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Mito-metformin protects against mitochondrial dysfunction and dopaminergic neuronal degeneration by activating upstream PKD1 signaling in cell culture and MitoPark animal models of Parkinson's disease Ay, Muhammet; Charli, Adhithiya; Langley, Monica; Jang, Ahyoung; Padhi, Piyush; Jin, Huajun; Anantharam, Vellareddy; Kalyanaraman, Balaraman; Kanthasamy, Arthi; Kanthasamy, Anumantha G. 分享 收藏
Environmental neurotoxic pesticide exposure induces gut inflammation and enteric neuronal degeneration by impairing enteric glial mitochondrial function in pesticide models of Parkinson's disease: Potential relevance to gut-brain axis inflammation in Parkinson's disease pathogenesis Palanisamy, Bharathi N.; Sarkar, Souvarish; Malovic, Emir; Samidurai, Manikandan; Charli, Adhithiya; Zenitsky, Gary; Jin, Huajun; Anantharam, Vellareddy; Kanthasamy, Arthi; Kanthasamy, Anumantha G. 分享 收藏
Clostridioides difficile Infection Dysregulates Brain Dopamine Metabolism Vinithakumari, Akhil A.; Padhi, Piyush; Hernandez, Belen; Lin, Susanne Je-Han; Dunkerson-Kurzhumov, Aaron; Showman, Lucas; Breitzman, Matthew; Stokes, Caroline; Sulaiman, Yousuf; Tangudu, Chandra; Kuttappan, Deepa A.; Muyyarikkandy, Muhammed S.; Willette, Auriel A.; Phillips, Gregory J.; Anantharam, Vellareddy; Perera, Ann; Sponseller, Brett A.; Kanthasamy, Anumantha; Mooyottu, Shankumar 分享 收藏
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Mitochondrial dysfunction-induced H3K27 hyperacetylation perturbs enhancers in Parkinson's disease 帕金森氏病中线粒体功能障碍诱导的H3K27高乙酰化干扰增强剂 Huang, Minhong; Lou, Dan; Charli, Adhithiya; Kong, Dehui; Jin, Huajun; Zenitsky, Gary; Anantharam, Vellareddy; Kanthasamy, Arthi; Wang, Zhibin; Kanthasamy, Anumantha G. 分享 收藏
Chronic Manganese Exposure and the Enteric Nervous System: An in Vitro and Mouse in Vivo Study Ghaisas, Shivani; Harichandra, Dilshan S.; Palaniswamy, Bharathi; Proctor, Alexandra; Jin, Huajun; Dutta, Somak; Sarkar, Souvarish; Langley, Monica; Zenitsky, Gary; Anantharam, Vellareddy; Kanthasamy, Arthi; Phillips, Gregory J.; Kanthasamy, Anumantha 分享 收藏
PKC Delta Activation Promotes Endoplasmic Reticulum Stress (ERS) and NLR Family Pyrin Domain-Containing 3 (NLRP3) Inflammasome Activation Subsequent to Asynuclein-Induced Microglial Activation: Involvement of Thioredoxin-Interacting Protein (TXNIP)/Thioredoxin (Trx) Redoxisome Pathway Samidurai, Manikandan; Palanisamy, Bharathi N.; Bargues-Carot, Alejandra; Hepker, Monica; Kondru, Naveen; Manne, Sireesha; Zenitsky, Gary; Jin, Huajun; Anantharam, Vellareddy; Kanthasamy, Anumantha G.; Kanthasamy, Arthi 分享 收藏
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Tumor Necrosis Factor-Like Weak Inducer of Apoptosis (TWEAK) Enhances Activation of STAT3/NLRC4 Inflammasome Signaling Axis through PKCδ in Astrocytes: Implications for Parkinson's Disease Samidurai, Manikandan; Tarale, Prashant; Janarthanam, Chelva; Estrada, Crystal Gomez; Gordon, Richard; Zenitsky, Gary; Jin, Huajun; Anantharam, Vellareddy; Kanthasamy, Anumantha G.; Kanthasamy, Arthi 分享 收藏
Kv1.3 modulates neuroinflammation and neurodegeneration in Parkinson's disease Sarkar, Souvarish; Nguyen, Hai M.; Malovic, Emir; Luo, Jie; Langley, Monica; Palanisamy, Bharathi N.; Singh, Neeraj; Manne, Sireesha; Neal, Matthew; Gabrielle, Michelle; Abdalla, Ahmed; Anantharam, Poojya; Rokad, Dharmin; Panicker, Nikhil; Singh, Vikrant; Ay, Muhammet; Charli, Adhithiya; Harischandra, Dilshan; Jin, Lee-Way; Jin, Huajun; Rangaraju, Srikant; Anantharam, Vellareddy; Wulff, Heike; Kanthasamy, Anumantha G. 分享 收藏
An Ex Vivo Brain Slice Culture Model of Chronic Wasting Disease: Implications for Disease Pathogenesis and Therapeutic Development Kondru, Naveen; Manne, Sireesha; Kokemuller, Robyn; Greenlee, Justin; Greenlee, M. Heather West; Nichols, Tracy; Kong, Qingzhong; Anantharam, Vellareddy; Kanthasamy, Arthi; Halbur, Patrick; Kanthasamy, Anumantha G. 分享 收藏
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Identification of chronic brain protein changes and protein targets of serum auto-antibodies after blast-mediated traumatic brain injury 爆炸介导的创伤性脑损伤后慢性脑蛋白变化及血清自身抗体蛋白靶点的鉴定 Harper, Matthew M.; Rudd, Danielle; Meyer, Kacie J.; Kanthasamy, Anumantha G.; Anantharam, Vellareddy; Pieper, Andrew A.; Vazquez-Rosa, Edwin; Shin, Min-Kyoo; Chaubey, Kalyani; Koh, Yeojung; Evans, Lucy P.; Bassuk, Alexander G.; Anderson, Michael G.; Dutca, Laura; Kudva, Indira T.; John, Manohar 分享 收藏
Inducible nitric oxide synthase inhibitor, 1400W, mitigates DFP-induced long-term neurotoxicity in the rat model Putra, Marson; Sharma, Shaunik; Gage, Meghan; Gasser, Grace; Hinojo-Perez, Andy; Olson, Ashley; Gregory-Flores, Adriana; Puttachary, Sreekanth; Wang, Chong; Anantharam, Vellareddy; Thippeswamy, Thimmasettappa 分享 收藏
MitoPark transgenic mouse model recapitulates the gastrointestinal dysfunction and gut-microbiome changes of Parkinson's disease MitoPark转基因小鼠模型概括了帕金森病的胃肠功能障碍和肠道菌群变化 Ghaisas, Shivani; Langley, Monica R.; Palanisamy, Bharathi N.; Dutta, Somak; Narayanaswamy, Kirthi; Plummer, Paul J.; Sarkar, Souvarish; Ay, Muhammet; Jin, Huajun; Anantharam, Vellareddy; Kanthasamy, Arthi; Kanthasamy, Anumantha G. 分享 收藏
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