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Effective therapeutic targeting of CTNNB1-mutant hepatoblastoma with WNTinib CTNNB1突变型肝母细胞瘤的有效治疗性靶向WNTinib Balaseviciute, Ugne; Huguet-Pradell, Julia; Abril-Fornaguera, Jordi; Gris-Oliver, Albert; Rialdi, Alex; Fernandez-Martinez, Elisa; Montironi, Carla; Del Pozo, Vanessa; Houghton, Peter; Zanatto, Laura; Mesropian, Agavni; Keraite, Ieva; Thung, Swan; Armengol, Carolina; Sancho-Bru, Pau; Guccione, Ernesto; Pinyol, Roser; Llovet, Josep M. 分享 收藏
NEDD8-specific protease 1 deficiency as a novel driver of hepatoblastoma development through dysregulation of the CAND1-NEDD8 pathway NEDD8特异性蛋白酶1缺乏通过CAND1-NEDD8通路失调作为肝母细胞瘤发展的新型驱动因素 Zapata-Pavas, L. Estefania; Serrano-Macia, Marina; Merlos Rodrigo, Miguel Angel; Barrenechea-Barrenechea, Jon Ander; Pena-Sanfelix, Patricia; Del Rio-Alvarez, Alvaro; Gil-Pitarch, Claudia; Rejano-Gordillo, Claudia M.; Goikoetxea-Usandizaga, Naroa; Gonzalez-Recio, Irene; Michalkova, Hana; Mercado-Gomez, Maria; Lachiondo-Ortega, Sofia; Castaneda, Andrea; Asensio, Maitane; Murti, Abhishek; Lelou, Elise; Nogueiras, Ruben; Mayor, Ugo; Heger, Zbynek; Sancho-Bru, Pau; Delgado, Teresa C.; Calvisi, Diego F.; Xirodimas, Dimitris P.; Wang, Bruce; Marin, Jose J. G.; Fernandez-Barrena, Maite G.; Armengol, Carolina; Avila, Matias; Martinez-Chantar, Maria Luz 分享 收藏
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Cathepsin D is essential for the degradomic shift of macrophages required to resolve liver fibrosis Ruiz-Blazquez, Paloma; Fernandez-Fernandez, Maria; Pistorio, Valeria; Martinez-Sanchez, Celia; Costanzo, Michele; Iruzubieta, Paula; Zhuravleva, Ekaterina; Cacho-Pujol, Julia; Arino, Silvia; Del Castillo-Cruz, Alejandro; Nunez, Susana; Andersen, Jesper B.; Ruoppolo, Margherita; Crespo, Javier; Garcia-Ruiz, Carmen; Pavone, Luigi Michele; Reinheckel, Thomas; Sancho-Bru, Pau; Coll, Mar; Fernandez-Checa, Jose C.; Moles, Anna 分享 收藏
Alcoholic Foamy Degeneration, an Entity Resembling Alcohol-Associated Hepatitis: Diagnosis, Prognosis, and Molecular Profiling Gratacos-Gines, Jordi; Avitabile, Emma; Montironi, Carla; Guillamon-Thiery, Alex; Hernandez-Evole, Helena; Moreta, Maria Jose; Blaya, Delia; Arino, Silvia; Rubio, Ana Belen; Perez-Guasch, Martina; Cervera, Marta; Carol, Marta; Fabrellas, Nuria; Soria, Anna; Juanola, Adria; Graupera, Isabel; Sancho-Bru, Pau; Diaz, Alba; Coll, Mar; Bataller, Ramon; Gines, Pere; Pose, Elisa 分享 收藏
