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收藏分享 收藏 分享 收藏 The development of pyridazinone-based andrographolide derivatives as anti-cancer agents with the ability of inhibiting the TFAP4/Wnt/(3-catenin signaling pathway以吡啶azinone为基团的穿心莲内酯衍生物的开发，作为能够抑制TFAP4/Wnt/β-catenin信号通路的抗癌剂
Zhang, Hang; Xu, Zhihao; Xu, Zhengyu; Bian, Shaopan; Qiao, Ning; Wang, Xiaodi; Zhang, Mingwei; Guo, Fan; Cui, You; Zheng, Fanyu; Liu, Jia; Wu, Di; Xu, Haiwei 分享 收藏 分享 收藏 Nicotinamide mononucleotide protects septic hearts in mice via preventing cyclophilin F modification and lysosomal dysfunction烟酰胺单核苷酸通过预防亲环素F修饰和溶酶体功能障碍保护小鼠脓毒症心脏Ni, Rui; Ji, Xiao-yun; Cao, Ting; Liu, Xiu-wen; Wang, Chao; Lu, Chao; Peng, Angel; Zhang, Zhu-xu; Fan, Guo-Chang; Zhang, Jin; Su, Zhao-liang; Peng, Tian-qing 分享 收藏 分享 收藏 Probiotic bacteria-released extracellular vesicles enhance macrophage phagocytosis in polymicrobial sepsis by activating the FPR1/2 pathwayZhu, Ruiyao; Zhang, Yu; Wang, Xiaohong; Liu, Benjamin D.; Chowdhury, Debabrata; Li, Zhixin; Pan, Mingliang; Peng, Tianqing; Chen, Jing; Huang, Wei; Zhan, Liying; Fan, Guo-Chang 分享 收藏 Lipocalin10 is Critical for Macrophage Efferocytosis to Repair Myocardial Ischemia/Reperfusion InjuryLipocalin10对于巨噬细胞清除凋亡细胞以修复心肌缺血/再灌注损伤至关重要。Zhang, Yu; Wang, Xiaohong; Zhu, Ruiyao; Sakabe, Masahide; Chowdhury, Debab Rata; Li, Zhixin; Chen, Jing; Huang, Wei; Xin, Mei; Fan, Guo-Chang 分享 收藏 DNA damage-inducible transcript 3 positively regulates RIPK1-mediated necroptosisNi, Rui; Cao, Ting; Ji, Xiaoyun; Peng, Angel; Zhang, Zhuxu; Fan, Guo-Chang; Stathopulos, Peter; Chakrabarti, Subrata; Su, Zhaoliang; Peng, Tianqing 分享 收藏 A MYC-STAMBPL1-TOE1 positive feedback loop mediates EGFR stability in hepatocellular carcinomaZhang, Hongli; Wang, Zixuan; Zhang, Jian; Li, Zhengtai; Liu, Jiaxuan; Yu, Jingwen; Zhao, Yiqi; Guo, Fan; Chen, Wei-Dong; Wang, Yan-Dong 分享 收藏 Macrophage-enriched Sectm1a promotes efficient efferocytosis to attenuate ischemia/reperfusion-induced cardiac injuryWang, Xiaohong; Du, Wa; Li, Yutian; Yang, Hui -Hui; Zhang, Yu; Akbar, Rubab; Morgan, Hannah; Peng, Tianqing; Chen, Jing; Sadayappan, Sakthivel; Hu, Yueh-Chiang; Fan, Yanbo; Huang, Wei; Fan, Guo-Chang 分享 收藏 BRD9-SMAD2/3 Orchestrates Stemness and Tumorigenesis in Pancreatic Ductal AdenocarcinomaBRD9-SMAD2/3在胰腺导管腺癌中协调了Stemness和肿瘤发生Feng, Yuliang; Cai, Liuyang; Pook, Martin; Liu, Feng; Chang, Chao-Hui; Mouti, Mai Abdel; Nibhani, Reshma; Militi, Stefania; Dunford, James; Philpott, Martin; Fan, Yanbo; Fan, Guo-Chang; Liu, Qi; Qi, Jun; Wang, Cheng; Hong, Wanzi; Morgan, Hannah; Wang, Mingyang; Sadayappan, Sakthivel; Jegga, Anil G.; Oppermann, Udo; Wang, Yigang; Huang, Wei; Jiang, Lei; Pauklin, Siim 分享 收藏 分享 收藏 Junctophilin-2 Promotes Cardiomyocyte Survival By Blocking Murf1-mediated Junctin Ubiquitination And Proteasome-dependent DegradationJunctophilin-2通过阻断Murf1-mediated连接蛋白泛素化和蛋白酶体依赖性降解促进心肌细胞存活Ji, Xiaoyun; Huang, Yifan; Ni, Rui; Fan, Guo-Chang; Zheng, Dong; Jones, Douglas L.; Song, Long-Sheng; Chakrabarti, Subrata; Su, Zhaoliang; Peng, Tianqing 分享 收藏 分享 收藏 分享 收藏 分享 收藏 MLKL-mediated necroptosis is a target for cardiac protection in mouse models of type-1 diabetesCao, Ting; Ni, Rui; Ding, Weimin; Ji, Xiaoyun; Li, Lan; Liao, Guangneng; Lu, Yanrong; Fan, Guo-Chang; Zhang, Zhuxu; Peng, Tianqing 分享 收藏 Sustained over-expression of calpain-2 induces age-dependent dilated cardiomyopathy in mice through aberrant autophagyJi, Xiao-yun; Zheng, Dong; Ni, Rui; Wang, Jin-xi; Shao, Jian-qiang; Vue, Zer; Hinton, Antentor, Jr.; Song, Long-Sheng; Fan, Guo-Chang; Chakrabarti, Subrata; Su, Zhao-liang; Peng, Tian-qing 分享 收藏 
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