Chris G. Parsons - Publications, H-index & Citations

Chris G. Parsons

merz pharmaceuticals gmbh

49H指数

182论文数

1.1W被引数

收录论文 45

发表时间

GAL-201 as a Promising Amyloid-β-Targeting Small-Molecule Approach for Alzheimer's Disease Treatment: Consistent Effects on Synaptic Plasticity, Behavior and Neuroinflammation GAL-201作为一种有前景的靶向淀粉样β蛋白的小分子方法用于阿尔茨海默病治疗：对突触可塑性、行为和神经炎症具有一致的作用

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IF4.9

2025-04-28

OAAI

Riemann, Katrin; von Ahsen, Jeldrik; Boehm, Tamara; Schlegel, Martin; Kreuzer, Matthias; Fenzl, Thomas; Russ, Hermann; Parsons, Christopher G.; Rammes, Gerhard

Inhalational Anesthetics Do Not Deteriorate Amyloid-β-Derived Pathophysiology in Alzheimer's Disease: Investigations on the Molecular, Neuronal, and Behavioral Level

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2021-11-23

PREAI

Hofmann, Carolin; Sander, Annika; Wang, Xing Xing; Buerge, Martina; Jungwirth, Bettina; Borgstedt, Laura; Kreuzer, Matthias; Kopp, Claudia; Schorpp, Kenji; Hadian, Kamyar; Wotjak, Carsten T.; Ebert, Tim; Ruitenberg, Maarten; Parsons, Christopher G.; Rammes, Gerhard

Do podcasts improve the learning experience of dyslexic medical

EUROPEAN PSYCHIATRY

IF6.7

2021-08-13

OAAI

Parsons, C.

Preclinical to phase II amyloid beta (A) peptide modulators under investigation for Alzheimer's disease

EXPERT OPINION ON INVESTIGATIONAL DRUGS

IF4.1

2017-04-24

PREAI

Parsons, Chris G.; Rammes, Gerhard

Brain concentrations of mGluR5 negative allosteric modulator MTEP in relation to receptor occupancy - Comparison to MPEP mGluR5负变构调节剂MTEP的脑浓度与受体占有率的关系-与MPEP的比较

PHARMACOLOGICAL REPORTS

IF3.8

2015-06-01

PREAI

Nagel, Jens; Greco, Sergio; Parsons, Chris G.; Flik, Gunnar; Tober, Carsten; Klein, Kai-Uwe; Danysz, Wojciech

Effects of sarizotan in animal models of ADHD: challenging pharmacokinetic-pharmacodynamic relationships

JOURNAL OF NEURAL TRANSMISSION

IF4

2015-03-22

PREAI

Danysz, Wojciech; Flik, Gunnar; McCreary, Andrew; Tober, Carsten; Dimpfel, Wilfried; Bizot, Jean C.; Kostrzewa, Richard; Brown, Russell W.; Jatzke, Claudia C.; Greco, Sergio; Jenssen, Ann-Kristin; Parsons, Christopher G.

Rationale for combining glutamatergic and cholinergic approaches in the symptomatic treatment of Alzheimer's disease

EXPERT REVIEW OF NEUROTHERAPEUTICS

IF3.4

2014-01-09

OAAI

Francis, Paul T.; Parsons, Chris G.; Jones, Roy W.

GluN2A and GluN2B NMDA Receptor Subunits Differentially Modulate Striatal Output Pathways and Contribute to Levodopa-Induced Abnormal Involuntary Movements in Dyskinetic Rats

ACS CHEMICAL NEUROSCIENCE

IF3.9

2013-04-23

OAAI

Mabrouk, Omar S.; Mela, Flora; Calcagno, Mariangela; Budri, Mirco; Viaro, Riccardo; Dekundy, Andrzej; Parsons, Christopher G.; Auberson, Yves P.; Morari, Michele

Alzheimer's disease, β-amyloid, glutamate, NMDA receptors and memantine - searching for the connections

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2012-08-22

460

OAAI

Danysz, Wojciech; Parsons, Chris G.

