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Differential Effects of HDAC6 Inhibition Versus Knockout During Hepatic Ischemia-Reperfusion Injury Highlight Importance of HDAC6 C-terminal Zinc-finger Ubiquitin-binding Domain Concors, Seth J.; Hernandez, Paul T.; OBrien, Ciaran; DePaolo, John; Murken, Douglas R.; Aufhauser, David D.; Wang, Zhonglin; Xiong, Yan; Krumeich, Lauren; Ge, Guanghui; Beier, Ulf H.; Bhatti, Tricia R.; Kozikowski, Alan P.; Avelar, Leandro A. Alves; Kurz, Thomas; Hancock, Wayne W.; Levine, Matthew H. 分享 收藏
Comprehensive Mechanistic View of the Hydrolysis of Oxadiazole-Based Inhibitors by Histone Deacetylase 6 (HDAC6) Motlova, Lucia; Snajdr, Ivan; Kutil, Zsofia; Andris, Erik; Ptacek, Jakub; Novotna, Adela; Novakova, Zora; Havlinova, Barbora; Tueckmantel, Werner; Draberova, Helena; Majer, Pavel; Schutkowski, Mike; Kozikowski, Alan; Rulisek, Lubomir; Barinka, Cyril 分享 收藏
Histone Deacetylase 6 and Heat Shock Protein 90 Control the Functions of Foxp3+ T-Regulatory Cells de Zoeten, Edwin F.; Wang, Liqing; Butler, Kyle; Beier, Ulf H.; Akimova, Tatiana; Sai, Hong; Bradner, James E.; Mazitschek, Ralph; Kozikowski, Alan P.; Matthias, Patrick; Hancock, Wayne W. 分享 收藏
Epigenetic Regulation of Autophagy by the Methyltransferase G9a de Narvajas, Amaia Artal-Martinez; Gomez, Timothy S.; Zhang, Jin-San; Mann, Alexander O.; Taoda, Yoshiyuki; Gorman, Jacquelyn A.; Herreros-Villanueva, Marta; Gress, Thomas M.; Ellenrieder, Volker; Bujanda, Luis; Kim, Do-Hyung; Kozikowski, Alan P.; Koenig, Alexander; Billadeau, Daniel D. 分享 收藏
Tetrahydroquinoline-Capped Histone Deacetylase 6 Inhibitor SW-101 Ameliorates Pathological Phenotypes in a Charcot-Marie-Tooth Type 2A Mouse Model Shen, Sida; Picci, Cristina; Ustinova, Kseniya; Benoy, Veronick; Kutil, Zsofia; Zhang, Guiping; Tavares, Mauricio T.; Pavlicek, Jiri; Zimprich, Chad A.; Robers, Matthew B.; Van den Bosch, Ludo; Barinka, Cyril; Langley, Brett; Kozikowski, Alan P. 分享 收藏
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Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models Noonepalle, Satish; Shen, Sida; Ptacek, Jakub; Tavares, Mauricio T.; Zhang, Guiping; Stransk, Jan; Pavlicek, Jiri; Ferreira, Glaucio M.; Hadley, Melissa; Pelaez, Guido; Barinka, Cyril; Kozikowski, Alan P.; Villagra, Alejandro 分享 收藏
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Structural and in Vivo Characterization of Tubastatin A, a Widely Used Histone Deacetylase 6 Inhibitor Shen, Sida; Svoboda, Michal; Zhang, Guangming; Cavasin, Maria A.; Motlova, Lucia; McKinsey, Timothy A.; Eubanks, James H.; Barinka, Cyril; Kozikowski, Alan P. 分享 收藏
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Active Benzimidazole Derivatives Targeting the MmpL3 Transporter in Mycobacterium abscessus 靶向脓肿分枝杆菌中MmpL3转运蛋白的活性苯并咪唑衍生物 Raynaud, Clement; Daher, Wassim; Johansen, Matt D.; Roquet-Baneres, Francoise; Blaise, Mickael; Onajole, Oluseye K.; Kozikowski, Alan P.; Herrmann, Jean-Louis; Dziadek, Jaroslaw; Gobis, Katarzyna; Kremer, Laurent 分享 收藏
Continuous Activity Assay for HDAC11 Enabling Reevaluation of HDAC Inhibitors Kutil, Zsofia; Mikesova, Jana; Zessin, Matthes; Meleshin, Marat; Novakova, Zora; Alquicer, Glenda; Kozikowski, Alan; Sippl, Wolfgang; Barinka, Cyril; Schutkowski, Mike 分享 收藏
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Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells (vol 9, 6136, 2019) Knox, Tessa; Sahakian, Eva; Banik, Debarati; Hadley, Melissa; Palmer, Erica; Noonepalle, Satish; Kim, Jennifer; Powers, John; Gracia-Hernandez, Maria; Oliveira, Vasco; Cheng, Fengdong; Chen, Jie; Barinka, Cyril; Pinilla-Ibarz, Javier; Lee, Norman H.; Kozikowski, Alan; Villagra, Alejandro 分享 收藏
Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models Shen, Sida; Hadley, Melissa; Ustinova, Kseniya; Pavlicek, Jiri; Knox, Tessa; Noonepalle, Satish; Tavares, Mauricio T.; Zimprich, Chad A.; Zhang, Guiping; Robers, Matthew B.; Barinka, Cyril; Kozikowski, Alan P.; Villagra, Alejandro 分享 收藏
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Advancing the Therapeutic Potential of Indoleamides for Tuberculosis Lun, Shichun; Tasneen, Rokeya; Chaira, Tridib; Stec, Jozef; Onajole, Oluseye K.; Yang, Tian J.; Cooper, Christopher B.; Mdluli, Khisi; Converse, Paul J.; Nuermberger, Eric L.; Raj, V. Samuel; Kozikowski, Alan; Bishai, William R. 分享 收藏
Priming the tumor microenvironment with epigenetic modifiers to overcome resistance to immune checkpoint inhibitors Knox, Tessa J.; Sahakian, Eva; Banik, Debarati; Hadley, Melissa; Palmer, Erica; Kim, Jennifer; Noonepalle, Satish; Powers, John; Gracia-Hernandez, Maria; Oliveira, Vasco; Cheng, Fengdong; Chen, Jie; Barinka, Cyril; Pinilla-Ibarz, Javier; Lee, Norman; Kozikowski, Alan; Villagra, Alejandro 分享 收藏
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