César A. López - Publications, H-index & Citations

César A. López

Los Alamos National Laboratory

30H指数

133论文数

5.2K被引数

收录论文 46

发表时间

Dynamics and lipid membrane coupling of the RAS-RAF complex revealed via multiscale simulations RAS-RAF复合物的动力学及与脂质膜的耦合关系通过多尺度模拟揭示

Biophysical Journal

IF3.1

2025-08-22

OAAI

Timothy S. Carpenter; Fikret Aydin; Chris Neale; Que N. Van; Xiaohua Zhang; Harsh Bhatia; Jason W. Sidabras; Peter H. Frank; Konstantia Georgouli; Jeremy O.B. Tempkin; Violeta Burns Casamayor; Gulcin Gulten; Rebika Shrestha; Debanjan Goswami; Francesco Di Natale; Joseph R. Chavez; Adam Moody; Joseph Y. Moon; Tomas Oppelstrup; James N. Glosli; Gautham Dharuman; Sergio Wong; Shusen Liu; Nicolas W. Hengartner; Cesar A. López; Kien Nguyen; Christopher B. Stanley; Liam G. Stanton; Lara Patel; Tyler Reddy; Thomas J. Turbyville; Brian Van Essen; Peer-Timo Bremer; Felice C. Lightstone; Andrew G. Stephen; Sandrasegaram Gnanakaran; Frank McCormick; Dwight V. Nissley; Frederick H. Streitz; Helgi I. Ingólfsson

A blueprint for biomolecular condensation driven by bacterial microcompartment encapsulation peptides 由细菌微隔室包封肽驱动的生物分子凝聚的蓝图

Nature Communications

IF15.7

2025-08-11

OAAI

Daniel S. Trettel; Cesar A. López; Eliana Rodriguez; Babetta L. Marrone; Cesar Raul Gonzalez-Esquer

Influence of membrane on the antigen presentation of the HIV-1 envelope membrane proximal external region (MPER)

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2024-10-01

PREAI

Lopez, Cesar A.; Alam, S. Munir; Derdeyn, Cynthia A.; Haynes, Barton F.; Gnanakaran, Sandrasegaram

Predicting permeation of compounds across the outer membrane of P. aeruginosa using molecular descriptors

COMMUNICATIONS CHEMISTRY

IF6.2

2024-04-12

OAAI

Manrique, Pedro D.; Leus, Inga V.; Lopez, Cesar A.; Mehla, Jitender; Malloci, Giuliano; Gervasoni, Silvia; Vargiu, Attilio V.; Kinthada, Rama K.; Herndon, Liam; Hengartner, Nicolas W.; Walker, John K.; Rybenkov, Valentin V.; Ruggerone, Paolo; Zgurskaya, Helen I.; Gnanakaran, S.

Membrane lipids drive formation of KRAS4b-RAF1 RBDCRD nanoclusters on the membrane (vol 7, 242 , 2024)

COMMUNICATIONS BIOLOGY

IF5.1

2024-04-11

OAAI

Shrestha, Rebika; Carpenter, Timothy S.; Van, Que N.; Agamasu, Constance; Tonelli, Marco; Aydin, Fikret; Chen, De; Gulten, Gulcin; Glosli, James N.; Lopez, Cesar A.; Oppelstrup, Tomas; Neale, Chris; Gnanakaran, Sandrasegaram; Gillette, William K.; Ingolfsson, Helgi I.; Lightstone, Felice C.; Stephen, Andrew G.; Streitz, Frederick H.; Nissley, Dwight V.; Turbyville, Thomas J.

Membrane lipids drive formation of KRAS4b-RAF1 RBDCRD nanoclusters on the membrane 膜脂驱动膜上KRAS4b-RAF1 RBDCRD纳米簇的形成

COMMUNICATIONS BIOLOGY

IF5.1

2024-02-28

OAAI

Direct Modulators of K-Ras-Membrane Interactions

ACS CHEMICAL BIOLOGY

IF3.8

2023-08-14

OAAI

Morstein, Johannes; Shrestha, Rebika; Van, Que N.; Lopez, Cesar A.; Arora, Neha; Tonelli, Marco; Liang, Hong; Chen, De; Zhou, Yong; Hancock, John F.; Stephen, Andrew G.; Turbyville, Thomas J.; Shokat, Kevan M.

