未登录 Effects of teclistamab and talquetamab on soluble BCMA levels in patients with relapsed/refractory multiple myeloma Girgis, Suzette; Lin, Shun Xin Wang; Pillarisetti, Kodandaram; Verona, Raluca; Vieyra, Diego; Casneuf, Tineke; Fink, Damien; Miao, Xin; Chen, Yang; Stephenson, Tara; Banerjee, Arnob; Hilder, Brandi W.; Russell, Jeffery; Infante, Jeffrey; Elsayed, Yusri; Smit, Jennifer; Goldberg, Jenna D. 分享 收藏
Translational Modeling Predicts Efficacious Therapeutic Dosing Range of Teclistamab for Multiple Myeloma (June, 10.1007/s11523-022-00893-y, 2022) Girgis, Suzette; Lin, Shun Xin Wang; Pillarisetti, Kodandaram; Banerjee, Arnob; Stephenson, Tara; Ma, Xuewen; Shetty, Shoba; Yang, Tong-Yuan; Hilder, Brandi W.; Jiao, Qun; Hanna, Brett; Adams, Homer C., III; Sun, Yu-Nien; Sharma, Amarnath; Smit, Jennifer; Infante, Jeffrey R.; Goldberg, Jenna D.; Elsayed, Yusri 分享 收藏
Translational Modeling Predicts Efficacious Therapeutic Dosing Range of Teclistamab for Multiple Myeloma Girgis, Suzette; Lin, Shun Xin Wang; Pillarisetti, Kodandaram; Banerjee, Arnob; Stephenson, Tara; Ma, Xuewen; Shetty, Shoba; Yang, Tong-Yuan; Hilder, Brandi W.; Jiao, Qun; Hanna, Brett; Adams, Homer; Sun, Yu-Nien; Sharma, Amarnath; Smit, Jennifer; Infante, Jeffrey R.; Goldberg, Jenna D.; Elsayed, Yusri 分享 收藏
Phase I Trial of ALRN-6924, a Dual Inhibitor of MDMX and MDM2, in Patients with Solid Tumors and Lymphomas Bearing Wild-type TP53 (vol 27, pg 5236, 2021) Saleh, Mansoor N.; Patel, Manish R.; Bauer, Todd M.; Goel, Sanjay; Falchook, Gerald S.; Shapiro, Geoffrey I.; Chung, Ki Y.; Infante, Jeffrey R.; Conry, Robert M.; Rabinowits, Guilherme; Hong, David S.; Wang, Judy S.; Steidl, Ulrich; Walensky, Loren D.; Naik, Gurudatta; Guerlavais, Vincent; Vukovic, Vojislav; Annis, D. Allen; Aivado, Manuel; Meric-Bernstam, Funda 分享 收藏
Teclistamab, a B-cell maturation antigenxCD3 bispecific antibody, in patients with relapsed or refractory multiple myeloma (MajesTEC-1): a multicentre, open-label, single-arm, phase 1 study Usmani, Saad Z.; Garfall, Alfred L.; van de Donk, Niels W. C. J.; Nahi, Hareth; San-Miguel, Jesus F.; Oriol, Albert; Rosinol, Laura; Chari, Ajai; Bhutani, Manisha; Karlin, Lionel; Benboubker, Lotfi; Pei, Lixia; Verona, Raluca; Girgis, Suzette; Stephenson, Tara; Elsayed, Yusri; Infante, Jeffrey; Goldberg, Jenna D.; Banerjee, Arnob; Mateos, Maria-Victoria; Krishnan, Amrita 分享 收藏
Phase 1 Trial of ALRN-6924, a Dual Inhibitor of MDMX and MDM2, in Patients with Solid Tumors and Lymphomas Bearing Wild-type TP53 Saleh, Mansoor N.; Patel, Manish R.; Bauer, Todd M.; Goel, Sanjay; Falchook, Gerald S.; Shapiro, Geoffrey, I; Chung, Ki Y.; Infante, Jeffrey R.; Conry, Robert M.; Rabinowits, Guilherme; Hong, David S.; Wang, Judy S.; Steidl, Ulrich; Naik, Gurudatta; Guerlavais, Vincent; Vukovic, Vojislav; Annis, D. Allen; Aivado, Manuel; Meric-Bernstam, Funda 分享 收藏
A Phase I Dose-Escalation and Expansion Study of Telaglenastat in Patients with Advanced or Metastatic Solid Tumors Harding, James J.; Telli, Melinda; Munster, Pamela; Voss, Martin H.; Infante, Jeffrey R.; DeMichele, Angela; Dunphy, Mark; Le, Mai H.; Molineaux, Chris; Orford, Keith; Parlati, Frank; Whiting, Sam H.; Bennett, Mark K.; Tannir, Nizar M.; Meric-Bernstam, Funda 分享 收藏
