Bruce S. Klein - Publications, H-index & Citations

Bruce S. Klein

University of Wisconsin System

62H指数

239论文数

1.2W被引数

收录论文 88

发表时间

Endoglucanase 2 (Eng2), a shared immunodominant antigen in dimorphic fungi that elicits immunity during infection 内切葡聚糖酶2 (Eng2)，一种在双态真菌中共享的免疫优势抗原，可在感染期间诱导免疫反应。

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2025-11-17

OAAI

Okaa, Uju J.; Taira, Cleison Ledesma; Dias, Lucas Dos Santos; Dobson, Hannah; Kujoth, Gregory C.; Campuzano, Althea; Homan, E. Jane; Thompson, George R.; Hung, Chiung-Yu; Deepe Jr, George S.; Wuthrich, Marcel; Klein, Bruce S.

Single-cell analysis of human airway epithelium identifies cell-type-specific responses to Aspergillus and Coccidioides 人呼吸道上皮的单细胞分析确定了Aspergillus和Coccidioides的细胞类型特异性反应

MBIO

IF4.7

2025-10-01

PREAI

Harding, Alfred T.; Crossen, Arianne J.; Zhang, Yanting; Reedy, Jennifer L.; Basham, Kyle J.; Hepworth, Olivia W.; Shah, Viral S.; Brown Harding, Hannah; Surve, Manalee V.; Simaku, Patricia; Kwaku, Geneva N.; Jensen, Kirstine Nolling; Otto, Yohana; Ward, Rebecca A.; Thompson III, George R.; Klein, Bruce S.; Rajagopal, Jayaraj; Sen, Pritha; Haber, Adam L.; Vyas, Jatin M.

Immunity to fungi and vaccine considerations 对真菌的免疫力及疫苗考量

CELL HOST & MICROBE

IF18.7

2024-10-01

PREAI

Whitehead, Alexander J.; Woodring, Therese; Klein, Bruce S.

Vaccination with O-linked Mannans Protects against Systemic Candidiasis through Innate Lymphocyte Populations

JOURNAL OF IMMUNOLOGY

IF3.4

2024-08-07

PREAI

Taira, Cleison Ledesma; Dias, Lucas dos Santos; Lichtenberger, Sarah; Whitehead, Alexander J.; Kischkel, Brenda; Netea, Mihai G.; Klein, Bruce S.; Wutrich, Marcel

Sensitization with Fungal Protease Allergen Establishes Long-Lived, Allergenic Th Cell Memory in the Lung

JOURNAL OF IMMUNOLOGY

IF3.4

2024-03-15

PREAI

Shapiro, Abigail; Caballes, Nicolas W. S.; Vera, Rebecca N.; Klein, Bruce S.; Brennan, Paul J.; Wu, Yen-Fei; Wiesner, Darin L.

They shall not grow mold: Soldiers of innate and adaptive immunity to fungi

SEMINARS IN IMMUNOLOGY

IF7.8

2023-01-01

OAAI

Woodring, Therese; Deepe, George S.; Levitz, Stuart M.; Wuethrich, Marcel; Klein, Bruce S.

BACH2 in TRegs Limits the Number of Adipose Tissue Regulatory T Cells and Restrains Type 2 Immunity to Fungal Allergens

JOURNAL OF IMMUNOLOGY RESEARCH

IF3.6

2022-08-05

OAAI

Contreras, Amanda; Wiesner, Darin L.; Kingstad-Bakke, Brock; Lee, Woojong; Svaren, John P.; Klein, Bruce S.; Suresh, M.

SLAMF1 Is Dispensable for Vaccine-Induced T Cell Development but Required for Resistance to Fungal Infection

JOURNAL OF IMMUNOLOGY

IF3.4

2022-03-15

OAAI

Kohn, Elaine M.; Dias, Lucas dos Santos; Dobson, Hannah E.; He, Xin; Wang, Huafeng; Klein, Bruce S.; Wuethrich, Marcel

Variation in Host Resistance to Blastomyces dermatitidis: Potential Use of Genetic Reference Panels and Advances in Immunophenotyping of Diverse Mouse Strains

MBIO

IF4.7

2022-02-22

OAAI

Kohn, Elaine M.; Taira, Cleison; Dobson, Hanah; Dias, Lucas Dos Santos; Okaa, Uju; Wiesner, Darin L.; Wuthrich, Marcel; Klein, Bruce S.

Combination Adjuvants Enhance Recombinant Protein Vaccine Protection against Fungal Infection

MBIO

IF4.7

2021-08-31

OAAI

Wuethrich, Marcel; Dobson, Hannah E.; Taira, Cleison Ledesma; Okaa, Uju Joy; Dias, Lucas dos Santos; Isidoro-Ayza, Marcos; Petrovsky, Nikolai; Klein, Bruce S.

LYSMD3: A mammalian pattern recognition receptor for chitin

CELL REPORTS

IF6.9

2021-07-01

OAAI

He, Xin; Howard, Brad A.; Liu, Yang; Neumann, Aaron K.; Li, Liwu; Menon, Nidhi; Roach, Tiffany; Kale, Shiv D.; Samuels, David C.; Li, Hongyan; Kite, Trenton; Kita, Hirohito; Hu, Tony Y.; Luo, Mengyao; Jones, Caroline N.; Okaa, Uju Joy; Squillace, Diane L.; Klein, Bruce S.; Lawrence, Christopher B.