Machine Learning-Driven Multiscale Modeling: Bridging the Scales with a Next-Generation Simulation Infrastructure 机器学习驱动的多尺度建模: 用下一代仿真基础设施桥接尺度

JOURNAL OF CHEMICAL THEORY AND COMPUTATION

IF5.5

2023-04-19

OAAI

Ingolfsson, Helgi I.; Bhatia, Harsh; Aydin, Fikret; Oppelstrup, Tomas; Lopez, Cesar A.; Stanton, Liam G.; Carpenter, Timothy S.; Wong, Sergio; Di Natale, Francesco; Zhang, Xiaohua; Moon, Joseph Y.; Stanley, Christopher B.; Chavez, Joseph R.; Nguyen, Kien; Dharuman, Gautham; Burns, Violetta; Shrestha, Rebika; Goswami, Debanjan; Gulten, Gulcin; Van, Que N.; Ramanathan, Arvind; Van Essen, Brian; Hengartner, Nicolas W.; Stephen, Andrew G.; Turbyville, Thomas; Bremer, Peer-Timo; Gnanakaran, S.; Glosli, James N.; Lightstone, Felice C.; Nissley, Dwight V.; Streitz, Frederick H.

New understanding of multidrug efflux and permeation in antibiotic resistance, persistence, and heteroresistance

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES

IF4.8

2022-11-07

OAAI

Manrique, Pedro D.; Lopez, Cesar A.; Gnanakaran, S.; Rybenkov, Valentin V.; Zgurskaya, Helen, I

Acoustic force spectroscopy reveals subtle differences in cellulose unbinding behavior of carbohydrate-binding modules

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-10-10

OAAI

Hackl, Markus; Contrada, Edward V.; Ash, Jonathan E.; Kulkarni, Atharv; Yoon, Jinho; Cho, Hyeon-Yeol; Lee, Ki-Bum; Yarbrough, John M.; Lopez, Cesar A.; Gnanakaran, Sandrasegaram; Chundawat, Shishir P. S.

Exploring CRD mobility during RAS/RAF engagement at the membrane 在膜上的RAS/RAF接合期间探索CRD迁移率

BIOPHYSICAL JOURNAL

IF3.1

2022-10-01

OAAI

Nguyen, Kien; Lopez, Cesar A.; Neale, Chris; Van, Que N.; Carpenter, Timothy S.; Di Natale, Francesco; Travers, Timothy; Tran, Timothy H.; Chan, Albert H.; Bhatia, Harsh; Frank, Peter H.; Tonelli, Marco; Zhang, Xiaohua; Gulten, Gulcin; Reddy, Tyler; Burns, Violetta; Oppelstrup, Tomas; Hengartner, Nick; Simanshu, Dhirendra K.; Bremer, Peer-Timo; Chen, De; Glosli, James N.; Shrestha, Rebika; Turbyville, Thomas; Streitz, Frederick H.; Nissley, Dwight V.; Ingolfsson, Helgi I.; Stephen, Andrew G.; Lightstone, Felice C.; Gnanakaran, Sandrasegaram

Asynchronous Reciprocal Coupling of Martini 2.2 Coarse-Grained and CHARMM36 All-Atom Simulations in an Automated Multiscale Framework

JOURNAL OF CHEMICAL THEORY AND COMPUTATION

IF5.5

2022-07-22

OAAI

Lopez, Cesar A.; Zhang, Xiaohua; Aydin, Fikret; Shrestha, Rebika; Van, Que N.; Stanley, Christopher B.; Carpenter, Timothy S.; Nguyen, Kien; Patel, Lara A.; Chen, De; Burns, Violetta; Hengartner, Nicolas W.; Reddy, Tyler J. E.; Bhatia, Harsh; Di Natale, Francesco; Tran, Timothy H.; Chan, Albert H.; Simanshu, Dhirendra K.; V. Nissley, Dwight; Streitz, Frederick H.; Stephen, Andrew G.; Turbyville, Thomas J.; Lightstone, Felice C.; Gnanakaran, Sandrasegaram; Ingolfsson, Helgi I.; Neale, Chris

Machine learning-driven multiscale modeling reveals lipid-dependent dynamics of RAS signaling proteins 机器学习驱动的多尺度建模揭示了RAS信号蛋白的脂质依赖性动力学

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-01-04

OAAI

Ingolfsson, Helgi I.; Neale, Chris; Carpenter, Timothy S.; Shrestha, Rebika; Lopez, Cesar A.; Tran, Timothy H.; Oppelstrup, Tomas; Bhatia, Harsh; Stanton, Liam G.; Zhang, Xiaohua; Sundram, Shiv; Di Natale, Francesco; Agarwal, Animesh; Dharuman, Gautham; Schumacher, Sara I. L. Kokkila; Turbyville, Thomas; Gulten, Gulcin; Van, Que N.; Goswami, Debanjan; Jean-Francois, Frantz; Agamasu, Constance; Chen, De; Hettige, Jeevapani J.; Travers, Timothy; Sarkar, Sumantra; Surh, Michael P.; Yang, Yue; Moody, Adam; Liu, Shusen; Van Essen, Brian C.; Voter, Arthur F.; Ramanathan, Arvind; Hengartner, Nicolas W.; Simanshu, Dhirendra K.; Stephen, Andrew G.; Bremer, Peer-Timo; Gnanakaran, S.; Glosli, James N.; Lightstone, Felice C.; McCormick, Frank; Nissley, Dwight, V; Streitz, Frederick H.

