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Novel Syngeneic Cell Lines for Studying High-Risk BRAFV600E-Driven Colorectal Cancer In Vivo Traichel, J.; Metzger, A.; Walz, M.; Feuerstein, R.; Wohlfeil, N.; Metzger, P.; Marx, L.; Asdih, C.; Lindenthal, A.; Seger, A.; et al. 新型同种细胞系用于研究高危BRAFv600E驱动的结直肠癌在体模型。Cancer Res. Commun. 2026, 6, 320–339. [Google Scholar] [CrossRef] Traichel, Jasmin; Metzger, Ariane; Walz, Maria; Feuerstein, Reinhild; Wohlfeil, Nadine; Metzger, Patrick; Marx, Lisa; Asdih, Celia; Lindenthal, Agnes; Seger, Alina; Schrimpf, Jule; Nardella, Luigi L.; Kowar, Silke; Frew, Ian J.; Halbach, Sebastian; Kesselring, Rebecca; Boerries, Melanie; Griffin, Ricarda; Brummer, Tilman 分享 收藏
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FLT3-ITD Driven CMTM6 Expression Contributes to Immune Escape of Acute Myeloid Leukemia FLT3-ITD 驱动的 CMTM6 表达促进了急性髓系白血病的免疫逃逸。 Zwick, Melissa; Zinkel, Bastian; Spohr, Corinna; Rueckert, Tamina; Halbach, Sebastian; Shoumariyeh, Khalid; Braun, Lukas M.; Nelde, Annika; Maerklin, Melanie; Holzmayer, Samuel J.; Duquesne, Sandra; Schlaak, Alexandra Emilia; Otto-Mora, Patricia; Bengsch, Bertram; Schiff, Marcel; Kissel, Sandra; Follo, Marie; Altmann, Heidi; Kunadt, Desiree; Illert, Anna Lena; Walz, Juliane S.; Walz, Gerd; Duyster, Justus; Schetelig, Johannes; Brummer, Tilman; Zeiser, Robert; Koehler, Natalie 分享 收藏
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Comprehensive genetic profiling and molecularly guided treatment for patients with primary CNS tumors Kuehn, Julia C.; Metzger, Patrick; Neidert, Nicolas; Matysiak, Uta; Graessel, Linda; Philipp, Ulrike; Bleul, Sabine; Pauli, Thomas; Falkenstein, Julia; Bertemes, Henriette; Cysar, Stepan; Hess, Maria Elena; Frey, Anna Verena; Duque-Afonso, Jesus; Schorb, Elisabeth; Machein, Marcia; Beck, Juergen; Schnell, Oliver; von Bubnoff, Nikolas; Illert, Anna L.; Peters, Christoph; Brummer, Tilman; Prinz, Marco; Miething, Cornelius; Becker, Heiko; Lassmann, Silke; Werner, Martin; Boerries, Melanie; Duyster, Justus; Heiland, Dieter H.; Sankowski, Roman; Scherer, Florian 分享 收藏
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Oncogene-induced TIM-3 ligand expression dictates susceptibility to anti-TIM-3 therapy in mice 癌基因诱导的TIM-3配体表达决定了小鼠对anti-TIM-3治疗的敏感性 Talvard-Balland, Nana; Braun, Lukas M.; Dixon, Karen O.; Zwick, Melissa; Engel, Helena; Hartmann, Alina; Duquesne, Sandra; Penter, Livius; Andrieux, Geoffroy; Rindlisbacher, Lukas; Acerbis, Andrea; Ehmann, Jule; Koellerer, Christoph; Ansuinelli, Michela; Rettig, Andres; Moschallski, Kevin; Apostolova, Petya; Brummer, Tilman; Illert, Anna L.; Schramm, Markus A.; Cheng, Yurong; Koettgen, Anna; Duyster, Justus; Menssen, Hans D.; Ritz, Jerome; Blazar, Bruce R.; Boerries, Melanie; Schmitt-Graeff, Annette; Sariipek, Nurefsan; Van Galen, Peter; Buescher, Joerg M.; Cabezas-Wallscheid, Nina; Pahl, Heike L.; Pearce, Erika L.; Soiffer, Robert J.; Wu, Catherine J.; Vago, Luca; Becher, Burkhard; Koehler, Natalie; Wertheimer, Tobias; Kuchroo, Vijay K.; Zeiser, Robert 分享 收藏