Structural basis of Blastomyces Endoglucanase-2 adjuvancy in anti-fungal and -viral immunity

PLOS PATHOGENS

IF4.9

2021-03-18

OAAI

dos Santos Dias, Lucas; Dobson, Hannah E.; Bakke, Brock Kingstad; Kujoth, Gregory C.; Huang, Junfeng; Kohn, Elaine M.; Taira, Cleison Ledesma; Wang, Huafeng; Supekar, Nitin T.; Fites, J. Scott; Gates, Daisy; Gomez, Christina L.; Specht, Charles A.; Levitz, Stuart M.; Azadi, Parastoo; Li, Lingjun; Suresh, Marulasiddappa; Klein, Bruce S.; Wuthrich, Marcel

Spleen Tyrosine Kinase Is a Critical Regulator of Neutrophil Responses to Candida Species

MBIO

IF4.7

2020-06-30

OAAI

Negoro, Paige E.; Xu, Shuying; Dagher, Zeina; Hopke, Alex; Reedy, Jennifer L.; Feldman, Michael B.; Khan, Nida S.; Viens, Adam L.; Alexander, Natalie J.; Atallah, Natalie J.; Scherer, Allison K.; Dutko, Richard A.; Jeffery, Jane; Kernien, John F.; Fites, J. Scott; Nett, Jeniel E.; Klein, Bruce S.; Vyas, Jatin M.; Irimia, Daniel; Sykes, David B.; Mansour, Michael K.

Threats Posed by the Fungal Kingdom to Humans, Wildlife, and Agriculture 真菌王国对人类、野生动物和农业构成的威胁

MBIO

IF4.7

2020-06-30

325

OAAI

Fisher, Matthew C.; Gurr, Sarah J.; Cuomo, Christina A.; Blehert, David S.; Jin, Hailing; Stukenbrock, Eva H.; Stajich, Jason E.; Kahmann, Regine; Boone, Charles; Denning, David W.; Gow, Neil A. R.; Klein, Bruce S.; Kronstad, James W.; Sheppard, Donald C.; Taylor, John W.; Wright, Gerard D.; Heitman, Joseph; Casadevall, Arturo; Cowen, Leah E.

Early immune response against Fonsecaea pedrosoi requires Dectin-2-mediated Th17 activity, whereas Th1 response, aided by Treg cells, is crucial for fungal clearance in later stage of experimental chromoblastomycosis

PLOS NEGLECTED TROPICAL DISEASES

IF3.4

2020-06-15

OAAI

Siqueira, Isaque Medeiros; Wuthrich, Marcel; Li, Mengyi; Wang, Huafeng; La-Casas, Lucas de Oliveira; de Castro, Raffael Junio Araujo; Klein, Bruce; Bocca, Anamelia Lorenzetti

CARD9-Associated Dectin-1 and Dectin-2 Are Required for Protective Immunity of a Multivalent Vaccine against Coccidioides posadasii Infection

JOURNAL OF IMMUNOLOGY

IF3.4

2020-06-15

OAAI

Campuzano, Althea; Zhang, Hao; Ostroff, Gary R.; Dias, Lucas dos Santos; Wuthrich, Marcel; Klein, Bruce S.; Yu, Jieh-Juen; Lara, Humberto H.; Lopez-Ribot, Jose L.; Hung, Chiung-Yu

Antigen discovery unveils resident memory and migratory cell roles in antifungal resistance

MUCOSAL IMMUNOLOGY

IF7.6

2020-05-01

OAAI

Dobson, Hannah E.; Dias, Lucas Dos Santos; Kohn, Elaine M.; Fites, Scott; Wiesner, Darin L.; Dileepan, Thamotharampillai; Kujoth, Gregory C.; Abraham, Ambily; Ostroff, Gary R.; Klein, Bruce S.; Wuthrich, Marcel

Infectious particle identity determines dissemination and disease outcome for the inhaled human fungal pathogen Cryptococcus

PLOS PATHOGENS

IF4.9

2019-06-27

OAAI

Walsh, Naomi M.; Botts, Michael R.; McDermott, Andrew J.; Ortiz, Sebastien C.; Wuthrich, Marcel; Klein, Bruce; Hull, Christina M.

Investigation of Genetic Susceptibility to Blastomycosis Reveals Interleukin-6 as a Potential Susceptibility Locus

MBIO

IF4.7

2019-06-25

OAAI

Merkhofer, Richard M., Jr.; O'Neill, Mary B.; Xiong, Donny; Hernandez-Santos, Nydiaris; Dobson, Hannah; Fites, J. Scott; Shockey, Abigail C.; Wuethrich, Marcel; Pepperell, Caitlin S.; Klein, Bruce S.

Virally-vectored vaccine candidates against white-nose syndrome induce anti-fungal immune response in little brown bats (Myotis lucifugus)

SCIENTIFIC REPORTS

IF3.9

2019-05-01

OAAI

Rocke, Tonie E.; Kingstad-Bakke, Brock; Wuthrich, Marcel; Stading, Ben; Abbott, Rachel C.; Isidoro-Ayza, Marcos; Dobson, Hannah E.; Dias, Lucas dos Santos; Galles, Kevin; Lankton, Julia S.; Falendysz, Elizabeth A.; Lorch, Jeffrey M.; Fites, J. Scott; Lopera-Madrid, Jaime; White, J. Paul; Klein, Bruce; Osorio, Jorge E.

研究方向