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Mapping Redox Signaling Events in Early Metastatic Ovarian Cancer Tang, Priscilla; Elhaw, Amal; Cheng, Ya-Yun; Spencer, Connor; Benson, James; Wallace, Callen; St Croix, Claudette; Happe, Cassandra; Gelhaus, Stacy; Held, Jason; Trebak, Mohamed; Cunniff, Brian; Hempel, Nadine 分享 收藏
Drp1 splice variants regulate ovarian cancer mitochondrial dynamics and tumor progression Javed, Zaineb; Shin, Dong Hui; Pan, Weihua; White, Sierra R.; Elhaw, Amal Taher; Kim, Yeon Soo; Kamlapurkar, Shriya; Cheng, Ya-Yun; Benson, J. Cory; Abdelnaby, Ahmed Emam; Phaeton, Rebecca; Wang, Hong-Gang; Yang, Shengyu; Sullivan, Mara L. G.; Croix, Claudette M. St; Watkins, Simon C.; Mullett, Steven J.; Gelhaus, Stacy L.; Lee, Nam; Coffman, Lan G.; Aird, Katherine M.; Trebak, Mohamed; Mythreye, Karthikeyan; Walter, Vonn; Hempel, Nadine 分享 收藏
Carcinoma-associated mesenchymal stem cells promote ovarian cancer heterogeneity and metastasis through mitochondrial transfer Frisbie, Leonard; Pressimone, Catherine; Dyer, Emma; Baruwal, Roja; Garcia, Geyon; St. Croix, Claudette; Watkins, Simon; Calderone, Michael; Gorecki, Grace; Javed, Zaineb; Atiya, Huda I.; Hempel, Nadine; Pearson, Alexander; Coffman, Lan G. 分享 收藏
Compartmentalized mitochondrial ferroptosis converges with optineurin-mediated mitophagy to impact airway epithelial cell phenotypes and asthma outcomes Yamada, Kazuhiro; St. Croix, Claudette; Stolz, Donna B.; Tyurina, Yulia Y.; Tyurin, Vladimir A.; Bradley, Laura R.; Kapralov, Alexander A.; Deng, Yanhan; Zhou, Xiuxia; Wei, Qi; Liao, Bo; Fukuda, Nobuhiko; Sullivan, Mara; Trudeau, John; Ray, Anuradha; Kagan, Valerian E.; Zhao, Jinming; Wenzel, Sally E. 分享 收藏
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Carcinoma-associated mesenchymal stem cells promote high-grade serous ovarian cancer metastasis and drive tumor heterogeneity at the metastatic site through direct mitochondrial transfer Frisbie, Leonard G.; Pressimone, Catherine A.; Baruwal, Roja; Garcia, Geyon L.; Javed, Zanib; St Croix, Claudette; Watkins, Simon; Calderone, Michael; Atiya, Huda I.; Hempel, Nadine; Pearson, Alexander; Coffman, Lan G. 分享 收藏
Strikingly High Activity of 15-Lipoxygenase Towards Di-Polyunsaturated Arachidonoyl/Adrenoyl-Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell Death 15-脂氧合酶对二多不饱和花生四烯酸/肾上腺脂酰磷脂酰乙醇胺的活性非常高，可产生铁性细胞死亡的过氧化信号 Samovich, Svetlana N.; Mikulska-Ruminska, Karolina; Dar, Haider H.; Tyurina, Yulia Y.; Tyurin, Vladimir A.; Souryavong, Austin B.; Kapralov, Alexander A.; Amoscato, Andrew A.; Beharier, Ofer; Karumanchi, S. Ananth; St Croix, Claudette M.; Yang, Xin; Holman, Theodore R.; Vandemark, Andrew P.; Sadovsky, Yoel; Mallampalli, Rama K.; Wenzel, Sally E.; Gu, Wei; Bunimovich, Yuri L.; Bahar, Ivet; Kagan, Valerian E.; Bayir, Huelya 分享 收藏
