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F

Frank Jühling

INSERM
H指数:25
被引数:9,910

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Claudin-1 targeting suppresses tumor growth, invasion, and metastasis in patient-derived cholangiocarcinoma models

靶向Claudin-1抑制患者来源的胆管癌模型的肿瘤生长、侵袭和转移

Science Translational Medicine
IF14.6
2026-01-010
OA
Zeina Nehme; Marion Müller; Jade Brochon; Émilie Crouchet; Frank Jühling; Mélissa Messé; Laura Heydmann; Julien Moehlin; Romain Désert; Fabio Del Zompo; Christine Thumann; Joachim Lupberger; Natascha Roehlen; Emanuele Felli; Patrick Pessaux; Aïna Venkatasamy; Patrice Marchand; Mihaela Alina Onea; Roberto Iacone; Markus Meyer; Alberto Toso; Nabeel M. Bardeesy; Daniela Sia; Josep Maria Llovet; Yujin Hoshida; Lipika Goyal; Mirian Fernández-Vaquero; Vikas Ranvir; Mathias F Heikenwälder; Tessa Ostyn; Tania Roskams; Patrice Laquerrière; Laurent Mailly; Catherine Schuster; Thomas F. Baumert
Targeting peroxiredoxin 2 prevents hepatocarcinogenesis in metabolic liver disease models
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2025-11-030
OA
Crouchet, Emilie; Schaeffer, Eugenie; Oudot, Marine A.; Moehlin, Julien; Gadenne, Cloe; Juhling, Frank; El Saghire, Hussein; Fujiwara, Naoto; Zhu, Shijia; Rasha, Fahmida Akter; Durand, Sarah C.; Charlot, Anouk; Ponsolles, Clara; Martin, Romain; Brignon, Nicolas; Del Zompo, Fabio; Meiss-Heydmann, Laura; Parnot, Marie; Hamdane, Nourdine; Heide, Danijela; Hetzer, Jenny; Heikenwalder, Mathias; Felli, Emanuele; Pessaux, Patrick; Pochet, Nathalie; Zoll, Joffrey; Cunniff, Brian; Hoshida, Yujin; Mailly, Laurent; Baumert, Thomas F.; Schuster, Catherine
Claudin-1 is a driver and therapeutic target for cholangiocarcinoma
CANCER RESEARCH
IF16.6
2023-04-140
PRE
Muller, Marion; Nehme, Zeina; Crouchet, Emilie; Juhling, Frank; Rohlen, Natascha; Pessaux, Patrick; Felli, Emanuele; Goyal, Lipika; Meyer, Markus; Iacone, Roberto; Toso, Alberto; Manenti, Luigi; Laquerriere, Patrice; Venkatasamy, Aina; Bardeesy, Nabeel; Schuster, Catherine; Mailly, Laurent; Baumert, Thomas F.
Treatment of HCC with claudin-1-specific antibodies suppresses carcinogenic signaling and reprograms the tumor microenvironment
JOURNAL OF HEPATOLOGY
IF33
2023-02-0125
OAAI
Roehlen, Natascha; Muller, Marion; Nehme, Zeina; Crouchet, Emilie; Juhling, Frank; Del Zompo, Fabio; Cherradi, Sara; Duong, Francois H. T.; Almeida, Nuno; Saviano, Antonio; Fernandez-Vaquero, Mirian; Riedl, Tobias; El Saghire, Houssein; Durand, Sarah C.; Ponsolles, Clara; Oudot, Marine A.; Martin, Romain; Brignon, Nicolas; Felli, Emanuele; Pessaux, Patrick; Lallement, Antonin; Davidson, Irwin; Bandiera, Simonetta; Thumann, Christine; Marchand, Patrice; Moll, Solange; Nicolay, Brandon; Bardeesy, Nabeel; Hoshida, Yujin; Heikenwaelder, Mathias; Iacone, Roberto; Toso, Alberto; Meyer, Markus; Elson, Greg; Schweighoffer, Tamas; Teixeira, Geoffrey; Zeisel, Mirjam B.; Laquerriere, Patrice; Lupberger, Joachim; Schuster, Catherine; Mailly, Laurent; Baumert, Thomas F.
A monoclonal antibody targeting nonjunctional claudin-1 inhibits fibrosis in patient-derived models by modulating cell plasticity
