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收藏分享 收藏 Identification and Biological Evaluation of a Novel CLK4 Inhibitor Targeting Alternative Splicing in Pancreatic Cancer Using Structure-Based Virtual Screening基于结构虚拟筛选的胰腺癌选择性剪接靶向新型CLK4抑制剂的鉴定与生物活性评价
Yang, CL; Wu, YW; Tu, HJ; Yeh, YH; Lin, TE; Sung, TY; Li, MC; Yen, SC; Hsieh, JH; Yu, MC; Hsieh, SY; Hsieh, HP; Pan, SL; Hsu, KC 分享 收藏 Novel Naphthyridones Targeting Pannexin 1 for Colitis Management新型萘啶酮靶向连接蛋白1用于结肠炎管理Hsueh, WY; Wu, YL; Weng, MT; Liu, SY; Santavanond, JP; Liu, YC; Lin, C; Lai, CN; Lu, YR; Hsu, JY; Gao, HY; Lee, JC; Wei, SC; Lyu, PC; Poon, IKH; Hsieh, HP; Chiu, YH 分享 收藏 Discovery of novel TANK-Binding Kinase 1 (TBK1) inhibitor against pancreatic ductal adenocarcinoma新型TANK结合激酶1 (TBK1) 抑制剂抗胰腺导管腺癌的发现Shih, Wan-Hsi; Huang, Han-Li; Huangfu, Wei-Chun; Lin, Tony Eight; Sung, Tzu-Ying; Li, Mu-Chun; Huang, Guan-Lin; Chang, Yu-Wei; Yen, Shih-Chung; Hsieh, Hsing-Pang; Hsu, Kai-Cheng; Pan, Shiow-Lin 分享 收藏 DBPR116, a Prodrug of BPRMU191, in Combination with Naltrexone as a Safer Opioid Analgesic Than Morphine via Peripheral AdministrationLin, Shu-Yu; Chang, Yung-Chiao; Tien, Ya-Wen; Kuo, Yu-Hsien; Chang, Hsiao-Fu; Ou, Li-Chin; Chen, Ya-Ping; Chang, Kuei-Hua; Hsu, Ying-Ting; Huang, Yu-Chen; Yang, Chen-Ming; Law, Ping-Yee; Xi, Jing-Hua; Tao, Pao-Luh; Loh, Horace H.; Yeh, Teng-Kuang; Zhuang, Hong; Hsieh, Hsing-Pang; Shih, Chuan; Chen, Chiung-Tong; Yeh, Shiu-Hwa; Ueng, Shau-Hua 分享 收藏 Discovery of Dual MER/AXL Kinase Inhibitors as Bifunctional Small Molecules for Inhibiting Tumor Growth and Enhancing Tumor Immune MicroenvironmentLi, Mu-Chun; Lai, You-Liang; Kuo, Po-Hsien; Reddy, Julakanti Satyanarayana; Chen, Chih-Ming; Manimala, Julakanti; Wang, Pei-Chen; Wu, Ming-Shiem; Chang, Chun-Yu; Yang, Chen-Ming; Lin, Chin-Yu; Huang, Yu-Chen; Chiu, Chun-Hsien; Chang, Ling; Lin, Wen-Hsing; Yeh, Teng-Kuang; Yen, Wan-Ching; Hsieh, Hsing-Pang 分享 收藏 Macrophage-mediated controlled release of cysteine protease inhibitor from PLGA-PEG/hydroxyapatite microspheres for targeting cathepsin S in Alzheimer's diseaseYang, I-Hsuan; Kuan, Che-Yung; Zhang, Sheng-Long; Chen, Zhi-Yu; Li, Chi-Han; Liang, Ya-Jyun; Kuo, Wei-Ting; Chang, Chia-Ting; Lin, Jason; Hsieh, Hsing-Pang; Chang, Jang-Yang; Lin, Feng-Huei 分享 收藏 Targeting cathepsin S promotes activation of OLF1-BDNF/TrkB axis to enhance cognitive