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Inhibitory effects of molnupiravir on Crimean-Congo hemorrhagic fever virus polymerase 莫纳皮拉韦对克里米亚-刚果出血热病毒聚合酶的抑制作用 Sloan, Angela; Gordon, Calvin J.; Prevost, Jeremie; Audet, Jonathan; Fulton, Kathleen; Woolner, Emma; Chang, Ming-Hao; Walker, Simon M.; Tchesnokov, Egor P.; Das, Kalyan; Safronetz, David; Gotte, Matthias 分享 收藏
Conformational dynamics of the HIV-1 envelope glycoprotein from CRF01_AE is associated with susceptibility to antibody-dependent cellular cytotoxicity CRF01_AE型HIV-1包膜糖蛋白的构象动力学与抗体依赖性细胞介导的细胞毒性敏感性相关 Diaz-Salinas, Marco A.; Benlarbi, Mehdi; Chatterjee, Debashree; Nayrac, Manon; Robidas, Megane; Pinyakorn, Suteeraporn; Phanuphak, Nittiya; Sacdalan, Carlo; Medjahed, Halima; Prevost, Jeremie; Trautmann, Lydie; Pazgier, Marzena; Finzi, Andres; Munro, James B. 分享 收藏
CD4+and CD8+Tcells are not the main driver of Lassa fever pathogenesis in macaques CD4+和CD8+T细胞不是导致恒河猴拉沙热发病机制的主要驱动因素。 Prevost, Jeremie; Tailor, Nikesh; Soule, Geoff; Audet, Jonathan; Deschambault, Yvon; Vendramelli, Robert; Prado-Smith, Jessica; Tierney, Kevin; Azaransky, Kimberly; Kobasa, Darwyn; Clancy, Chad S.; Feldmann, Heinz; Rosenke, Kyle; Safronetz, David 分享 收藏
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Assessing the Potential of Sexual Transmission of Lassa Virus in a Natural Rodent Reservoir 评估拉沙病毒通过性传播在自然啮齿动物宿主中的潜力 Prevost, Jeremie; Tailor, Nikesh; Soule, Geoff; Frost, Kathy; Azaransky, Kimberly; Tierney, Kevin; Feldmann, Heinz; Booth, Stephanie; Rosenke, Kyle; Safronetz, David 分享 收藏
Safety, pharmacokinetics, and biological activity of CD4-mimetic BNM-III-170 in SHIV-infected rhesus macaques Viox, Elise G.; Richard, Jonathan; Grandea, Andres G., III; Nguyen, Kevin; Harper, Justin; Auger, James; Ding, Shilei; Gasser, Romain; Prevost, Jeremie; Marchitto, Lorie; Medjahed, Halima; Bourassa, Catherine; Gaudette, Fleur; Pagliuzza, Amelie; Trifone, Cesar Ariel; Gavegnano, Christina; Hurwitz, Selwyn J.; Park, Jun; Clark, Natasha M.; Hammad, Iman; Capuano III, Saverio; Martin, Malcolm A.; Schinazi, Raymond F.; Silvestri, Guido; Kulpa, Deanna A.; Kumar, Priti; Chomont, Nicolas; Pazgier, Marzena; Smith III, Amos B.; Sodroski, Joseph; Evans, David T.; Finzi, Andres; Paiardini, Mirko 分享 收藏
A gp41 HR2 residue modulates the susceptibility of HIV-1 envelope glycoproteins to small molecule inhibitors targeting gp120 Chatterjee, Debashree; Niu, Ling; Medjahed, Halima; Ding, Shilei; Benlarbi, Mehdi; Belanger, Etienne; Prevost, Jeremie; Chen, Hung-Ching; Tolbert, William D.; Smith III, Amos B.; Pazgier, Marzena; Finzi, Andres 分享 收藏
Dissecting immunological mechanisms underlying influenza viral nucleoprotein-induced mucosal immunity against diverse viral strains Zhang, Wanyue; Sloan, Angela; Prevost, Jeremie; Tamming, Levi; Raman, Sathya; Pfeifle, Annabelle; Gravel, Caroline; Chen, Wangxue; Hashem, Anwar M.; Wu, Jianguo; Cao, Jingxin; Johnston, Michael J. W.; Wang, Lisheng; Sauve, Simon; Rosu-Myles, Michael; Kobasa, Darwyn; Safronetz, David; Li, Xuguang 分享 收藏
CD4 downregulation precedes Env expression and protects HIV-1-infected cells from ADCC mediated by non-neutralizing antibodies Richard, Jonathan; Sannier, Geremy; Zhu, Li; Prevost, Jeremie; Marchitto, Lorie; Benlarbi, Mehdi; Beaudoin-Bussieres, Guillaume; Kim, Hongil; Sun, Yaping; Chatterjee, Debashree; Medjahed, Halima; Bourassa, Catherine; Delgado, Gloria-Gabrielle; Dube, Mathieu; Kirchhoff, Frank; Hahn, Beatrice H.; Kumar, Priti; Kaufmann, Daniel E.; Finzi, Andres 分享 收藏
The combination of three CD4-induced antibodies targeting highly conserved Env regions with a small CD4-mimetic achieves potent ADCC activity Marchitto, Lorie; Richard, Jonathan; Prevost, Jeremie; Tauzin, Alexandra; Yang, Derek; Chiu, Ta-Jung; Chen, Hung-Ching; Diaz-Salinas, Marco A.; Nayrac, Manon; Benlarbi, Mehdi; Beaudoin-Bussieres, Guillaume; Anand, Sai Priya; Dionne, Katrina; Belanger, Etienne; Chatterjee, Debashree; Medjahed, Halima; Bourassa, Catherine; Tolbert, William D.; Hahn, Beatrice H.; Munro, James B.; Pazgier, Marzena; Smith III, Amos B.; Finzi, Andres 分享 收藏