Recurrent alcohol-associated hepatitis is common and is associated with increased mortality Gratacos-Gines, Jordi; Ruz-Zafra, Pilar; Celada-Sendino, Miriam; Marti-Carretero, Aina; Pujol, Claudia; Martin-Mateos, Rosa; Echavarria, Victor; Frisancho, Luis E.; Garcia, Sonia; Barreales, Monica; Tejedor-Tejada, Javier; Vazquez-Rodriguez, Sergio; Canete, Nuria; Fernandez-Carrillo, Carlos; Valenzuela, Maria; Marti-Aguado, David; Horta, Diana; Quinones, Marta; Bernal-Monterde, Vanesa; Acosta, Silvia; Artaza, Tomas; Pinazo, Jose; Villar-Lucas, Carmen; Clemente-Sanchez, Ana; Badia-Aranda, Ester; Giraldez-Gallego, Alvaro; Rodriguez, Manuel; Sancho-Bru, Pau; Cabezas, Joaquin; Ventura-Cots, Meritxell; Fernandez-Rodriguez, Conrado; Aguilera, Victoria; Tome, Santiago; Bataller, Ramon; Caballeria, Juan; Pose, Elisa 分享 收藏
Roadmap to DILI research in Europe. A proposal from COST action ProEuroDILINet Lucena, M. I.; Villanueva-Paz, M.; Alvarez-Alvarez, I.; Aithal, G. P.; Bjornsson, E. S.; Cakan-Akdogan, G.; Cubero, F. J.; Esteves, F.; Falcon-Perez, J. M.; Fromenty, B.; Garcia-Ruiz, C.; Grove, J. I.; Konu, O.; Kranendonk, M.; Kullak-Ublick, G. A.; Miranda, J. P.; Remesal-Doblado, A.; Sancho-Bru, P.; Nelsons, L.; Andrade, R. J.; Daly, A. K.; Fernandez-Checa, J. C. 分享 收藏
Anti-miR-873-5p improves alcohol-related liver disease by enhancing hepatic deacetylation via SIRT1 Anti-miR-873-5p通过SIRT1增强肝脏去乙酰化改善酒精相关性肝病 Rodriguez-Agudo, Ruben; Gonzalez-Recio, Irene; Serrano-Macia, Marina; Bravo, Miren; Petrov, Petar; Blaya, Delia; Herranz, Jose Maria; Mercado-Gomez, Maria; Rejano-Gordillo, Claudia Maria; Lachiondo-Ortega, Sofia; Gil-Pitarch, Claudia; Azkargorta, Mikel; Van Liempd, Sebastiaan Martijn; Martinez-Cruz, Luis Alfonso; Simao, A. L.; Elortza, Felix; Martin, Cesar; Nevzorova, Yulia A.; Cubero, Francisco Javier; Delgado, Teresa C.; Argemi, Josepmaria; Bataller, Ramon; Schoonjans, Kristina; Banales, Jesus M.; Castro, Rui E.; Sancho-Bru, Pau; Avila, Matias A.; Julve, Josep; Jover, Ramiro; Mabe, Jon; Simon, Jorge; Goikoetxea-Usandizaga, Naroa; Martinez-Chantar, Maria L. 分享 收藏
Ductular reaction-associated neutrophils promote biliary epithelium proliferation in chronic liver disease 慢性肝病中与导管反应相关的中性粒细胞促进胆管上皮增殖 Arino, Silvia; Aguilar-Bravo, Beatriz; Coll, Mar; Lee, Woo -Yong; Peiseler, Moritz; Cantallops-Vila, Paula; Sererols-Vinas, Laura; de la Torre, Raquel A. Martinez-Garcia; Martinez-Sanchez, Celia; Pedragosa, Jordi; Zanatto, Laura; Gratacos-Gines, Jordi; Pose, Elisa; Blaya, Delia; Almodovar, Xenia; Fernandez-Fernandez, Maria; Ruiz-Blazquez, Paloma; Lozano, Juan Jose; Affo, Silvia; Planas, Anna M.; Gines, Pere; Moles, Anna; Kubes, Paul; Sancho-Bru, Pau 分享 收藏
