Helen M. E. Duyvesteyn - Publications, H-index & Citations

Helen M. E. Duyvesteyn

university of oxford

30H指数

91论文数

8.4K被引数

收录论文 28

发表时间

Structural and functional mapping of protective human monoclonal antibodies against enterovirus A71 肠道病毒A71的保护性人源单克隆抗体的结构及功能分析

Science Advances

IF12.5

2026-06-05

OAAI

Daming Zhou; Abhay Kotecha; James T. Kelly; Peng-Nien Huang; Yi-Yin Chen; Thomas S. Walter; Helen M.E. Duyvesteyn; Raymond J. Owens; Shu-Yuan Ho; Tzou-Yien Lin; Elizabeth E. Fry; Jingshan Ren; Kuan-Ying A. Huang; David I. Stuart

Cattle antibodies identify a cross-serotype broadly neutralising foot-and-mouth disease virus epitope 牛抗体识别跨血清型广泛中和口蹄疫病毒的表位

npj Vaccines

IF6.5

2026-04-02

OAAI

Marie Bonnet-Di Placido; Helen M. E. Duyvesteyn; Angela W. Steyn; Abigail L. Hay; Claudine Porta; Kristel Ramirez Valdez; Elena Lokhman; Sylvia Crossley; Kevan Hanson; William N. Mwangi; Danish Munir; Eva Perez-Martin; Nick J. Knowles; Alison Burman; Abdelaziz A. Yassin; Amin Asfor; Cristina Faralla; Katherine J. Lam; Róisín McComb; Carina Leifeld; Kimberly Pietersz; Donald P. King; Erwin van den Born; Sherie K. Duncan; Bryan Charleston; Elizabeth E. Fry; Jingshan Ren; David I. Stuart; John A. Hammond

Author Correction: An RBD-Fc mucosal vaccine provides variant-proof protection against SARS-CoV-2 in mice and hamsters 作者更正: rbd-fc粘膜疫苗在小鼠和仓鼠中提供了针对SARS-CoV-2的防变异保护

npj Vaccines

IF6.5

2025-07-10

OAAI

Yanjun Zhang; Yan Wu; Meng-Qian Zhang; Haiyue Rao; Zhaoyong Zhang; Xiangyue He; Yiwen Liang; Raoqing Guo; Yaochang Yuan; Jing Sun; Helen M. E. Duyvesteyn; Elizabeth E. Fry; David I. Stuart; Jingxian Zhao; XiaoYan Pan; Shu-Lin Liu; Jincun Zhao; Jiandong Huo

An RBD-Fc mucosal vaccine provides variant-proof protection against SARS-CoV-2 in mice and hamsters RBD-Fc黏膜疫苗在 mice 和 hamsters 中提供针对 SARS-CoV-2 的抗变异株保护作用

NPJ VACCINES

IF6.5

2025-05-18

OAAI

Zhang, Yanjun; Wu, Yan; Zhang, Meng-Qian; Rao, Haiyue; Zhang, Zhaoyong; He, Xiangyue; Liang, Yiwen; Guo, Raoqing; Yuan, Yaochang; Sun, Jing; Duyvesteyn, Helen M. E.; Fry, Elizabeth E.; Stuart, David I.; Zhao, Jingxian; Zhao, Jincun

A monoclonal antibody targeting the Nipah virus fusion glycoprotein apex imparts protection from disease

JOURNAL OF VIROLOGY

IF3.8

2024-10-22

PREAI

Avanzato, Victoria A.; Bushmaker, Trenton; Oguntuyo, Kasopefoluwa Y.; Yinda, Claude Kwe; Duyvesteyn, Helen M. E.; Stass, Robert; Meade-White, Kimberly; Rosenke, Rebecca; Thomas, Tina; van Doremalen, Neeltje; Saturday, Greg; Doores, Katie J.; Lee, Benhur; Bowden, Thomas A.; Munster, Vincent J.

