未登录SARS-CoV-2 3CLpro mutations T21I and E166A confer differential resistance to simnotrelvir, bofutrelvir, and ensitrelvirSARS-CoV-2 3CLpro突变T21I和E166A对simnotrelvir、bofutrelvir和ensitrelvir产生不同的抗药性
Chen, Lu; Su, Haixia; Shang, Weijuan; Nie, Tianqing; Kuang, Wenhua; Wang, Chenchen; Shao, Qiang; Zhang, Leike; Liu, Wen; Xu, Yechun; Zhang, Yumin
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收藏Structure-based design of potent and selective inhibitors targeting RIPK3 for eliminating on-target toxicity in vitro基于结构的针对RIPK3的强效且选择性抑制剂的体外设计,以消除靶向毒性
Su, Haixia; Chen, Guofeng; Xie, Hang; Li, Wanchen; Xiong, Muya; He, Jian; Hu, Hangchen; Zhao, Wenfeng; Shao, Qiang; Li, Minjun
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收藏Dynamic Cap-Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease盖帽动态调控的猴痘病毒I7L蛋白酶底物通道及高效抑制剂设计
Su, HX; Wu, GQ; Xiong, MY; Wang, YH; Cao, JY; You, MY; Xiang, YC; Nie, TQ; Li, MJ; Xiao, GF; Zhang, LK; Shao, Q; Xu, YC
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收藏Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers
Wang, Xinwei; Wang, Mu; Xu, Tuo; Feng, Ye; Shao, Qiang; Han, Shuo; Chu, Xiaojing; Xu, Yechun; Lin, Shuling; Zhao, Qiang; Wu, Beili
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