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Anastassis Perrakis

Oncode Institute and Netherlands Cancer Institute

67H指数
335论文数
2.2W被引数
收录论文 90
发表时间
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Halogen bonds between ligands and proteins: Can we use them in validation?配体与蛋白质之间的卤键：我们能否将其用于验证？
errProtein Science
IF5.2
err2025-10-11
err0
errOAAI
errIda de Vries; Georgia Tsiompanaki; Anastassis Perrakis; Robbie P. Joosten
err分享
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DSSP 4: FAIR annotation of protein secondary structureDSSP 4: 蛋白质二级结构的公平注释
errProtein Science
IF5.2
err2025-07-17
err0
errOAAI
errMaarten L. Hekkelman; Daniel Álvarez Salmoral; Anastassis Perrakis; Robbie P. Joosten
err分享
err收藏
Condensin II activation by M18BP1M18BP1对Condensin II的激活
errMolecular Cell
IF16.6
err2025-07-03
err0
errOAAI
errAlessandro Borsellini; Duccio Conti; Erin E. Cutts; Rebecca J. Harris; Kai Walstein; Andrea Graziadei; Valentina Cecatiello; Tom F. Aarts; Ren Xie; Abdelghani Mazouzi; Sushweta Sen; Claire Hoencamp; Richard Pleuger; Sabrina Ghetti; Lina Oberste-Lehn; Dongqing Pan; Tanja Bange; Judith H.I. Haarhuis; Anastassis Perrakis; Thijn R. Brummelkamp; Benjamin D. Rowland; Andrea Musacchio; Alessandro Vannini
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err收藏
Zincore; an atypical coregulator; binds zinc finger transcription factors to control gene expressionZincore；一种非典型协同调节因子；与锌指转录因子结合以控制基因表达
errScience
IF45.8
err2025-07-03
err0
PREAI
errDaniëlle Bianchi; Razvan Borza; Erica De Zan; Guizela Huelsz-Prince; Sebastian Gregoricchio; Marleen Dekker; Alex Fish; Abdelghani Mazouzi; Lona J. Kroese; Simon Linder; Miguel Hernandez-Quiles; Michiel Vermeulen; Patrick H. N. Celie; Paul Krimpenfort; Ji-Ying Song; Wilbert Zwart; Lodewyk Wessels; Sebastian M. B. Nijman; Anastassis Perrakis; Thijn R. Brummelkamp
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Design, Synthesis, and Biological Implications of Autotaxin inhibitors with a Three-Point lock binding mode
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2025-07-01
err0
PREAI
errDesroy, Nicolas; Borza, Razvan; Heiermann, Jorg; Triballeau, Nicolas; Joncour, Agnes; Bienvenu, Natacha; Hengeveld, Willem Jan; Springer, Jasper; Galien, Rene; Joosten, Robbie P.; Perrakis, Anastassis; Heckmann, Bertrand
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JBP1 and JBP3 have conserved structures but different affinity to base-JJBP1和JBP3具有保守结构，但对碱基J的亲和力不同
errJOURNAL OF STRUCTURAL BIOLOGY
IF5.1
err2025-03-01
err0
errOAAI
errde Vries, Ida; Adamopoulos, Athanassios; Kazokaite-Adomaitiene, Justina; Heidebrecht, Tatjana; Fish, Alex; Celie, Patrick H. N.; Joosten, Robbie P.; Perrakis, Anastassis
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Unlocking the signaling potential of GPI-anchored proteins through lipolytic cleavage通过脂解切割释放GPI锚定蛋白的信号传导潜力
errTrends in Cell Biology
IF18.1
err2025-01-22
err0
errOAAI
errRazvan Borza; Elisa Matas-Rico; Anastassis Perrakis; Wouter H. Moolenaar
err分享
err收藏
Decoding microtubule detyrosination: enzyme families, structures, and functional implications
errFEBS LETTERS
IF3
err2024-05-29
err1
errOAAI
errBak, Jitske; Brummelkamp, Thijn R.; Perrakis, Anastassis
err分享
err收藏
Caskin2 is a novel talin- and Abi1-binding protein that promotes cell motility
errJOURNAL OF CELL SCIENCE
IF3.6
err2024-05-16
err0
errOAAI
errWang, Wei; Atherton, Paul; Kreft, Maaike; te Molder, Lisa; van der Poel, Sabine; Hoekman, Liesbeth; Celie, Patrick; Joosten, Robbie P.; Faessler, Reinhard; Perrakis, Anastassis; Sonnenberg, Arnoud
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Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies
errACS CHEMICAL BIOLOGY
IF3.8
err2024-01-17
err1
errOAAI