Safety and preliminary immunogenicity of JNJ-64041809, a live-attenuated, double-deleted Listeria monocytogenes-based immunotherapy, in metastatic castration-resistant prostate cancer 基于减毒双缺失单核细胞增生李斯特菌的免疫疗法JNJ-64041809在转移性去势抵抗性前列腺癌中的安全性和初步免疫原性 Drake, Charles G.; Pachynski, Russell K.; Subudhi, Sumit K.; McNeel, Douglas G.; Antonarakis, Emmanuel S.; Bauer, Todd M.; Lauer, Peter; Brockstedt, Dirk; Patricia, Daniel; Wade, Mark; Zudaire, Enrique; Bandyopadhyay, Nibedita; Parasrampuria, Dolly A.; Girgis, Suzette; Mason, Gary E.; Knoblauch, Roland E.; Stone, Nicole; Infante, Jeffrey R.; Gottardis, Marco M.; Fong, Lawrence 分享 收藏
Ciltacabtagene autoleucel, a B-cell maturation antigendirected chimeric antigen receptor T-cell therapy in patients with relapsed or refractory multiple myeloma (CARTITUDE-1): a phase 1b/2 open-label study Ciltacabtagene autoleucel，一种用于复发性或难治性多发性骨髓瘤 (CARTITUDE-1) 患者的b细胞成熟抗原导向的嵌合抗原受体T细胞疗法: 1b/2期开放标签研究 Berdeja, Jesus G.; Madduri, Deepu; Usmani, Saad Z.; Jakubowiak, Andrzej; Agha, Mounzer; Cohen, Adam D.; Stewart, A. Keith; Hari, Parameswaran; Htut, Myo; Lesokhin, Alexander; Deol, Abhinav; Munshi, Nikhil C.; O'Donnell, Elizabeth; Avigan, David; Singh, Indrajeet; Zudaire, Enrique; Yeh, Tzu-Min; Allred, Alicia J.; Olyslager, Yunsi; Banerjee, Arnob; Jackson, Carolyn C.; Goldberg, Jenna D.; Schecter, Jordan M.; Deraedt, William; Zhuang, Sen Hong; Infante, Jeffrey; Geng, Dong; Wu, Xiaoling; Carrasco-Alfonso, Marlene J.; Akram, Muhammad; Hossain, Farah; Rizvi, Syed; Fan, Frank; Lin, Yi; Martin, Thomas; Jagannath, Sundar 分享 收藏
First-in-human study of the safety, pharmacokinetics, and pharmacodynamics of first-in-class fatty acid synthase inhibitor TVB-2640 alone and with a taxane in advanced tumors 在晚期肿瘤中单独使用和与紫杉烷一起使用的第一类脂肪酸合酶抑制剂TVB-2640的安全性，药代动力学和药效学的首次人体研究 Falchook, Gerald; Infante, Jeffrey; Arkenau, Hendrik-Tobias; Patel, Manish R.; Dean, Emma; Borazanci, Erkut; Brenner, Andrew; Cook, Natalie; Lopez, Juanita; Pant, Shubham; Frankel, Arthur; Schmid, Peter; Moore, Kathleen; McCulloch, William; Grimmer, Katharine; O'Farrell, Marie; Kemble, George; Burris, Howard 分享 收藏
Safety and Clinical Activity of MEDI1873, a Novel GITR Agonist, in Advanced Solid Tumors Balmanoukian, Ani S.; Infante, Jeffrey R.; Aljumaily, Raid; Naing, Aung; Chintakuntlawar, Ashish V.; Rizvi, Naiyer A.; Ross, Helen J.; Gordon, Michael; Mallinder, Philip R.; Elgeioushi, Nairouz; Gonzalez-Garcia, Ignacio; Standifer, Nathan; Cann, Jennifer; Durham, Nicholas; Rahimian, Shahram; Kumar, Rakesh; Denlinger, Crystal S. 分享 收藏
Tebentafusp, A TCR/Anti-CD3 Bispecific Fusion Protein Targeting gp100, Potently Activated Antitumor Immune Responses in Patients with Metastatic Melanoma Middleton, Mark R.; McAlpine, Cheryl; Woodcock, Victoria K.; Corrie, Pippa; Infante, Jeffrey R.; Steven, Neil M.; Evans, Thomas R. Jeffry; Anthoney, Alan; Shoushtari, Alexander N.; Hamid, Omid; Gupta, Avinash; Vardeu, Antonella; Leach, Emma; Naidoo, Revashnee; Stanhope, Sarah; Lewis, Sion; Hurst, Jacob; O'Kelly, Ita; Sznol, Mario 分享 收藏
