Rima Rozen - Publications, H-index & Citations

Rima Rozen

university of zurich

56H指数

171论文数

1.2W被引数

收录论文 54

发表时间

Sperm DNA methylation defects in a new mouse model of the 5,10-methylenetetrahydrofolate reductase 677C>T variant and correction with moderate dose folic acid supplementation

MOLECULAR HUMAN REPRODUCTION

IF3.5

2024-02-16

OAAI

Rebolledo, Edgar Martinez Duncker; Chan, Donovan; Christensen, Karen E.; Reagan, Alaina M.; Howell, Gareth R.; Rozen, Rima; Trasler, Jacquetta

The 677C > T variant in methylenetetrahydrofolate reductase causes morphological and functional cerebrovascular deficits in mice

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

IF4.5

2022-09-01

OAAI

Reagan, Alaina M.; Christensen, Karen E.; Graham, Leah C.; Bedwell, Amanda A.; Eldridge, Kierra; Speedy, Rachael; Figueiredo, Lucas L.; Persohn, Scott C.; Bottiglieri, Teodoro; Nho, Kwangsik; Sasner, Michael; Territo, Paul R.; Rozen, Rima; Howell, Gareth R.

Shifting landscapes of human MTHFR missense-variant effects

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2021-07-01

OAAI

Weile, Jochen; Kishore, Nishka; Sun, Song; Maaieh, Ranim; Verby, Marta; Li, Roujia; Fotiadou, Iosifina; Kitaygorodsky, Julia; Wu, Yingzhou; Holenstein, Alexander; Buerer, Celine; Blomgren, Linnea; Yang, Shan; Nussbaum, Robert; Rozen, Rima; Watkins, David; Gebbia, Marinella; Kozich, Viktor; Garton, Michael; Froese, D. Sean; Roth, Frederick P.

High folic acid intake increases methylation-dependent expression of Lsr and dysregulates hepatic cholesterol homeostasis

JOURNAL OF NUTRITIONAL BIOCHEMISTRY

IF4.9

2021-02-01

PREAI

Leclerc, Daniel; Jelinek, Jaroslav; Christensen, Karen E.; Issa, Jean-Pierre J.; Rozen, Rima

Moderate Folic Acid Supplementation in Pregnant Mice Results in Behavioral Alterations in Offspring with Sex-Specific Changes in Methyl Metabolism

NUTRIENTS

IF5

2020-06-08

OAAI

Cosin-Tomas, Marta; Luan, Yan; Leclerc, Daniel; Malysheva, Olga, V; Lauzon, Nidia; Bahous, Renata H.; Christensen, Karen E.; Caudill, Marie A.; Rozen, Rima

Low Dietary Folate Interacts with MTHFD1 Synthetase Deficiency in Mice, a Model for the R653Q Variant, to Increase Incidence of Developmental Delays and Defects

JOURNAL OF NUTRITION

IF3.8

2018-04-01

OAAI

Christensen, Karen E.; Bahous, Renata H.; Hou, Wenyang; Deng, Liyuan; Malysheva, Olga V.; Arning, Erland; Bottiglieri, Teodoro; Caudill, Marie A.; Jerome-Majewska, Loydie A.; Rozen, Rima

Oncogenic role of PDK4 in human colon cancer cells

BRITISH JOURNAL OF CANCER

IF6.8

2017-02-16

OAAI

Leclerc, D.; Pham, D. N. T.; Levesque, N.; Truongcao, M.; Foulkes, W. D.; Sapienza, C.; Rozen, R.

High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring

HUMAN MOLECULAR GENETICS

IF3.2

2017-01-09

OAAI

Bahous, Renata H.; Jadavji, Nafisa M.; Deng, Liyuan; Cosin-Tomas, Marta; Lu, Jessica; Malysheva, Olga; Leung, Kit-Yi; Ho, Ming-Kai; Pallas, Merce; Kaliman, Perla; Greene, Nicholas D. E.; Bedell, Barry J.; Caudill, Marie A.; Rozen, Rima

Murine MTHFD1-Synthetase Deficiency, a Model for the Human MTHFD1 R653Q Polymorphism, Decreases Growth of Colorectal Tumors 鼠MTHFD1-Synthetase缺乏症是人类MTHFD1 R653Q多态性的模型，可降低结直肠肿瘤的生长

MOLECULAR CARCINOGENESIS

IF3.2

2016-11-01

PREAI

Levesque, Nancy; Christensen, Karen E.; Van der Kraak, Lauren; Best, Ana F.; Deng, Liyuan; Caldwell, Don; MacFarlane, Amanda J.; Beauchemin, Nicole; Rozen, Rima

