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D

David Schubert

novartis biomedical research

80H指数
241论文数
2.4W被引数
收录论文 70
发表时间
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IL-2 mutein-engrafted antibody MHS552 selectively expands functional regulatory T cells in nonclinical models and healthy participantsIL-2 mutein-engrafted抗体MHS552在非临床模型和健康受试者中选择性扩增功能性调节性T细胞
errNature Communications
IF15.7
err2026-08-12
err0
errOAAI
errIgor Radanović; Michael DiDonato; Anouk C. Meijs; David A. Schubert; Yaiza Diaz-de-Durana; Andrea Kiessling; Thierry Flandre; Hannah Morgan; Claudia Simonett; Justin McMullen; Manon AA. Jansen; Thomas P. Buters; Mahdi Saghari; Pim Gal; Jacobus J. Bosch; Sjoerd H. van der Burg; Susanne Osanto; Morten Bagger; Claudio Calonder; Darbi Witmer; Ulrike Sommer; Frank Waldron-Lynch; Peter Gergely; Nadege Pelletier; Nicole Hartmann; Esther Kamphausen; Magdalena Kistowska; Helene Marsot; Anita Auger-Sarrazin; Celine Rauld; Camille Regairaz; Timothy Tree; Yann Ladner; Naomi B. Klarenbeek; Matthijs Moerland; Robert Rissmann; Glen Spraggon; Leona Gabryšová
err分享
err收藏
Translocating gut pathobiont Enterococcus gallinarum induces TH17 and IgG3 anti-RNA-directed autoimmunity in mouse and human跨膜转运肠道病原体共生菌 Enterococcus gallinarum 可诱导小鼠和人类产生 TH17 和 IgG3 抗 RNA 驱动的自身免疫。
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2025-02-05
err0
PREAI
errGronke, Konrad; Nguyen, Mytien; Fuhrmann, Helen; de Souza, Noemi Santamaria; Schumacher, Julia; Pereira, Marcia S.; Loeschberger, Ulrike; Brinkhege, Anna; Becker, Nathalie J.; Yang, Yi; Sonnert, Nicole; Leopold, Shana; Martin, Anjelica L.; von Muenchow-Klein, Lilly; Rodrigues, Cecilia Pessoa; Cansever, Dilay; Hallet, Remy; Richter, Kirsten; Schubert, David A.; Daniel, Guillaume M.; Dylus, David; Forkel, Marianne; Schwinge, Dorothee; Schramm, Christoph; Redanz, Sylvio; Lassen, Kara G.; Vieira, Silvio Manfredo; Piali, Luca; Palm, Noah W.; Bieniossek, Christoph; Kriegel, Martin A.
err分享
err收藏
Transcriptional profiling upon T cell stimulation reveals down-regulation of inflammatory pathways in T and B cells in SLE versus Sjögren's syndrome
errNPJ SYSTEMS BIOLOGY AND APPLICATIONS
IF3.5
err2023-12-15
err1
errOAAI
errKwon, Gino; Wiedemann, Annika; Steinheuer, Lisa M.; Stefanski, Ana-Luisa; Szelinski, Franziska; Racek, Tomas; Frei, Andreas Philipp; Hatje, Klas; Kam-Thong, Tony; Schubert, David; Schindler, Thomas; Dorner, Thomas; Thurley, Kevin
err分享
err收藏
Costimulation blockade in combination with IL-2 permits regulatory T cell sparing immunomodulation that inhibits autoimmunity (vol 13, 6757, 2022)
errNATURE COMMUNICATIONS
IF15.7
err2023-09-15
err0
errOAAI
errWang, Chun Jing; Petersone, Lina; Edner, Natalie M.; Heuts, Frank; Ovcinnikovs, Vitalijs; Ntavli, Elisavet; Kogimtzis, Alexandros; Fabri, Astrid; Elfaki, Yassin; Houghton, Luke P.; Hosse, Ralf J.; Schubert, David A.; Frei, Andreas P.; Ross, Ellen M.; Walker, Lucy S. K.
err分享
err收藏
Costimulation blockade in combination with IL-2 permits regulatory T cell sparing immunomodulation that inhibits autoimmunity
errNATURE COMMUNICATIONS
IF15.7
err2022-11-09
err14
errOAAI
errWang, Chun Jing; Petersone, Lina; Edner, Natalie M.; Heuts, Frank; Ovcinnikovs, Vitalijs; Ntavli, Elisavet; Kogimtzis, Alexandros; Fabri, Astrid; Elfaki, Yassin; Houghton, Luke P.; Hosse, Ralf J.; Schubert, David A.; Frei, Andreas P.; Ross, Ellen M.; Walker, Lucy S. K.
err分享
err收藏
Cannabinol inhibits oxytosis/ferroptosis by directly targeting mitochondria independently of cannabinoid receptors (vol 180, pg 33, 2020)
errFREE RADICAL BIOLOGY AND MEDICINE
IF8.2
err2022-05-01
err1
errOAAI
errLiang, Zhibin; Soriano-Castell, David; Kepchia, Devin; Duggan, Brendan M.; Currais, Antonio; Schubert, David; Maher, Pamela
err分享
err收藏
Cannabinol inhibits oxytosis/ferroptosis by directly targeting mitochondria independently of cannabinoid receptors
errFREE RADICAL BIOLOGY AND MEDICINE
IF8.2
err2022-02-01
err25
errOAAI
errLiang, Zhibin; Soriano-Castell, David; Kepchia, Devin; Duggan, Brendan M.; Currais, Antonio; Schubert, David; Maher, Pamela
