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Clinical trial: A Phase 2 Randomised Platform Study to Assess Monotherapy and Combination Treatment Regimens in Metabolic Dysfunction-Associated Steatohepatitis 临床试验：一项评估代谢功能障碍相关脂肪性肝炎单药疗法和联合治疗方案的第2期随机平台研究 Frias, Juan; Schmouder, Robert; Lawitz, Eric; Zhang, Yiming; Zhou, Heng; Badman, Michael K.; Ukomadu, Chinweike; Weiss, H. Markus; Zack, Julia; Yadav, Brijesh; Martic, Miljen; Drakeford, Clive; Koo, Phillip; Naoumov, Nikolai V.; Greenbaum, Linda E. 分享 收藏
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Pharmacokinetics and Safety of Navitoclax in Hepatic Impairment Navitoclax的药代动力学和安全性研究（肝功能不全患者） Patel, Maulik; Potluri, Jalaja; Marbury, Thomas; Lawitz, Eric; Rondon, Juan Carlos; Hoffman, David M.; Siddani, Satya R.; Marsh, Kennan C.; Kim, Elaine J.; Uddin, Muhammad Erfan; Menon, Rajeev M.; Polepally, Akshanth R. 分享 收藏
Addressing the High and Rising Global Burden of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and Metabolic Dysfunction-Associated Steatohepatitis (MASH): From the Growing Prevalence to Payors' Perspective 解决代谢功能障碍相关的脂肪性肝病 (MASLD) 和代谢功能障碍相关的脂肪性肝炎 (MASH) 的全球高负担和不断上升: 从日益增长的患病率到支付方的角度 Younossi, Zobair M.; Razavi, Homie; Sherman, Michael; Allen, Alina M.; Anstee, Quentin M.; Cusi, Kenneth; Friedman, Scott L.; Lawitz, Eric; Lazarus, Jeffrey V.; Schuppan, Detlef; Romero-Gomez, Manuel; Schattenberg, Joern M.; Vos, Miriam B.; Wong, Vincent Wai-Sun; Ratziu, Vlad; Hompesch, Marcus; Sanyal, Arun J.; Loomba, Rohit 分享 收藏
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Efficacy, tolerability and pharmacokinetics of survodutide, aglucagon/glucagon-like peptide-1 receptor dual agonist,in cirrhosis 胰高血糖素/胰高血糖素样肽-1受体双重激动剂survodutide在肝硬化中的疗效，耐受性和药代动力学 Lawitz, Eric J.; Fraessdorf, Mandy; Neff, Guy W.; Schattenberg, Joern M.; Noureddin, Mazen; Alkhouri, Naim; Schmid, Bernhard; Andrews, Charles P.; Takacs, Istvan; Hussain, Samina Ajaz; Fenske, Wiebke K.; Gane, Edward J.; Hosseini-Tabatabaei, Azadeh; Sanyal, Arun J.; Mazo, Daniel F.; Younes, Ramy 分享 收藏
A Phase 2 Randomized Trial of Survodutide in MASH and Fibrosis Survodutide在MASH和纤维化中的2期随机试验 Sanyal, Arun J.; Bedossa, Pierre; Fraessdorf, Mandy; Neff, Guy W.; Lawitz, Eric; Bugianesi, Elisabetta; Anstee, Quentin M.; Hussain, Samina Ajaz; Newsome, Philip N.; Ratziu, Vlad; Hosseini-Tabatabaei, Azadeh; Schattenberg, Jorn M.; Noureddin, Mazen; Alkhouri, Naim; Younes, Ramy 分享 收藏
The effect of vitamin E and docosahexaenoic acid ethyl ester on Metabolic Dysfunction-Associated steatotic Liver Disease (MASLD)-A randomised, double-blind, placebo-controlled, parallel-group clinical trial (PUVENAFLD) Alkhouri, Naim; McCarthy, Deanna; Bayne, Anne-Cecile V.; Blonquist, Traci; Yurko-Mauro, Karin; Vuppalanchi, Raj; Lawitz, Eric; Chalasani, Naga 分享 收藏
