Peter P. Roller - Publications, H-index & Citations

Peter P. Roller

机构信息待补充

59H指数

279论文数

1.2W被引数

收录论文 38

发表时间

Design, synthesis, and characterization of a potent, nonpeptide, cell-permeable, bivalent smac mimetic that concurrently targets both the BIR2 and BIR3 domains in XIAP

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2007-11-14

208

OAAI

Sun, Haiying; Nikolovska-Coleska, Zaneta; Lu, Jianfeng; Meagher, Jennifer L.; Yang, Chao-Yie; Qiu, Su; Tomita, York; Ueda, Yumi; Jiang, Sheng; Krajewski, Krzysztof; Roller, Peter P.; Stuckey, Jeanne A.; Wang, Shaomeng

Design and synthesis of novel and potent inhibitors of the type II transmembrane serine protease, matriptase, based upon the sunflower trypsin inhibitor-1

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2007-11-07

PREAI

Li, Peng; Jiang, Sheng; Lee, Sheau-Ling; Lin, Cheng Yong; Johnson, Michael D.; Dickson, Robert B.; Michejda, Christopher J.; Roller, Peter P.

Design and synthesis of paclitaxel conjugated with an ErbB2-Recognizing pepticle, EC-1

BIOPOLYMERS

IF3.2

2007-08-21

PREAI

Li, Peng; Jiang, Sheng; Pero, Stephanie C.; Oligino, Lyn; Krag, David N.; Michejda, Christopher J.; Roller, Peter P.

Structure-based design of flavonoid compounds as a new class of small-molecule inhibitors of the anti-apoptotic bcl-2 proteins

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2007-06-07

OAAI

Tang, Guozhi; Ding, Ke; Nikolovska-Coleska, Zaneta; Yang, Chao-Yie; Qiu, Su; Shangary, Sanjeev; Wang, Renxiao; Guo, Jie; Gao, Wei; Meagher, Jennifer; Stuckey, Jeanne; Krajewski, Krzysztof; Jiang, Sheng; Roller, Peter P.; Wang, Shaomeng

Pyrogallol-based molecules as potent inhibitors of the antiapoptotic Bcl-2 proteins

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2007-03-23

OAAI

Tang, Guozhi; Yang, Chao-Yie; Nikolovska-Coleska, Zaneta; Guo, Jie; Qiu, Su; Wang, Renxiao; Gao, Wei; Wang, Guoping; Stuckey, Jeanne; Krajewski, Krzysztof; Jiang, Sheng; Roller, Peter P.; Wang, Shaomeng

Covalent binding of the natural antimicrobial peptide indolicidin to DNA abasic sites

NUCLEIC ACIDS RESEARCH

IF13.1

2006-09-22

143

OAAI

Marchand, Christophe; Krajewski, Krzysztof; Lee, Hsiu-Fang; Antony, Smitha; Johnson, Allison A.; Amin, Ronak; Roller, Peter P.; Kvaratskhelia, Mamuka; Pommier, Yves

Structure-based design of potent small-molecule inhibitors of anti-apoptotic Bcl-2 proteins

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2006-09-12

305

PREAI

Wang, Guoping; Nikolovska-Coleska, Zaneta; Yang, Chao-Yie; Wang, Renxiao; Tang, Guozhi; Guo, Jie; Shangary, Sanjeev; Qiu, Su; Gao, Wei; Yang, Dajun; Meagher, Jennifer; Stuckey, Jeanne; Krajewski, Krzysztof; Jiang, Sheng; Roller, Peter P.; Abaan, Hatice Ozel; Tomita, York; Wang, Shaomeng

Design and concise synthesis of fully protected analogues of L-γ-carboxyglutamic acid

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2006-08-15

PREAI

Jiang, Sheng; Li, Peng; Lai, Christopher C.; Kelley, James A.; Roller, Peter P.

Structure-based design of spiro-oxindoles as potent, specific small-molecule inhibitors of the MDM2-p53 interaction

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2006-05-13

769

PREAI

Ding, Ke; Lu, Yipin; Nikolovska-Coleska, Zaneta; Wang, Guoping; Qiu, Su; Shangary, Sanjeev; Gao, Wei; Qin, Dongguang; Stuckey, Jeanne; Krajewski, Krzysztof; Roller, Peter P.; Wang, Shaomeng

Discovery of a novel nonphosphorylated pentapeptide motif displaying high affinity for Grb2-SH2 domain by the utilization of 3′-substituted tyrosine derivatives

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2006-02-07

PREAI

Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, SM; Long, YQ

Structure-based design of potent non-peptide MDM2 inhibitors

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2005-06-30

687

PREAI

Ding, K; Lu, Y; Nikolovska-Coleska, Z; Qiu, S; Ding, YS; Gao, W; Stuckey, J; Krajewski, K; Roller, PP; Tomita, Y; Parrish, DA; Deschamps, JR; Wang, SM

Small nonphosphorylated Grb2-SH2 domain antagonists evaluated by surface resonance plasmon technology

BIOPOLYMERS

IF3.2

2005-01-19

PREAI

Lung, FDT; Chang, CW; Chong, MC; Liou, CC; Li, P; Peach, ML; Nicklaus, MC; Lou, BS; Roller, PP

Structure-based design of potent, conformationally constrained Smac mimetics

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2004-12-03

181

PREAI

Sun, HY; Nikolovska-Coleska, Z; Yang, CY; Xu, L; Liu, ML; Tomita, Y; Pan, HG; Yoshioka, Y; Krajewski, K; Roller, PP; Wang, SM

Structure-based discovery of nonpeptidic small organic compounds to block the T cell response to myelin basic protein

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2004-09-03

PREAI

Koehler, NKU; Yang, CY; Varady, J; Lu, YP; Wu, XW; Liu, M; Yin, DX; Bartels, M; Xu, BY; Roller, PP; Long, YQ; Li, P; Kattah, M; Cohn, ML; Moran, K; Tilley, E; Richert, JR; Wang, SM

Structure-based design, synthesis, and evaluation of conformationally constrained mimetics of the second mitochondria-derived activator of caspase that target the X-linked inhibitor of apoptosis protein/caspase-9 interaction site

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2004-07-16

148

PREAI

Sun, HY; Nikolovska-Coleska, Z; Yang, CY; Xu, L; Tomita, Y; Krajewski, K; Roller, PP; Wang, SM

Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XLAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2004-04-14

364