Identification and experimental validation of druggable epigenetic targets in hepatoblastoma Claveria-Cabello, Alex; Herranz, Jose Maria; Latasa, Maria Ujue; Arechederra, Maria; Uriarte, Iker; Pineda-Lucena, Antonio; Prosper, Felipe; Berraondo, Pedro; Alonso, Cristina; Sangro, Bruno; Marin, Jose Juan Garcia; Martinez-Chantar, Maria Luz; Ciordia, Sergio; Corrales, Fernando Jose; Francalanci, Paola; Alaggio, Rita; Zucman-Rossi, Jessica; Indersie, Emilie; Cairo, Stefano; Domingo-Sabat, Montserrat; Zanatto, Laura; Sancho-Bru, Pau; Armengol, Carolina; Berasain, Carmen; Fernandez-Barrena, Maite Garcia; Avila, Matias Antonio 分享 收藏
Therapeutic targeting of adipose tissue macrophages ameliorates liver fibrosis in non-alcoholic fatty liver disease Martinez-Sanchez, Celia; Bassegoda, Octavi; Deng, Hongping; Almodovar, Xenia; Ibarzabal, Ainitze; de Hollanda, Ana; de la Torre, Raquel-Adela Martinez Garcia; Blaya, Delia; Arino, Silvia; Jimenez-Esquivel, Natalia; Aguilar-Bravo, Beatriz; Vallverdu, Julia; Montironi, Carla; Osorio-Conles, Oscar; Fundora, Yiliam; Moreno, Francisco Javier Sanchez; Gomez-Valades, Alicia G.; Aguilar-Corominas, Laia; Soria, Anna; Pose, Elisa; Juanola, Adria; Cervera, Marta; Perez, Martina; Hernandez-Gea, Virginia; Affo, Silvia; Swanson, Kelly S.; Ferrer-Fabrega, Joana; Balibrea, Jose Maria; Sancho-Bru, Pau; Vidal, Josep; Gines, Pere; Smith, Andrew M.; Graupera, Isabel; Coll, Mar 分享 收藏
Hepatocyte dedifferentiation profiling in alcohol-related liver disease identifies CXCR4 as a driver of cell reprogramming 酒精相关性肝病中的肝细胞去分化分析将CXCR4鉴定为细胞重编程的驱动因素 Aguilar-Bravo, Beatriz; Arino, Silvia; Blaya, Delia; Pose, Elisa; de la Torre, Raquel A. Martinez Garcia; Latasa, Maria U.; Martinez-Sanchez, Celia; Zanatto, Laura; Sererols-Vinas, Laura; Cantallops-Vila, Paula; Affo, Silvia; Coll, Mar; Thillen, Xavier; Dubuquoy, Laurent; Avila, Matias A.; Argemi, Josepmaria; Paz, Arantza Lamas; Nevzorova, Yulia A.; Cubero, Francisco Javier; Bataller, Ramon; Lozano, Juan Jose; Gines, Pere; Mathurin, Philippe; Sancho-Bru, Pau 分享 收藏
Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis (vol 10, 3126, 2019) Argemi, Josepmaria; Latasa, Maria U.; Atkinson, Stephen R.; Blokhin, Ilya O.; Massey, Veronica; Gue, Joel P.; Cabezas, Joaquin; Lozano, Juan J.; Van Booven, Derek; Bell, Aaron; Cao, Sheng; Vernetti, Lawrence A.; Arab, Juan P.; Ventura-Cots, Meritxell; Edmunds, Lia R.; Fondevila, Constantino; Starkel, Peter; Dubuquoy, Laurent; Louvet, Alexandre; Odena, Gemma; Gomez, Juan L.; Aragon, Tomas; Altamirano, Jose; Caballeria, Juan; Jurczak, Michael J.; Taylor, D. Lansing; Berasain, Carmen; Wahlestedt, Claes; Monga, Satdarshan P.; Morgan, Marsha Y.; Sancho-Bru, Pau; Mathurin, Philippe; Furuya, Shinji; Lackner, Carolin; Rusyn, Ivan; Shah, Vijay H.; Thursz, Mark R.; Mann, Jelena; Avila, Matias A.; Bataller, Ramon 分享 收藏