SIRT3/SOD2/H2O2-mediated redox signaling supports ovarian cancer anchorage-independence Tang, Priscilla; Elhaw, Amal; Benson, James; Wallace, Callen; St Croix, Claudette; Happe, Cassandra; Mullett, Steve; Gelhaus, Stacy; Trebak, Mohamed; Cunniff, Brian; Hempel, Nadine 分享 收藏
Discovering selective antiferroptotic inhibitors of the 15LOX/PEBP1 complex noninterfering with biosynthesis of lipid mediators 发现不干扰脂质介质生物合成的15LOX/PEBP1复合物的选择性抗铁性抑制剂 Dar, Haider H.; Ruminska, Karolina Mikulska-; Tyurina, Yulia Y.; Luci, Diane K.; Yasgar, Adam; Samovich, Svetlana N.; Kapralov, Alexander A.; Souryavong, Austin B.; Tyurin, Vladimir A.; Amoscato, Andrew A.; Epperly, Michael W.; V. Shurin, Galina; Standley, Melissa; Holman, Theodore R.; Croix, Claudette M. St.; Watkins, Simon C.; VanDemark, Andrew P.; Rana, Sandeep; V. Zakharov, Alexey; Simeonov, Anton; Marugan, Juan; Mallampalli, Rama K.; Wenzel, Sally E.; Greenberger, Joel S.; Rai, Ganesha; Bayir, Huelya; Bahar, Ivet; Kagan, Valerian E. 分享 收藏
Reduced mitophagy is an early feature of NAFLD and liver-specific PARKIN knockout hastens the onset of steatosis, inflammation and fibrosis Undamatla, R.; Fagunloye, O. G.; Chen, J.; Edmunds, L. R.; Murali, A.; Mills, A.; Xie, B.; Pangburn, M. M.; Sipula, I.; Gibson, G.; St. Croix, C.; Jurczak, M. J. 分享 收藏
Visualizing Cardiolipin In Situ with HKCL-1M, a Highly Selective and Sensitive Fluorescent Probe Wang, Wei; Wong, Nai-Kei; Bok, Siu-Lun; Xu, You; Guo, Yang; Xu, Lu; Zuo, Meiling; St Croix, Claudette M.; Mao, Gaowei; Kapralov, Alexandr; Bayir, Hulya; Kagan, Valerian E.; Yang, Dan 分享 收藏
Loss of DNA repair mechanisms in cardiac myocytes induce dilated cardiomyopathy Henpita, Chathurika; Vyas, Rajesh; Healy, Chastity L.; Kieu, Tra L.; Gurkar, Aditi U.; Yousefzadeh, Matthew J.; Cui, Yuxiang; Lu, Aiping; Angelini, Luise A.; O'Kelly, Ryan D.; McGowan, Sara J.; Chandrasekhar, Sanjay; Vanderpool, Rebecca R.; Hennessy-Wack, Danielle; Ross, Mark A.; Bachman, Timothy N.; McTiernan, Charles; Pillai, Smitha P. S.; Ladiges, Warren; Lavasani, Mitra; Huard, Johnny; Beer-Stolz, Donna; St. Croix, Claudette M.; Watkins, Simon C.; Robbins, Paul D.; Mora, Ana L.; Kelley, Eric E.; Wang, Yinsheng; O'Connell, Timothy D.; Niedernhofer, Laura J. 分享 收藏
NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health NIH SenNet联盟绘制人类整个生命周期中的衰老细胞以了解生理健康 Lee, Patty J.; Benz, Christopher C.; Blood, Philip; Boerner, Katy; Campisi, Judith; Chen, Feng; Daldrup-Link, Heike; De Jager, Phil; Ding, Li; Duncan, Francesca E.; Eickelberg, Oliver; Fan, Rong; Finkel, Toren; Furman, David; Garovic, Vesna; Gehlenborg, Nils; Glass, Carolyn; Heckenbach, Indra; Joseph, Ziv-Bar; Katiyar, Pragati; Kim, So-Jin; Koenigshoff, Melanie; Kuchel, George A.; Lee, Haesung; Lee, Jun Hee; Ma, Jian; Ma, Qin; Melov, Simon; Metis, Kay; Mora, Ana L.; Musi, Nicolas; Neretti, Nicola; Passos, Joao F.; Rahman, Irfan; Rivera-Mulia, Juan Carlos; Robson, Paul; Rojas, Mauricio; Roy, Ananda L.; Scheibye-Knudsen, Morten; Schilling, Birgit; Shi, Pixu; Silverstein, Jonathan C.; Suryadevara, Vidyani; Xie, Jichun; Wang, Jinhua; Wong, A. Ian; Niedernhofer, Laura J.; Wang, Siyuan (Steven); Anvari, Hannah; Balough, Julia; Benz, Christopher; Bons, Joanna; Brenerman, Boris; Evans, William; Gerencser, Akos; Gregory, Heather; Hansen, Malene; Justice, Jamie; Kapahi, Pankaj; Murad, Natalia; O'Broin, Amy; Pavone, Mary Ellen; Powell, Mark; Scott, Gary; Shanes, Elisheva; Shankaran, Mahalakshmi; Verdin, Eric; Winer, Daniel; Wu, Fei; Adams, Andrew; Blood, Philip D.; Bueckle, Andreas; Cao-Berg, Ivan; Chen, Hao; Davis, Michael; Filus, Shane; Hao, Yuhan; Hartman, Austin; Hasanaj, Euxhen; Helfer, Jesse; Herr, Bruce, II; Bar Joseph, Ziv; Molla, Gesmira; Mou, Gloria; Puerto, Juan; Quardokus, Ellen M.; Ropelewski, Alexander J.; Ruffalo, Matt; Satija, Rahul; Schwenk, Melissa; Scibek, Robin; Shirey, William; Sibilla, Max; Welling, Joel; Yuan, Zhou; Bonneau, Richard; Christiano, Angela; Izar, Benjamin; Menon, Vilas; Owens, David M.; Phatnani, Hemali; Smith, Colin; Suh, Yousin; Teich, Andrew F.; Bekker, Valerie; Chan, Cliburn; Coutavas, Elias; Hartwig, Matthew G.; Ji, Zhicheng; Nixon, Andrew B.; Dou, Zhixun; Rajagopal, Jayaraj; Slavov, Nikolai; Holmes, David, III; Jurk, Diana; Kirkland, James L.; Lagnado, Anthony; Tchkonia, Tamara; Abraham, Kristin; Dibattista, Amanda; Fridell, Yih-Woei; Howcroft, T. Kevin; Jhappan, Chamelli; Montes, Viviana Perez; Prabhudas, Mercy; Resat, Haluk; Taylor, Veronica; Kumar, Manoj; Cigarroa, Francisco; Cohn, Rachel; Cortes, Tiffany M.; Courtois, Elise; Chuang, Jeffrey; Dave, Monica; Domanskyi, Sergii; Enninga, Elizabeth Ann Lieser; Eryilmaz, Giray Naim; Espinoza, Sara E.; Gelfond, Jon; Kirkland, James; Kuo, Chia-Ling; Lehman, Julia S.; Aguayo-Mazzucato, Cristina; Meves, Alexander; Rani, Meenakshi; Sanders, Shane; Thibodeau, Asa; Tullius, Stefan G.; Ucar, Duygu; White, Brian; Wu, Qian; Xu, Ming; Yamaguchi, Seiji; Assarzadegan, Naziheh; Cho, Chun-Seok; Hwang, Irene; Hwang, Yongha; Xi, Jingyue; Adeyi, Oyedele A.; Aliferis, Constantin