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I

Ivan Ahel

university of oxford

65H指数
352论文数
1.3W被引数
收录论文 66
发表时间
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Filament formation and NAD processing by noncanonical human FAM118 sirtuins非经典人FAM118去乙酰化酶的丝状体形成与NAD处理
errNature Structural & Molecular Biology
IF10.1
err2025-11-17
err0
errOAAI
errDomagoj Baretić; Sophia Missoury; Karishma Patel; Maximilien Martinez; Franck Coste; Kang Zhu; Rebecca Smith; Anna Georgina Kopasz; Yang Lu; Nicolas Bigot; Catherine Chapuis; Romane Riou; Nina Đukić; Stéphane Goffinont; Valentin Pressoir; Sara Patačko; Gyula Timinszky; Marc Delarue; Bertrand Castaing; Dragana Ahel; Andreja Mikoč; Sébastien Huet; Ivan Ahel; Marcin J. Suskiewicz
err分享
err收藏
A FRET-Based High-Throughput Screening Assay for the Discovery of Mycobacterium tuberculosis DNA ADP-Ribosylglycohydrolase DarG Inhibitors一种基于FRET的高通量筛选方法，用于发现结核分枝杆菌Mycobacterium tuberculosis DNA腺苷二磷酸核糖基糖苷酶DarG抑制剂
errACS Infectious Diseases
IF3.8
err2025-10-30
err0
PREAI
errMen Thi Hoai Duong; Yang Lu; Ivan Ahel; Lari Lehtiö
err分享
err收藏
Interplay between ubiquitination and ADP-ribosylation and the case of dual modification ADPr-Ub泛素化与ADP-核糖基化之间的相互作用及双重修饰ADPr-Ub的情况
errESSAYS IN BIOCHEMISTRY
IF5.7
err2025-10-01
err0
errOAAI
errZhu, Kang; Chatrin, Chatrin; Smith, Rebecca; Ahel, Dragana; Ahel, Ivan
err分享
err收藏
Regulation of a phage defence island by RptR, a novel repressor that controls restriction-modification systems in diverse bacteria由RptR调控的一个噬菌体防御岛，RptR是一种新型抑制因子，可控制多种细菌中的限制-修饰系统
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-07-22
err2
errOAAI
errZhang, YuGeng; Schuller, Marion; Ahel, Ivan; Blower, Tim R.; Exley, Rachel M.; Tang, Christoph M.
err分享
err收藏
Identification of RNF114 as ADPr-Ub reader through non-hydrolysable ubiquitinated ADP-ribose通过非水解泛素化ADP-核糖鉴定RNF114为ADPr-Ub的阅读器
errNature Communications
IF15.7
err2025-07-09
err0
errOAAI
errMax S. Kloet; Chatrin Chatrin; Rishov Mukhopadhyay; Bianca D. M. van Tol; Rebecca Smith; Sarah A. Rotman; Rayman T. N. Tjokrodirijo; Kang Zhu; Andrii Gorelik; Lucy Maginn; Paul R. Elliott; Peter A. van Veelen; Dragana Ahel; Ivan Ahel; Gerbrand J. van der Heden van Noort
err分享
err收藏
PARPs and ADP-ribosyl hydrolases in cancer therapy: From drug targets to biomarkersPARP和ADP核糖基水解酶在癌症治疗中的应用：从药物靶点到生物标志物
errDNA Repair
IF2.7
err2025-06-24
err0
errOAAI
errJoséphine Groslambert; Kira Schützenhofer; Luca Palazzo; Ivan Ahel
err分享
err收藏
Control of replication and gene expression by ADP-ribosylation of DNA in Mycobacterium tuberculosis分枝杆菌中DNA的ADP-核糖基化对复制和基因表达的调控
errEMBO JOURNAL
IF8.3
err2025-05-08
err0
errOAAI
errButler, Rachel E.; Schuller, Marion; Jaiswal, Ritu; Mukhopadhyay, Jayanta; Barber, Jim; Hingley-Wilson, Suzie; Wasson, Emily; Alves, Alex Couto; Ahel, Ivan; Stewart, Graham R.
err分享
err收藏
Discovery of reversing enzymes for RNA ADP-ribosylation reveals a possible defence module against toxic attack发现逆转RNA ADP-核糖基化反应的酶揭示了对抗毒性攻击的一种可能防御模块
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-02-18
err0
errOAAI
errLu, Yang; Schuller, Marion; Bullen, Nathan P.; Mikolcevic, Petra; Zonjic, Iva; Raggiaschi, Roberto; Mikoc, Andreja; Whitney, John C.; Ahel, Ivan
err分享
err收藏
Suppression of ADP-ribosylation reversal triggers cell vulnerability to alkylating agents
errNEOPLASIA
IF7.7
err2025-01-01
err0
PREAI
errCaggiano, Rocco; Prokhorova, Evgeniia; Duma, Lena; Schutzenhofer, Kira; Lauro, Raffaella; Catara, Giuliana; Melillo, Rosa Marina; Celetti, Angela; Smith, Rebecca; Weroha, S. John; Kaufmann, Scott H.; Ahel, Ivan; Palazzo, Luca
err分享
err收藏
Reversal of tyrosine-linked ADP-ribosylation by ARH3 and PARG
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-11-01
err1
errOAAI
errRack, Johannes Gregor Matthias; Voorneveld, Jim; Longarini, Edoardo Jose; Wijngaarden, Sven; Zhu, Kang; Peters, Alessandra; Sia, Jia Jhing; Prokhorova, Evgeniia; Ahel, Dragana; Matic, Ivan; V. Filippov, Dmitri; Ahel, Ivan
err分享
err收藏
