未登录Differences in methylation profiles between long-term survivors and short-term survivors of IDH-wild-type glioblastoma
van der Meulen, Matthijs; Ramos, Ronald C.; Voisin, Mathew R.; Patil, Vikas; Wei, Qingxia; Singh, Olivia; Climans, Seth A.; Kalidindi, Navya; Or, Rosemarylin; Aldape, Ken; Diamandis, Phedias; Munoz, David G.; Zadeh, Gelareh; Mason, Warren P. .png)
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收藏Pleomorphic xanthoastrocytoma is a heterogeneous entity with pTERT mutations prognosticating shorter survival多形性黄色星形细胞瘤是一种异质实体，具有pTERT突变，预后生存期较短Ebrahimi, Azadeh; Korshunov, Andrey; Reifenberger, Guido; Capper, David; Felsberg, Joerg; Trisolini, Elena; Pollo, Bianca; Calatozzolo, Chiara; Prinz, Marco; Staszewski, Ori; Schweizer, Leonille; Schittenhelm, Jens; Harter, Patrick N.; Paulus, Werner; Thomas, Christian; Kohlhof-Meinecke, Patricia; Seiz-Rosenhagen, Marcel; Milde, Till; Casalini, Belen M.; Suwala, Abigail; Wefers, Annika K.; Reinhardt, Annekathrin; Sievers, Philipp; Kramm, Christof M.; Etminam, Nima; Unterberg, Andreas; Wick, Wolfgang; Herold-Mende, Christel; Sturm, Dominik; Pfister, Stefan M.; Sill, Martin; Jones, David T. W.; Schrimpf, Daniel; Reuss, David E.; Aldape, Ken; Abdullaev, Zied; Sahm, Felix; von Deimling, Andreas; Stichel, Damian 分享 收藏 Non-IDH1-R132H IDH1/2 mutations are associated with increased DNA methylation and improved survival in astrocytomas, compared to IDH1-R132H mutations与IDH1-R132H突变相比，非R132H位点的IDH1/2突变在星形细胞瘤中表现为DNA甲基化水平升高和生存期延长。Tesileanu, C. Mircea S.; Vallentgoed, Wies R.; Sanson, Marc; Taal, Walter; Clement, Paul M.; Wick, Wolfgang; Brandes, Alba Ariela; Baurain, Jean Francais; Chinot, Olivier L.; Wheeler, Helen; Gill, Sanjeev; Griffin, Matthew; Rogers, Leland; Ruda, Roberta; Weller, Michael; McBain, Catherine; Reijneveld, Jaap; Enting, Roelien H.; Caparrotti, Francesca; Lesimple, Thierry; Clenton, Susan; Gijtenbeek, Anja; Lim, Elizabeth; de Vos, Filip; Mulholland, Paul J.; Taphoorn, Martin J. B.; de Heer, Iris; Hoogstrate, Youri; de Wit, Maurice; Boggiani, Lorenzo; Venneker, Sanne; Oosting, Jan; Bovee, Judith V. M. G.; Erridge, Sara; Vogelbaum, Michael A.; Nowak, Anna K.; Mason, Warren P.; Kros, Johan M.; Wesseling, Pieter; Aldape, Ken; Jenkins, Robert B.; Dubbink, Hendrikus J.; Baumert, Brigitta; Golfinopoulos, Vassilis; Gorlia, Thierry; van den Bent, Martin; French, Pim J. 分享 收藏 分享 收藏 Interim results from the CATNON trial (EORTC study 26053-22054) of treatment with concurrent and adjuvant temozolomide for 1p/19q non-co-deleted anaplastic glioma: a phase 3, randomised, open-label intergroup studyvan den Bent, Martin J.; Baumert, Brigitta; Erridge, Sara C.; Vogelbaum, Michael A.; Nowak, Anna K.; Sanson, Marc; Brandes, Alba Ariela; Clement, Paul M.; Baurain, Jean Francais; Mason, Warren P.; Wheeler, Helen; Chinot, Olivier L.; Gill, Sanjeev; Griffin, Matthew; Brachman, David G.; Taal, Walter; Ruda, Roberta; Weller, Michael; McBain, Catherine; Reijneveld, Jaap; Enting, Roelien H.; Weber, Damien C.; Lesimple, Thierry; Clenton, Susan; Gijtenbeek, Anja; Pascoe, Sarah; Herrlinger, Ulrich; Hau, Peter; Dhermain, Frederic; van Heuvel, Irene; Stupp, Roger; Aldape, Ken; Jenkins, Robert B.; Dubbink, Hendrikus Jan; Dinjens, Winand N. M.; Wesseling, Pieter; Nuyens, Sarah; Golfinopoulos, Vassilis; Gorlia, Thierry; Wick, Wolfgang; Kros, Johan M. 