err分享
err收藏
Natural products targeting mitochondria: emerging therapeutics for age-associated neurological disorders靶向线粒体的天然产物: 与年龄相关的神经系统疾病的新兴疗法
errPHARMACOLOGY & THERAPEUTICS
IF12.5
err2021-05-01
err43
errOAAI
errLiang, Zhibin; Currais, Antonio; Soriano-Castell, David; Schubert, David; Maher, Pamela
err分享
err收藏
Using the Oxytosis/Ferroptosis Pathway to Understand and Treat Age-Associated Neurodegenerative Diseases
errCELL CHEMICAL BIOLOGY
IF7.2
err2020-12-01
err72
errOAAI
errMaher, Pamela; Currais, Antonio; Schubert, David
err分享
err收藏
Intracellular amyloid toxicity induces oxytosis/ferroptosis regulated cell death
errCELL DEATH & DISEASE
IF9.6
err2020-10-06
err88
errOAAI
errHuang, Ling; McClatchy, Daniel B.; Maher, Pamela; Liang, Zhibin; Diedrich, Jolene K.; Soriano-Castell, David; Goldberg, Joshua; Shokhirev, Maxim; Yates, John R.; Schubert, David; Currais, Antonio
err分享
err收藏
Targeting of intracellular Ca2+ stores as a therapeutic strategy against age-related neurotoxicities
errNPJ AGING AND MECHANISMS OF DISEASE
IF5.4
err2020-08-24
err25
errOAAI
errGoldberg, Joshua; Currais, Antonio; Ates, Gamze; Huang, Ling; Shokhirev, Maxim; Maher, Pamela; Schubert, David
err分享
err收藏
A chemical biology approach to identifying molecular pathways associated with aging识别与衰老相关的分子途径的化学生物学方法
errGEROSCIENCE
IF5.4
err2020-07-23
err7
errOAAI
errCurrais, Antonio; Huang, Ling; Petrascheck, Michael; Maher, Pamela; Schubert, David
err分享
err收藏
Diverse proteins aggregate in mild cognitive impairment and Alzheimer's disease brain
errALZHEIMERS RESEARCH & THERAPY
IF7.6
err2020-06-19
err34
errOAAI
errKepchia, Devin; Huang, Ling; Dargusch, Richard; Rissman, Robert A.; Shokhirev, Maxim N.; Fischer, Wolfgang; Schubert, David
err分享
err收藏
Elevating acetyl-CoA levels reduces aspects of brain aging
errELIFE
IF0
err2019-11-19
err99
errOAAI
errCurrais, Antonio; Huang, Ling; Goldberg, Joshua; Petrascheck, Michael; Ates, Gamze; Pinto-Duarte, Antonio; Shokhirev, Maxim N.; Schubert, David; Maher, Pamela
err分享
err收藏
Geroneuroprotectors: Effective Geroprotectors for the Brain
errTRENDS IN PHARMACOLOGICAL SCIENCES
IF19.9
err2018-12-01
err35
errOAAI
errSchubert, David; Currais, Antonio; Goldberg, Joshua; Finley, Kim; Petrascheck, Michael; Maher, Pamela
err分享
err收藏
Several targets involved in Alzheimer's disease amyloidogenesis are affected by morin and isoquercitrin
errNUTRITIONAL NEUROSCIENCE
IF3.6
err2018-10-16
err42
PREAI
errCarmona, Vanesa; Martin-Aragon, Sagrario; Goldberg, Joshua; Schubert, David; Bermejo-Bescos, Paloma
err分享
err收藏
Tissue-Specific Immunoregulation: A Call for Better Understanding of the Immunostat in the Context of Cancer组织特异性免疫调节: 呼吁在癌症背景下更好地理解免疫状态
errCANCER DISCOVERY
IF33.3
err2018-04-01
err73
PREAI
errPao, William; Ooi, Chia-Huey; Birzele, Fabian; Ruefli-Brasse, Astrid; Cannarile, Michael A.; Reis, Bernhard; Scharf, Sebastian H.; Schubert, David A.; Hatje, Klas; Pelletier, Nadege; Spleiss, Olivia; Reed, John C.
err分享
err收藏
The mitochondrial ATP synthase is a shared drug target for aging and dementia
errAGING CELL
IF7.1
err2018-01-07
err117
errOAAI
errGoldberg, Joshua; Currais, Antonio; Prior, Marguerite; Fischer, Wolfgang; Chiruta, Chandramouli; Ratliff, Eric; Daugherty, Daniel; Dargusch, Richard; Finley, Kim; Esparza-Molto, Pau B.; Cuezva, Jose M.; Maher, Pamela; Petrascheck, Michael; Schubert, David
err分享
err收藏
A novel Alzheimer's disease drug candidate targeting inflammation and fatty acid metabolism
errALZHEIMERS RESEARCH & THERAPY
IF7.6
err2017-07-14
err41
errOAAI
errDaugherty, Daniel; Goldberg, Joshua; Fischer, Wolfgang; Dargusch, Richard; Maher, Pamela; Schubert, David
err分享
err收藏
Fisetin Reduces the Impact of Aging on Behavior and Physiology in the Rapidly Aging SAMP8 Mouse
errJOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
IF3.8
err2017-06-02
err102
errOAAI
errCurrais, Antonio; Farrokhi, Catherine; Dargusch, Richard; Armando, Aaron; Quehenberger, Oswald; Schubert, David; Maher, Pamela
err分享
err收藏

研究方向

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