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Comparison of the mechanism of antimicrobial action of the gold(I) compound auranofin in Gram-positive and Gram-negative bacteria Quadros Barse, Laisa; Ulfig, Agnes; Varatnitskaya, Marharyta; Vazquez-Hernandez, Melissa; Yoo, Jihyun; Imann, Astrid M.; Lupilov, Natalie; Fischer, Marina; Becker, Katja; Bandow, Julia E.; Leichert, Lars I. 分享 收藏
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Identification and characterisation of the tegument-expressed aldehyde dehydrogenase SmALDH_312 of Schistosoma mansoni, a target of disulfiram Beutler, Mandy; Harnischfeger, Julie; Weber, Michael H. W.; Hahnel, Steffen R.; Quack, Thomas; Blohm, Ariane; Ueberall, Monique E.; Timm, Thomas; Lochnit, Gunter; Rennar, Georg A.; Gallinger, Tom L.; Houhou, Hicham; Rahlfs, Stefan; Falcone, Franco H.; Becker, Katja; Schlitzer, Martin; Haeberlein, Simone; Czermak, Peter; Salzig, Denise; Grevelding, Christoph G. 分享 收藏
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Structure and Function of Redox-Sensitive Superfolder Green Fluorescent Protein Variant Heimsch, Kim C.; Gertzen, Christoph G. W.; Schuh, Anna Katharina; Nietzel, Thomas; Rahlfs, Stefan; Przyborski, Jude M.; Gohlke, Holger; Schwarzlaender, Markus; Becker, Katja; Fritz-Wolf, Karin 分享 收藏
An Optimized Dihydrodibenzothiazepine Lead Compound (SBI-0797750) as a Potent and Selective Inhibitor of Plasmodium falciparum and P. vivax Glucose 6-Phosphate Dehydrogenase 6-Phosphogluconolactonase Berneburg, Isabell; Peddibhotla, Satyamaheshwar; Heimsch, Kim C.; Haeussler, Kristina; Maloney, Patrick; Gosalia, Palak; Preuss, Janina; Rahbari, Mahsa; Skorokhod, Oleksii; Valente, Elena; Ulliers, Daniela; Simula, Luigi Felice; Buchholz, Kathrin; Hedrick, Michael P.; Hershberger, Paul; Chung, Thomas D. Y.; Jackson, Michael R.; Schwarzer, Evelin; Rahlfs, Stefan; Bode, Lars; Becker, Katja; Pinkerton, Anthony B. 分享 收藏
Cyclic 5-membered disulfides are not selective substrates of thioredoxin reductase, but are opened nonspecifically Felber, Jan G.; Poczka, Lena; Scholzen, Karoline C.; Zeisel, Lukas; Maier, Martin S.; Busker, Sander; Theisen, Ulrike; Brandstaedter, Christina; Becker, Katja; Arner, Elias S. J.; Thorn-Seshold, Julia; Thorn-Seshold, Oliver 分享 收藏
Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells Johnson, Fraser D.; Ferrarone, John; Liu, Alvin; Brandstaedter, Christina; Munuganti, Ravi; Farnsworth, Dylan A.; Lu, Daniel; Luu, Jennifer; Sihota, Tianna; Jansen, Sophie; Nagelberg, Amy; Shi, Rocky; Forcina, Giovanni C.; Zhang, Xu; Cheng, Grace S. W.; Miko, Sandra E. Spencer; de Rappard-Yuswack, Georgia; Sorensen, Poul H.; Dixon, Scott J.; Guha, Udayan; Becker, Katja; Djaballah, Hakim; Somwar, Romel; Varmus, Harold; Morin, Gregg B.; Lockwood, William W. 分享 收藏
Peroxide Antimalarial Drugs Target Redox Homeostasis in Plasmodium falciparum Infected Red Blood Cells Siddiqui, Ghizal; Giannangelo, Carlo; De Paoli, Amanda; Schuh, Anna Katharina; Heimsch, Kim C.; Anderson, Dovile; Brown, Timothy G.; MacRaild, Christopher A.; Wu, Jianbo; Wang, Xiaofang; Dong, Yuxiang; Vennerstrom, Jonathan L.; Becker, Katja; Creek, Darren J. 分享 收藏
