未登录 High-Throughput Proteomics Sample Preparation Using a 96-Channel Pipettor and Magnetic Pin Device 使用96通道移液器和磁力针装置的高通量蛋白质组学样品制备 Roumelioti, Georgia; Montoya, Alex; Fisher, Gemma L. M.; Navarro, Eneko Pascual; Woods, Angela; Bennett, Jane; Navaratnam, Naveenan; Gonzalez-Carvajal, Oliver; Birch, Jodie; Pyman, Elizabeth; Yu, Sijia; Gruevska, Aleksandra; Vuillemenot, Luc-Alban; Lushchak, Oleh; Hall, Zoe; Barr, Alexis R.; Speck, Christian; Vernia, Santiago; Scott, William R.; Gil, Jesus; Aragon, Luis; Fets, Louise; Carling, David; Shliaha, Pavel V. 分享 收藏
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Interleukin 11 therapy causes acute left ventricular dysfunction Sweeney, Mark; O'Fee, Katie; Villanueva-Hayes, Chelsie; Rahman, Ekhlas; Lee, Michael; Tam, Chung Nga; Pascual-Navarro, Eneko; Maatz, Henrike; Lindberg, Eric L.; Vanezis, Konstantinos; Ramachandra, Chrishan J.; Andrew, Ivan; Jennings, Emma R.; Lim, Wei-Wen; Widjaja, Anissa A.; Carling, David; Hausenloy, Derek J.; Huebner, Norbert; Barton, Paul J. R.; Cook, Stuart A. 分享 收藏
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The CDK7 inhibitor CT7001 (Samuraciclib) targets proliferation pathways to inhibit advanced prostate cancer (vol 128, pg 2326, 2023) Constantin, Theodora A.; Varela-Carver, Anabel; Greenland, Kyle K.; de Almeida, Gilberto Serrano; Olden, Ellen; Penfold, Lucy; Ang, Simon; Ormrod, Alice; Leach, Damien A.; Lai, Chun-Fui; Ainscow, Edward K.; Bahl, Ash K.; Carling, David; Fuchter, Matthew J.; Ali, Simak; Bevan, Charlotte L. 分享 收藏
The CDK7 inhibitor CT7001 (Samuraciclib) targets proliferation pathways to inhibit advanced prostate cancer Constantin, Theodora A.; Varela-Carver, Anabel; Greenland, Kyle K.; de Almeida, Gilberto Serrano; Olden, Ellen; Penfold, Lucy; Ang, Simon; Ormrod, Alice; Leach, Damien A.; Lai, Chun-Fui; Ainscow, Edward K.; Bahl, Ash K.; Carling, David; Fuchter, Matthew J.; Ali, Simak; Bevan, Charlotte L. 分享 收藏
AMPK activation protects against prostate cancer by inducing a catabolic cellular state AMPK激活通过诱导分解代谢细胞状态来预防前列腺癌 Penfold, Lucy; Woods, Angela; Pollard, Alice E.; Arizanova, Julia; Pascual-Navarro, Eneko; Muckett, Phillip J.; Dore, Marian H.; Montoya, Alex; Whilding, Chad; Fets, Louise; Mokochinski, Joao; Constantin, Theodora A.; Varela-Carver, Anabel; Leach, Damien A.; Bevan, Charlotte L.; Niktin, Alexander Yu.; Hall, Zoe; Carling, David 分享 收藏
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AMP-activated kinase regulates cytoplasmic HuR Wang, W; Fan, J; Yang, X; Fürer-Galban, S; de Silanes, IL; von Kobbe, C; Guo, J; Georas, SN; Foufelle, F; Hardie, DG; Carling, D; Gorospe, M 分享 收藏
Hypoaminoacidemia underpins glucagon-mediated energy expenditure and weight loss Hope, David C. D.; Hinds, Charlotte E.; Lopes, Tatiana; Vincent, Matthew L.; V. Shrewsbury, Jed; Yu, Arthur T. C.; Davies, Iona; Scott, Rebecca; Jones, Ben; Murphy, Kevin G.; Minnion, James S.; Sardini, Alessandro; Carling, David; Lutz, Thomas A.; Bloom, Stephen R.; Tan, Tricia M. M.; Owen, Bryn M. 分享 收藏
Hepatocyte cholesterol content modulates glucagon receptor signalling McGlone, Emma Rose; Ansell, T. Bertie; Dunsterville, Cecilia; Song, Wanling; Carling, David; Tomas, Alejandra; Bloom, Stephen R.; Sansom, Mark S. P.; Tan, Tricia; Jones, Ben 分享 收藏
Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase 急性和慢性刺激AMP激活的蛋白激酶对调节胰岛素分泌的相反作用 Nguyen-Tu, Marie-Sophie; Harris, Joseph; Martinez-Sanchez, Aida; Chabosseau, Pauline; Hu, Ming; Georgiadou, Eleni; Pollard, Alice; Otero, Pablo; Lopez-Noriega, Livia; Leclerc, Isabelle; Sakamoto, Kei; Schmoll, Dieter; Smith, David M.; Carling, David; Rutter, Guy A. 分享 收藏
Indisulam targets RNA splicing and metabolism to serve as a therapeutic strategy for high-risk neuroblastoma Nijhuis, Anke; Sikka, Arti; Yogev, Orli; Herendi, Lili; Balcells, Cristina; Ma, Yurui; Poon, Evon; Eckold, Clare; Valbuena, Gabriel N.; Xu, Yuewei; Liu, Yusong; da Costa, Barbara Martins; Gruet, Michael; Wickremesinghe, Chiharu; Benito, Adrian; Kramer, Holger; Montoya, Alex; Carling, David; Want, Elizabeth J.; Jamin, Yann; Chesler, Louis; Keun, Hector C. 分享 收藏
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Direct AMPK Activation Corrects NASH in Rodents Through Metabolic Effects and Direct Action on Inflammation and Fibrogenesis 直接AMPK激活通过代谢作用和对炎症和纤维发生的直接作用来纠正啮齿动物的NASH Gluais-Dagorn, Pascale; Foretz, Marc; Steinberg, Gregory R.; Batchuluun, Battsetseg; Zawistowska-Deniziak, Anna; Lambooij, Joost M.; Guigas, Bruno; Carling, David; Monternier, Pierre-Axel; Moller, David E.; Bolze, Sebastien; Hallakou-Bozec, Sophie 分享 收藏
Direct small molecule ADaM-site AMPK activators reveal an AMPKg3-independent mechanism for blood glucose lowering Jorgensen, Nicolas O.; Kjobsted, Rasmus; Larsen, Magnus R.; Birk, Jesper B.; Andersen, Nicoline R.; Albuquerque, Bina; Schjerling, Peter; Miller, Russell; Carling, David; Pehmoller, Christian K.; Wojtaszewski, Jorgen F. P. 分享 收藏