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REBOUND GROWTH AFTER MAPKI WITHDRAWAL INVOLVES RAPID MAPK REACTIVATION AND CYTOKINE-MEDIATED MICROGLIA RECRUITMENT IN PEDIATRIC LOW-GRADE GLIOMA MODEL Kocher, Daniela; Cao, Lei; Guiho, Romain; Langhammer, Melanie; Lai, Yun-Lu; Becker, Pauline; Friedel, Dennis; Selt, Florian; Vonhoeren, David; Zaman, Julia; Valinciute, Gintvile; Herter, Sonja; Rettenmeier, Johanna; Maass, Kendra K.; Pajtler, Kristian W.; von Deimling, Andreas; Pusch, Stefan; Pfister, Stefan M.; Oehme, Ina; Jones, David T. W.; Halbach, Sebastian; Brummer, Tilman; Martinez-Barbera, Juan Pedro; Witt, Olaf; Milde, Till; Sigaud, Romain 分享 收藏
INTEGRATED MULTI-OMICS EXPLORATION OF MAPK PATHWAY INHIBITION IN PEDIATRIC PILOCYTIC ASTROCYTOMA Sigaud, Romain; Stefanski, Anja; Selt, Florian; Usta, Diren; Kocher, Daniela; Picard, Daniel; Buedenbender, Isabel; Remke, Marc; Pfister, Stefan M.; Jones, David T. W.; Brummer, Tilman; Witt, Olaf; Milde, Till 分享 收藏
Oncogenic Calreticulin Induces Immune Escape by Stimulating TGFβ Expression and Regulatory T-cell Expansion in the Bone Marrow Microenvironment 致癌钙网蛋白通过刺激骨髓微环境中tgf β 表达和调节性T细胞扩增诱导免疫逃逸 Schmidt, Dominik; Endres, Cornelia; Hoefflin, Rouven; Andrieux, Geoffroy; Zwick, Melissa; Karantzelis, Nikolaos; Staehle, Hans F.; Vinnakota, Janaki Manoja; Duquesne, Sandra; Mozaffari Jovein, Miriam; Pfeifer, Dietmar; Becker, Heiko; Blazar, Bruce R.; Zaehringer, Alexander; Duyster, Justus; Brummer, Tilman; Boerries, Melanie; Baumeister, Julian; Shoumariyeh, Khalid; Li, Juan; Green, Anthony R.; Heidel, Florian H.; Tirosh, Itay; Pahl, Heike L.; Leimkuehler, Nils; Koehler, Natalie; de Toledo, Marcelo A. S.; Koschmieder, Steffen; Zeiser, Robert 分享 收藏
Rebound growth of BRAF mutant pediatric glioma cells after MAPKi withdrawal is associated with MAPK reactivation and secretion of microglia-recruiting cytokines Kocher, Daniela; Cao, Lei; Guiho, Romain; Langhammer, Melanie; Lai, Yun-Lu; Becker, Pauline; Hamdi, Hiba; Friedel, Dennis; Selt, Florian; Vonhoeren, David; Zaman, Julia; Valinciute, Gintvile; Herter, Sonja; Picard, Daniel; Rettenmeier, Johanna; Maass, Kendra K.; Pajtler, Kristian W.; Remke, Marc; von Deimling, Andreas; Pusch, Stefan; Pfister, Stefan M.; Oehme, Ina; Jones, David T. W.; Halbach, Sebastian; Brummer, Tilman; Martinez-Barbera, Juan Pedro; Witt, Olaf; Milde, Till; Sigaud, Romain 分享 收藏
