Robert A. Roth - Publications, H-index & Citations

Robert A. Roth

michigan state university

58H指数

426论文数

1.1W被引数

收录论文 72

发表时间

Pharmacokinetic and toxicodynamic concepts in idiosyncratic, drug-induced liver injury 特异质性药物性肝损伤中的药代动力学与毒效动力学概念

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY

IF3.4

2022-08-24

OAAI

Roth, Robert A.; Kana, Omar; Filipovic, David; Ganey, Patricia E.

Key Characteristics of Human Hepatotoxicants as a Basis for Identification and Characterization of the Causes of Liver Toxicity

HEPATOLOGY

IF15.8

2021-12-01

OAAI

Rusyn, Ivan; Arzuaga, Xabier; Cattley, Russell C.; Corton, J. Christopher; Ferguson, Stephen S.; Godoy, Patricio; Guyton, Kathryn Z.; Kaplowitz, Neil; Khetani, Salman R.; Roberts, Ruth A.; Roth, Robert A.; Smith, Martyn T.

Von Willebrand factor delays liver repair after acetaminophen-induced acute liver injury in mice

JOURNAL OF HEPATOLOGY

IF33

2020-01-01

OAAI

Groeneveld, Dafna; Cline-Fedewa, Holly; Baker, Kevin S.; Williams, Kurt J.; Roth, Robert A.; Mittermeier, Karen; Lisman, Ton; Palumbo, Joseph S.; Luyendyk, James P.

Representing the Process of Inflammation as Key Events in Adverse Outcome Pathways 将炎症过程表示为不良结果途径中的关键事件

TOXICOLOGICAL SCIENCES

IF4.1

2018-02-22

OAAI

Villeneuve, Daniel L.; Landesmann, Brigitte; Allavena, Paola; Ashley, Noah; Bal-Price, Anna; Corsini, Emanuela; Halappanavar, Sabina; Hussell, Tracy; Laskin, Debra; Lawrence, Toby; Nikolic-Paterson, David; Pallardy, Marc; Paini, Alicia; Pieters, Raymond; Roth, Robert; Tschudi-Monnet, Florianne

Synergistic Cytotoxicity from Drugs and Cytokines In Vitro as an Approach to Classify Drugs According to Their Potential to Cause Idiosyncratic Hepatotoxicity: A Proof-of-Concept Study

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2017-09-01

OAAI

Maiuri, Ashley R.; Wassink, Bronlyn; Turkus, Jonathan D.; Breier, Anna B.; Lansdell, Theresa; Kaur, Gurpreet; Hession, Sarah L.; Ganey, Patricia E.; Roth, Robert A.

Calcium Contributes to the Cytotoxic Interaction Between Diclofenac and Cytokines

TOXICOLOGICAL SCIENCES

IF4.1

2015-11-24

OAAI

Maiuri, Ashley R.; Breier, Anna B.; Turkus, Jonathan D.; Ganey, Patricia E.; Roth, Robert A.

A Cytochrome P450-Independent Mechanism of Acetaminophen-Induced Injury in Cultured Mouse Hepatocytes

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2015-08-01

OAAI

Miyakawa, Kazuhisa; Albee, Ryan; Letzig, Lynda G.; Lehner, Andreas F.; Scott, Michael A.; Buchweitz, John P.; James, Laura P.; Ganey, Patricia E.; Roth, Robert A.

Trovafloxacin-induced replication stress sensitizes HepG2 cells to tumor necrosis factor-alpha-induced cytotoxicity mediated by extracellular signal-regulated kinase and ataxia telangiectasia and Rad3-related

TOXICOLOGY

IF4.6

2015-05-01

OAAI

Beggs, Kevin M.; Maiuri, Ashley R.; Fullerton, Aaron M.; Poulsen, Kyle L.; Breier, Anna B.; Ganey, Patricia E.; Roth, Robert A.

Trovafloxacin Enhances Lipopolysaccharide-Stimulated Production of Tumor Necrosis Factor-α by Macrophages: Role of the DNA Damage Response

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2014-07-01

OAAI

Poulsen, Kyle L.; Olivero-Verbel, Jesus; Beggs, Kevin M.; Ganey, Patricia E.; Roth, Robert A.