1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity Legru, Alice; Verdirosa, Federica; Hernandez, Jean-Francois; Tassone, Giusy; Sannio, Filomena; Benvenuti, Manuela; Conde, Pierre-Alexis; Bossis, Guillaume; Thomas, Caitlyn A.; Crowder, Michael W.; Dillenberger, Melissa; Becker, Katja; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Gavara, Laurent 分享 收藏
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Selective, Modular Probes for Thioredoxins Enabled by Rational Tuning of a Unique Disulfide Structure Motif Felber, Jan G.; Zeisel, Lukas; Poczka, Lena; Scholzen, Karoline; Busker, Sander; Maier, Martin S.; Theisen, Ulrike; Brandstaedter, Christina; Becker, Katja; Arner, Elias S. J.; Thorn-Seshold, Julia; Thorn-Seshold, Oliver 分享 收藏
Plasmodium falciparum Ferredoxin-NADP+ Reductase-Catalyzed Redox Cycling of Plasmodione Generates Both Predicted Key Drug Metabolites: Implication for Antimalarial Drug Development Cichocki, Bogdan Adam; Donzel, Maxime; Heimsch, Kim C.; Lesanavicius, Mindaugas; Feng, Liwen; Montagut, Enrique Jose; Becker, Katja; Aliverti, Alessandro; Elhabiri, Mourad; Cenas, Narimantas; Davioud-Charvet, Elisabeth 分享 收藏
4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors Gavara, Laurent; Sevaille, Laurent; De Luca, Filomena; Mercuri, Paola; Bebrone, Carine; Feller, Georges; Legru, Alice; Cerboni, Giulia; Tanfoni, Silvia; Baud, Damien; Cutolo, Giuliano; Bestgen, Benoit; Chelini, Giulia; Verdirosa, Federica; Sannio, Filomena; Pozzi, Cecilia; Benvenuti, Manuela; Kwapien, Karolina; Fischer, Marina; Becker, Katja; Frere, Jean-Marie; Mangani, Stefano; Gresh, Nohad; Berthomieu, Dorothee; Galleni, Moreno; Docquier, Jean-Denis; Hernandez, Jean-Francois 分享 收藏
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In-vitro safety and off-target profile of the anti-parasitic arylmethylaminosteroid 1o Blum, Leonard; Gul, Sheraz; Ulshofer, Thomas; Henke, Marina; Krieg, Reimar; Berneburg, Isabell; Thomas, Dominique; Trautmann, Sandra; Kurz, Jennifer; Geyer, Joachim; Geisslinger, Gerd; Becker, Katja; Parnham, Michael J.; Schiffmann, Susanne 分享 收藏
Insights into the intracellular localization, protein associations and artemisinin resistance properties of Plasmodium falciparum K13 Gnadig, Nina F.; Stokes, Barbara H.; Edwards, Rachel L.; Kalantarov, Gavreel F.; Heimsch, Kim C.; Kuderjavy, Michal; Crane, Audrey; Lee, Marcus C. S.; Straimer, Judith; Becker, Katja; Trakht, Ilya N.; John, Audrey R. Odom; Mok, Sachel; Fidock, David A. 分享 收藏
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Biological activity and stability analyses of knipholone anthrone, a phenyl anthraquinone derivative isolated from Kniphofia foliosa Hochst Feilcke, Ruth; Arnouk, Georgette; Raphane, Boingotlo; Richard, Khumoekae; Tietjen, Ian; Andrae-Marobela, Kerstin; Erdmann, Frank; Schipper, Susanne; Becker, Katja; Arnold, Norbert; Frolov, Andrej; Reiling, Norbert; Imming, Peter; Fobofou, Serge A. T. 分享 收藏
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