errAltincekic, Nadide; Joeres, Nathalie; Loehr, Frank; Richter, Christian; Ehrhardt, Claus; Blommers, Marcel J. J.; Berg, Hannes; Oeztuerk, Sare; Gande, Santosh L.; Linhard, Verena; Orts, Julien; Saad, Marie Jose Abi; Buetikofer, Matthias; Kaderli, Janina; Karlsson, B. Goeran; Brath, Ulrika; Hedenstroem, Mattias; Groebner, Gerhard; Sauer, Uwe H.; Perrakis, Anastassis; Langer, Julian; Banci, Lucia; Cantini, Francesca; Fragai, Marco; Grifagni, Deborah; Barthel, Tatjana; Wollenhaupt, Jan; Weiss, Manfred S.; Robertson, Angus; Bax, Adriaan; Sreeramulu, Sridhar; Schwalbe, Harald
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Challenges and opportunities in macromolecular structure determination
errNATURE REVIEWS MOLECULAR CELL BIOLOGY
IF90.2
err2023-10-17
err2
PREAI
errBai, Xiao-chen; Gonen, Tamir; Gronenborn, Angela M.; Perrakis, Anastassis; Thorn, Andrea; Yang, Jianyi
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err收藏
Distant sequence regions of JBP1 contribute to J-DNA binding
errLIFE SCIENCE ALLIANCE
IF2.9
err2023-06-16
err1
errOAAI
errde Vries, Ida; Ammerlaan, Danique; Heidebrecht, Tatjana; Celie, Patrick H. N.; Geerke, Daan P.; Joosten, Robbie P.; Perrakis, Anastassis
err分享
err收藏
Autotaxin facilitates selective LPA receptor signaling
errCELL CHEMICAL BIOLOGY
IF7.2
err2023-01-01
err20
errOAAI
errPolo, Fernando Salgado-; Borza, Razvan; Matsoukas, Minos-Timotheo; Marsasis, Florence; Jagerschmid, Catherine; Waeckel, Ludovic; Moolenaar, Wouter H.; Ford, Paul; Heckmann, Bertrand; Perrakis, Anastassis
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Crystal structure of the phospholipase A and acyltransferase 4 (PLAAT4) catalytic domain
errJOURNAL OF STRUCTURAL BIOLOGY
IF5.1
err2022-12-01
err1
errOAAI
errWehlin, Anna; Cornaciu, Irina; Marquez, Jose Antonio; Perrakis, Anastassis; Castelmur, Eleonore von
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AlphaFill: enriching AlphaFold models with ligands and cofactors
errNATURE METHODS
IF32.1
err2022-11-24
err204
errOAAI
errHekkelman, Maarten L.; de Vries, Ida; Joosten, Robbie P.; Perrakis, Anastassis
err分享
err收藏
Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and DynactinSpindly适配器的构象转变是其与dynetin和Dynactin相互作用的基础
errJOURNAL OF CELL BIOLOGY
IF6.4
err2022-09-15
err7
errOAAI
errD'Amico, Ennio A.; Ahmad, Misbha Ud Din; Cmentowski, Verena; Girbig, Mathias; Mueller, Franziska; Wohlgemuth, Sabine; Brockmeyer, Andreas; Maffini, Stefano; Janning, Petra; Vetter, Ingrid R.; Carter, Andrew P.; Perrakis, Anastassis; Musacchio, Andrea
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A type IV Autotaxin inhibitor ameliorates acute liver injury and nonalcoholic steatohepatitis
errEMBO MOLECULAR MEDICINE
IF8.3
err2022-07-14
err11
errOAAI
errBooijink, Richell; Salgado-Polo, Fernando; Jamieson, Craig; Perrakis, Anastassis; Bansal, Ruchi
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err收藏
Structure-Based Design of a Novel Class of Autotaxin InhibitorsBased on Endogenous Allosteric Modulators基于内源性变构调节剂的新型自分泌运动抑制剂的基于结构的设计
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2022-04-20
err14
errOAAI
errClark, Jennifer M.; Salgado-Polo, Fernando; Macdonald, Simon J. F.; Barrett, Tim N.; Perrakis, Anastassis; Jamieson, Craig
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err收藏
Structure and function of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family: Tidying up diversity
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-02-01
err75
errOAAI
errBorza, Razvan; Salgado-Polo, Fernando; Moolenaar, Wouter H.; Perrakis, Anastassis
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err收藏
A novel mechanism of autotaxin-mediated cell signaling that is independent of catalytic activity and inhibited by ziritaxestat
errEUROPEAN RESPIRATORY JOURNAL
IF21
err2021-11-25
err0
PREAI
errSalgado-Polo, Fernando; Borza, Razvan; Ford, Paul; Heckmann, Bertrand; Perrakis, Anastassis
err分享
err收藏

研究方向

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合作学者
合作期刊
P
Piet Borst
H 指数: 134 · 论文数: 621
A
Albert J. R. Heck
H 指数: 132 · 论文数: 1.2K
J
Jos H. Beijnen
H 指数: 129 · 论文数: 1.8K
D
David I. Stuart
H 指数: 129 · 论文数: 1.1K
J
John A. Tainer
H 指数: 123 · 论文数: 807
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