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J

J.J.G. Tesmer

biological sciences

55H指数
329论文数
1.1W被引数
收录论文 120
发表时间
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Expressions of Concern, Corrigenda, and a Retraction《关注声明》《勘误表》及《撤稿声明》
errMolecular Pharmacology
IF3
err2026-04-03
err0
PREAI
errBeverley Greenwood-Van Meerveld; John Tesmer; Michael Jarvis
err分享
err收藏
Understanding how a highly prevalent GRK5 polymorphism affects platelets and enhances thrombotic risk
errBlood
IF23.1
err2026-01-22
err0
PREAI
errYanki Yarman; Xuefei Zhao; Hyunsook Ahn; Hannah Thomson; Amrita Sarkar; Tian Yuan; Meghan Roberts; Jeremy G.T Wurtzel; Scott L. Diamond; John J. G. Tesmer; Deborah L. French; Maurizio Tomaiuolo; Ernest Turro; William J. Astle; Lawrence E. Goldfinger; Steven E. McKenzie; Jeffrey L. Benovic; Timothy J. Stalker; Mortimer Poncz; Peisong Ma
err分享
err收藏
Oligomerization of Transmembrane Adenylyl Cyclase Isoforms
errMolecular Pharmacology
IF3
err2026-01-08
err0
PREAI
errSadikshya Aryal; John J.G. Tesmer; Carmen W. Dessauer; Val J. Watts
err分享
err收藏
High-Throughput Cardiac Hypertrophy Phenotyping Supports Lead Optimization of GRK5 Inhibitors高通量心脏肥厚表型分析支持GRK5抑制剂的先导化合物优化
errACS Medicinal Chemistry Letters
IF4
err2025-12-15
err0
errOAAI
errPia Steinkuhl; Anca Kliesow Remes; Carmen Carrillo García; Amol Sonawane; Ranjith Kumar Gadi; Arun K. Ghosh; John J. G. Tesmer; Oliver J. Müller; Dennis Schade
err分享
err收藏
Potent and Selective G Protein-coupled Receptor Kinase 5 Inhibitors: Design, Synthesis, Evaluation, and X-ray Structural Studies强效且选择性的G蛋白偶联受体激酶5抑制剂：设计、合成、评价和X射线结构研究
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-11-26
err0
PREAI
errArun K. Ghosh; Rajesh Manda; Ranjith Kumar Gadi; Yueyi Chen; Natalie M. Galvan; John J.G. Tesmer
err分享
err收藏
Structural insights into the catalytic cycle of G protein–coupled receptor kinase 5 and a possible regulatory site for potassium ionG蛋白偶联受体激酶5催化循环的结构见解以及一个可能的钾离子调节位点
errJournal of Biological Chemistry
IF3.9
err2025-07-01
err0
errOAAI
errYueyi Chen; John J.G. Tesmer
err分享
err收藏
Potent, Selective, and Drug-like G Protein-coupled Receptor Kinase 5 and 6 Inhibitors: Design, Synthesis, and X-ray Structural Studies强效、选择性且具有药物样特性的G蛋白偶联受体激酶5和6抑制剂：设计、合成与X射线结构研究
errChemMedChem
IF3.4
err2025-05-19
err0
PREAI
errArun K Ghosh; Ranjith Kumar Gadi; Yueyi Chen; Sandali Piladuwa Gamage; Kathryn McCauley; John J. G. Tesmer
err分享
err收藏
Structural Insights into G Protein-Coupled Receptor Kinase 5 Phosphorylation of Neurotensin Receptor 1G蛋白偶联受体激酶5对神经紧张素受体1磷酸化的结构洞察
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-03-01
err0
PREAI
errXiao, Jiaqi; Tesmer, John
err分享
err收藏
G Protein-Coupled Receptor Kinase Isoforms Differentially Regulate Dopamine Receptor SubtypesG蛋白偶联受体激酶异构体差异调控多巴胺受体亚型
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-03-01
err0
PREAI
errMoritz, Amy; Madaras, Nora s.; Snyder, Kirsten k.; Boldizsar, Noelia m.; Haider, Raphael; Drube, Julia; Ghosh, Arun k.; Tesmer, John; Hoffmann, Carsten; Sibley, David r.
err分享
err收藏
Therapeutic Efficacy of a Novel Pharmacologic GRK2 Inhibitor in Multiple Animal Models of Heart Failure新型GRK2抑制剂在多种心力衰竭动物模型中的治疗效果
errJACC-BASIC TO TRANSLATIONAL SCIENCE
IF7.2
err2025-02-01
err1
errOAAI
errRoy, Rajika; Schumacher, Sarah M.; Murphy, Haley Christine; Grondolsky, Jessica; Rosales, Thiele Osvaldt; Chuprun, J. Kurt; Gao, Erhe; Zhao, Huaqing; Berretta, Remus M.; Hobby, Alexander R. H.; Houser, Steven R.; V. Avramova, Larisa; Tesmer, John J. G.; Koch, Walter J.
