未登录 Correlation between tumor growth rate and survival in patients with metastatic breast cancer treated with trastuzumab deruxtecan 曲妥珠单抗德鲁替康治疗转移性乳腺癌患者中肿瘤生长速率与生存期的相关性 He, Philip; Gambhire, Dhiraj; Zhou, Haiming; Ma, Xiaoyang; Emura, Yoshihiro; Laadem, Abderrahmane; Leung, David; Bates, Susan; Fojo, Antonio Tito; Rixe, Olivier 分享 收藏
A First-in-Human Phase I Study of BXQ-350, a First-in-Class Sphingolipid Metabolism Regulator, in Patients with Advanced/Recurrent Solid Tumors or High-Grade Gliomas Rixe, Olivier; Villano, John L.; Wesolowski, Robert; Noonan, Anne M.; Puduvalli, Vinay K.; Wise-Draper, Trisha M.; Curry, Richard; Yilmaz, Emrullah; Cruze, Charlie; Ogretmen, Besim; Tapolsky, Gilles; Takigiku, Ray 分享 收藏
Phase 1 dose-escalation study of SEA-CD40: a non-fucosylated CD40 agonist, in advanced solid tumors and lymphomas SEA-CD40的1期剂量递增研究: 非岩藻糖基化CD40激动剂，用于晚期实体瘤和淋巴瘤 Coveler, Andrew L.; Smith, David C.; Phillips, Tycel; Curti, Brendan D.; Goel, Sanjay; Mehta, Amitkumar N.; Kuzel, Timothy M.; Markovic, Svetomir N.; Rixe, Olivier; Bajor, David L.; Gajewski, Thomas F.; Gutierrez, Martin; Lee, Hun Ju; Gopal, Ajay K.; Caimi, Paolo; Heath, Elisabeth, I; Thompson, John A.; Ansari, Sahar; Jacquemont, Celine; Topletz-Erickson, Ariel; Zhou, Peigen; Schmitt, Michael W.; Grilley-Olson, Juneko E. 分享 收藏
Phase IB Study of GITR Agonist Antibody TRX518 Singly and in Combination with Gemcitabine, Pembrolizumab, or Nivolumab in Patients with Advanced Solid Tumors GITR激动剂抗体TRX518单独或与吉西他滨，Pembrolizumab或Nivolumab联合治疗晚期实体瘤患者的IB期研究 Davar, Diwakar; Zappasodi, Roberta; Wang, Hong; Naik, Girish S.; Sato, Takami; Bauer, Todd; Bajor, David; Rixe, Olivier; Newman, Walter; Qi, Jingjing; Holland, Aliya; Wong, Phillip; Sifferlen, Lianna; Piper, Diane; Sirard, Cynthia A.; Merghoub, Taha; Wolchok, Jedd D.; Luke, Jason J. 分享 收藏
Phase II trial of the IDO pathway inhibitor indoximod plus pembrolizumab for the treatment of patients with advanced melanoma Zakharia, Yousef; McWilliams, Robert R.; Rixe, Olivier; Drabick, Joseph; Shaheen, Montaser F.; Grossmann, Kenneth F.; Kolhe, Ravindra; Pacholczyk, Rafal; Sadek, Ramses; Tennant, Lucinda L.; Smith, Christopher M.; Kennedy, Eugene P.; Link, Charles J., Jr.; Vahanian, Nicholas N.; Yu, Jiayi; Shen, Steven S.; Brincks, Erik L.; Rossi, Gabriela R.; Munn, David; Milhem, Mohammed 分享 收藏
SAFETY AND ANTITUMOR ACTIVITY OF INDOLEAMINE 2,3-DIOXYGENASE 1 (IDO-1) INHIBITOR KHK2455 IN COMBINATION WITH ANTI-CCR4 MONOCLONAL ANTIBODY MOGAMULIZUMAB IN PATIENTS WITH ADVANCED SOLID TUMORS Sahebjam, Solmaz; Muzaffar, Jameel; Yap, Timothy; Hong, David; Rixe, Olivier; Brown-Glaberman, Ursa; Varga, Andreea; Massard, Christophe; Baldini, Capucine; Efuni, Sergey; Kapelan, Barbara; Liu, Yi; Ogunmefun, Eniola; Tayama, Tomonori; Zhao, Henry; Healy, Denis; Latek, Robert; Nakashima, Daisuke; Yilmaz, Emrullah 分享 收藏
SEA-CD40 is a non-fucosylated anti-CD40 antibody with potent pharmacodynamic activity in preclinical models and patients with advanced solid tumors Neff-LaFord, Haley; Grilley-Olson, Juneko E.; Smith, David C.; Curti, Brendan; Goel, Sanjay; Kuzel, Timothy M.; Markovic, Svetomir N.; Rixe, Olivier; Bajor, David L.; Gajewski, Thomas F.; Gutierrez, Martin; Heath, Elisabeth I.; Thompson, John; Ansari, Sahar; Gardai, Shyra; Jacquemont, Celine; Schmitt, Michael; Coveler, Andrew L. 分享 收藏