F.; Bartolomucci, Alessandro; Dong, Xiao; DuFresne-To, Mickayla J.; Ikramuddin, Sayeed; Johnson, Steve G.; Nelson, Andrew C.; Revelo, Xavier S.; Trevilla-Garcia, Claudia; Sedivy, John M.; Thompson, Elizabeth L.; Robbins, Paul D.; Wang, Jinhua; Aird, Katherine M.; Alder, Jonathan K.; Beaulieu, Delphine; Bueno, Marta; Calyeca, Jazmin; Chamucero-Millaris, Julian A.; Chan, Stephen Y.; Chung, Dongjun; Corbett, Anthony; Gorbunova, Vera; Gowdy, Kymberly M.; Gurkar, Aditi; Horowitz, Jeffrey C.; Hu, Qianjiang; Kaur, Gagandeep; Khaliullin, Timur O.; Lafyatis, Robert; Lanna, Serafina; Li, Dongmei; Ma, Anjun; Morris, Alison; Muthumalage, Thivanka M.; Peters, Victor; Pryhuber, Gloria S.; Reader, Brenda F.; Rosas, Lorena; Sembrat, John C.; Shaikh, Sadiya; Shi, Hangchuan; Stacey, Sean D.; St Croix, Claudette; Wang, Cankun; Wang, Qixin; Watts, Andrew; Gu, Liangcai; Lin, Yiing; Rabinovitch, Peter S.; Sweetwyne, Mariya T.; Artyomov, Maxim N.; Ballentine, Samuel J.; Chheda, Milan G.; Davies, Sherri R.; DiPersio, John F.; Fields, Ryan C.; Fitzpatrick, James A. J.; Fulton, Robert S.; Imai, Shin-ichiro; Jain, Sanjay; Ju, Tao; Kushnir, Vladimir M.; Link, Daniel C.; Ben Major, Michael; Oh, Stephen T.; Rapp, Daniel; Rettig, Michael P.; Stewart, Shelia A.; Veis, Deborah J.; Vij, Kiran R.; Wendl, Michael C.; Wyczalkowski, Matthew A.; Craft, Joseph E.; Enninful, Archibald; Farzad, Negin; Gershkovich, Peter; Halene, Stephanie; Kluger, Yuval; VanOudenhove, Jennifer; Xu, Mina; Yang, Junchen; Yang, Mingyu 分享 收藏
Resuscitation with epinephrine worsens cerebral capillary no-reflow after experimental pediatric cardiac arrest: An in vivo multiphoton microscopy evaluation Oghifobibi, Onome A.; Toader, Andrew E.; Nicholas, Melissa A.; Nelson, Brittany P.; Alindogan, Nicole G.; Wolf, Michael S.; Kline, Anthony E.; Nouraie, Seyed M.; Bondi, Corina O.; Iordanova, Bistra; Clark, Robert S. B.; Bayir, Hulya; Loughran, Patricia A.; Watkins, Simon C.; St Croix, Claudette M.; Kochanek, Patrick M.; Vazquez, Alberto L.; Manole, Mioara D. 分享 收藏
Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD 在干性AMD小鼠模型中，RPE中LCN2 (脂质运载蛋白2) 的增加会降低自噬并激活炎症小体-铁死亡过程 Gupta, Urvi; Ghosh, Sayan; Wallace, Callen T.; Shang, Peng; Xin, Ying; Nair, Archana Padmanabhan; Yazdankhah, Meysam; Strizhakova, Anastasia; Ross, Mark A.; Liu, Haitao; Hose, Stacey; Stepicheva, Nadezda A.; Chowdhury, Olivia; Nemani, Mihir; Maddipatla, Vishnu; Grebe, Rhonda; Das, Manjula; Lathrop, Kira L.; Sahel, Jose-Alain; Zigler, J. Samuel, Jr.; Qian, Jiang; Ghosh, Arkasubhra; Sergeev, Yuri; Handa, James T.; St Croix, Claudette M.; Sinha, Debasish 分享 收藏
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