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M

Marzena Pazgier

uniformed services university of the health sciences
H指数:44
被引数:6,616

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The asymmetric opening of HIV-1 Env by a potent CD4 mimetic enables anti-coreceptor binding site antibodies to mediate ADCC

HIV-1 Env的对称性开启由一种强效的CD4模拟物实现，这使抗共受体结合位点抗体能够介导ADCC。

Nature Communications
IF15.7
2025-12-010
OAAI
Jonathan Richard; Michael W. Grunst; Ling Niu; Marco A. Díaz-Salinas; Li Zhu; William D. Tolbert; Lorie Marchitto; Fei Zhou; Catherine Bourassa; Hongil Kim; Sri Lakshmi Tejaswi Boodapati; Derek Yang; Ta Jung Chiu; Hung-Ching Chen; Mehdi Benlarbi; Guillaume Beaudoin-Bussières; Suneetha Gottumukkala; Wenwei Li; Katrina Dionne; Étienne Bélanger; Debashree Chatterjee; Halima Medjahed; Wayne A. Hendrickson; Joseph Sodroski; Zabrina C. Lang; Abraham J. Morton; Rick K. Huang; Doreen Matthies; Amos B. Smith; Priti Kumar; Walther Mothes; James B. Munro; Marzena Pazgier; Andrés Finzi
Conformational dynamics of the HIV-1 envelope glycoprotein from CRF01_AE is associated with susceptibility to antibody-dependent cellular cytotoxicity

CRF01_AE型HIV-1包膜糖蛋白的构象动力学与抗体依赖性细胞介导的细胞毒性敏感性相关

JOURNAL OF VIROLOGY
IF3.8
2025-12-010
PRE
Diaz-Salinas, Marco A.; Benlarbi, Mehdi; Chatterjee, Debashree; Nayrac, Manon; Robidas, Megane; Pinyakorn, Suteeraporn; Phanuphak, Nittiya; Sacdalan, Carlo; Medjahed, Halima; Prevost, Jeremie; Trautmann, Lydie; Pazgier, Marzena; Finzi, Andres; Munro, James B.
Optimization of VE607 to generate analogs with improved neutralization activities against SARS-CoV-2 variants

VE607优化以生成对SARS-CoV-2变体具有增强中和活性的类似物

JOURNAL OF VIROLOGY
IF3.8
2025-10-010
PRE
Ding, Shilei; Yang, Derek; Ullah, Irfan; Niu, Ling; Unger, Matthew; Diaz-Salinas, Marco A.; Chandravanshi, Monika; Zhou, Fei; Beaudoin-Bussieres, Guillaume; Benlarbi, Mehdi; Tolbert, William D.; Yoon, Keon-Woong; Xu, Ruixue; Laroche, Genevieve; Gaudette, Fleur; Morton, Abraham J.; Lang, Zabrina C.; Son, Anna; Abrams, Cameron; Cote, Marceline; Smith III, Amos B.; Huang, Rick K.; Matthies, Doreen; Munro, James B.; Pazgier, Marzena; Uchil, Pradeep D.; Finzi, Andres
A comprehensive engineering strategy improves potency and manufacturability of a near pan-neutralizing antibody against HIV

一项全面的工程策略提高了针对HIV的近全中和抗体的效力和可制造性。

Structure
IF4.3
2025-05-140
OA
Mohammad M. Sajadi; Abdolrahim Abbasi; Zahra Rikhtegaran Tehrani; Christine Siska; Rutilio Clark; Woo Chi; Michael S. Seaman; Dieter Mielke; Kshitij Wagh; Qingbo Liu; Taylor Jumpa; Randal R. Ketchem; Dung N. Nguyen; William D. Tolbert; Brian G. Pierce; Ben Atkinson; Derrick Deming; Megan Sprague; Andrew Asakawa; David Ferrer; Yasmin Dunn; Sarah Calvillo; Rui Yin; Johnathan D. Guest; Bette Korber; Bryan T. Mayer; Alicia H. Sato; Xin Ouyang; Scott Foulke; Parham Habibzadeh; Maryam Karimi; Arash Aslanabadi; Mahsa Hojabri; Saman Saadat; Roza Zareidoodeji; Mateusz Kędzior; Edwin Pozharski; Alonso Heredia; Hegang Chen; David Montefiori; Guido Ferrari; Marzena Pazgier; George K. Lewis; Joseph G. Jardine; Paolo Lusso; Anthony DeVico
Safety, pharmacokinetics, and biological activity of CD4-mimetic BNM-III-170 in SHIV-infected rhesus macaques
JOURNAL OF VIROLOGY
IF3.8
2025-04-010
OAAI
Viox, Elise G.; Richard, Jonathan; Grandea, Andres G., III; Nguyen, Kevin; Harper, Justin; Auger, James; Ding, Shilei; Gasser, Romain; Prevost, Jeremie; Marchitto, Lorie; Medjahed, Halima; Bourassa, Catherine; Gaudette, Fleur; Pagliuzza, Amelie; Trifone, Cesar Ariel; Gavegnano, Christina; Hurwitz, Selwyn J.; Park, Jun; Clark, Natasha M.; Hammad, Iman; Capuano III, Saverio; Martin, Malcolm A.; Schinazi, Raymond F.; Silvestri, Guido; Kulpa, Deanna A.; Kumar, Priti; Chomont, Nicolas; Pazgier, Marzena; Smith III, Amos B.; Sodroski, Joseph; Evans, David T.; Finzi, Andres; Paiardini, Mirko
The combination of three CD4-induced antibodies targeting highly conserved Env regions with a small CD4-mimetic achieves potent ADCC activity
JOURNAL OF VIROLOGY
IF3.8
2024-10-220
PRE
Marchitto, Lorie; Richard, Jonathan; Prevost, Jeremie; Tauzin, Alexandra; Yang, Derek; Chiu, Ta-Jung; Chen, Hung-Ching; Diaz-Salinas, Marco A.; Nayrac, Manon; Benlarbi, Mehdi; Beaudoin-Bussieres, Guillaume; Anand, Sai Priya; Dionne, Katrina; Belanger, Etienne; Chatterjee, Debashree; Medjahed, Halima; Bourassa, Catherine; Tolbert, William D.; Hahn, Beatrice H.; Munro, James B.; Pazgier, Marzena; Smith III, Amos B.; Finzi, Andres
Three families of CD4-induced antibodies are associated with the capacity of plasma from people living with HIV to mediate ADCC in the presence of CD4-mimetics

