John E. Pintar - Publications, H-index & Citations

John E. Pintar

umdnj-robert wood johnson medical school

64H指数

226论文数

1.3W被引数

收录论文 67

发表时间

Synthesis and Pharmacology of a Morphinan-Derived Dual Mu–Kappa Opioid Receptor Agonist Analgesic 吗啡烷衍生物双效μ-κ阿片受体激动剂镇痛药的合成与药理学

ACS Chemical Neuroscience

IF3.9

2025-06-26

PREAI

Balazs R. Varga; Rajendra Uprety; Barnali Paul; Alexis Knoll; Nokomis Ramos-Gonzalez; Kevin Appourchaux; Tori Taylor; Bengisu Turgutalp; Ryosuke Shinouchi; Shainnel O. Eans; Ashai K. Williams; Steven G. Vasquez-Grinnell; Saheem Zaidi; Antonina L. Nazarova; Andras Varadi; Valerie Le Rouzic; Taylor G. Brown; Shani Martinez; Michael Ansonoff; Rebecca Notis Dardashti; Amanda Hunkele; Joan Subrath; Matthew Welch; Jin Xu; Grace C. Rossi; John Pintar; Gavril W. Pasternak; Vsevolod Katritch; Jay P. McLaughlin; Ying Xian Pan; Susruta Majumdar

Oxa-Iboga alkaloids lack cardiac risk and disrupt opioid use in animal models

NATURE COMMUNICATIONS

IF15.7

2024-09-20

OAAI

Havel, Vaclav; Kruegel, Andrew C.; Bechand, Benjamin; Mcintosh, Scot; Stallings, Leia; Hodges, Alana; Wulf, Madalee G.; Nelson, Mel; Hunkele, Amanda; Ansonoff, Michael; Pintar, John E.; Hwu, Christopher; Ople, Rohini S.; Abi-Gerges, Najah; Zaidi, Saheem A.; Katritch, Vsevolod; Yang, Mu; Javitch, Jonathan A.; Majumdar, Susruta; Hemby, Scott E.; Sames, Dalibor

Contribution of the Opioid System to the Antidepressant Effects of Fluoxetine

BIOLOGICAL PSYCHIATRY

IF9

2022-12-01

OAAI

Carazo-Arias, Elena; Nguyen, Phi T.; Kass, Marley; Jee, Hyun Jung; Nautiyal, Katherine M.; Magalong, Valerie; Coie, Lilian; Andreu, Valentine; Gergues, Mark M.; Khalil, Huzefa; Akil, Huda; Arcego, Danusa Mar; Meaney, Michael; Anacker, Christoph; Samuels, Benjamin A.; Pintar, John E.; Morozova, Irina; Kalachikov, Sergey; Hen, Rene

Oxidative Metabolism as a Modulator of Kratom's Biological Actions

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-11-16

OAAI

Chakraborty, Soumen; Uprety, Rajendra; Slocum, Samuel T.; Irie, Takeshi; Le Rouzic, Valerie; Li, Xiaohai; Wilson, Lisa L.; Scouller, Brittany; Alder, Amy F.; Kruegel, Andrew C.; Ansonoff, Michael; Varadi, Andras; Eans, Shainnel O.; Hunkele, Amanda; Allaoa, Abdullah; Kalra, Sanjay; Xu, Jin; Pan, Ying Xian; Pintar, John; Kivell, Bronwyn M.; Pasternak, Gavril W.; Cameron, Michael D.; McLaughlin, Jay P.; Sames, Dalibor; Majumdar, Susruta

Mu opioid receptors on hippocampal GABAergic interneurons are critical for the antidepressant effects of tianeptine

NEUROPSYCHOPHARMACOLOGY

IF7.1

2021-09-30

OAAI

Han, Jaena; Andreu, Valentine; Langreck, Cory; Pekarskaya, Elizabeth A.; Grinnell, Steven G.; Allain, Florence; Magalong, Valerie; Pintar, John; Kieffer, Brigitte L.; Harris, Alexander Z.; Javitch, Jonathan A.; Hen, Rene; Nautiyal, Katherine M.

Site selective C-H functionalization of Mitragyna alkaloids reveals a molecular switch for tuning opioid receptor signaling efficacy

NATURE COMMUNICATIONS

IF15.7

2021-06-22

OAAI

Bhowmik, Srijita; Galeta, Juraj; Havel, Vaclav; Nelson, Melissa; Faouzi, Abdelfattah; Bechand, Benjamin; Ansonoff, Mike; Fiala, Tomas; Hunkele, Amanda; Kruegel, Andrew C.; Pintar, John E.; Majumdar, Susruta; Javitch, Jonathan A.; Sames, Dalibor

Regulation of Opioid Receptors by Their Endogenous Opioid Peptides

CELLULAR AND MOLECULAR NEUROBIOLOGY

IF4.8

2021-01-02

OAAI

Gupta, Achla; Gullapalli, Srinivas; Pan, Hui; Ramos-Ortolaza, Dinah L.; Hayward, Michael D.; Low, Malcom J.; Pintar, John E.; Devi, Lakshmi A.; Gomes, Ivone

Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2020-11-10

OAAI

Faouzi, Abdelfattah; Uprety, Rajendra; Gomes, Ivone; Massaly, Nicolas; Keresztes, Attila, I; Le Rouzic, Valerie; Gupta, Achla; Zhang, Tiffany; Yoon, Hye Jean; Ansonoff, Michael; Allaoa, Abdullah; Pan, Ying Xian; Pintar, John; Moron, Jose A.; Streicher, John M.; Devi, Lakshmi A.; Majumdar, Susruta

