Drugs Being Eliminated via the Same Pathway Will Not Always Require Similar Pediatric Dose Adjustments
err2018-02-05
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errCalvier, Elisa A. M.; Krekels, Elke H. J.; Yu, Huixin; Valitalo, Pyry A. J.; Johnson, Trevor N.; Rostami-Hodjegan, Amin; Tibboel, Dick; van der Graaf, Piet H.; Danhof, Meindert; Knibbe, Catherijne A. J.
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Prediction of human CNS pharmacokinetics using a physiologically-based pharmacokinetic modeling approach
err2018-01-01
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errYamamoto, Yumi; Valitalo, Pyry A.; Wong, Yin Cheong; Huntjens, Dymphy R.; Proost, Johannes H.; Vermeulen, An; Krauwinkel, Walter; Beukers, Margot W.; Kokki, Hannu; Kokki, Merja; Danhof, Meindert; van Hasselt, Johan G. C.; de Lange, Elizabeth C. M.
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Target and Tissue Selectivity Prediction by Integrated Mechanistic Pharmacokinetic-Target Binding and Quantitative Structure Activity Modeling
err2017-12-04
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errVlot, Anna H. C.; de Witte, Wilhelmus E. A.; Danhof, Meindert; van der Graaf, Piet H.; van Westen, Gerard J. P.; de lange, Elizabeth C. M.
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Pharmacokinetic interactions and dosing rationale for antiepileptic drugs in adults and children
err2017-11-07
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errvan Dijkman, Sven C.; Rauwe, Willem M.; Danhof, Meindert; Della Pasqua, Oscar
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Individualized Dosing Algorithms and Therapeutic Monitoring for Antiepileptic Drugs
err2017-08-30
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errvan Dijkman, Sven C.; Wicha, Sebastian G.; Danhof, Meindert; Della Pasqua, Oscar E.
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Microdialysis: the Key to Physiologically Based Model Prediction of Human CNS Target Site Concentrations
err2017-03-09
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errYamamoto, Yumi; Danhof, Meindert; de Lange, Elizabeth C. M.
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Characterization and Prediction of Cardiovascular Effects of Fingolimod and Siponimod Using a Systems Pharmacology Modeling Approachs
err2017-02-01
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errSnelder, Nelleke; Ploeger, Bart A.; Luttringer, Olivier; Rigel, Dean F.; Webb, Randy L.; Feldman, David; Fu, Fumin; Beil, Michael; Jin, Liang; Stanski, Donald R.; Danhof, Meindert
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A Generic Multi-Compartmental CNS Distribution Model Structure for 9 Drugs Allows Prediction of Human Brain Target Site Concentrations
err2016-11-18
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errYamamoto, Yumi; Valitalo, Pyry A.; van den Berg, Dirk-Jan; Hartman, Robin; van den Brink, Willem; Wong, Yin Cheong; Huntjens, Dymphy R.; Proost, Johannes H.; Vermeulen, An; Krauwinkel, Walter; Bakshi, Suruchi; Aranzana-Climent, Vincent; Marchand, Sandrine; Dahyot-Fizelier, Claire; Couet, William; Danhof, Meindert; van Hasselt, Johan G. C.; de lange, Elizabeth C. M.
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The variability in beta-cell function in placebo-treated subjects with type 2 diabetes: application of the weight-HbA1c-insulin-glucose (WHIG) model
err2016-11-17
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errDuong, Janna K.; de Winter, Willem; Choy, Steve; Plock, Nele; Naik, Himanshu; Krauwinkel, Walter; Visser, Sandra A. G.; Verhamme, Katia M.; Sturkenboom, Miriam C.; Stricker, B. H.; Danhof, Meindert
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Translating QT interval prolongation from conscious dogs to humans
err2016-10-29
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errDubois, Vincent F. S.; Smania, Giovanni; Yu, Huixin; Graf, Ramona; Chain, Anne S. Y.; Danhof, Meindert; Della Pasqua, Oscar
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