A broadly reactive ultralong bovine antibody that can determine the integrity of foot- and- mouth disease virus capsids

JOURNAL OF GENERAL VIROLOGY

IF4.3

2024-10-18

PREAI

Clarke, John D.; Duyvesteyn, Helen M. E.; Perez-Martin, Eva; Latisenko, Undine; Porta, Claudine; Humphreys, Kathleen V.; Hay, Abigail L.; Ren, Jingshan; Fry, Elizabeth E.; van den Born, Erwin; Charleston, Bryan; Bonnet-Di Placido, Marie; Owens, Raymond J.; Stuart, David I.; Hammond, John A.

Structural insights into Frizzled3 through nanobody modulators

NATURE COMMUNICATIONS

IF15.7

2024-08-22

OAAI

Hillier, James; Zhao, Yuguang; Carrique, Loic; Malinauskas, Tomas; Ruza, Reinis R.; Chang, Tao-Hsin; Yi, Gangshun; Duyvesteyn, Helen M. E.; Yu, Jing; Lu, Weixian; Pardon, Els; Steyaert, Jan; Zhu, Yanan; Ni, Tao; Jones, E. Yvonne

A structure-function analysis shows SARS-CoV-2 BA.2.86 balances antibody escape and ACE2 affinity

CELL REPORTS MEDICINE

IF10.6

2024-05-01

OAAI

Liu, Chang; Zhou, Daming; Dijokaite-Guraliuc, Aiste; Supasa, Piyada; Duyvesteyn, Helen M. E.; Ginn, Helen M.; Selvaraj, Muneeswaran; Mentzer, Alexander J.; Das, Raksha; de Silva, Thushan I.; Ritter, Thomas G.; Plowright, Megan; Newman, Thomas A. H.; Stafford, Lizzie; Kronsteiner, Barbara; Temperton, Nigel; Lui, Yuan; Fellermeyer, Martin; Goulder, Philip; Klenerman, Paul; Dunachie, Susanna J.; Barton, Michael I.; Kutuzov, Mikhail A.; Dushek, Omer; Fry, Elizabeth E.; Mongkolsapaya, Juthathip; Ren, Jingshan; Stuart, David I.; Screaton, Gavin R.

Emerging variants develop total escape from potent monoclonal antibodies induced by BA.4/5 infection

NATURE COMMUNICATIONS

IF15.7

2024-04-16

OAAI

Liu, Chang; Das, Raksha; Dijokaite-Guraliuc, Aiste; Zhou, Daming; Mentzer, Alexander J.; Supasa, Piyada; Selvaraj, Muneeswaran; Duyvesteyn, Helen M. E.; Ritter, Thomas G.; Temperton, Nigel; Klenerman, Paul; Dunachie, Susanna J.; Paterson, Neil G.; Williams, Mark A.; Hall, David R.; Fry, Elizabeth E.; Mongkolsapaya, Juthathip; Ren, Jingshan; Stuart, David I.; Screaton, Gavin R.

The SARS-CoV-2 neutralizing antibody response to SD1 and its evasion by BA.2.86

NATURE COMMUNICATIONS

IF15.7

2024-03-28

OAAI

Zhou, Daming; Supasa, Piyada; Liu, Chang; Dijokaite-Guraliuc, Aiste; Duyvesteyn, Helen M. E.; Selvaraj, Muneeswaran; Mentzer, Alexander J.; Das, Raksha; Dejnirattisai, Wanwisa; Temperton, Nigel; Klenerman, Paul; Dunachie, Susanna J.; Fry, Elizabeth E.; Mongkolsapaya, Juthathip; Ren, Jingshan; Stuart, David I.; Screaton, Gavin R.

Structural and mechanistic characterization of bifunctional heparan sulfate N-deacetylase-N-sulfotransferase 1

NATURE COMMUNICATIONS

IF15.7

2024-02-13

OAAI

Mycroft-West, Courtney J.; Abdelkarim, Sahar; Duyvesteyn, Helen M. E.; Gandhi, Neha S.; Skidmore, Mark A.; Owens, Raymond J.; Wu, Liang

Accelerating drug target inhibitor discovery with a deep generative foundation model

