Stuart Aitken - Publications, H-index & Citations

Stuart Aitken

University of Edinburgh

47H指数

270论文数

9.4K被引数

收录论文 29

发表时间

Genetic background sets the trajectory of experimental cancer evolution 遗传背景决定了实验性癌症进化的轨迹

Nature

IF48.5

2026-07-22

OAAI

Sarah J. Aitken; Frances Connor; Christine Feig; Tim F. Rayner; Margus Lukk; Juliet Luft; Stuart Aitken; Claudia Arnedo-Pac; James F. Hayes; Michael D. Nicholson; Ailith Ewing; Vasavi Sundaram; Jan C. Verburg; John Connelly; Craig J. Anderson; Mikaela Behm; Susan Campbell; Maëlle Daunesse; Vera B. Kaiser; Elissavet Kentepozidou; Oriol Pich; Aisling M. Redmond; Javier Santoyo-Lopez; Inés Sentís; Lana Talmane; Paul Flicek; Núria López-Bigas; Colin A. Semple; Martin S. Taylor; Duncan T. Odom

The V-ATPase complex component RNAseK is required for lysosomal hydrolase delivery and autophagosome degradation

NATURE COMMUNICATIONS

IF15.7

2024-09-05

OAAI

Makar, Agata N.; Boraman, Alina; Mosen, Peter; Simpson, Joanne E.; Marques, Jair; Michelberger, Tim; Aitken, Stuart; Wheeler, Ann P.; Winter, Dominic; von Kriegsheim, Alex; Gammoh, Noor

Genomic Diagnosis of Rare Pediatric Disease in the United Kingdom and Ireland 英国和爱尔兰罕见儿科疾病的基因组诊断

NEW ENGLAND JOURNAL OF MEDICINE

IF78.5

2023-04-27

OAAI

Wright, Caroline F.; Campbell, Patrick; Eberhardt, Ruth Y.; Aitken, Stuart; Perrett, Daniel; Brent, Simon; Danecek, Petr; Gardner, Eugene J.; Chundru, V. Kartik; Lindsay, Sarah J.; Andrews, Katrina; Hampstead, Juliet; Kaplanis, Joanna; Samocha, Kaitlin E.; Middleton, Anna; Foreman, Julia; Hobson, Rachel J.; Parker, Michael J.; Martin, Hilary C.; FitzPatrick, David R.; Hurles, Matthew E.; Firth, Helen V.

IMPROVE-DD: Integrating multiple phenotype resources optimizes variant evaluation in genetically determined developmental disorders

HUMAN GENETICS AND GENOMICS ADVANCES

IF3.6

2023-01-01

OAAI

Aitken, Stuart; Firth, Helen, V; Wright, Caroline F.; Hurles, Matthew E.; FitzPatrick, David R.; Semple, Colin A.

A dual role for the RNA helicase DHX34 in NMD and pre-mRNA splicing and its function in hematopoietic differentiation RNA解旋酶DHX34在NMD和pre-mrna剪接中的双重作用及其在造血分化中的功能

RNA

IF5

2022-06-29

OAAI

Hug, Nele; Aitken, Stuart; Longman, Dasa; Raab, Michaela; Armes, Hannah; Mann, Abigail R.; Rio-Machin, Ana; Fitzgibbon, Jude; Rouault-Pierre, Kevin; Caceres, Javier F.

RNA splicing is a key mediator of tumour cell plasticity and a therapeutic vulnerability in colorectal cancer

NATURE COMMUNICATIONS

IF15.7

2022-05-19

OAAI

Hall, Adam E.; Pohl, Sebastian Other-Gee; Cammareri, Patrizia; Aitken, Stuart; Younger, Nicholas T.; Raponi, Michela; Billard, Caroline V.; Carrancio, Alfonso Bolado; Bastem, Aslihan; Freile, Paz; Haward, Fiona; Adams, Ian R.; Caceres, Javier F.; Preyzner, Paula; von Kriegsheim, Alex; Dunlop, Malcolm G.; Din, Farhat V.; Myant, Kevin B.

Nucleo-cytoplasmic shuttling of splicing factor SRSF1 is required for development and cilia function 发育和纤毛功能需要剪接因子SRSF1的核质穿梭

ELIFE

IF0

2021-08-02

OAAI

Haward, Fiona; Maslon, Magdalena M.; Yeyati, Patricia L.; Bellora, Nicolas; Hansen, Jan N.; Aitken, Stuart; Lawson, Jennifer; von Kriegsheim, Alex; Wachten, Dagmar; Mill, Pleasantine; Adams, Ian R.; Caceres, Javier F.

RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways

NATURE COMMUNICATIONS

IF15.7

2021-04-20

OAAI

Gudino, Victoria; Pohl, Sebastian Other-Gee; Billard, Caroline V.; Cammareri, Patrizia; Bolado, Alfonso; Aitken, Stuart; Stevenson, David; Hall, Adam E.; Agostino, Mark; Cassidy, John; Nixon, Colin; von Kriegsheim, Alex; Freile, Paz; Popplewell, Linda; Dickson, George; Murphy, Laura; Wheeler, Ann; Dunlop, Malcolm; Din, Farhat; Strathdee, Douglas; Sansom, Owen J.; Myant, Kevin B.