Development of Martini 2.2 parameters for N-glycans: a case study of the HIV-1 Env glycoprotein dynamics N-聚糖的马提尼2.2参数的开发: HIV-1 Env糖蛋白动力学的案例研究

GLYCOBIOLOGY

IF3.3

2021-03-20

OAAI

Chakraborty, Srirupa; Wagh, Kshitij; Gnanakaran, S.; Lopez, Cesar A.

Predictive Rules of Efflux Inhibition and Avoidance in Pseudomonas aeruginosa

MBIO

IF4.7

2021-02-23

OAAI

Mehla, Jitender; Malloci, Giuliano; Mansbach, Rachael; Lopez, Cesar A.; Tsivkovski, Ruslan; Haynes, Keith; Leus, Inga, V; Grindstaff, Sally B.; Cascella, Robert H.; D'Cunha, Napoleon; Herndon, Liam; Hengartner, Nicolas W.; Margiotta, Enrico; Atzori, Alessio; Vargiu, Attilio V.; Manrique, Pedro D.; Walker, John K.; Lomovskaya, Olga; Ruggerone, Paolo; Gnanakaran, S.; Rybenkov, Valentin V.; Zgurskaya, Helen, I

Molecular origins of reduced activity and binding commitment of processive cellulases and associated carbohydrate-binding proteins to cellulose III

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-01

OAAI

Chundawat, Shishir P. S.; Nemmaru, Bhargava; Hackl, Markus; Brady, Sonia K.; Hilton, Mark A.; Johnson, Madeline M.; Chang, Sungrok; Lang, Matthew J.; Huh, Hyun; Lee, Sang-Hyuk; Yarbrough, John M.; Lopez, Cesar A.; Gnanakaran, Sandrasegaram

Visualization of the HIV-1 Env glycan shield across scales 跨尺度的HIV-1 Env聚糖屏蔽的可视化

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-10-22

OAAI

Berndsen, Zachary T.; Chakraborty, Srirupa; Wang, Xiaoning; Cottrell, Christopher A.; Torres, Jonathan L.; Diedrich, Jolene K.; Lopez, Cesar A.; Yates, John R., III; van Gils, Marit J.; Paulson, James C.; Gnanakaran, Sandrasegaram; Ward, Andrew B.

Uncovering a membrane-distal conformation of KRAS available to recruit RAF to the plasma membrane

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-09-10

OAAI

Van, Que N.; Lopez, Cesar A.; Tonelli, Marco; Taylor, Troy; Niu, Ben; Stanley, Christopher B.; Bhowmik, Debsindhu; Tran, Timothy H.; Frank, Peter H.; Messing, Simon; Alexander, Patrick; Scott, Daniel; Ye, Xiaoying; Drew, Matt; Chertov, Oleg; Losche, Mathias; Ramanathan, Arvind; Gross, Michael L.; Hengartner, Nicolas W.; Westler, William M.; Markley, John L.; Simanshu, Dhirendra K.; Nissley, Dwight, V; Gillette, William K.; Esposito, Dominic; McCormick, Frank; Gnanakaran, S.; Heinrich, Frank; Stephen, Andrew G.

Anionic Lipids Impact RAS-Binding Site Accessibility and Membrane Binding Affinity of CRAF RBD-CRD

BIOPHYSICAL JOURNAL

IF3.1

2020-08-01

OAAI

Travers, Timothy; Lopez, Cesar A.; Agamasu, Constance; Hettige, Jeevapani J.; Messing, Simon; Garcia, Angel E.; Stephen, Andrew G.; Gnanakaran, S.

Machine Learning Algorithm Identifies an Antibiotic Vocabulary for Permeating Gram-Negative Bacteria

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2020-05-26

OAAI

Mansbach, Rachael A.; Leus, Inga A.; Mehla, Jitender; Lopez, Cesar A.; Walker, John K.; Rybenkov, Valentin V.; Hengartner, Nicolas W.; Zgurskaya, Helen, I; Gnanakaran, S.

研究方向