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2022-12-2117
OA
Roehlen, Natascha; Saviano, Antonio; El Saghire, Houssein; Crouchet, Emilie; Nehme, Zeina; Del Zompo, Fabio; Juehling, Frank; Oudot, Marine A.; Durand, Sarah C.; Duong, Francois H. T.; Cherradi, Sara; Motos, Victor Gonzalez; Almeida, Nuno; Ponsolles, Clara; Heydmann, Laura; Ostyn, Tessa; Lallement, Antonin; Pessaux, Patrick; Felli, Emanuele; Cavalli, Andrea; Sgrignani, Jacopo; Thumann, Christine; Koutsopoulos, Olga; Fuchs, Bryan C.; Hoshida, Yujin; Hofmann, Maike; Vyberg, Mogens; Viuff, Birgitte Martine; Galsgaard, Elisabeth D.; Elson, Greg; Toso, Alberto; Meyer, Markus; Iacone, Roberto; Schweighoffer, Tamas; Teixeira, Geoffrey; Moll, Solange; De Vito, Claudio; Roskams, Tania; Davidson, Irwin; Heide, Danijela; Heikenwaelder, Mathias; Zeisel, Mirjam B.; Lupberger, Joachim; Mailly, Laurent; Schuster, Catherine; Baumert, Thomas F.
A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery
NATURE COMMUNICATIONS
IF15.7
2021-09-1726
OAAI
Crouchet, Emilie; Bandiera, Simonetta; Fujiwara, Naoto; Li, Shen; El Saghire, Hussein; Fernandez-Vaquero, Mirian; Riedl, Tobias; Sun, Xiaochen; Hirschfield, Hadassa; Juhling, Frank; Zhu, Shijia; Roehlen, Natascha; Ponsolles, Clara; Heydmann, Laura; Saviano, Antonio; Qian, Tongqi; Venkatesh, Anu; Lupberger, Joachim; Verrier, Eloi R.; Sojoodi, Mozhdeh; Oudot, Marine A.; Duong, Francois H. T.; Masia, Ricard; Wei, Lan; Thumann, Christine; Durand, Sarah C.; Gonzalez-Motos, Victor; Heide, Danijela; Hetzer, Jenny; Nakagawa, Shigeki; Ono, Atsushi; Song, Won-Min; Higashi, Takaaki; Sanchez, Roberto; Kim, Rosa S.; Bian, C. Billie; Kiani, Karun; Croonenborghs, Tom; Subramanian, Aravind; Chung, Raymond T.; Straub, Beate K.; Schuppan, Detlef; Ankavay, Maliki; Cocquerel, Laurence; Schaeffer, Evelyne; Goossens, Nicolas; Koh, Anna P.; Mahajan, Milind; Nair, Venugopalan D.; Gunasekaran, Ganesh; Schwartz, Myron E.; Bardeesy, Nabeel; Shalek, Alex K.; Rozenblatt-Rosen, Orit; Regev, Aviv; Felli, Emanuele; Pessaux, Patrick; Tanabe, Kenneth K.; Heikenwaelder, Mathias; Schuster, Catherine; Pochet, Nathalie; Zeisel, Mirjam B.; Fuchs, Bryan C.; Hoshida, Yujin; Baumert, Thomas F.
A genome-wide gain-of-function screen identifies CDKN2C as a HBV host factor
NATURE COMMUNICATIONS
IF15.7
2020-06-0114
OAAI
Eller, Carla; Heydmann, Laura; Colpitts, Che C.; El Saghire, Houssein; Piccioni, Federica; Juhling, Frank; Majzoub, Karim; Pons, Caroline; Bach, Charlotte; Lucifora, Julie; Lupberger, Joachim; Nassal, Michael; Cowley, Glenn S.; Fujiwara, Naoto; Hsieh, Sen-Yung; Hoshida, Yujin; Felli, Emanuele; Pessaux, Patrick; Sureau, Camille; Schuster, Catherine; Root, David E.; Verrier, Eloi R.; Baumert, Thomas F.
Comparison between transcriptomic responses to short-term stress exposures of a common Holarctic and endemic Lake Baikal amphipods
BMC GENOMICS
IF3.7
2019-09-1320
OAAI