functionLee, Hao-Wei; Chen, Szu-Jung; Tsai, Kuen-Jer; Hsu, Kuei-Sen; Chen, Yi-Fan; Chang, Chih-Hua; Lin, Hsiao-Han; Hsueh, Wen-Yun; Hsieh, Hsing-Pang; Lee, Yueh-Feng; Chiang, Huai-Chueh; Chang, Jang-Yang 分享 收藏 分享 收藏 分享 收藏 A dual nociceptin and mu opioid receptor agonist exhibited robust antinociceptive effect with decreased side effectsHsu, Ying-Ting; Chen, Shen-Ren; Chang, Yung-Chiao; Chang, Hsiao-Fu; Yeh, Teng-Kuang; Chuang, Jian-Ying; Loh, Horace H.; Hsieh, Hsing-Pang; Ueng, Shau-Hua; Yeh, Shiu-Hwa 分享 收藏 分享 收藏 Development of Furanopyrimidine-Based Orally Active Third- Generation EGFR Inhibitors for the Treatment of Non-Small Cell Lung CancerLi, Mu -Chun; Coumar, Mohane Selvaraj; Lin, Shu-Yu; Lin, Yih-Shyan; Huang, Guan-Lin; Chen, Chun-Hwa; Lien, Tzu-Wen; Wu, Yi-Wen; Chen, Yen-Ting; Chen, Ching-Ping; Huang, Yu-Chen; Yeh, Kai-Chia; Yang, Chen -Ming; Kalita, Bikashita; Pan, Shiow-Lin; Hsu, Tsu-An; Yeh, Teng-Kuang; Chen, Chiung-Tong; Hsieh, Hsing-Pang 分享 收藏 A critical overview of current progress for COVID-19: development of vaccines, antiviral drugs, and therapeutic antibodies当前新型冠状病毒肺炎进展的重要概述: 疫苗，抗病毒药物和治疗性抗体的开发Kumari, Monika; Lu, Ruei-Min; Li, Mu-Chun; Huang, Jhih-Liang; Hsu, Fu-Fei; Ko, Shih-Han; Ke, Feng-Yi; Su, Shih-Chieh; Liang, Kang-Hao; Yuan, Joyce Pei-Yi; Chiang, Hsiao-Ling; Sun, Cheng-Pu; Lee, I-Jung; Li, Wen-Shan; Hsieh, Hsing-Pang; Tao, Mi-Hua; Wu, Han-Chung 分享 收藏 Natural product myricetin is a pan-KDM4 inhibitor which with poly lactic-co-glycolic acid formulation effectively targets castration-resistant prostate cancerLiu, Jai-Shin; Fang, Wei-Kai; Yang, Shan-Min; Wu, Meng-Chen; Chen, Tsan-Jan; Chen, Chih-Ming; Lin, Tung-Yueh; Liu, Kai-Lun; Wu, Chien-Ming; Chen, Yun-Ching; Chuu, Chih-Pin; Wang, Ling-Yu; Hsieh, Hsing-Pang; Kung, Hsing-Jien; Wang, Wen-Ching 分享 收藏 分享 收藏 Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimizationLi, Mu-Chun; Lin, Wen-Hsing; Wang, Pei-Chen; Su, Yu-Chieh; Chen, Pei-Yi; Fan, Chu-Min; Chen, Ching-Ping; Huang, Chen-Lung; Chiu, Chun-Hsien; Chang, Ling; Chen, Chiung-Tong; Yeh, Teng-Kuang; Hsieh, Hsing-Pang 分享 收藏 Discovery of BPR1R024, an Orally Active and Selective CSF1R Inhibitor that Exhibits Antitumor and Immunomodulatory Activity in a Murine Colon Tumor ModelLee, Kun-Hung; Yen, Wan-Ching; Lin, Wen-Hsing; Wang, Pei-Chen; Lai, You-Liang; Su, Yu-Chieh; Chang, Chun-Yu; Wu, Cai-Syuan; Huang, Yu-Chen; Yang, Chen-Ming; Chou, Ling-Hui; Yeh, Teng-Kuang; Chen, Chiung-Tong; Shih, Chuan; Hsieh, Hsing-Pang 分享 收藏 分享 收藏 
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