Guido Koch - Publications, H-index & Citations

Guido Koch

Novartis

28H指数

110论文数

2.5K被引数

收录论文 22

发表时间

Scale-Up Synthesis of IID572: A New β-Lactamase Inhibitor

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2020-05-14

PREAI

Furegati, Markus; Nocito, Sandro; Reck, Folkert; Casarez, Anthony; Simmons, Robert; Schuetz, Heiner; Koch, Guido

Design of Potent and Selective Covalent Inhibitors of Bruton's Tyrosine Kinase Targeting an Inactive Conformation 靶向无活性构象的布鲁顿酪氨酸激酶的有效和选择性共价抑制剂的设计

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2019-09-06

OAAI

Pulz, Robert; Angst, Daniela; Dawson, Janet; Gessier, Francois; Gutmann, Sascha; Hersperger, Rene; Hinniger, Alexandra; Janser, Philipp; Koch, Guido; Revesz, Laszlo; Vulpetti, Anna; Waelchli, Rudolf; Zimmerlin, Alfred; Cenni, Bruno

Late-Stage Functionalization of Peptides and Cyclopeptides Using Organozinc Reagents

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2019-05-09

PREAI

Leroux, Marcel; Vorherr, Thomas; Lewis, Ian; Schaefer, Michael; Koch, Guido; Karaghiosoff, Konstantin; Knochel, Paul

FROM THE ANALYST'S COUCH Demystifying industry-academia collaboration

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2019-01-16

PREAI

Gersdorf, Thomas; He, Vivianna Fang; Schlesinger, Ann; Koch, Guido; Ehrismann, Dominic; Widmer, Hans; von Krogh, Georg

Synthesis of Bicyclo[1.1.1]pentane Bioisosteres of Internal Alkynes and para-Disubstituted Benzenes from [1.1.1]Propellane

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2017-08-30

176

PREAI

Makarov, Ilya S.; Brocklehurst, Cara E.; Karaghiosoff, Konstantin; Koch, Guido; Knochel, Paul

Improving Nonspecific Binding and Solubility: Bicycloalkyl Groups and Cubanes as para-Phenyl Bioisosteres

CHEMMEDCHEM

IF3.4

2017-03-27

160

PREAI

Auberson, Yves P.; Brocklehurst, Cara; Furegati, Markus; Fessard, Thomas C.; Koch, Guido; Decker, Andrea; La Vecchia, Luigi; Briard, Emmanuelle

Construction of a 3D-shaped, natural product like fragment library by fragmentation and diversification of natural products 通过天然产物的片段化和多样化构建3d形状的天然产物样片段库

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2017-02-01

PREAI

Prescher, Horst; Koch, Guido; Schuhmann, Tim; Ertl, Peter; Bussenault, Alex; Glick, Meir; Dix, Ina; Petersen, Frank; Lizos, Dimitrios E.

A segmented flow platform for on-demand medicinal chemistry and compound synthesis in oscillating droplets

CHEMICAL COMMUNICATIONS

IF4.2

2017-01-01

PREAI

Hwang, Ye-Jin; Coley, Connor W.; Abolhasani, Milad; Marzinzik, Andreas L.; Koch, Guido; Spanka, Carsten; Lehmann, Hansjoerg; Jensen, Klavs F.

Multidimensional De Novo Design Reveals 5-HT2B Receptor-Selective Ligands

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2014-12-04

PREAI

Rodrigues, Tiago; Hauser, Nadine; Reker, Daniel; Reutlinger, Michael; Wunderlin, Tiffany; Hamon, Jacques; Koch, Guido; Schneider, Gisbert

Batch versus Flow Photochemistry: A Revealing Comparison of Yield and Productivity

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2014-09-26

177

OAAI

Elliott, Luke D.; Knowles, Jonathan P.; Koovits, Paul J.; Maskill, Katie G.; Ralph, Michael J.; Lejeune, Guillaume; Edwards, Lee J.; Robinson, Richard I.; Clemens, Ian R.; Cox, Brian; Pascoe, David D.; Koch, Guido; Eberle, Martin; Berry, Malcolm B.; Booker-Milburn, Kevin I.

Rethinking leadership in drug discovery projects 重新思考药物发现项目中的领导力

DRUG DISCOVERY TODAY

IF7.5

2012-12-01

PREAI

Schneider, Andreas; Erden, Zeynep; Widmer, Hans; Koch, Guido; Bill, Christine; von Krogh, Georg

Enantioselective hydrogenation of imines with chiral (phosphanodihydrooxazole)iridium catalysts 手性 (磷酸氢恶唑) 铱催化剂对亚胺的对映选择性氢化

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2006-01-20

249

PREAI

Schnider, P; Koch, G; Pretot, R; Wang, GZ; Bohnen, FM; Kruger, C; Pfaltz, A

A formal synthesis of (+)-discodermolide

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2005-03-16

PREAI

Loiseleur, O; Koch, G; Cercus, J; Schürch, F

N-H insertion reactions of primary ureas: The synthesis of highly substituted imidazolones and imidazoles from diazocarbonyls

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2004-11-10

PREAI

Lee, SH; Yoshida, K; Matsushita, H; Clapham, B; Koch, G; Zimmermann, J; Janda, KD

A practical building block for the synthesis of discodermolide

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2004-05-26

PREAI

Loiseleur, O; Koch, G; Wagner, T

Large-scale synthesis of the anti-cancer marine natural product (+)-discodermolide.: Part 3:: Synthesis of fragment C15-21

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2003-12-04

PREAI

Mickel, SJ; Sedelmeier, GH; Niederer, D; Schuerch, F; Koch, G; Kuesters, E; Daeffler, R; Osmani, A; Seeger-Weibel, M; Schmid, E; Hirni, A; Schaer, K; Gamboni, R

Large-scale synthesis of the anti-cancer marine natural product (+)-discodermolide.: Part 2:: Synthesis of fragments C1-6 and C9-14

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2003-12-04

PREAI

Mickel, SJ; Sedelmeier, GH; Niederer, D; Schuerch, F; Grimler, D; Koch, G; Daeffler, R; Osmani, A; Hirni, A; Schaer, K; Gamboni, R

Rhodium carbenoid N-H insertion reactions of primary ureas: Solution and solid-phase synthesis of imidazolones

ORGANIC LETTERS

IF5

2003-01-23

PREAI

Lee, SH; Clapham, B; Koch, G; Zimmermann, J; Janda, KD