分享 收藏 Meningiomas induced by low-dose radiation carry structural variants of NF2 and a distinct mutational signatureSahm, Felix; Toprak, Umut H.; Huebschmann, Daniel; Kleinheinz, Kortine; Buchhalter, Ivo; Sill, Martin; Stichel, Damian; Schick, Matthias; Bewerunge-Hudler, Melanie; Schrimpf, Daniel; Zadeh, Gelareh; Aldape, Ken; Herold-Mende, Christel; Beck, Katja; Staszewski, Ori; Prinz, Marco; Ben Harosh, Carmit; Eils, Roland; Sturm, Dominik; Jones, David T. W.; Pfister, Stefan M.; Paulus, Werner; Ram, Zvi; Schlesner, Matthias; Grossman, Rachel; von Deimling, Andreas 分享 收藏 分享 收藏 cIMPACT-NOW (the consortium to inform molecular and practical approaches to CNS tumor taxonomy): a new initiative in advancing nervous system tumor classificationLouis, David N.; Aldape, Ken; Brat, Daniel J.; Capper, David; Ellison, David W.; Hawkins, Cynthia; Paulus, Werner; Perry, Arie; Reifenberger, Guido; Figarella-Branger, Dominique; Wesseling, Pieter; Batchelor, Tracy T.; Cairncross, J. Gregory; Pfister, Stefan M.; Rutkowski, Stefan; Weller, Michael; Wick, Wolfgang; von Deimling, Andreas 分享 收藏 Announcing cIMPACT-NOW: the Consortium to Inform Molecular and Practical Approaches to CNS Tumor TaxonomyLouis, David N.; Aldape, Ken; Brat, Daniel J.; Capper, David; Ellison, David W.; Hawkins, Cynthia; Paulus, Werner; Perry, Arie; Reifenberger, Guido; Figarella-Branger, Dominique; Wesseling, Pieter; Batchelor, Tracy T.; Cairncross, J. Gregory; Pfister, Stefan M.; Rutkowski, Stefan; Weller, Michael; Wick, Wolfgang; von Deimling, Andreas 分享 收藏 NRG oncology RTOG 0625: a randomized phase II trial of bevacizumab with either irinotecan or dose-dense temozolomide in recurrent glioblastomaGilbert, Mark R.; Pugh, Stephanie L.; Aldape, Ken; Sorensen, A. Gregory; Mikkelsen, Tom; Penas-Prado, Marta; Bokstein, Felix; Kwok, Young; Lee, R. Jeffrey; Mehta, Minesh 分享 收藏 分享 收藏 GliomaWeller, Michael; Wick, Wolfgang; Aldape, Ken; Brada, Michael; Berger, Mitchell; Pfister, Stefan M.; Nishikawa, Ryo; Rosenthal, Mark; Wen, Patrick Y.; Stupp, Roger; Reifenberger, Guido 分享 收藏 DISTINCT COPY NUMBER ALTERATIONS AND INCIDENCE OF CHROMOTHRIPSIS ASSOCIATED WITH GRADE AND PROGNOSIS IN IDH MUTANT AND WILD-TYPE GLIOMASColman, Howard; Cohen, Adam; Aldape, Ken; Sato, Mariko; Mason, Clint; Diefes, Kristin; Heathcock, Lindsey; Abegglen, Lisa; Shrieve, Dennis; Couldwell, William; Schiffman, Joshua 分享 收藏 分享 收藏 Mesenchymal high-grade glioma is maintained by the ID-RAP-1 axisNiola, Francesco; Zhao, Xudong; Singh, Devendra; Sullivan, Ryan; Castano, Angelica; Verrico, Antonio; Zoppoli, Pietro; Friedmann-Morvinski, Dinorah; Sulman, Erik; Barrett, Lindy; Zhuang, Yuan; Verma, Inder; Benezra, Robert; Aldape, Ken; Iavarone, Antonio; Lasorella, Anna 分享 收藏 A Revised RTOG Recursive Partitioning Analysis (RPA) Model for Glioblastoma Based Upon Multi-Platform Biomarker ProfilesChakravarti, A.; Wang, M.; Aldape, K.; Sulman, E.; Bredel, M.; Hegi, M.; Gilbert, M.; Curran, W.; Werner-Wasik, M.; Mehta, M. 分享 收藏 A Revised RTOG Recursive Partitioning Analysis (RPA) Model for Gliobtastoma Based Upon Multiplatform Biomarker ProfilesChakravarti, A.; Wang, M.; Aldape, K.; Sulman, E.; Bredel, M.; Hegi, M.; Gilbert, M.; Curran, W.; Werner-Wasik, M.; Mehta, M. 分享 收藏 Akt pathway genes classify GBM into 6 prognostic subgroups with different clinical and molecular featuresJoy, Anna M.; Ramesh, Archana; Smirnov, Ivan; Misra, Anjan; Shapiro, William; Phillips, Heidi; Aldape, Ken; Mills, Gordon; Kim, Seungchan; Feuerstein, Burt 分享 收藏 A prognostic gene expression signature in infratentorial ependymoma幕下室管膜瘤的预后基因表达特征Wani, Khalida; Armstrong, Terri S.; Vera-Bolanos, Elizabeth; Raghunathan, Aditya; Ellison, David; Gilbertson, Richard; Vaillant, Brian; Goldman, Stewart; Packer, Roger J.; Fouladi, Maryam; Pollack, Ian; Mikkelsen, Tom; Prados, Michael; Omuro, Antonio; Soffietti, Riccardo; Ledoux, Alicia; Wilson, Charmaine; Long, Lihong; Gilbert, Mark R.; Aldape, Ken 分享 收藏 分享 收藏 
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