未登录A Phase 2, Randomized, Multicenter, Placebo-Controlled, Proof-of-Concept Trial of Oral Fexinidazole in Adults With Chronic Indeterminate Chagas Disease
Torrico, Faustino; Gascon, Joaquim; Ortiz, Lourdes; Pinto, Jimy; Rojas, Gimena; Palacios, Alejandro; Barreira, Fabiana; Blum, Bethania; Schijman, Alejandro Gabriel; Vaillant, Michel; Strub-Wourgaft, Nathalie; Pinazo, Maria Jesus; Bilbe, Graeme; Ribeiro, Isabela
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收藏The Pandemic Response Box Accelerating Drug Discovery Efforts after Disease Outbreaks
Samby, Kirandeep; Besson, Dominique; Dutta, Anirban; Patra, Buddhadev; Doy, Angelique; Glossop, Paul; Mills, James; Whitlock, Gavin; van Huijsduijnen, Rob Hooft; Monaco, Alessandra; Bilbe, Graeme; Mowbray, Charles; Perry, Benjamin; Adam, Anna; Wells, Timothy N. C.; Willis, Paul A.
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收藏Tres Cantos Open Lab: celebrating a decade of innovation in collaboration to combat endemic infectious diseases COMMENT
Calderon, Felix; Ballell, Lluis; Barros, David; Bilbe, Graeme; Cammack, Nicholas; Gabarro, Raquel; Halsey, Audra; Heaton, Penny M.; Kang, Gagandeep; Mizrahi, Valerie; Nathan, Carl; Strange, Mike E.; Williams, Pauline M.; Winzeler, Elizabeth A.; Fairlamb, Alan H.
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收藏New regimens of benznidazole monotherapy and in combination with fosravuconazole for treatment of Chagas disease (BENDITA): a phase 2, double-blind, randomised trial
Torrico, Faustino; Gascon, Joaquim; Barreira, Fabiana; Blum, Bethania; Almeida, Igor C.; Alonso-Vega, Cristina; Barboza, Tayna; Bilbe, Graeme; Correia, Erika; Garcia, Wilson; Ortiz, Lourdes; Parrado, Rudy; Carlos Ramirez, Juan; Ribeiro, Isabela; Strub-Wourgaft, Nathalie; Vaillant, Michel; Sosa-Estani, Sergio
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收藏Implications of asymptomatic infection for the natural history of selected parasitic tropical diseases
Alvar, Jorge; Alves, Fabiana; Bucheton, Bruno; Burrows, Louise; Buscher, Philippe; Carrillo, Eugenia; Felger, Ingrid; Huebner, Marc P.; Moreno, Javier; Pinazo, Maria-Jesus; Ribeiro, Isabela; Sosa-Estani, Sergio; Specht, Sabine; Tarral, Antoine; Wourgaft, Nathalie Strub; Bilbe, Graeme
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收藏CpG ODN D35 improves the response to abbreviated low-dose pentavalent antimonial treatment in non-human primate model of cutaneous leishmaniasisCpG ODN D35可改善非人灵长类动物皮肤利什曼病模型对小剂量五价锑治疗的反应
Thacker, Seth G.; McWilliams, Ian L.; Bonnet, Beatrice; Halie, Lydia; Beaucage, Serge; Rachuri, Swaksha; Dey, Ranadhir; Duncan, Robert; Modabber, Farrokh; Robinson, Stephen; Bilbe, Graeme; Arana, Byron; Verthelyi, Daniela
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收藏Quantifying the Infectiousness of Post-Kala-Azar Dermal Leishmaniasis Toward Sand Flies量化后黑热病对沙蝇的传染性
Mondal, Dinesh; Bern, Caryn; Ghosh, Debashis; Rashid, Masud; Molina, Ricardo; Chowdhury, Rajashree; Nath, Rupen; Ghosh, Prakash; Chapman, Lloyd A. C.; Alim, Abdul; Bilbe, Graeme; Alvar, Jorge
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收藏Recent Development of Visceral Leishmaniasis Treatments: Successes, Pitfalls, and Perspectives内脏利什曼病治疗的最新进展: 成功,陷阱和前景