Evolutionary and molecular basis of ADP-ribosylation reversal by zinc-dependent macrodomains
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-10-01
err0
errOAAI
errAriza, Antonio; Liu, Qiang; Cowieson, Nathan P.; Ahel, Ivan; Filippov, Dmitri V.; Rack, Johannes Gregor Matthias
err分享
err收藏
PARP14 and PARP9/DTX3L regulate interferon-induced ADP-ribosylation (vol 43, pg 2929,2024)
errEMBO JOURNAL
IF8.3
err2024-09-25
err0
errOAAI
errKar, Pulak; Chatrin, Chatrin; Dukic, Nina; Suyari, Osamu; Schuller, Marion; Zhu, Kang; Prokhorova, Evgeniia; Bigot, Nicolas; Baretic, Domagoj; Ahel, Juraj; Elsborg, Jonas Damgaard; Nielsen, Michael L.; Clausen, Tim; Huet, Sebastien; Niepel, Mario; Sanyal, Sumana; Ahel, Dragana; Smith, Rebecca; Ahel, Ivan
err分享
err收藏
Ubiquitylation of nucleic acids by DELTEX ubiquitin E3 ligase DTX3LDELTEX泛素E3连接酶DTX3L对核酸的泛素化
errEMBO REPORTS
IF6.2
err2024-09-06
err2
errOAAI
errZhu, Kang; Chatrin, Chatrin; Suskiewicz, Marcin J.; Aucagne, Vincent; Foster, Benjamin; Kessler, Benedikt M.; Gibbs-Seymour, Ian; Ahel, Dragana; Ahel, Ivan
err分享
err收藏
Synthesis of Structural ADP-Ribose Analogues as Inhibitors for SARS-CoV-2 Macrodomain 1
errORGANIC LETTERS
IF5
err2024-06-27
err0
errOAAI
errRijpkema, Koen J.; Schuller, Marion; van der Veer, Miriam S.; Rieken, Sjoerd; Chang, Diego L. R.; Balic, Pascal; Todorov, Alex; Minnee, Hugo; Wijngaarden, Sven; Matos, Isaac A.; Hoch, Nicolas C.; Codee, Jeroen D. C.; Ahel, Ivan; Filippov, Dmitri V.
err分享
err收藏
Histone ADPribosylation promotes resistance to PARP inhibitors by facilitating PARP1 release from DNA lesions
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-06-12
err1
PREAI
errZentout, Siham; Imburchia, Victor; Chapuis, Catherine; Duma, Lena; Schuetzenhofer, Kira; Prokhorova, Evgeniia; Ahel, Ivan; Smith, Rebecca; Huet, Sebastien
err分享
err收藏
PARP14 and PARP9/DTX3L regulate interferon-induced ADP-ribosylation
errEMBO JOURNAL
IF8.3
err2024-06-04
err5
errOAAI
errKar, Pulak; Chatrin, Chatrin; Dukic, Nina; Suyari, Osamu; Schuller, Marion; Zhu, Kang; Prokhorova, Evgeniia; Bigot, Nicolas; Ahel, Juraj; Elsborg, Jonas Damgaard; Nielsen, Michael L.; Clausen, Tim; Huet, Sebastien; Niepel, Mario; Sanyal, Sumana; Ahel, Dragana; Smith, Rebecca; Ahel, Ivan
err分享
err收藏
Deregulated DNA ADP-ribosylation impairs telomere replication
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2024-05-07
err2
errOAAI
errWondisford, Anne R.; Lee, Junyeop; Lu, Robert; Schuller, Marion; Groslambert, Josephine; Bhargava, Ragini; Schamus-Haynes, Sandra; Cespedes, Leyneir C.; Opresko, Patricia L.; Pickett, Hilda A.; Min, Jaewon; Ahel, Ivan; O'Sullivan, Roderick J.
err分享
err收藏
Specificity of DNA ADP-Ribosylation Reversal by NADARs
errTOXINS
IF4
err2024-04-28
err2
errOAAI
errCihlova, Bara; Lu, Yang; Mikoc, Andreja; Schuller, Marion; Ahel, Ivan
err分享
err收藏
Unexpected Noncovalent Off-Target Activity of Clinical BTK Inhibitors Leads to Discovery of a Dual NUDT5/14 Antagonist
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-04-18
err3
errOAAI
errBalikci, Esra; Marques, Anne-Sophie M. C.; Bauer, Ludwig G.; Seupel, Raina; Bennett, James; Raux, Brigitt; Buchan, Karly; Simelis, Klemensas; Singh, Usha; Rogers, Catherine; Ward, Jennifer; Cheng, Carol; Szommer, Tamas; Schutzenhofer, Kira; Elkins, Jonathan M.; Sloman, David L.; Ahel, Ivan; Fedorov, Oleg; Brennan, Paul E.; Huber, Kilian V. M.
err分享
err收藏
Legionella metaeffector MavL reverses ubiquitin ADP-ribosylation via a conserved arginine-specific macrodomain
errNATURE COMMUNICATIONS
IF15.7
err2024-03-19
err4
errOAAI
errZhang, Zhengrui; Fu, Jiaqi; Rack, Johannes Gregor Matthias; Li, Chuang; Voorneveld, Jim; Filippov, Dmitri V.; Ahel, Ivan; Luo, Zhao-Qing; Das, Chittaranjan
err分享
err收藏

研究方向

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合作学者
合作期刊
V
Valina L. Dawson
H 指数: 151 · 论文数: 582
C
Chris P. Ponting
H 指数: 135 · 论文数: 518
A
Alan Ashworth
H 指数: 121 · 论文数: 1.0K
B
Brian K. Shoichet
H 指数: 114 · 论文数: 416
S
Stefan Knapp
H 指数: 111 · 论文数: 1.3K
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