Howard H. Yang - Publications, H-index & Citations

Howard H. Yang

national institutes of health

37H指数

340论文数

5.0K被引数

收录论文 87

发表时间

Cancer stem cells are hyper-responsive sensors of the tumour microenvironment and regulate metastasis dynamics through YAP/TAZ 癌症干细胞是肿瘤微环境的高响应性传感器，并通过YAP/TAZ调控转移动态

Nature Cell Biology

IF19.1

2026-07-27

OAAI

Binwu Tang; Jacob Minin; Victoria M. Gonzalez; Zoya Z. Khan; Andrew R. Gaines; Yuval Raviv; Yu-an Yang; Christine P. Carney; Zachary G. Millman; Daniel Grun; Cristiana M. Pineda; Alina Sharma; Dominic Esposito; Hualong Yan; Jing Huang; Andy D. Tran; Michael Kruhlak; Howard H. Yang; Maxwell P. Lee; Lalage M. Wakefield

Treatment of refractory pityriasis rubra pilaris with biologic therapy: a case series 生物制剂治疗难治性毛囊性 pityriasis rubra pilaris：一项病例系列研究

CLINICAL AND EXPERIMENTAL DERMATOLOGY

IF2.8

2025-07-01

PREAI

Han, Richard; Spratt, William R.; Yang, Howard; Lai, Francis Y. X.; Lee, Senhong

Applying multimodal AI to physiological waveforms improves genetic prediction of cardiovascular traits 应用多模态AI于生理波形可改善心血管性状的遗传预测

american journal of human genetics

IF0

2025-06-20

OAAI

Yuchen Zhou; Justin Khasentino; Taedong Yun; Mahantesh I. Biradar; Jacqueline Shreibati; Dongbing Lai; Tae-Hwi Schwantes-An; Robert Luben; Zachary R. McCaw; Jorgen Engmann; Rui Providencia; Amand Floriaan Schmidt; Patricia B. Munroe; Howard Yang; Andrew Carroll; Anthony P. Khawaja; Cory Y. McLean; Babak Behsaz; Farhad Hormozdiari

Mutational signatures in 175 Chinese gastric cancer patients 175例中国胃癌患者的突变特征

BMC CANCER

IF3.4

2024-09-30

OAAI

Liu, Fatao; Hu, Nan; Jiang, Kewei; Liu, Huaitian; Wang, Mingyi; Hu, Ying; Zhang, Tongwu; Wu, Ho-Hsiang; Yang, Howard; Weng, Hao; Dong, Ping; Giffen, Carol; Zhu, Bin; Lee, Maxwell P.; Abnet, Christian C.; Taylor, Philip R.; Liu, Yun; Liu, Yingbin; Goldstein, Alisa M.

Mutant mice with rod-specific VPS35 deletion exhibit retinal α-synuclein pathology-associated degeneration

NATURE COMMUNICATIONS

IF15.7

2024-07-23

OAAI

Fu, Cheng; Yang, Nan; Chuang, Jen-Zen; Nakajima, Nobuyuki; Iraha, Satoshi; Roy, Neeta; Wu, Zhenquan; Jiang, Zhichun; Otsu, Wataru; Radu, Roxana A.; Yang, Howard Hua; Lee, Maxwell Ping; Worgall, Tilla S.; Xiong, Wen-Cheng; Sung, Ching-Hwa

Unsupervised representation learning on high-dimensional clinical data improves genomic discovery and prediction

NATURE GENETICS

IF31.8

2024-07-08

OAAI

Yun, Taedong; Cosentino, Justin; Behsaz, Babak; McCaw, Zachary R.; Hill, Davin; Luben, Robert; Lai, Dongbing; Bates, John; Yang, Howard; Schwantes-An, Tae-Hwi; Zhou, Yuchen; Khawaja, Anthony P.; Carroll, Andrew; Hobbs, Brian D.; Cho, Michael H.; Mclean, Cory Y.; Hormozdiari, Farhad

Protein phosphatase 6 activates NF-κB to confer sensitivity to MAPK pathway inhibitors in KRAS- and BRAF-mutant cancer cells

SCIENCE SIGNALING

IF6.6

2024-05-14

OAAI

Zhang, Haibo; Read, Abigail; Cataisson, Christophe; Yang, Howard H.; Lee, Wei-Chun; Turk, Benjamin E.; Yuspa, Stuart H.; Luo, Ji

Hyperprogressive disease following bintrafusp alfa and DNA damaging chemotherapy in relapsed small cell lung cancer

CANCER RESEARCH

IF16.6

2024-04-05

PREAI

Schroeder, Brett; Takahashi, Nobuyuki; Yang, Howard; Donahue, Renee; Skidmore, Zachary; Konicki, Alissa; Nirula, Michael; Greenberg, Max; Chrisafis, George; Zhang, Yang; Tsai, Yo-Ting; Sciuto, Linda; Nichols, Samantha; Abel, Melissa; Desai, Parth; Kumar, Rajesh; Schultz, Christopher; Pinkiert, Danielle; Graham, Chante; Sharma, Ajit; Malin, Justin; Krishnamurthy, Manan; Zhuang, Sophie; Lee, Maxwell; Rinaldi, Lorenzo; Schlom, Jeffrey; Wakefield, Lalage; Thomas, Anish

Single-cell transcriptional analysis of embryonic melanoblasts pinpoints embryonic cell states that underlie targeted therapy and immune checkpoint blockade resistance

CANCER RESEARCH

IF16.6

2024-04-05

PREAI

Gopalan, Vishaka; Wong, Chun Wai; Day, Chi-Ping; Perez-Guijarro, Eva; Lee, Maxwell P.; Jiang, Yuhong; Yang, Howard H.; Alves-Constantino, Maira; Sassano, Antonella; Smith, Cari; Simpson, Mark; Chin, Sung; Ebersole, Jessica; Gruen, Charli; Wu, Emily; Hannenhalli, Sridhar; Hurlstone, Adam; Merlino, Glenn; Marie, Kerrie