err分享
err收藏
Design, synthesis, and X-ray structural studies of a series of highly potent selective, and drug-like G protein-coupled receptor kinase 5 inhibitors
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-01-01
err0
PREAI
errGhosh, Arun K.; Chen, Yueyi; Gadi, Ranjith Kumar; Sonawane, Amol; Gamage, Sandali Piladuwa; Tesmer, John J. G.
err分享
err收藏
Rescue of Familial Lecithin:Cholesterol Acyltranferase Deficiency Mutations with an Allosteric Activator
errMOLECULAR PHARMACOLOGY
IF3
err2024-10-01
err1
errOAAI
errManthei, Kelly A.; Tremonti, Grace E.; Chang, Louise; Niemela, Akseli; Giorgi, Laura; Koivuniemi, Artturi; Tesmer, John Joseph Grubb
err分享
err收藏
New Mechanisms Underlying Oncogenesis in Dbl Family Rho Guanine Nucleotide Exchange Factors
errMOLECULAR PHARMACOLOGY
IF3
err2024-09-01
err1
errOAAI
errRavala, Sandeep K.; Tesmer, John J. G.
err分享
err收藏
Structural Basis Of Apolipoprotein A1 Activation Of Lecithin:Cholesterol Acyl Transferase In High Density Lipoproteins
errARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
IF7.4
err2024-05-01
err0
PREAI
errColeman, Bethany; Bedi, Shimpi; Morris, Jamie C.; Hart, Rachel; Jerome, W. Gray; Manthei, Kelly A.; Vaisar, Tomas; Tesmer, John; Aller, Stephen; Davidson, William
err分享
err收藏
Structure of adenylyl cyclase 5 in complex with Gβγ offers insights into ADCY5-related dyskinesia
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2024-04-08
err1
PREAI
errYen, Yu-Chen; Li, Yong; Chen, Chun-Liang; Klose, Thomas; Watts, Val J.; Dessauer, Carmen W.; Tesmer, John J. G.
err分享
err收藏
Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2024-04-02
err0
errOAAI
errChen, Chun-Liang; Syahirah, Ramizah; Ravala, Sandeep K.; Yen, Yu-Chen; Klose, Thomas; Deng, Qing; Tesmer, John J. G.
err分享
err收藏
Structural insights and rational design, optimization of highly potent and selective novel GRK5/6 inhibitors for cancer therapy
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errChen, Yueyi; Sonawane, Amol D.; Manda, Rajesh; Gadi, Ranjith K.; Ghosh, Arun K.; Tesmer, John J.
err分享
err收藏
Development of a new class of potent and highly selective G protein-coupled receptor kinase 5 inhibitors and structural insight from crystal structures of inhibitor complexes
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-01-01
err3
PREAI
errChen, Yueyi; Sonawane, Amol; Manda, Rajesh; Gadi, Ranjith Kumar; Tesmer, John J. G.; Ghosh, Arun K.
err分享
err收藏
Structural and Mechanistic Basis for Gbetagamma-mediated Activation of Phosphoinositide 3-kinase-gamma
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2023-06-01
err0
errOAAI
errChen, Chun-Liang; Ravala, Sandeep; Yen, Yu-Chen; Klose, Thomas; Syahirah, Ramizah; Tesmer, John J. G.; Deng, Qing
err分享
err收藏
Therapeutic Efficacy of a Novel Pharmacologic GRK2 Inhibitor in Mice Models of Heart Failure
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2023-06-01
err0
errOAAI
errRoy, Rajika; Schumacher, Sarah; Murphy, Haley C.; Grondolsky, Jessica; Chuprun, Kurt; Waldschmidt, Helen V.; Gao, Erhe; Zhao, Huaqing; Avramova, Larisa; Tesmer, John J. G.; Koch, Walter
err分享
err收藏

研究方向

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合作学者
合作期刊
R
Robert J. Lefkowitz
H 指数: 213 · 论文数: 858
A
Arul M. Chinnaiyan
H 指数: 144 · 论文数: 1.7K
G
GutkindJ.Silvio (J. Silvio Gutkind)
H 指数: 140 · 论文数: 1.3K
A
Alfred G. Gilman
H 指数: 133 · 论文数: 382
K
Krzysztof Palczewski
H 指数: 115 · 论文数: 737
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