The outcome of boosting mitochondrial activity in alcohol-associated liver disease is organ-dependent Goikoetxea-Usandizaga, Naroa; Bravo, Miren; Egia-Mendikute, Leire; Abecia, Leticia; Serrano-Macia, Marina; Urdinguio, Rocio G.; Clos-Garcia, Marc; Rodriguez-Agudo, Ruben; Araujo-Legido, Raquel; Lopez-Bermudo, Lucia; Delgado, Teresa C.; Lachiondo-Ortega, Sofia; Gonzalez-Recio, Irene; Gil-Pitarch, Claudia; Pena-Cearra, Ainize; Simon, Jorge; Benede-Ubieto, Raquel; Arino, Silvia; Herranz, Jose M.; Azkargorta, Mikel; Salazar-Bermeo, Julio; Marti, Nuria; Varela-Rey, Marta; Falcon-Perez, Juan M.; Lorenzo, Oscar; Nogueiras, Ruben; Elortza, Felix; Nevzorova, Yulia A.; Cubero, Francisco J.; Saura, Domingo; Martinez-Cruz, Luis Alfonso; Sabio, Guadalupe; Palazon, Asis; Sancho-Bru, Pau; Elguezabal, Natalia; Fraga, Mario F.; Avila, Matias A.; Bataller, Ramon; Marin, Jose J. G.; Martin, Franz; Martinez-Chantar, Maria Luz 分享 收藏
Differential role of MLKL in alcohol-associated and non-alcohol-associated fatty liver diseases in mice and humans (vol 6, e140180, 2021) Miyata, Tatsunori; Wu, Xiaoqin; Fan, Xiude; Huang, Emily; Sanz-Garcia, Carlos; Ross, Christina K. Cajigas-Du; Roychowdhury, Sanjoy; Bellar, Annette; McMullen, Megan R.; Dasarathy, Jaividhya; Allende, Daniela S.; Caballeria, Joan; Sancho-Bru, Pau; McClain, Craig J.; Mitchell, Mack; McCullough, Arthur J.; Radaeva, Svetlana; Barton, Bruce; Szabo, Gyongyi; Dasarathy, Srinivasan; Nagy, Laura E. 分享 收藏
Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure Ma, Jing; Guillot, Adrien; Yang, Zhihong; Mackowiak, Bryan; Hwang, Seonghwan; Park, Ogyi; Peiffer, Brandon J.; Ahmadi, Ali Reza; Melo, Luma; Kusumanchi, Praveen; Huda, Nazmul; Saxena, Romil; He, Yong; Guan, Yukun; Feng, Dechun; Sancho-Bru, Pau; Zang, Mengwei; Cameron, Andrew MacGregor; Bataller, Ramon; Tacke, Frank; Sun, Zhaoli; Liangpunsakul, Suthat; Gao, Bin 分享 收藏
Molecular characterization of chronic liver disease dynamics: From liver fibrosis to acute-on-chronic liver failure Graupera, Isabel; Isus, Laura; Coll, Mar; Pose, Elisa; Diaz, Alba; Vallverdu, Julia; Rubio-Tomas, Teresa; Martinez-Sanchez, Celia; Huelin, Patricia; Llopis, Marta; Sole, Cristina; Sola, Elsa; Fondevila, Constantino; Lozano, Juan Jose; Sancho-Bru, Pau; Gines, Pere; Aloy, Patrick 分享 收藏
The purinergic P2Y14 receptor links hepatocyte death to hepatic stellate cell activation and fibrogenesis in the liver Mederacke, Ingmar; Filliol, Aveline; Affo, Silvia; Nair, Ajay; Hernandez, Celine; Sun, Qiuyan; Hamberger, Florian; Brundu, Francesco; Chen, Yu; Ravichandra, Aashreya; Huebener, Peter; Anke, Helena; Shi, Hongxue; de la Torre, Raquel A. Martinez Garcia; Smith, James R.; Henderson, Neil C.; Vondran, Florian W. R.; Rothlin, Carla, V; Baehre, Heike; Tabas, Ira; Sancho-Bru, Pau; Schwabe, Robert F. 分享 收藏
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