未登录 Improving the predictive power of mouse models 提高小鼠模型的预测能力 Pera, Martin; Greene, Andy; Cardon, Lon; Carter, Gregory W.; Chesler, Elissa J.; Churchill, Gary; Kumar, Vivek; Lutz, Cathleen; Munger, Steven; Murray, Steve; O'Connell, Kristen; Reinholdt, Laura; Rosenthal, Nadia A. 分享 收藏
Identifying therapeutic drug targets using bidirectional effect genes Estrada, Karol; Froelich, Steven; Wuster, Arthur; Bauer, Christopher R.; Sterling, Teague; Clark, Wyatt T.; Ru, Yuanbin; Trinidad, Marena; Hong Phuc Nguyen; Luu, Amanda R.; Wendt, Daniel J.; Yogalingam, Gouri; Yu, Guoying Karen; LeBowitz, Jonathan H.; Cardon, Lon R. 分享 收藏
Interleukin-18 as a drug repositioning opportunity for inflammatory bowel disease: A Mendelian randomization study Mokry, Lauren E.; Zhou, Sirui; Guo, Cong; Scott, Robert A.; Devey, Luke; Langenberg, Claudia; Wareham, Nick; Waterworth, Dawn; Cardon, Lon; Sanseau, Philippe; Smith, George Davey; Richards, J. Brent 分享 收藏
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The support of human genetic evidence for approved drug indications 人类遗传证据支持已批准的药物适应症 Nelson, Matthew R.; Tipney, Hannah; Painter, Jeffery L.; Shen, Judong; Nicoletti, Paola; Shen, Yufeng; Floratos, Aris; Sham, Pak Chung; Li, Mulin Jun; Wang, Junwen; Cardon, Lon R.; Whittaker, John C.; Sanseau, Philippe 分享 收藏
Identification of a Variant in KDR Associated with Serum VEGFR2 and Pharmacodynamics of Pazopanib Maitland, Michael L.; Xu, Chun-Fang; Cheng, Yu-Ching; Kistner-Griffin, Emily; Ryan, Kathleen A.; Karrison, Theodore G.; Das, Soma; Torgerson, Dara; Gamazon, Eric R.; Thomeas, Vasiliki; Levine, Matthew R.; Wilson, Paul A.; Bing, Nan; Liu, Yuan; Cardon, Lon R.; Pandite, Lini N.; O'Connell, Jeffrey R.; Cox, Nancy J.; Mitchell, Braxton D.; Ratain, Mark J.; Shuldiner, Alan R. 分享 收藏
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Deep Resequencing Unveils Genetic Architecture of ADIPOQ and Identifies a Novel Low-Frequency Variant Strongly Associated With Adiponectin Variation Warren, Liling L.; Li, Li; Nelson, Matthew R.; Ehm, Margaret G.; Shen, Judong; Fraser, Dana J.; Aponte, Jennifer L.; Nangle, Keith L.; Slater, Andrew J.; Woollard, Peter M.; Hall, Matt D.; Topp, Simon D.; Yuan, Xin; Cardon, Lon R.; Chissoe, Stephanie L.; Mooser, Vincent; Morris, Andrew D.; Palmer, Colin N. A.; Perry, John R.; Frayling, Timothy M.; Whittaker, John C.; Waterworth, Dawn M. 分享 收藏
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Deep sequencing of the LRRK2 gene in 14,002 individuals reveals evidence of purifying selection and independent origin of the p.Arg1628Pro mutation in Europe Rubio, Justin P.; Topp, Simon; Warren, Liling; St. Jean, Pamela L.; Wegmann, Daniel; Kessner, Darren; Novembre, John; Shen, Judong; Fraser, Dana; Aponte, Jennifer; Nangle, Keith; Cardon, Lon R.; Ehm, Margaret G.; Chissoe, Stephanie L.; Whittaker, John C.; Nelson, Matthew R.; Mooser, Vincent E. 分享 收藏
An 18-kDa Translocator Protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28 Owen, David R.; Yeo, Astrid J.; Gunn, Roger N.; Song, Kijoung; Wadsworth, Graham; Lewis, Andrew; Rhodes, Chris; Pulford, David J.; Bennacef, Idriss; Parker, Christine A.; StJean, Pamela L.; Cardon, Lon R.; Mooser, Vincent E.; Matthews, Paul M.; Rabiner, Eugenii A.; Rubio, Justin P. 分享 收藏
Association of the hemochromatosis gene with pazopanib-induced transaminase elevation in renal cell carcinoma Xu, Chun-Fang; Reck, Brian H.; Goodman, Vicki L.; Xue, Zhengyu; Huang, Lingkang; Barnes, Michael R.; Koshy, Beena; Spraggs, Colin F.; Mooser, Vincent E.; Cardon, Lon R.; Pandite, Lini N. 分享 收藏
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Genetic Variants Influencing Circulating Lipid Levels and Risk of Coronary Artery Disease 影响循环脂质水平和冠状动脉疾病风险的遗传变异 Waterworth, Dawn M.; Ricketts, Sally L.; Song, Kijoung; Chen, Li; Zhao, Jing Hua; Ripatti, Samuli; Aulchenko, Yurii S.; Zhang, Weihua; Yuan, Xin; Lim, Noha; Luan, Jian'an; Ashford, Sofie; Wheeler, Eleanor; Young, Elizabeth H.; Hadley, David; Thompson, John R.; Braund, Peter S.; Johnson, Toby; Struchalin, Maksim; Surakka, Ida; Luben, Robert; Khaw, Kay-Tee; Rodwell, Sheila A.; Loos, Ruth J. F.; Boekholdt, S. Matthijs; Inouye, Michael; Deloukas, Panagiotis; Elliott, Paul; Schlessinger, David; Sanna, Serena; Scuteri, Angelo; Jackson, Anne; Mohlke, Karen L.; Tuomilehto, Jaako; Roberts, Robert; Stewart, Alexandre; Kesaeniemi, Y. Antero; Mahley, Robert W.; Grundy, Scott M.; McArdle, Wendy; Cardon, Lon; Waeber, Gerard; Vollenweider, Peter; Chambers, John C.; Boehnke, Michael; Abecasis, Goncalo R.; Salomaa, Veikko; Jaervelin, Marjo-Riitta; Ruokonen, Aimo; Barroso, Ines; Epstein, Stephen E.; Hakonarson, Hakon H.; Rader, Daniel J.; Reilly, Muredach P.; Witteman, Jacqueline C. M.; Hall, Alistair S.; Samani, Nilesh J.; Strachan, David P.; Barter, Philip; van Duijn, Cornelia M.; Kooner, Jaspal S.; Peltonen, Leena; Wareham, Nicholas J.; McPherson, Ruth; Mooser, Vincent; Sandhu, Manjinder S. 分享 收藏
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Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism Xu, C-F; Reck, B. H.; Xue, Z.; Huang, L.; Baker, K. L.; Chen, M.; Chen, E. P.; Ellens, H. E.; Mooser, V. E.; Cardon, L. R.; Spraggs, C. F.; Pandite, L. 分享 收藏
Evidence for a major gene for bone mineral density in idiopathic osteoporotic families Cardon, LR; Garner, C; Bennett, ST; MacKay, IJ; Edwards, RM; Cornish, J; Hegde, M; Murray, MAF; Reid, IR; Cundy, T 分享 收藏
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