Efficacy and Safety of Elafibranor in Primary Biliary Cholangitis Elafibranor在原发性胆汁性胆管炎中的疗效和安全性 Kowdley, Kris V.; Bowlus, Christopher L.; Levy, Cynthia; Akarca, Ulus S.; Alvares-da-Silva, Mario Reis; Andreone, Pietro; Arrese, Marco; Corpechot, Christophe; Francque, Sven M.; Heneghan, Michael A.; Invernizzi, Pietro; Jones, David; Kruger, Frederik C.; Lawitz, Eric; Mayo, Marlyn J.; Shiffman, Mitchell L.; Swain, Mark G.; Valera, Jose Miguel; Vargas, Victor; Vierling, John M.; Villamil, Alejandra; Addy, Carol; Dietrich, Julie; Germain, Jean-Michel; Mazain, Sarah; Rafailovic, Dragutin; Tadde, Bachirou; Miller, Benjamin; Shu, Jianfen; Zein, Claudia O.; Schattenberg, Jorn M. 分享 收藏
Artificial intelligence-assisted digital pathology for non-alcoholic steatohepatitis: current status and future directions 非酒精性脂肪性肝炎的人工智能辅助数字病理学: 现状和未来方向 Ratziu, Vlad; Hompesch, Marcus; Petitjean, Mathieu; Serdjebi, Cindy; Iyer, Janani S.; Parwani, Anil V.; Tai, Dean; Bugianesi, Elisabetta; Cusi, Kenneth; Friedman, Scott L.; Lawitz, Eric; Romero-Gomez, Manuel; Schuppan, Detlef; Loomba, Rohit; Paradis, Valerie; Behling, Cynthia; Sanyal, Arun J. 分享 收藏
Safety, pharmacokinetics and pharmacodynamics of obeticholic acid in subjects with fibrosis or cirrhosis from NASH Alkhouri, Naim; LaCerte, Carl; Edwards, Jeffrey; Poordad, Fred; Lawitz, Eric; Lee, Lois; Karan, Sharon; Sawhney, Sangeeta; Erickson, Mary; MacConell, Leigh; Zaru, Luna; Chen, Jianfen; Campagna, Jason 分享 收藏
A randomised Phase IIa trial of amine oxidase copper-containing 3 (AOC3) inhibitor BI 1467335 in adults with non-alcoholic steatohepatitis Newsome, Philip N.; Sanyal, Arun J.; Neff, Guy; Schattenberg, Joern M.; Ratziu, Vlad; Ertle, Judith; Link, Jasmin; Mackie, Alison; Schoelch, Corinna; Lawitz, Eric 分享 收藏
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Results from a new efficacy and safety analysis of the REGENERATE trial of obeticholic acid for treatment of pre-cirrhotic fibrosis due to non-alcoholic steatohepatitis Sanyal, Arun J.; Ratziu, Vlad; Loomba, Rohit; Anstee, Quentin M.; Kowdley, Kris, V; Rinella, Mary E.; Sheikh, Muhammad Y.; Trotter, James F.; Knapple, Whitfield; Lawitz, Eric J.; Abdelmalek, Manal F.; Newsome, Philip N.; Boursier, Jerome; Mathurin, Philippe; Dufour, Jean-Francois; Berrey, M. Michelle; Shiff, Steven J.; Sawhney, Sangeeta; Capozza, Thomas; Leyva, Rina; Harrison, Stephen A.; Younossi, Zobair M. 分享 收藏
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Efficacy and Safety of Sofosbuvir/Velpatasvir Plus Ribavirin in Patients with Hepatitis C Virus-Related Decompensated Cirrhosis Flamm, Steven; Lawitz, Eric; Borg, Brian; Charlton, Michael; Landis, Charles; Reddy, K. Rajender; Shiffman, Mitchell; Alsina, Angel; Chang, Charissa; Ravendhran, Natarajan; Hernandez, Candido; Hezode, Christophe; Scherbakovsky, Stacey; Mercier, Renee-Claude; Samuel, Didier 分享 收藏
A randomized, double-blind, placebo-controlled trial of aldafermin in patients with NASH and compensated cirrhosis Rinella, Mary E.; Lieu, Hsiao D.; Kowdley, Kris V.; Goodman, Zachary D.; Alkhouri, Naim; Lawitz, Eric; Ratziu, Vlad; Abdelmalek, Manal F.; Wong, Vincent Wai-Sun; Younes, Ziad H.; Sheikh, Aasim M.; Brannan, Donald; Freilich, Bradley; Membreno, Fernando; Sinclair, Marie; Melchor-Khan, Liza; Sanyal, Arun J.; Ling, Lei; Harrison, Stephen A. 分享 收藏
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