Avelumab as second-line therapy for metastatic, platinum-treated urothelial carcinoma in the phase Ib JAVELIN Solid Tumor study: 2-year updated efficacy and safety analysis Apolo, Andrea B.; Ellerton, John A.; Infante, Jeffrey R.; Agrawal, Manish; Gordon, Michael S.; Aljumaily, Raid; Gourdin, Theodore; Dirix, Luc; Lee, Keun-Wook; Taylor, Matthew H.; Schoeffski, Patrick; Wang, Ding; Ravaud, Alain; Manitz, Juliane; Pennock, Gregory; Ruisi, Mary; Gulley, James L.; Patel, Manish R. 分享 收藏
Immunologic and tumor responses of pegilodecakin with 5-FU/LV and oxaliplatin (FOLFOX) in pancreatic ductal adenocarcinoma (PDAC) Hecht, J. Randolph; Papadopoulos, Kyriakos P.; Falchook, Gerald S.; Patel, Manish R.; Infante, Jeffrey R.; Aljumaily, Raid; Wong, Deborah J.; Autio, Karen A.; Wainberg, Zev A.; Bauer, Todd M.; Javle, Milind; Pant, Shubham; Bendell, Johanna; Hung, Annie; Ratti, Navneet; VanVlasselaer, Peter; Verma, Rakesh; Leveque, Joseph; Rao, Sujata; Oft, Martin; Naing, Aung 分享 收藏
Amivantamab (JNJ-61186372), an EGFR-MET bispecific antibody, in combination with lazertinib, a 3rd-generation tyrosine kinase inhibitor (TKI), in advanced EGFR NSCLC Cho, B. C.; Lee, K. H.; Cho, E. K.; Kim, D-W.; Lee, J-S.; Han, J-Y.; Kim, S-W.; Spira, A.; Haura, E. B.; Sabari, J. K.; Sanborn, R. E.; Bauml, J. M.; Gomez, J. E.; Lorenzini, P.; Infante, J. R.; Xie, J.; Haddish-Berhane, N.; Thayu, M.; Knoblauch, R. E.; Park, K. 分享 收藏
Phase Ia Study of Anti-NaPi2b Antibody-Drug Conjugate Lifastuzumab Vedotin DNIB0600A in Patients with Non-Small Cell Lung Cancer and Platinum-Resistant Ovarian Cancer Gerber, David E.; Infante, Jeffrey R.; Gordon, Michael S.; Goldberg, Sarah B.; Martin, Miguel; Felip, Enriqueta; Martinez Garcia, Maria; Schiller, Joan H.; Spigel, David R.; Cordova, Julie; Westcott, Valerie; Wang, Yulei; Shames, David S.; Choi, YounJeong; Kahn, Robert; Dere, Randall C.; Samineni, Divya; Xu, Jian; Lin, Kedan; Wood, Katie; Royer-Joo, Stephanie; Lemahieu, Vanessa; Schuth, Eva; Vaze, Anjali; Maslyar, Daniel; Humke, Eric W.; Burris, Howard A., III 分享 收藏
Anti-PD-1 monoclonal antibody MEDI0680 in a phase I study of patients with advanced solid malignancies Naing, Aung; Infante, Jeffrey; Goel, Sanjay; Burris, Howard; Black, Chelsea; Marshall, Shannon; Achour, Ikbel; Barbee, Susannah; May, Rena; Morehouse, Chris; Pollizzi, Kristen; Song, Xuyang; Steele, Keith; Elgeioushi, Nairouz; Walcott, Farzana; Karakunnel, Joyson; LoRusso, Patricia; Weise, Amy; Eder, Joseph; Curti, Brendan; Oberst, Michael 分享 收藏
Multicenter Phase I Study of Erdafitinib (JNJ-42756493), Oral Pan-Fibroblast Growth Factor Receptor Inhibitor, in Patients with Advanced or Refractory Solid Tumors Bahleda, Rastislav; Italiano, Antoine; Hierro, Cinta; Mita, Alain; Cervantes, Andres; Chan, Nancy; Awad, Mark; Calvo, Emiliano; Moreno, Victor; Govindan, Ramaswamy; Spira, Alexander; Gonzalez, Martha; Zhong, Bob; Santiago-Walker, Ademi; Poggesi, Italo; Parekh, Trilok; Xie, Hong; Infante, Jeffrey; Tabernero, Josep 分享 收藏
Phase I study of the anti-endothelin B receptor antibody-drug conjugate DEDN6526A in patients with metastatic or unresectable cutaneous, mucosal, or uveal melanoma Sandhu, Shahneen; McNeil, Catriona M.; LoRusso, Patricia; Patel, Manish R.; Kabbarah, Omar; Li, Chunze; Sanabria, Sandra; Flanagan, W. Michael; Yeh, Ru-Fang; Brunstein, Flavia; Nazzal, Denise; Hicks, Rodney; Lemahieu, Vanessa; Meng, Raymond; Hamid, Omid; Infante, Jeffrey R. 分享 收藏
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