Drozdova, Polina; Rivarola-Duarte, Lorena; Bedulina, Daria; Axenov-Gribanov, Denis; Schreiber, Stephan; Gurkov, Anton; Shatilina, Zhanna; Vereshchagina, Kseniya; Lubyaga, Yulia; Madyarova, Ekaterina; Otto, Christian; Juhling, Frank; Busch, Wibke; Jakob, Lena; Lucassen, Magnus; Sartoris, Franz Josef; Hackermueller, Joerg; Hoffmann, Steve; Poertner, Hans-Otto; Luckenbach, Till; Timofeyev, Maxim; Stadler, Peter F.
Combined Analysis of Metabolomes, Proteomes, and Transcriptomes of Hepatitis C Virus-Infected Cells and Liver to Identify Pathways Associated With Disease Development
GASTROENTEROLOGY
IF25.1
2019-08-0184
OAAI
Lupberger, Joachim; Croonenborghs, Tom; Suarez, Armando Andres Roca; Van Renne, Nicolaas; Juhling, Frank; Oudot, Marine A.; Virzi, Alessia; Bandiera, Simonetta; Jamey, Carole; Meszaros, Gergo; Brumaru, Daniel; Mukherji, Atish; Durand, Sarah C.; Heydmann, Laura; Verrier, Eloi R.; El Saghire, Hussein; Hamdane, Nourdine; Bartenschlager, Ralf; Fereshetian, Shaunt; Ramberger, Evelyn; Sinha, Rileen; Nabian, Mohsen; Everaert, Celine; Jovanovic, Marko; Mertins, Philipp; Carr, Steven A.; Chayama, Kazuaki; Dali-Youcef, Nassim; Ricci, Romeo; Bardeesy, Nabeel M.; Fujiwara, Naoto; Gevaert, Olivier; Zeisel, Mirjam B.; Hoshida, Yujin; Pochet, Nathalie; Baumert, Thomas F.
HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response
GASTROENTEROLOGY
IF25.1
2019-06-01195
OAAI
Hamdane, Nourdine; Juhling, Frank; Crouchet, Emilie; El Saghire, Houssein; Thumann, Christine; Oudot, Marine A.; Bandiera, Simonetta; Saviano, Antonio; Ponsolles, Clara; Suarez, Armando Andres Roca; Li, Shen; Fujiwara, Naoto; Ono, Atsushi; Davidson, Irwin; Bardeesy, Nabeel; Schmidl, Christian; Bock, Christoph; Schuster, Catherine; Lupberger, Joachim; Habersetzer, Francois; Doffoel, Michel; Piardi, Tullio; Sommacale, Daniele; Imamura, Michio; Uchida, Takuro; Ohdan, Hideki; Aikata, Hiroshi; Chayama, Kazuaki; Boldanova, Tujana; Pessaux, Patrick; Fuchs, Bryan C.; Hoshida, Yujin; Zeisel, Mirjam B.; Duong, Francois H. T.; Baumert, Thomas F.
Genomic and transcriptomic heterogeneity of colorectal tumours arising in Lynch syndrome
JOURNAL OF PATHOLOGY
IF5.2
2017-09-0546
OAAI
Binder, Hans; Hopp, Lydia; Schweiger, Michal R.; Hoffmann, Steve; Juehling, Frank; Kerick, Martin; Timmermann, Bernd; Siebert, Susann; Grimm, Christina; Nersisyan, Lilit; Arakelyan, Arsen; Herberg, Maria; Buske, Peter; Loeffler-Wirth, Henry; Rosolowski, Maciej; Engel, Christoph; Przybilla, Jens; Peifer, Martin; Friedrichs, Nicolaus; Moeslein, Gabriela; Odenthal, Margarete; Hussong, Michelle; Peters, Sophia; Holzapfel, Stefanie; Nattermann, Jacob; Hueneburg, Robert; Schmiegel, Wolff; Royer-Pokora, Brigitte; Aretz, Stefan; Kloth, Michael; Kloor, Matthias; Buettner, Reinhard; Galle, Joerg; Loeffler, Markus

研究方向

暂未获取到该数据
T
Thomas F. Baumert
H 指数:79论文数:530被引数:2.1万
P
Peter F. Stadler
H 指数:119论文数:1,324被引数:8.7万
Y
Yujin Hoshida
H 指数:82论文数:481被引数:3.1万
C
Catherine Schuster
H 指数:39论文数:163被引数:4,402
P
Patrick Pessaux
H 指数:62论文数:537被引数:1.5万
J
Joachim Lupberger
H 指数:28论文数:92被引数:3,559
E
Emanuele Felli
H 指数:28论文数:169被引数:2,698
L
Laura Heydmann
H 指数:20论文数:57被引数:1,405
É
Émilie Crouchet
H 指数:18论文数:99被引数:2,337
C
Clara Ponsolles
H 指数:11论文数:26被引数:710