SOX9 is a key component of RUNX2-regulated transcriptional circuitry in osteosarcoma

CELL AND BIOSCIENCE

IF6.2

2023-07-25

OAAI

Kim, Young-Im; Tseng, Yu-Chou; Ayaz, Gamze; Wang, Shasha; Yan, Hualong; du Bois, Wendy; Yang, Howard; Zhen, Tao; Lee, Maxwell P. P.; Liu, Paul; Kaplan, Rosandra N.; Huang, Jing

Characterization and validation of a Smad3/TGFb pathway reporter mouse for analysis of TGFß signaling in normal homeostasis and cancer

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Yang, Yuan; Millman, Zachary; Stuelten, Christina; Gargesha, Madhu; Simpson, Mark; Yang, Howard; Lee, Maxwell; Wakefield, Lalage M.

Interrogating subclonal mechanisms of immune evasion and immunotherapy resistance in melanoma

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Church, Isabella; Gruen, Charli; Sassano, Antonella; Valencia, Julio; Wu, Emily; Yang, Howard; Needle, Gabe; Smith, Cari; Chin, Sung; Ebersole, Jessica; Marcelus, Christina; Fon, Anyen; Liu, Huaitian; Day, Chi-Ping; Young, Howard; Lee, Maxwell; Merlino, Glenn; Perez-Guijarro, Eva

Apoptosis-induced nuclear expulsion in tumor cells drives S100a4-mediated metastatic outgrowth through the RAGE pathway

NATURE CANCER

IF28.5

2023-03-27

OAAI

Park, Woo-Yong; Gray, Justin M.; Holewinski, Ronald J.; Andresson, Thorkell; So, Jae Young; Carmona-Rivera, Carmelo; Hollander, M. Christine; Yang, Howard H.; Lee, Maxwell; Kaplan, Mariana J.; Cappell, Steven D.; Yang, Li

Dysregulation of Mitochondrial Translation Caused by CBFB Deficiency Cooperates with Mutant PIK3CA and Is a Vulnerability in Breast Cancer CBFB缺陷引起的线粒体翻译失调与突变型PIK3CA协同，是乳腺癌的易损性

CANCER RESEARCH

IF16.6

2023-02-14

OAAI

Malik, Navdeep; Kim, Young -Im; Yan, Hualong; Tseng, Yu-Chou; du Bois, Wendy; Ayaz, Gamze; Tran, Andy D.; Vera-Ramirez, Laura; Yang, Howard; Michalowski, Aleksandra M.; Kruhlak, Michael; Lee, Maxwell; Hunter, Kent W.; Huang, Jing

DeepConsensus improves the accuracy of sequences with a gap-aware sequence transformer

NATURE BIOTECHNOLOGY

IF41.7

2022-09-01

PREAI

Baid, Gunjan; Cook, Daniel E.; Shafin, Kishwar; Yun, Taedong; Llinares-Lopez, Felipe; Berthet, Quentin; Belyaeva, Anastasiya; Topfer, Armin; Wenger, Aaron M.; Rowell, William J.; Yang, Howard; Kolesnikov, Alexey; Ammar, Waleed; Vert, Jean-Philippe; Vaswani, Ashish; McLean, Cory Y.; Nattestad, Maria; Chang, Pi-Chuan; Carroll, Andrew

The oxidoreductase CLIC4 is required to maintain mitochondrial function and resistance to exogenous oxidants in breast cancer cells

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-09-01

OAAI

Al Khamici, Heba; Sanchez, Vanesa C.; Yan, Hualong; Cataisson, Christophe; Michalowski, Aleksandra M.; Yang, Howard H.; Li, Luowei; Lee, Maxwell P.; Huang, Jing; Yuspa, Stuart H.

Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems

CLINICAL & EXPERIMENTAL METASTASIS

IF3.2

2022-08-08

OAAI

Khan, Imran; Gril, Brunilde; Hoshino, Ayuko; Yang, Howard H.; Lee, Maxwell P.; Difilippantonio, Simone; Lyden, David C.; Steeg, Patricia S.

DNA Methyltransferase 3B-Mediated Intratumoral Heterogeneity and Therapeutic Targeting in Breast Cancer Recurrence and Metastasis

MOLECULAR CANCER RESEARCH

IF4.7

2022-07-20

OAAI

So, Jae Young; Yang, Howard H.; Park, Woo Yong; Skrypek, Nicolas; Ishii, Hiroki; Chen, Jennifer M.; Lee, Maxwell P.; Yang, Li

Host CLIC4 expression in the tumor microenvironment is essential for breast cancer metastatic competence

PLOS GENETICS

IF3.7

2022-06-21

OAAI

Sanchez, Vanesa C.; Yang, Howard H.; Craig-Lucas, Alayna; Dubois, Wendy; Carofino, Brandi L.; Lack, Justin; Dwyer, Jennifer E.; Simpson, R. Mark; Cataisson, Christophe; Lee, Max P.; Luo, Ji; Hunter, Kent W.; Yuspa, Stuart H.

Neutrophil dynamics in the tumor microenvironment determines therapy efficacy and is regulated by microbiota

JOURNAL OF IMMUNOLOGY

IF3.4

2022-05-01

PREAI

Araya, Romina E.; Lam, Khiem C.; Huang, April; Chen, Quanyi; Di Modica, Martina; Lopes, Amelie; Yang, Howard; Liu, Huaitian; Lee, Maxwell P.; Goldszmid, Romina S.

研究方向