Three families of CD4-induced antibodies are associated with the capacity of plasma from people living with HIV to mediate ADCC in the presence of CD4-mimetics CD4-induced抗体的三个家族与HIV感染者血浆在存在CD4-mimetics的情况下介导ADCC的能力有关。 Tauzin, Alexandra; Marchitto, Lorie; Belanger, Etienne; Benlarbi, Mehdi; Beaudoin-Bussieres, Guillaume; Prevost, Jeremie; Yang, Derek; Chiu, Ta-Jung; Chen, Hung-Ching; Bourassa, Catherine; Medjahed, Halima; Korzeniowski, Marek K.; Gottumukkala, Suneetha; Tolbert, William D.; Richard, Jonathan; Smith III, Amos B.; Pazgier, Marzena; Finzi, Andres 分享 收藏
Sustained IFN signaling is associated with delayed development of SARS-CoV-2-specific immunity 持续的IFN信号传导与SARS-CoV-2-specific免疫的延迟发展有关 Brunet-Ratnasingham, Elsa; Morin, Sacha; Randolph, Haley E.; Labrecque, Marjorie; Belair, Justin; Lima-Barbosa, Raphael; Pagliuzza, Amelie; Marchitto, Lorie; Hultstrom, Michael; Niessl, Julia; Cloutier, Rose; Flores, Alina M. Sreng; Brassard, Nathalie; Benlarbi, Mehdi; Prevost, Jeremie; Ding, Shilei; Anand, Sai Priya; Sannier, Geremy; Marks, Amanda; Wagsaeter, Dick; Bareke, Eric; Zeberg, Hugo; Lipcsey, Miklos; Frithiof, Robert; Larsson, Anders; Zhou, Sirui; Nakanishi, Tomoko; Morrison, David; Vezina, Dani; Bourassa, Catherine; Gendron-Lepage, Gabrielle; Medjahed, Halima; Point, Floriane; Richard, Jonathan; Larochelle, Catherine; Prat, Alexandre; Cunningham, Janet L.; Arbour, Nathalie; Durand, Madeleine; Richards, J. Brent; Moon, Kevin; Chomont, Nicolas; Finzi, Andres; Tetreault, Martine; Barreiro, Luis; Wolf, Guy; Kaufmann, Daniel E. 分享 收藏
Plasma Human Immunodeficiency Virus 1 Soluble Glycoprotein 120 Association With Correlates of Immune Dysfunction and Inflammation in Antiretroviral Therapy-Treated Individuals With Undetectable Viremia Benlarbi, Mehdi; Richard, Jonathan; Bourassa, Catherine; Tolbert, William D.; Chartrand-Lefebvre, Carl; Gendron-Lepage, Gabrielle; Sylla, Mohamed; El-Far, Mohamed; Messier-Peet, Marc; Guertin, Camille; Turcotte, Isabelle; Fromentin, Remi; Verly, Myriam Maude; Prevost, Jeremie; Clark, Andrew; Mothes, Walther; Kaufmann, Daniel E.; Maldarelli, Frank; Chomont, Nicolas; Begin, Philippe; Tremblay, Cecile; Baril, Jean-Guy; Trottier, Benoit; Trottier, Sylvie; Duerr, Ralf; Pazgier, Marzena; Durand, Madeleine; Finzi, Andres 分享 收藏
Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir Prevost, Jeremie; Chen, Yaozong; Zhou, Fei; Tolbert, William D.; Gasser, Romain; Medjahed, Halima; Nayrac, Manon; Nguyen, Dung N.; Gottumukkala, Suneetha; Hessell, Ann J.; Rao, Venigalla B.; Pozharski, Edwin; Huang, Rick K.; Matthies, Doreen; Finzi, Andres; Pazgier, Marzena 分享 收藏
Impact of HIV-1 Vpu-mediated downregulation of CD48 on NK-cell-mediated antibody-dependent cellular cytotoxicity HIV-1 Vpu介导的CD48下调对NK细胞介导的抗体依赖性细胞毒性的影响 Marchitto, Lorie; Benlarbi, Mehdi; Prevost, Jeremie; Laumaea, Annemarie; Descoteaux-Dinelle, Jade; Medjahed, Halima; Bourassa, Catherine; Gendron-Lepage, Gabrielle; Kirchhoff, Frank; Sauter, Daniel; Hahn, Beatrice H.; Finzi, Andres; Richard, Jonathan 分享 收藏
Temsavir blocks the immunomodulatory activities of HIV-1 soluble gp120 Richard, Jonathan; Prevost, Jeremie; Bourassa, Catherine; Brassard, Nathalie; Boutin, Marianne; Benlarbi, Mehdi; Goyette, Guillaume; Medjahed, Halima; Gendron-Lepage, Gabrielle; Gaudette, Fleur; Chen, Hung-Ching; Tolbert, William D.; Smith, Amos B., III; Pazgier, Marzena; Dube, Mathieu; Clark, Andrew; Mothes, Walther; Kaufmann, Daniel E.; Finzi, Andres 分享 收藏
Characterization of a Novel CD4 Mimetic Compound YIR-821 against HIV-1 Clinical Isolates 抗HIV-1临床分离株的新型CD4模拟化合物YIR-821的表征 Matsumoto, Kaho; Kuwata, Takeo; Tolbert, William D.; Richard, Jonathan; Ding, Shilei; Prevost, Jeremie; Takahama, Shokichi; Judicate, George P.; Ueno, Takamasa; Nakata, Hirotomo; Kobayakawa, Takuya; Tsuji, Kohei; Tamamura, Hirokazu; Smith, Amos B., III; Pazgier, Marzena; Finzi, Andres; Matsushita, Shuzo 分享 收藏
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