未登录 Mediator kinase inhibition reverses castration resistance of advanced cancer Li, Jing; Hilimire, Thomas A.; Liu, Yueying; Wang, Lili; Liang, Jiaxin; Gyorffy, Balazs; Sikirzhytski, Vitali; Ji, Hao; Zhang, Li; Cheng, Chen; Ding, Xiaokai; Kerr, Kendall R.; Dowling, Charles E.; Chumanevich, Alexander A.; Mack, Zachary T.; Schools, Gary P.; Lim, Chang-uk; Ellis, Leigh; Zi, Xiaolin; Porter, Donald C.; Broude, Eugenia V.; McInnes, Campbell; Wilding, George; Lilly, Michael B.; Roninson, Igor B.; Chen, Mengqian 分享 收藏
CDK8/19-regulated transcriptional reprogramming: a druggable driver of castration-resistant prostate cancer Li, Jing; Hilimire, Thomas; Liu, Yueying; Wang, Lili; Liang, Jiaxin; Gyorffy, Balazs; Sikitzhytski, Vitali; Ji, Hao; Zhang, Li; Cheng, Chen; Ding, Xiaokai; Kerr, Kendall; Dowling, Charles; Schools, Gary; Lim, Chang-Uk; Braude, Eugenia; Wilding, George; Lilly, Michael; Roninson, Igor; Chen, Mengqian 分享 收藏
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Predicting Response of Triple-Negative Breast Cancer to Neoadjuvant Chemotherapy Using a Deep Convolutional Neural Network-Based Artificial Intelligence Tool Krishnamurthy, Savitri; Jain, Parag; Tripathy, Debu; Basset, Roland; Randhawa, Ramandeep; Muhammad, Hassan; Huang, Wei; Yang, Hua; Kummar, Shivaani; Wilding, George; Roy, Rajat 分享 收藏
Predicting response of triple negative breast cancer to neoadjuvant chemotherapy using a deep convolutional neural network-based artificial intelligence tool Krishnamurthy, Savitri; Jain, Parag; Tripathy, Debu; Muhammad, Hassan; Huang, Wei; Yang, Hua; Kummar, Shivaani; Wilding, George; Roy, Rajat; Randhawa, Ramandeep 分享 收藏
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Small-molecule inhibitors targeting a specific metabolic pathway for precision therapy of advanced castrate-resistant prostate cancer. Basu, Hirak; Wilganowski, Nathaniel; Lieblich, Jessica; Wu, Grace; Fokt, Izabela; Ramachandran, Sumankalai; Yu, Jiaquin; Titus, Mark; Priebe, Waldemar; Beebe, David J.; Wilding, George 分享 收藏
A metabolic pathway targeted inhibitor for precision therapy of castrate-resistant prostate cancer Basui, Hirak S.; Wilgonowskii, Nathaniel L.; Lieblichi, Jessica L.; Wui, Grace T.; Fokti, Izabela; Ramachandrani, Sumankalai; Yu, Jiaquin; Titusi, Mark; Priebei, Waldemar; Beebe, David J.; Wildingi, George 分享 收藏
Naming disease states for clinical utility in prostate cancer: a rose by any other name might not smell as sweet Armstrong, A. J.; Antonarakis, E. S.; Taplin, M. -E.; Kelly, W. K.; Beltran, H.; Fizazi, K.; Dahut, W. L.; Shore, N.; Slovin, S.; George, D.; Carducci, M. A.; Corn, P.; Danila, D.; Dreicer, R.; Heath, E.; Rathkopf, D.; Liu, G.; Nanus, D.; Stein, M.; Smith, M. R.; Sternberg, C.; Wilding, G.; Nelson, P. S.; Halabi, S.; Kantoff, P.; Clarke, N. W.; Evans, C. P.; Heidenreich, A.; Mottet, N.; Gleave, M.; Morris, M. J.; Scher, H. I. 分享 收藏
Clinical Trial Characteristics and Barriers to Participant Accrual: The MD Anderson Cancer Center Experience over 30 years, a Historical Foundation for Trial Improvement 临床试验的特点和参与者累积的障碍: MD安德森癌症中心30年的经验，试验改进的历史基础 Tang, Chad; Sherman, Steven I.; Price, Mellanie; Weng, Jun; Davis, Suzanne E.; Hong, David S.; Yao, James C.; Buzdar, Aman; Wilding, George; Lee, J. Jack 分享 收藏