Finding Diagnostically Useful Patterns in Quantitative Phenotypic Data

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2019-11-01

OAAI

Aitken, Stuart; Firth, Helen V.; McRae, Jeremy; Halachev, Mihail; Kini, Usha; Parker, Michael J.; Lees, Melissa M.; Lachlan, Katherine; Sarkar, Ajoy; Joss, Shelagh; Splitt, Miranda; McKee, Shane; Nemeth, Andrea H.; Scott, Richard H.; Wright, Caroline F.; Marsh, Joseph A.; Hurles, Matthew E.; FitzPatrick, David R.

Embryonic mesothelial-derived hepatic lineage of quiescent and heterogenous scar-orchestrating cells defined but suppressed by WT1 由WT1定义但被抑制的静止和异质瘢痕协调细胞的胚胎间皮衍生的肝谱系

NATURE COMMUNICATIONS

IF15.7

2019-10-15

OAAI

Kendall, Timothy James; Duff, Catherine Mary; Boulter, Luke; Wilson, David H.; Freyer, Elisabeth; Aitken, Stuart; Forbes, Stuart John; Iredale, John Peter; Hastie, Nicholas Dixon

A slow transcription rate causes embryonic lethality and perturbs kinetic coupling of neuronal genes 缓慢的转录速率导致胚胎致死并干扰神经元基因的动力学耦合

EMBO JOURNAL

IF8.3

2019-04-15

OAAI

Maslon, Magdalena M.; Braunschweig, Ulrich; Aitken, Stuart; Mann, Abigail R.; Kilanowski, Fiona; Hunter, Chris J.; Blencowe, Benjamin J.; Kornblihtt, Alberto R.; Adams, Ian R.; Caceres, Javier F.

Development and Sustainable Ethics in Fanjingshan National Nature Reserve, China

ANNALS OF THE AMERICAN ASSOCIATION OF GEOGRAPHERS

IF2.9

2019-02-01

PREAI

Aitken, Stuart C.; An, Li; Yang, Shuang

Making new genetic diagnoses with old data: iterative reanalysis and reporting from genome-wide data in 1,133 families with developmental disorders 用旧数据进行新的遗传诊断: 1,133个发育障碍家庭的全基因组数据的迭代再分析和报告

GENETICS IN MEDICINE

IF6.2

2018-10-01

235

OAAI

Wright, Caroline F.; McRae, Jeremy F.; Clayton, Stephen; Gallone, Giuseppe; Aitken, Stuart; FitzGerald, Tomas W.; Jones, Philip; Prigmore, Elena; Rajan, Diana; Lord, Jenny; Sifrim, Alejandro; Kelsell, Rosemary; Parker, Michael J.; Barrett, Jeffrey C.; Hurles, Matthew E.; FitzPatrick, David R.; Firth, Helen V.

The circadian dynamics of small nucleolar RNA in the mouse liver

JOURNAL OF THE ROYAL SOCIETY INTERFACE

IF3.5

2017-05-03

OAAI

Aitken, Stuart; Semple, Colin A.

WT1 expression in breast cancer disrupts the epithelial/mesenchymal balance of tumour cells and correlates with the metabolic response to docetaxel 乳腺癌中WT1的表达破坏了肿瘤细胞的上皮/间质平衡，并与多西他赛的代谢反应相关

SCIENTIFIC REPORTS

IF3.9

2017-03-27

OAAI

Artibani, Mara; Sims, Andrew H.; Slight, Joan; Aitken, Stuart; Thornburn, Anna; Muir, Morwenna; Brunton, Valerie G.; Del-Pozo, Jorge; Morrison, Linda R.; Katz, Elad; Hastie, Nicholas D.; Hohenstein, Peter

Locked in Place: Young People's Immobilities and the Slovenian Erasure

ANNALS OF THE AMERICAN ASSOCIATION OF GEOGRAPHERS

IF2.9

2016-01-04

PREAI

Aitken, Stuart C.

Hierarchical folding and reorganization of chromosomes are linked to transcriptional changesin cellular differentiation

MOLECULAR SYSTEMS BIOLOGY

IF7.7

2015-12-28

273

OAAI

Fraser, James; Ferrai, Carmelo; Chiariello, Andrea M.; Schueler, Markus; Rito, Tiago; Laudanno, Giovanni; Barbieri, Mariano; Moore, Benjamin L.; Kraemer, Dorothee C. A.; Aitken, Stuart; Xie, Sheila Q.; Morris, Kelly J.; Itoh, Masayoshi; Kawaji, Hideya; Jaeger, Ines; Hayashizaki, Yoshihide; Carninci, Piero; Forrest, Alistair R. R.; Semple, Colin A.; Dostie, Josee; Pombo, Ana; Nicodemi, Mario

Integrative modeling reveals the principles of multi-scale chromatin boundary formation in human nuclear organization

GENOME BIOLOGY

IF9.4

2015-05-27

OAAI

Moore, Benjamin L.; Aitken, Stuart; Semple, Colin A.

Snapshots of pre-rRNA structural flexibility reveal eukaryotic 40S assembly dynamics at nucleotide resolution

NUCLEIC ACIDS RESEARCH

IF13.1

2014-09-08

OAAI

Hector, Ralph D.; Burlacu, Elena; Aitken, Stuart; Le Bihan, Thierry; Tuijtel, Maarten; Zaplatina, Alina; Cook, Atlanta G.; Granneman, Sander