Alves, Fabiana; Bilbe, Graeme; Blesson, Severine; Goyal, Vishal; Monnerat, Severine; Mowbray, Charles; Ouattara, Gina Muthoni; Pecoul, Bernard; Rijal, Suman; Rode, Joelle; Solomos, Alexandra; Strub-Wourgaft, Nathalie; Wasunna, Monique; Wells, Susan; Zijlstra, Eduard E.; Arana, Byron; Alvar, Jorge
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收藏AQW051, a novel, potent and selective α7 nicotinic ACh receptor partial agonist: pharmacological characterization and phase I evaluation
Feuerbach, Dominik; Pezous, Nicole; Weiss, Markus; Shakeri-Nejad, Kasra; Lingenhoehl, Kurt; Hoyer, Daniel; Hurth, Konstanze; Bilbe, Graeme; Pryce, Christopher R.; McAllister, Kevin; Chaperon, Frederique; Kucher, Klaus; Johns, Donald; Blaettler, Thomas; Lopez Lopez, Cristina
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收藏AFQ056/mavoglurant, a novel clinically effective mGluR5 antagonist: Identification, SAR and pharmacological characterizationAFQ056/mavoglurant,一种新型临床有效的mGluR5拮抗剂: 鉴定,SAR和药理学表征
Vranesic, Ivo; Ofner, Silvio; Flor, Peter Josef; Bilbe, Graeme; Bouhelal, Rochdi; Enz, Albert; Desrayaud, Sandrine; McAllister, Kevin; Kuhn, Rainer; Gasparini, Fabrizio
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收藏Mutant huntingtin fragmentation in immune cells tracks Huntington's disease progression
Weiss, Andreas; Traeger, Ulrike; Wild, Edward J.; Grueninger, Stephan; Farmer, Ruth; Landles, Christian; Scahil, Rachael I.; Lahiri, Nayana; Haider, Salman; Macdonald, Douglas; Frost, Chris; Bates, Gillian P.; Bilbe, Graeme; Kuhn, Rainer; Andre, Ralph; Tabrizi, Sarah J.
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收藏Metabotropic glutamate receptor type 5 in levodopa-induced motor complications
Ouattara, Bazoumana; Gregoire, Laurent; Morissette, Marc; Gasparini, Fabrizio; Vranesic, Ivo; Bilbe, Graeme; Johns, Donald R.; Rajput, Alex; Hornykiewicz, Oleh; Rajput, Ali H.; Gomez-Mancilla, Baltazar; Di Paolo, Therese
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收藏The acute antiparkinsonian and antidyskinetic effect of AFQ056, a novel metabotropic glutamate receptor type 5 antagonist, in L-Dopa-treated parkinsonian monkeys
Gregoire, Laurent; Morin, Nicolas; Ouattara, Bazoumana; Gasparini, Fabrizio; Bilbe, Graeme; Johns, Donald; Vranesic, Ivo; Sahasranaman, Srikumar; Gomez-Mancilla, Baltazar; Di Paolo, Therese
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收藏Epigenetic Modification of the FMR1 Gene in Fragile X Syndrome Is Associated with Differential Response to the mGluR5 Antagonist AFQ056
Jacquemont, Sebastien; Curie, Aurore; des Portes, Vincent; Torrioli, Maria Giulia; Berry-Kravis, Elizabeth; Hagerman, Randi J.; Ramos, Feliciano J.; Cornish, Kim; He, Yunsheng; Paulding, Charles; Neri, Giovanni; Chen, Fei; Hadjikhani, Nouchine; Martinet, Danielle; Meyer, Joanne; Beckmann, Jacques S.; Delange, Karine; Brun, Amandine; Bussy, Gerald; Gasparini, Fabrizio; Hilse, Talita; Floesser, Annette; Branson, Janice; Bilbe, Graeme; Johns, Donald; Gomez-Mancilla, Baltazar
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收藏Region-specific transcriptional changes following the three antidepressant treatments electro convulsive therapy, sleep deprivation and fluoxetine
Conti, B.; Maier, R.; Barr, A. M.; Morale, M. C.; Lu, X.; Sanna, P. P.; Bilbe, G.; Hoyer, D.; Bartfai, T.
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