Moderate folic acid supplementation and MTHFD1-synthetase deficiency in mice, a model for the R653Q variant, result in embryonic defects and abnormal placental development

AMERICAN JOURNAL OF CLINICAL NUTRITION

IF6.9

2016-11-01

OAAI

Christensen, Karen E.; Hou, Wenyang; Bahous, Renata H.; Deng, Liyuan; Malysheva, Olga V.; Arning, Erland; Bottiglieri, Teodom; Caudill, Marie A.; Jerome-Majewska, Loydie A.; Rozen, Rima

Mthfr as a modifier of the retinal phenotype of Crb1rd8/rd8 mice

EXPERIMENTAL EYE RESEARCH

IF2.7

2016-04-01

OAAI

Markand, Shanu; Saul, Alan; Tawfik, Amany; Cui, Xuezhi; Rozen, Rima; Smith, Sylvia B.

High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice

AMERICAN JOURNAL OF CLINICAL NUTRITION

IF6.9

2015-03-01

136

OAAI

Christensen, Karen E.; Mikael, Leonie G.; Leung, Kit-Yi; Levesque, Nancy; Deng, Liyuan; Wu, Qing; Malysheva, Olga V.; Best, Ana; Caudill, Marie A.; Greene, Nicholas D. E.; Rozen, Rima

Quantitative proteomics reveals differentially expressed proteins in murine preneoplastic intestine in a model of intestinal tumorigenesis induced by low dietary folate and MTHFR deficiency

PROTEOMICS

IF3.9

2014-09-05

PREAI

Leclerc, Daniel; Dejgaard, Kurt; Mazur, Alexander; Deng, Liyuan; Wu, Qing; Nilsson, Tommy; Rozen, Rima

Increased Resistance to Malaria in Mice with Methylenetetrahydrofolate Reductase (Mthfr) Deficiency Suggests a Mechanism for Selection of the MTHFR 677C> T (c.665C> T) Variant

HUMAN MUTATION

IF3.7

2014-03-31

OAAI

Meadows, Danielle N.; Pyzik, Michal; Wu, Qing; Torre, Sabrina; Gros, Philippe; Vidal, Silvia M.; Rozen, Rima

The MTHFD1 1958G>A variant is associated with elevated C-reactive protein and body mass index in Canadian women from a premature birth cohort

MOLECULAR GENETICS AND METABOLISM

IF3.5

2014-03-01

PREAI

Christensen, Karen E.; Dahhou, Mourad; Kramer, Michael S.; Rozen, Rima

β,β-Carotene 15,15′-monooxygenase and its substrate β-carotene modulate migration and invasion in colorectal carcinoma cells

AMERICAN JOURNAL OF CLINICAL NUTRITION

IF6.9

2013-08-01

OAAI

Diep Ngoc Thi Pham; Leclerc, Daniel; Levesque, Nancy; Deng, Liyuan; Rozen, Rima

A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development

HUMAN MOLECULAR GENETICS

IF3.2

2013-05-23

OAAI

Christensen, K. E.; Deng, L.; Leung, K. Y.; Arning, E.; Bottiglieri, T.; Malysheva, O. V.; Caudill, M. A.; Krupenko, N. I.; Greene, N. D.; Jerome-Majewska, L.; MacKenzie, R. E.; Rozen, R.

Severe methylenetetrahydrofolate reductase deficiency in mice results in behavioral anomalies with morphological and biochemical changes in hippocampus

MOLECULAR GENETICS AND METABOLISM

IF3.5

2012-06-01

PREAI

Jadavji, Nafisa M.; Deng, Liyuan; Leclerc, Daniel; Malysheva, Olga; Bedell, Barry J.; Caudill, Marie A.; Rozen, Rima

Susceptibility to intestinal tumorigenesis in folate-deficient mice may be influenced by variation in one-carbon metabolism and DNA repair

JOURNAL OF NUTRITIONAL BIOCHEMISTRY

IF4.9

2011-11-01

PREAI

Knock, Erin; Deng, Liyuan; Krupenko, Natalia; Mohan, Ryan D.; Wu, Qing; Leclerc, Daniel; Gupta, Sapna; Elmore, C. Lee; Kruger, Warren; Tini, Marc; Rozen, Rima

Strain-Specific Defects in Testicular Development and Sperm Epigenetic Patterns in 5,10-Methylenetetrahydrofolate Reductase-Deficient Mice

ENDOCRINOLOGY

IF3.3

2010-05-05

OAAI

Chan, Donovan; Cushnie, Duncan W.; Neaga, Oana R.; Lawrance, Andrea K.; Rozen, Rima; Trasler, Jacquetta M.

研究方向