Inflammation plays an important role in the progression of chronic myeloid leukemia Langhammer, Melanie; Schopf, Julia; Jaquet, Timo; Horn, Katharina; Angel, Moritz; Mohl, Daniel; Lagies, Simon; Spohr, Corinna; Christen, Daniel; Uhl, Franziska Maria; Maie, Tiago; Jacobi, Henrike; Feyerabend, Thorsten B.; Huber, Julia; Panning, Marcus; Sitaru, Cassian; Costa, Ivan; Zeiser, Robert; Aumann, Konrad; Becker, Heiko; Braunschweig, Till; Koschmieder, Steffen; Kammerer, Bernd; Shoumariyeh, Khalid; Huber, Michael; Schemionek-Reinders, Mirle; Brummer, Tilman; Halbach, Sebastian 分享 收藏
Novel mouse models to study the role of the docking protein GAB2 in general and in cancer Angel, Moritz; Klappstein, Vanessa; Schrimpf, Jule; Langhammer, Melanie; Shoumariyeh, Khalid; Miething, Cornelius; Kloz, Ulrich; Armstrong, Brittney; van der Hoeven, Franciscus; Brummer, Tilman; Halbach, Sebastian 分享 收藏
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease Maas-Bauer, Kristina; Stell, Anna-Verena; Yan, Kai-Li; de Vega, Enrique; Vinnakota, Janaki Manoja; Unger, Susanne; Nunez, Nicolas; Norona, Johana; Talvard-Balland, Nana; Kossmann, Stefanie; Schwan, Carsten; Miething, Cornelius; Martens, Uta S.; Shoumariyeh, Khalid; Nestor, Rosa P.; Duquesne, Sandra; Hanke, Kathrin; Rackiewicz, Michal; Hu, Zehan; El Khawanky, Nadia; Taromi, Sanaz; Andrlova, Hana; Faraidun, Hemin; Walter, Stefanie; Pfeifer, Dietmar; Follo, Marie; Waldschmidt, Johannes; Melchinger, Wolfgang; Rassner, Michael; Wehr, Claudia; Schmitt-Graeff, Annette; Halbach, Sebastian; Liao, James; Haecker, Georg; Brummer, Tilman; Dengjel, Joern; Andrieux, Geoffroy; Grosse, Robert; Tugues, Sonia; Blazar, Bruce R.; Becher, Burkhard; Boerries, Melanie; Zeiser, Robert 分享 收藏
The nNGM Preclinical Platform: Preclinical research to generate evidence for patients with non-small cell lung cancer harboring variants of unknown significance Ziegler, M.; Albers-Leischner, C.; Salgueiro, L.; Khoury, N.; Sharapova, Y.; Saalfeld, F. C.; Wenzel, C.; Scharpenseel, H.; Schmidt, C.; Naveja-Romero, J.; Meemboor, S.; Hillmer, A.; Nogova, L.; Wermke, M.; Wolf, J.; Diederichs, S.; Brummer, T.; Buettner, R.; Janning, M.; Loges, S. 分享 收藏
BRAFΔß3-αC in-frame deletion mutants differ in their dimerization propensity, HSP90 dependence, and druggability Lauinger, Manuel; Christen, Daniel; Klar, Rhena F. U.; Roubaty, Carole; Heilig, Christoph E.; Stumpe, Michael; Knox, Jennifer J.; Radulovich, Nikolina; Tamblyn, Laura; Xie, Irene Y.; Horak, Peter; Forschner, Andrea; Bitzer, Michael; Wittel, Uwe A.; Boerries, Melanie; Ball, Claudia R.; Heining, Christoph; Glimm, Hanno; Froehlich, Martina; Huebschmann, Daniel; Gallinger, Steven; Fritsch, Ralph; Froehling, Stefan; O'Kane, Grainne M.; Dengjel, Joern; Brummer, Tilman 分享 收藏
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