CD4-induced抗体的三个家族与HIV感染者血浆在存在CD4-mimetics的情况下介导ADCC的能力有关。

JOURNAL OF VIROLOGY
IF3.8
2024-10-222
OA
Tauzin, Alexandra; Marchitto, Lorie; Belanger, Etienne; Benlarbi, Mehdi; Beaudoin-Bussieres, Guillaume; Prevost, Jeremie; Yang, Derek; Chiu, Ta-Jung; Chen, Hung-Ching; Bourassa, Catherine; Medjahed, Halima; Korzeniowski, Marek K.; Gottumukkala, Suneetha; Tolbert, William D.; Richard, Jonathan; Smith III, Amos B.; Pazgier, Marzena; Finzi, Andres
Immune response profiles from humans experimentally exposed to Phlebotomus duboscqi bites

实验暴露于Phlebotomus duboscqi叮咬的人类的免疫反应概况

FRONTIERS IN IMMUNOLOGY
IF5.9
2024-04-031
OAAI
de Araujo, Fernanda Fortes; Abdeladhim, Maha; Teixeira, Clarissa; Hummer, Kelly; Wilkerson, Matthew D.; Ressner, Roseanne; Lakhal-Naouar, Ines; Ellis, Michael W.; Meneses, Claudio; Nurmukhambetova, Saule; Gomes, Regis; Tolbert, W. David; Turiansky, George W.; Pazgier, Marzena; Oliveira, Fabiano; Valenzuela, Jesus G.; Kamhawi, Shaden; Aronson, Naomi
Plasma Human Immunodeficiency Virus 1 Soluble Glycoprotein 120 Association With Correlates of Immune Dysfunction and Inflammation in Antiretroviral Therapy-Treated Individuals With Undetectable Viremia
JOURNAL OF INFECTIOUS DISEASES
IF4.5
2023-11-306
OAAI
Benlarbi, Mehdi; Richard, Jonathan; Bourassa, Catherine; Tolbert, William D.; Chartrand-Lefebvre, Carl; Gendron-Lepage, Gabrielle; Sylla, Mohamed; El-Far, Mohamed; Messier-Peet, Marc; Guertin, Camille; Turcotte, Isabelle; Fromentin, Remi; Verly, Myriam Maude; Prevost, Jeremie; Clark, Andrew; Mothes, Walther; Kaufmann, Daniel E.; Maldarelli, Frank; Chomont, Nicolas; Begin, Philippe; Tremblay, Cecile; Baril, Jean-Guy; Trottier, Benoit; Trottier, Sylvie; Duerr, Ralf; Pazgier, Marzena; Durand, Madeleine; Finzi, Andres
Piperidine CD4-Mimetic Compounds Expose Vulnerable Env Epitopes Sensitizing HIV-1-Infected Cells to ADCC

哌啶CD4-Mimetic化合物暴露脆弱的Env表位，使HIV-1-Infected细胞对ADCC敏感

VIRUSES-BASEL
IF3.5
2023-05-176
OAAI
Ding, Shilei; Tolbert, William D.; Zhu, Huile; Lee, Daniel; Marchitto, Lorie; Higgins, Tyler; Zhao, Xuchen; Nguyen, Dung; Sherburn, Rebekah; Richard, Jonathan; Gendron-Lepage, Gabrielle; Medjahed, Halima; Mohammadi, Mohammadjavad; Abrams, Cameron; Pazgier, Marzena; Smith, Amos B., III; Finzi, Andres

研究方向

暂未获取到该数据
W
William D. Tolbert
H 指数:32论文数:164被引数:2,792
A
Andrés Finzi
H 指数:60论文数:317被引数:1.3万
J
Jérémie Prévost
H 指数:40论文数:138被引数:5,489
J
Jonathan Richard
H 指数:46论文数:179被引数:6,493
S
Shilei Ding
H 指数:39论文数:128被引数:4,850
H
Halima Medjahed
H 指数:34论文数:185被引数:4,342
A
Amos B. Smith
H 指数:95论文数:1,150被引数:4.0万
G
George K. Lewis
H 指数:48论文数:331被引数:1.3万
M
Mehdi Benlarbi
H 指数:22论文数:83被引数:2,474
Wuyuan Lu 封面图
Wuyuan Lu
H 指数:62论文数:204被引数:1.1万