未登录 Hit and lead criteria in drug discovery for infectious diseases of the developing world Katsuno, Kei; Burrows, Jeremy N.; Duncan, Ken; van Huijsduijnen, Rob Hooft; Kaneko, Takushi; Kita, Kiyoshi; Mowbray, Charles E.; Schmatz, Dennis; Warner, Peter; Slingsby, B. T. 分享 收藏
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Discovery of the Development Candidate N-tert-Butyl Nodulisporamide: A Safe and Efficacious Once Monthly Oral Agent for the Control of Fleas and Ticks on Companion Animals Meinke, Peter T.; Colletti, Steven L.; Fisher, Michael H.; Wyvratt, Matthew J.; Shih, Thomas L.; Ayer, Michelle B.; Li, Chunshi; Lim, Julie; Ok, Dong; Salva, Steve; Warmke, Lynn M.; Zakson, Michelle; Michael, Bruce F.; deMontigny, Pierre; Ostlind, Dan A.; Fink, David; Drag, Marlene; Schmatz, Dennis M.; Shoop, Wesley L. 分享 收藏
Synthesis and biological activity of imidazopyridine anticoccidial agents: Part II Scribner, Andrew; Dennis, Richard; Lee, Shuliang; Ouvry, Gilles; Perrey, David; Fisher, Michael; Wyvratt, Matthew; Leavitt, Penny; Liberator, Paul; Gurnett, Anne; Brown, Chris; Mathew, John; Thompson, Donald; Schmatz, Dennis; Biftu, Tesfaye 分享 收藏
Synthesis and biological activity of imidazopyridine anticoccidial agents: Part I Scribner, Andrew; Dennis, Richard; Hong, Jean; Lee, Shuliang; McIntyre, Donald; Perrey, David; Feng, Dennis; Fisher, Michael; Wyvratt, Matthew; Leavitt, Penny; Liberator, Paul; Gurnett, Anne; Brown, Chris; Mathew, John; Thompson, Donald; Schmatz, Dennis; Biftu, Tesfaye 分享 收藏
Discovery of FabH/FabF inhibitors from natural products Young, K; Jayasuriya, H; Ondeyka, JG; Herath, K; Zhang, CW; Kodali, S; Galgoci, A; Painter, R; Brown-Driver, V; Yamamoto, R; Silver, LL; Zheng, YC; Ventura, JI; Sigmund, J; Ha, S; Basilio, A; Vicente, F; Tormo, JR; Pelaez, F; Youngman, P; Cully, D; Barrett, JF; Schmatz, D; Singh, SB; Wang, J 分享 收藏
The discovery of moriniafungin, a novel sordarin derivative produced by Morinia pestalozzioides Basilio, A; Justice, M; Harris, G; Bills, G; Collado, J; de la Cruz, M; Diez, MT; Hernandez, P; Liberator, P; Kahn, JN; Pelaez, F; Platas, G; Schmatz, D; Shastry, M; Tormo, JR; Andersen, GR; Vicente, F 分享 收藏
Anthrax lethal factor inhibition Shoop, WL; Xiong, Y; Wiltsie, J; Woods, A; Guo, J; Pivnichny, JV; Felcetto, T; Michael, BF; Bansal, A; Cummings, RT; Cunningham, BR; Friedlander, AM; Douglas, CM; Patel, SB; Wisniewski, D; Scapin, G; Salowe, SP; Zaller, DM; Chapman, KT; Scolnick, EM; Schmatz, DM; Bartizal, K; MacCoss, M; Hermes, JD 分享 收藏
Determination of selectivity and efficacy of fatty acid synthesis inhibitors Kodali, S; Galgoci, A; Young, K; Painter, R; Silver, LL; Herath, KB; Singh, SB; Cully, D; Barrett, JF; Schmatz, D; Wang, J 分享 收藏
Hybrid-designed inhibitors of p38 MAP kinase utilizing N-arylpyridazinones Colletti, SL; Frie, JL; Dixon, EC; Singh, SB; Choi, BK; Scapin, G; Fitzgerald, CE; Kumar, S; Nichols, EA; O'Keefe, SJ; O'Neill, EA; Porter, G; Samuel, K; Schmatz, DM; Schwartz, CD; Shoop, WL; Thompson, CM; Thompson, JE; Wang, RX; Woods, A; Zaller, DM; Doherty, JB 分享 收藏
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Purification and molecular characterization of cGMP-dependent protein kinase from apicomplexan parasites - A novel chemotherapeutic target Gurnett, AM; Liberator, PA; Dulski, PM; Salowe, SP; Donald, RGK; Anderson, JW; Wiltsie, J; Diaz, CA; Harris, G; Chang, B; Darkin-Rattray, SJ; Nare, B; Crumley, T; Blum, PS; Misura, AS; Tamas, T; Sardana, MK; Yuan, J; Biftu, T; Schmatz, DM 分享 收藏
Structure and chemistry of apicidins, a class of novel cyclic tetrapeptides without a terminal α-keto epoxide as inhibitors of histone deacetylase with potent antiprotozoal activities Singh, SB; Zink, DL; Liesch, JM; Mosley, RT; Dombrowski, AW; Bills, GF; Darkin-Rattray, SJ; Schmatz, DM; Goetz, MA 分享 收藏
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Synthesis of nodulisporic acid 2-oxazoles and 2-thiazoles Berger, R; Shoop, WL; Pivnichny, JV; Warmke, LM; Zakson-Aiken, M; Owens, KA; deMontigny, P; Schmatz, DM; Wyvratt, MJ; Fisher, MH; Meinke, PT; Colletti, SL 分享 收藏
Structure, histone deacetylase, and antiprotozoal activities of apicidins B and C, congeners of apicidin with proline and valine substitutions Singh, SB; Zink, DL; Liesch, JM; Dombrowski, AW; Darkin-Rattray, SJ; Schmatz, DM; Goetz, MA 分享 收藏
Drug-resistant Drosophila indicate glutamate-gated chloride channels are targets for the antiparasitics nodulisporic acid and ivermectin Kane, NS; Hirschberg, B; Qian, S; Hunt, D; Thomas, B; Brochu, R; Ludmerer, SW; Zheng, YC; Smith, M; Arena, JP; Cohen, CJ; Schmatz, D; Warmke, J; Cully, DF 分享 收藏
Synthesis of apicidin-derived quinolone derivatives: Parasite-selective histone deacetylase inhibitors and antiproliferative agents Meinke, PT; Colletti, SL; Doss, G; Myers, RW; Gurnett, AM; Dulski, PM; Darkin-Rattray, SJ; Allocco, JJ; Galuska, S; Schmatz, DM; Wyvratt, MJ; Fisher, MH 分享 收藏
Efficacy of MK-991 (L-743,872), a semisynthetic pneumocandin, in murine models of Pneumocystis carinii Powles, MA; Liberator, P; Anderson, J; Karkhanis, Y; Dropinski, JF; Bouffard, FA; Balkovec, JM; Fujioka, H; Aikawa, M; McFadden, D; Schmatz, D 分享 收藏
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