SCIENCE ADVANCES

IF12.5

2023-06-23

OAAI

Chenthamarakshan, Vijil; Hoffman, Samuel C.; Owen, C. David; Lukacik, Petra; Strain-Damerell, Claire; Fearon, Daren; Malla, Tika R.; Tumber, Anthony; Schofield, Christopher J.; Duyvesteyn, Helen M. E.; Dejnirattisai, Wanwisa; Carrique, Loic; Walter, Thomas S.; Screaton, Gavin R.; Matviiuk, Tetiana; Mojsilovic, Aleksandra; Crain, Jason; Walsh, Martin A.; Stuart, David I.; Das, Payel

Rapid escape of new SARS-CoV-2 Omicron variants from BA.2-directed antibody responses

CELL REPORTS

IF6.9

2023-04-01

OAAI

Dijokaite-Guraliuc, Aiste; Das, Raksha; Zhou, Daming; Ginn, Helen M.; Liu, Chang; Duyvesteyn, Helen M. E.; Huo, Jiandong; Nutalai, Rungtiwa; Supasa, Piyada; Selvaraj, Muneeswaran; de Silva, Thushan I.; Plowright, Megan; Newman, Thomas A. H.; Hornsby, Hailey; Mentzer, Alexander J.; Skelly, Donal; Ritter, Thomas G.; Temperton, Nigel; Klenerman, Paul; Barnes, Eleanor; Dunachie, Susanna J.; Roemer, Cornelius; Peacock, Thomas P.; Paterson, Neil G.; Williams, Mark A.; Hall, David R.; Fry, Elizabeth E.; Mongkolsapaya, Juthathip; Ren, Jingshan; Stuart, David I.; Screaton, Gavin R.

A delicate balance between antibody evasion and ACE2 affinity for Omicron BA.2.75

CELL REPORTS

IF6.9

2023-01-01

OAAI

Huo Jiandong; Dijokaite-Guraliuc, Aiste; Liu Chang; Zhou Daming; Ginn, Helen M.; Das, Raksha; Supasa, Piyada; Selvaraj, Muneeswaran; Nutalai, Rungtiwa; Tuekprakhon, Aekkachai; Duyvesteyn, Helen M. E.; Mentzer, Alexander J.; Skelly, Donal; Ritter, Thomas G.; Amini, Ali; Bibi, Sagida; Adele, Sandra; Johnson, Sile Ann; Paterson, Neil G.; Williams, Mark A.; Hall, David R.; Plowright, Megan; Newman, Thomas A. H.; Hornsby, Hailey; de Silva, Thushan, I; Temperton, Nigel; Klenerman, Paul; Barnes, Eleanor; Dunachie, Susanna J.; Pollard, Andrew J.; Lambe, Teresa; Goulder, Philip; Fry, Elizabeth E.; Mongkolsapaya, Juthathip; Ren, Jingshan; Stuart, David I.; Screaton, Gavin R.

Switching of Receptor Binding Poses between Closely Related Enteroviruses

VIRUSES-BASEL

IF3.5

2022-11-24

OAAI

Zhou, Daming; Qin, Ling; Duyvesteyn, Helen M. E.; Zhao, Yuguang; Lin, Tzou-Yien; Fry, Elizabeth E.; Ren, Jingshan; Huang, Kuan-Ying A.; Stuart, David I.

Nonlytic cellular release of hepatitis A virus requires dual capsid recruitment of the ESCRT-associated Bro1 domain proteins HD-PTP and ALIX

PLOS PATHOGENS

IF4.9

2022-08-15

OAAI

Shirasaki, Takayoshi; Feng, Hui; Duyvesteyn, Helen M. E.; Fusco, William G.; McKnight, Kevin L.; Xie, Ling; Boyce, Mark; Kumar, Sathish; Barouch-Bentov, Rina; Gonzalez-Lopez, Olga; McNamara, Ryan; Wang, Li; Hertel-Wulff, Adriana; Chen, Xian; Einav, Shirit; Duncan, Joseph A.; Kapustina, Maryna; Fry, Elizabeth E.; Stuart, David, I; Lemon, Stanley M.

Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2 抗RBD人单克隆抗体的结构和治疗SARS-CoV-2的潜力

THERANOSTICS

IF13.3

2022-01-01

OAAI

Huang, Kuan-Ying A.; Zhou, Daming; Tan, Tiong Kit; Chen, Charles; Duyvesteyn, Helen M. E.; Zhao, Yuguang; Ginn, Helen M.; Qin, Ling; Rijal, Pramila; Schimanski, Lisa; Donat, Robert; Harding, Adam; Gilbert-Jaramillo, Javier; James, William; Tree, Julia A.; Buttigieg, Karen; Carroll, Miles; Charlton, Sue; Lien, Chia-En; Lin, Meei-Yun; Chen, Cheng-Pin; Cheng, Shu-Hsing; Chen, Xiaorui; Lin, Tzou-Yien; Fry, Elizabeth E.; Ren, Jingshan; Ma, Che; Townsend, Alain R.; Stuart, David, I

Neutralization potency of monoclonal antibodies recognizing dominant and subdominant epitopes on SARS-CoV-2 Spike is impacted by the B.1.1.7 variant

IMMUNITY

IF26.3

2021-06-01

OAAI

Graham, Carl; Seow, Jeffrey; Huettner, Isabella; Khan, Hataf; Kouphou, Neophytos; Acors, Sam; Winstone, Helena; Pickering, Suzanne; Galao, Rui Pedro; Dupont, Liane; Lista, Maria Jose; Jimenez-Guardeno, Jose M.; Laing, Adam G.; Wu, Yin; Joseph, Magdalene; Muir, Luke; van Gils, Marit J.; Ng, Weng M.; Duyvesteyn, Helen M. E.; Zhao, Yuguang; Bowden, Thomas A.; Shankar-Hari, Manu; Rosa, Annachiara; Cherepanov, Peter; McCoy, Laura E.; Hayday, Adrian C.; Neil, Stuart J. D.; Malim, Michael H.; Doores, Katie J.

Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2 (vol 27, pg 846, 2020)

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2021-02-03

OAAI

Huo, Jiandong; Le Bas, Audrey; Ruza, Reinis R.; Duyvesteyn, Helen M. E.; Mikolajek, Halina; Malinauskas, Tomas; Tan, Tiong Kit; Rijal, Pramila; Dumoux, Maud; Ward, Philip N.; Ren, Jingshan; Zhou, Daming; Harrison, Peter J.; Weckener, Miriam; Clare, Daniel K.; Vogirala, Vinod K.; Radecke, Julika; Moynie, Lucile; Zhao, Yuguang; Gilbert-Jaramillo, Javier; Knight, Michael L.; Tree, Julia A.; Buttigieg, Karen R.; Coombes, Naomi; Elmore, Michael J.; Carroll, Miles W.; Carrique, Loic; Shah, Pranav N. M.; James, William; Townsend, Alain R.; Stuart, David I.; Owens, Raymond J.; Naismith, James H.

A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses

NATURE COMMUNICATIONS

IF15.7

2021-01-22

222

OAAI

Tan, Tiong Kit; Rijal, Pramila; Rahikainen, Rolle; Keeble, Anthony H.; Schimanski, Lisa; Hussain, Saira; Harvey, Ruth; Hayes, Jack W. P.; Edwards, Jane C.; McLean, Rebecca K.; Martini, Veronica; Pedrera, Miriam; Thakur, Nazia; Conceicao, Carina; Dietrich, Isabelle; Shelton, Holly; Ludi, Anna; Wilsden, Ginette; Browning, Clare; Zagrajek, Adrian K.; Bialy, Dagmara; Bhat, Sushant; Stevenson-Leggett, Phoebe; Hollinghurst, Philippa; Tully, Matthew; Moffat, Katy; Chiu, Chris; Waters, Ryan; Gray, Ashley; Azhar, Mehreen; Mioulet, Valerie; Newman, Joseph; Asfor, Amin S.; Burman, Alison; Crossley, Sylvia; Hammond, John A.; Tchilian, Elma; Charleston, Bryan; Bailey, Dalan; Tuthill, Tobias J.; Graham, Simon P.; Duyvesteyn, Helen M. E.; Malinauskas, Tomas; Huo, Jiandong; Tree, Julia A.; Buttigieg, Karen R.; Owens, Raymond J.; Carroll, Miles W.; Daniels, Rodney S.; McCauley, John W.; Stuart, David I.; Huang, Kuan-Ying A.; Howarth, Mark; Townsend, Alain R.

研究方向