Trovafloxacin Potentiation of Lipopolysaccharide-Induced Tumor Necrosis Factor Release from RAW 264.7 Cells Requires Extracellular Signal-Regulated Kinase and c-Jun N-Terminal Kinase

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2014-05-01

OAAI

Poulsen, Kyle L.; Albee, Ryan P.; Ganey, Patricia E.; Roth, Robert A.

Molecular Mechanisms of Hepatocellular Apoptosis Induced by Trovafloxacin-Tumor Necrosis Factor-alpha Interaction

TOXICOLOGICAL SCIENCES

IF4.1

2013-10-04

OAAI

Beggs, Kevin M.; Fullerton, Aaron M.; Miyakawa, Kazuhisa; Ganey, Patricia E.; Roth, Robert A.

Pretreatment With TCDD Exacerbates Liver Injury From Concanavalin A: Critical Role for NK Cells

TOXICOLOGICAL SCIENCES

IF4.1

2013-08-22

OAAI

Fullerton, Aaron M.; Roth, Robert A.; Ganey, Patricia E.

Roles of the Hemostatic System and Neutrophils in Liver Injury From Co-exposure to Amiodarone and Lipopolysaccharide 止血系统和中性粒细胞在胺碘酮和脂多糖联合染毒肝损伤中的作用

TOXICOLOGICAL SCIENCES

IF4.1

2013-08-02

OAAI

Lu, Jingtao; Roth, Robert A.; Malle, Ernst; Ganey, Patricia E.

2,3,7,8-TCDD enhances the sensitivity of mice to concanavalin A immune-mediated liver injury

TOXICOLOGY AND APPLIED PHARMACOLOGY

IF3.4

2013-01-01

OAAI

Fullerton, Aaron M.; Roth, Robert A.; Ganey, Patricia E.

Comparative NMR-Based Metabonomic Investigation of the Metabolic Phenotype Associated with Tienilic Acid and Tienilic Acid Isomer

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2012-11-05

PREAI

Coen, Muireann; Rademacher, Peter M.; Zou, Wei; Scott, Michael; Ganey, Patricia E.; Roth, Robert; Nelson, Sidney D.

Tumor Necrosis Factor-alpha Potentiates the Cytotoxicity of Amiodarone in Hepa1c1c7 Cells: Roles of Caspase Activation and Oxidative Stress

TOXICOLOGICAL SCIENCES

IF4.1

2012-10-05

OAAI

Lu, Jingtao; Miyakawa, Kazuhisa; Roth, Robert A.; Ganey, Patricia E.

Hypoxia sensitization of hepatocytes to neutrophil elastase-mediated cell death depends on MAPKs and HIF-1α

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

IF3.3

2012-04-01

OAAI

Sparkenbaugh, Erica M.; Ganey, Patricia E.; Roth, Robert A.

Neutrophil-cytokine interactions in a rat model of sulindac-induced idiosyncratic liver injury 舒林酸诱导的特异质肝损伤大鼠模型中的中性粒细胞-细胞因子相互作用

TOXICOLOGY

IF4.6

2011-12-01

OAAI

Zou, Wei; Roth, Robert A.; Younis, Husam S.; Malle, Ernst; Ganey, Patricia E.

Amiodarone Exposure During Modest Inflammation Induces Idiosyncrasy-like Liver Injury in Rats: Role of Tumor Necrosis Factor-alpha

TOXICOLOGICAL SCIENCES

IF4.1

2011-10-09

OAAI

Lu, Jingtao; Jones, A. Daniel; Harkema, Jack R.; Roth, Robert A.; Ganey, Patricia E.

The Role of Hypoxia-Inducible Factor-1α in Acetaminophen Hepatotoxicity

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2011-08-01

OAAI

Sparkenbaugh, Erica M.; Saini, Yogesh; Greenwood, Krista K.; LaPres, John J.; Luyendyk, James P.; Copple, Bryan L.; Maddox, Jane F.; Ganey, Patricia E.; Roth, Robert A.

研究方向