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Rebecca A. Porritt

Sanford Burnham Prebys Medical Discovery Institute
H指数:25
被引数:3,055

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Inhibiting cyclin D1–CDK6 suppresses senescence-associated inflammatory gene expression and age-related functional decline

抑制cyclin D1–CDK6可抑制衰老相关炎症基因表达和年龄相关功能下降

2026-08-200
PRE
Mitochondrial metabolism and epigenetic crosstalk drive SASP

线粒体代谢与表观遗传学串扰驱动SASP

Nature
IF48.5
2026-07-290
OA
p53 enhances DNA repair and suppresses cytoplasmic chromatin fragments and inflammation in senescent cells

p53增强DNA修复,并抑制衰老细胞中的细胞质染色质片段和炎症。

2025-03-050
OA
Apoptotic stress causes mtDNA release during senescence and drives the SASP

凋亡应激导致衰老过程中mtDNA释放并驱动SASP

Nature
IF48.5
2023-10-110
OAAI
Spatial mapping of cellular senescence: emerging challenges and opportunities

细胞衰老的空间图谱: 新出现的挑战和机遇

2023-07-0344
OA
Osteopontin depletion in macrophages perturbs proteostasis via regulating UCHL1-UPS axis and mitochondria-mediated apoptosis

巨噬细胞中骨桥蛋白的耗竭通过调节UCHL1-UPS轴和线粒体介导的细胞凋亡来干扰蛋白平衡

2023-05-306
OAAI
Autophagy-mitophagy induction attenuates cardiovascular inflammation in a murine model of Kawasaki disease vasculitis
2021-09-2240
OAAI
Multisystem inflammatory syndrome in children is driven by zonulin-dependent loss of gut mucosal barrier
2021-07-15178
OA