PAM haploinsufficiency does not accelerate the development of diet and human IAPP-induced diabetes in mice (vol 63, pg 561, 2020)PAM单倍不足不会加速小鼠饮食和人类IAPP诱导的糖尿病的发展 (第63卷，561页，2020)

DIABETOLOGIA

IF10.2

2020-03-14

OAAI

Chen, Yi-Chun; Mains, Richard E.; Eipper, Betty A.; Hoffman, Brad G.; Czyzyk, Traci A.; Pintar, John E.; Verchere, C. Bruce

PAM haploinsufficiency does not accelerate the development of diet- and human IAPP-induced diabetes in mice PAM单倍不足不会加速饮食和人类IAPP诱导的小鼠糖尿病的发展

DIABETOLOGIA

IF10.2

2020-01-27

OAAI

Chen, Yi-Chun; Mains, Richard E.; Eipper, Betty A.; Hoffman, Brad G.; Czyzyk, Traci A.; Pintar, John E.; Verchere, C. Bruce

7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects

ACS CENTRAL SCIENCE

IF10.4

2019-05-29

137

OAAI

Kruegel, Andrew C.; Uprety, Rajendra; Grinnell, Steven G.; Langreck, Cory; Pekarskaya, Elizabeth A.; Le Rouzic, Valerie; Ansonoff, Michael; Gassaway, Madalee M.; Pintar, John E.; Pasternak, Gavril W.; Javitch, Jonathan A.; Majumdar, Susruta; Sames, Dalibor

Contrasting effects of IGF binding protein-3 expression in mammary tumor cells and the tumor microenvironment

EXPERIMENTAL CELL RESEARCH

IF3.5

2019-01-01

PREAI

Scully, Tiffany; Scott, Carolyn D.; Firth, Sue M.; Pintar, John E.; Twigg, Stephen M.; Baxter, Robert C.

Editorial: Current Perspectives on Insulin-Like Growth Factor Binding Protein (IGFBP) Research

FRONTIERS IN ENDOCRINOLOGY

IF4.6

2018-11-20

OAAI

Hoeflich, Andreas; Pintar, John; Forbes, Briony

Enhancement of mammary tumour growth by IGFBP-3 involves impaired T cell accumulation

ENDOCRINE-RELATED CANCER

IF4.6

2018-02-01

OAAI

Scully, Tiffany; Scott, Carolyn D.; Firth, Sue M.; Sedger, Lisa M.; Pintar, John E.; Twigg, Stephen M.; Baxter, Robert C.

Opioids and opioid receptors orchestrate wound repair

TRANSLATIONAL RESEARCH

IF5.9

2017-07-01

OAAI

Wang, Ping; Gupta, Mihir; Poonawala, Tasneem; Farooqui, Mariya; Li, Yunfang; Peng, Fei; Rao, Sheldon; Ansonoff, Michael; Pintar, John E.; Gupta, Kalpna

Mexneurin is a novel precursor of peptides in the central nervous system of rodents

FEBS LETTERS

IF3

2017-06-01

OAAI

Matus-Ortega, Maura E.; Leff Gelman, Philippe; Calva-Nieves, Juan C.; Flores-Zamora, Anabel; Salazar-Juarez, Alberto; Torner-Aguilar, Carlos-Alejandro; Gamba, Gerardo; De Los Heros, Paola; Peng, Bonnie; Pintar, John E.; Gompf, Heinrich S.; Allen, Charles N.; Anton-Palma, Benito

The Behavioral Effects of the Antidepressant Tianeptine Require the Mu-Opioid Receptor

NEUROPSYCHOPHARMACOLOGY

IF7.1

2017-03-17

OAAI

Samuels, Benjamin Adam; Nautiyal, Katherine M.; Kruegel, Andrew C.; Levinstein, Marjorie R.; Magalong, Valerie M.; Gassaway, Madalee M.; Grinnell, Steven G.; Han, Jaena; Ansonoff, Michael A.; Pintar, John E.; Javitch, Jonathan A.; Sames, Dalibor; Hen, Rene

Tetrapeptide Endomorphin Analogs Require Both Full Length and Truncated Splice Variants of the Mu Opioid Receptor Gene Oprm1 for Analgesia

ACS CHEMICAL NEUROSCIENCE

IF3.9

2016-10-10

OAAI

Marrone, Gina F.; Lu, Zhigang; Rossi, Grace; Narayan, Ankita; Hunkele, Amanda; Marx, Sarah; Xu, Jin; Pintar, John; Majumdar, Susruta; Pan, Ying-Xian; Pasternak, Gavril W.

Insulin-like growth factor binding protein-3 (IGFBP-3) enhances obesity-related breast tumorigenesis

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Scully, Tiffany; Scott, Carolyn D.; de Silva, Hasanthi C.; Firth, Sue M.; Twigg, Stephen M.; Pintar, John E.; Baxter, Robert C.

A Novel Nociceptin Receptor Antagonist LY2940094 Inhibits Excessive Feeding Behavior in Rodents: A Possible Mechanism for the Treatment of Binge Eating Disorder

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2016-02-01

OAAI

Statnick, Michael A.; Chen, Yanyun; Ansonoff, Michael; Witkin, Jeffrey M.; Rorick-Kehn, Linda; Suter, Todd M.; Song, Min; Hu, Charlie; Lafuente, Celia; Jimenez, Alma; Benito, Ana; Diaz, Nuria; Angeles Martinez-Grau, Maria; Toledo, Miguel A.; Pintar, John E.

研究方向