Effects of memantine and MK-801 on NMDA-induced currents in cultured neurones and on synaptic transmission and LTP in area CA1 of rat hippocampal slices

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2012-07-19

128

OAAI

Frankiewicz, T; Potier, B; Bashir, ZI; Collingridge, GL; Parsons, CG

Effects of memantine on recombinant rat NMDA receptors expressed in HEK 293 cells

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2012-07-19

105

OAAI

Bresink, I; Benke, TA; Collett, VJ; Seal, AJ; Parsons, CG; Henley, JM; Collingridge, GL

Interactions of 2,3-benzodiazepines and cyclothiazide at AMPA receptors: Patch clamp recordings in cultured neurones and area CA1 in hippocampal slices

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2012-07-19

OAAI

Rammes, G; Swandulla, D; Collingridge, GL; Hartmann, S; Parsons, CG

Impact of lipid raft integrity on GABAA receptor function and its modulation by benzodiazepines

PHARMACOPSYCHIATRY

IF2.2

2011-09-29

PREAI

Nothdurfter, C.; Tanasic, S.; Di Benedetto, B.; Uhr, M.; Kessler, J.; Wagner, E. M.; Gilling, K.; Parsons, C.; Rein, T.; Holsboer, F.; Rupprecht, R.; Rammes, G.

Pharmacological characterization of MRZ-8676, a novel negative allosteric modulator of subtype 5 metabotropic glutamate receptors (mGluR5): focus on L-DOPA-induced dyskinesia

JOURNAL OF NEURAL TRANSMISSION

IF4

2010-12-16

PREAI

Dekundy, Andrzej; Gravius, Andreas; Hechenberger, Mirko; Pietraszek, Malgorzata; Nagel, Jens; Tober, Carsten; van der Elst, Martine; Mela, Flora; Parsons, Christopher G.; Danysz, Wojciech

In vivo evidence for functional NMDA receptor blockade by memantine in rat hippocampal neurons

JOURNAL OF NEURAL TRANSMISSION

IF4

2010-09-07

PREAI

Szegedi, Viktor; Juhasz, Gabor; Parsons, Chris G.; Budai, Denes

Synergism of virtual screening and medicinal chemistry: Identification and optimization of allosteric antagonists of metabotropic glutamate receptor 1

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2009-08-01

PREAI

Noeske, Tobias; Trifanova, Dina; Kauss, Valerjans; Renner, Steffen; Parsons, Christopher G.; Schneider, Gisbert; Weil, Tanja

Blocking kinetics of memantine on NR1a/2A receptors recorded in inside-out and outside-out patches from Xenopus oocytes

JOURNAL OF NEURAL TRANSMISSION

IF4

2008-07-08

PREAI

Parsons, Chris G.; Gilling, Kate E.; Jatzke, Claudia

Memantine does not show intracellular block of the NMDA receptor channel

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2008-06-01

PREAI

Parsons, Chris G.; Gilling, Kate E.; Jatzke, Claudia

The fraction of activated N-methyl-D-aspartate receptors during synaptic transmission remains constant in the presence of the glutamate release inhibitor riluzole

JOURNAL OF NEURAL TRANSMISSION

IF4

2008-05-21

OAAI

Rammes, G.; Zieglgaensberger, W.; Parsons, C. G.

Positive and negative modulation of group I metabotropic glutamate receptors

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2008-01-04

PREAI

Vanejevs, Maksims; Jatzke, Claudia; Renner, Steffen; Mueller, Sibylle; Hechenberger, Mirko; Bauer, Tania; Klochkova, Anna; Pyatkin, Ilya; Kazyulkin, Denis; Aksenova, Elena; Shulepin, Sergey; Timonina, Olga; Haasis, Ariane; Gutcaits, Aleksandrs; Parsons, Christopher G.; Kauss, Valerjans; Weil, Tania

研究方向