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The role of ATP synthase subunit e (ATP5I) in mediating the metabolic and antiproliferative effects of metformin in cancer cells ATP合酶亚基e（ATP5I）在介导二甲双胍对癌细胞代谢和抗增殖效应中的作用 Lefrancois, Guillaume; Lavallee, Emilie; Rowell, Marie-Camille; Bourdeau, Veronique; Mohebali, Farzaneh; Bertomeu, Thierry; Duman, Ana Maria; Nikolova, Maya; Tyers, Mike; Gravel, Simon-Pierre; Schmitzer, Andreea R.; Ferbeyre, Gerardo 分享 收藏
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Swi4-dependent SWI4 transcription couples cell size to cell cycle commitment Swi4依赖性SWI4转录将细胞大小与细胞周期决定耦合 Goswami, Pooja; Ghimire, Abhishek; Coffin, Carleton; Cheng, Jing; Coulombe-Huntington, Jasmin; Ghazal, Ghada; Thattikota, Yogitha; Guerra, Maria Florencia; Tyers, Mike; Tolllis, Sylvain; Royer, Catherine A. 分享 收藏
Active growth signaling promotes senescence and cancer cell sensitivity to CDK7 inhibition Wilson, Gemma A.; Vuina, Karla; Sava, Georgina; Huard, Caroline; Meneguello, Leticia; Coulombe-Huntington, Jasmin; Bertomeu, Thierry; Maizels, Rory J.; Lauring, Josh; Kriston-Vizi, Janos; Tyers, Mike; Ali, Simak; Bertoli, Cosetta; de Bruin, Robertus A. M. 分享 收藏
RECOVER identifies synergistic drug combinations in vitro through sequential model optimization Bertin, Paul; Rector-Brooks, Jarrid; Sharma, Deepak; Gaudelet, Thomas; Anighoro, Andrew; Gross, Torsten; Martinez-Pena, Francisco; Tang, Eileen L.; Suraj, M. S.; Regep, Cristian; Hayter, Jeremy B. R.; Korablyov, Maksym; Valiante, Nicholas; van der Sloot, Almer; Tyers, Mike; Roberts, Charles E. S.; Bronstein, Michael M.; Lairson, Luke L.; Taylor-King, Jake P.; Bengio, Yoshua 分享 收藏
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CIF-1, a shared subunit of the COP9/signalosome and eukaryotic initiation factor 3 complexes, regulates MEL-26 levels in the Caenorhabditis elegans embryo Luke-Glaser, Sarah; Roy, Marcia; Larsen, Brett; Le Bihan, Thierry; Metalnikov, Pavel; Tyers, Mike; Peter, Matthias; Pintard, Lionel 分享 收藏
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Panspecies Small-Molecule Disruptors of Heterochromatin-Mediated Transcriptional Gene Silencing 异染色质介导的转录基因沉默的泛种小分子干扰物 Castonguay, Emilie; White, Sharon A.; Kagansky, Alexander; St-Cyr, Daniel J.; Castillo, Araceli G.; Brugger, Christiane; White, Rachel; Bonilla, Carolina; Spitzer, Michaela; Earnshaw, William C.; Schalch, Thomas; Ekwall, Karl; Tyers, Mike; Allshire, Robin C. 分享 收藏
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UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex Chagraoui, Jalila; Girard, Simon; Spinella, Jean-Francois; Simon, Laura; Bonneil, Eric; Mayotte, Nadine; MacRae, Tara; Coulombe-Huntington, Jasmin; Bertomeu, Thierry; Moison, Celine; Tomellini, Elisa; Thibault, Pierre; Tyers, Mike; Marinier, Anne; Sauvageau, Guy 分享 收藏
ALDH2 Mediates 5-Nitrofuran Activity in Multiple Species (vol 19, pg 883, 2012) Zhou, Linna; Ishizaki, Hironori; Spitzer, Michaela; Taylor, Kerrie L.; Temperley, Nicholas D.; Johnson, Stephen L.; Brear, Paul; Gautier, Philippe; Zeng, Zhiqiang; Mitchell, Amy; Narayan, Vikram; McNeil, Ewan M.; Melton, David W.; Smith, Terry K.; Tyers, Mike; Westwood, Nicholas J.; Patton, E. Elizabeth 分享 收藏
Genome-Wide Screens Reveal that Resveratrol Induces Replicative Stress in Human Cells Benslimane, Yahya; Bertomeu, Thierry; Coulombe-Huntington, Jasmin; McQuaid, Mary; Sanchez-Osuna, Maria; Papadopoli, David; Avizonis, Daina; Russo, Mariana De Sa Tavares; Huard, Caroline; Topisirovic, Ivan; Wurtele, Hugo; Tyers, Mike; Harrington, Lea 分享 收藏
Caenorhabditis elegans is a useful model for anthelmintic discovery (Jun, 10.1038/ncomms8485, 2015) Burns, Andrew R.; Luciani, Genna M.; Musso, Gabriel; Bagg, Rachel; Yeo, May; Zhang, Yuqian; Rajendran, Luckshi; Glavin, John; Hunter, Robert; Redman, Elizabeth; Stasiuk, Susan; Schertzberg, Michael; McQuibban, G. Angus; Caffrey, Conor R.; Cutler, Sean R.; Tyers, Mike; Giaever, Guri; Nislow, Corey; Fraser, Andy G.; MacRae, Calum A.; Gilleard, John; Roy, Peter J. 分享 收藏
Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development Jacques, Samuel; van der Sloot, Almer M.; Huard, Caroline; Coulombe-Huntington, Jasmin; Tsao, Sarah; Tollis, Sylvain; Bertomeu, Thierry; Culp, Elizabeth J.; Pallant, Daniel; Cook, Michael A.; Bonneil, Eric; Thibault, Pierre; Wright, Gerard D.; Tyers, Mike 分享 收藏
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The BioC-BioGRID corpus: full text articles annotated for curation of protein-protein and genetic interactions Dogan, Rezarta Islamaj; Kim, Sun; Chatr-aryamontri, Andrew; Chang, Christie S.; Oughtred, Rose; Rust, Jennifer; Wilbur, W. John; Comeau, Donald C.; Dolinski, Kara; Tyers, Mike 分享 收藏
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