Safety of long-term (LT) treatment (tmt) of chemotherapy (chemo)-naive metastatic castration-resistant prostate cancer (mCRPC) patients (pts) with abiraterone acetate plus prednisone (AA plus P) for ≥ 4 years (yrs) Carles, J.; Davis, I.; De Bono, J. S.; Fizazi, K.; Gerritsen, W.; Rathkopf, D. E.; Ryan, C. J.; Saad, F.; Steuber, T.; Wilding, G.; Park, Y. C.; Charnas, R.; De Porre, P.; Van Poppel, H. 分享 收藏
Adjuvant sunitinib or sorafenib for high-risk, non-metastatic renal-cell carcinoma (ECOG-ACRIN E2805): a double-blind, placebo-controlled, randomised, phase 3 trial Haas, Naomi B.; Manola, Judith; Uzzo, Robert G.; Flaherty, Keith T.; Wood, Christopher G.; Kane, Christopher; Jewett, Michael; Dutcher, Janice P.; Atkins, Michael B.; Pins, Michael; Wilding, George; Cella, David; Wagner, Lynne; Matin, Surena; Kuzel, Timothy M.; Sexton, Wade J.; Wong, Yu-Ning; Choueiri, Toni K.; Pili, Roberto; Puzanov, Igor; Kohli, Manish; Stadler, Walter; Carducci, Michael; Coomes, Robert; DiPaola, Robert S. 分享 收藏
Mipsagargin, a novel thapsigargin-based PSMA-activated prodrug: results of a first-in-man phase I clinical trial in patients with refractory, advanced or metastatic solid tumours Mahalingam, D.; Wilding, G.; Denmeade, S.; Sarantopoulas, J.; Cosgrove, D.; Cetnar, J.; Azad, N.; Bruce, J.; Kurman, M.; Allgood, V. E.; Carducci, M. 分享 收藏
A multicenter phase 1/2a dose-escalation study of the antioxidant moiety of vitamin E 2,2,5,7,8-pentamethyl-6-chromanol (APC-100) in men with advanced prostate cancer Kyriakopoulos, Christos E.; Heath, Elisabeth I.; Eickhoff, Jens C.; Kolesar, Jill; Yayehyirad, Mulusew; Moll, Thomas; Wilding, George; Liu, Glenn 分享 收藏
A phase I study of selumetinib (AZD6244/ARRY-142866), a MEK1/2 inhibitor, in combination with cetuximab in refractory solid tumors and KRAS mutant colorectal cancer MEK1/2抑制剂司美替尼 (AZD6244/ARRY-142866) 与西妥昔单抗联合治疗难治性实体瘤和KRAS突变型结直肠癌的I期研究 Deming, Dustin A.; Cavalcante, Ludmila L.; Lubner, Sam J.; Mulkerin, Daniel L.; LoConte, Noelle K.; Eickhoff, Jens C.; Kolesar, Jill M.; Fioravanti, Suzanne; Greten, Tim F.; Compton, Kathryn; Doyle, Austin G.; Wilding, George; Duffy, Austin; Liu, Glenn 分享 收藏
Effect of Renal Impairment on the Pharmacokinetics and Safety of Axitinib Chen, Ying; Rini, Brian I.; Motzer, Robert J.; Dutcher, Janice P.; Rixe, Olivier; Wilding, George; Stadler, Walter M.; Tarazi, Jamal; Garrett, May; Pithavala, Yazdi K. 分享 收藏
Effects of Adjuvant Sorafenib and Sunitinib on Cardiac Function in Renal Cell Carcinoma Patients without Overt Metastases: Results from ASSURE, ECOG 2805 Haas, Naomi B.; Manola, Judith; Ky, Bonnie; Flaherty, Keith T.; Uzzo, Robert G.; Kane, Christopher J.; Jewett, Michael; Wood, Lori; Wood, Christopher G.; Atkins, Michael B.; Dutcher, Janice J.; Wilding, George; DiPaola, Robert S. 分享 收藏
A National Multicenter Phase 2 Study of Prostate-specific Antigen (PSA) Pox Virus Vaccine with Sequential Androgen Ablation Therapy in Patients with PSA Progression: ECOG 9802 DiPaola, Robert S.; Chen, Yu-Hui; Bubley, Glenn J.; Stein, Mark N.; Hahn, Noah M.; Carducci, Michael A.; Lattime, Edmund C.; Gulley, James L.; Arlen, Philip M.; Butterfield, Lisa H.; Wilding, George 分享 收藏
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