A phase 1 study of PF-06840003, an oral indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor in patients with recurrent malignant glioma Reardon, David A.; Desjardins, Annick; Rixe, Olivier; Cloughesy, Timothy; Alekar, Shilpa; Williams, Jason H.; Li, Ray; Taylor, Carrie Turich; Lassman, Andrew B. 分享 收藏
Alpha-Emitters and Targeted Alpha Therapy in Oncology: from Basic Science to Clinical Investigations Makvandi, Mehran; Dupis, Edouard; Engle, Jonathan W.; Nortier, F. Meiring; Fassbender, Michael E.; Simon, Sam; Birnbaum, Eva R.; Atcher, Robert W.; John, Kevin D.; Rixe, Olivier; Norenberg, Jeffrey P. 分享 收藏
A Phase Ib Study of the Dual PI3K/mTOR Inhibitor Dactolisib (BEZ235) Combined with Everolimus in Patients with Advanced Solid Malignancies Wise-Draper, Trisha M.; Moorthy, Ganesh; Salkeni, Mohamad A.; Karim, Nagla Abdel; Thomas, Hala Elnakat; Mercer, Carol A.; Beg, M. Shalaan; O'Gara, Sue; Olowokure, Olugbenga; Fathallah, Hassana; Kozma, Sara C.; Thomas, George; Rixe, Olivier; Desai, Pankaj; Morris, John C. 分享 收藏
Phase II trial of theilndoleamine 2, 3-dioxygenase pathway (IDO) inhibitor indoximod plus immune checkpoint inhibitors for the treatment of unresectable stage 3 or 4 melanoma Zakharia, Yousef; Drabick, Joseph; Khleif, Samir; Munn, David; Link, Charles; Vahanian, Nicholas; Kennedy, Eugene; Shaheen, Montaser; Rixe, Olivier; Milhem, Mohammed 分享 收藏
High-Dose Sirolimus and Immune-Selective Pentostatin plus Cyclophosphamide Conditioning Yields Stable Mixed Chimerism and Insufficient Graft-versus-Tumor Responses Mossoba, Miriam E.; Halverson, David C.; Kurlander, Roger; Schuver, Bazetta Blacklock; Carpenter, Ashley; Hansen, Brenna; Steinberg, Seth M.; Ali, Syed Abbas; Tageja, Nishant; Hakim, Frances T.; Gea-Banacloche, Juan; Sportes, Claude; Hardy, Nancy M.; Hickstein, Dennis D.; Pavletic, Steven Z.; Khuu, Hanh; Sabatini, Marianna; Stroncek, David; Levine, Bruce L.; June, Carl H.; Mariotti, Jacopo; Rixe, Olivier; Fojo, Antonio Tito; Bishop, Michael R.; Gress, Ronald E.; Fowler, Daniel H. 分享 收藏
Effect of Renal Impairment on the Pharmacokinetics and Safety of Axitinib Chen, Ying; Rini, Brian I.; Motzer, Robert J.; Dutcher, Janice P.; Rixe, Olivier; Wilding, George; Stadler, Walter M.; Tarazi, Jamal; Garrett, May; Pithavala, Yazdi K. 分享 收藏
Results of Phase 1b trial of the Indoleamine 2,3-dioxygenase (IDO) Pathway Inhibitor Indoximod plus Ipilimumab for the treatment of unresectable stage III or IV melanoma Zakharia, Y.; Drabick, J.; Khleif, S.; Munn, D.; Link, C.; Vahanian, N.; Kennedy, E.; Rixe, O.; Milhem, M. 分享 收藏
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A DOSE ESCALATION SINGLE ARM PHASE IB COMBINATION STUDY OF BEZ235 WITH EVEROLIMUS IN PATIENTS WITH ADVANCED SOLID MALIGNANCIES Wise-Draper, T.; Moorthy, G.; Salkeni, M.; Thomas, H.; Mercer, C.; Kozma, S.; Thomas, G.; Rixe, O.; Desai, P.; Morris, J.; Olowokure, O. 分享 收藏
PHASE 1/2 STUDY OF THE COMBINATION OF INDOXIMOD AND TEMOZOLOMIDE FOR ADULT PATIENTS WITH TEMOZOLOMIDE-REFRACTORY PRIMARY MALIGNANT BRAIN TUMORS Zakharia, Yousef; Johnson, Theodore; Colman, Howard; Vahanian, Nicholas; Link, Charles; Kennedy, Eugene; Sadek, Ramses; Kong, Feng-Ming; Vender, John; Munn, David; Rixe, Olivier 分享 收藏
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A Risk-adapted Study of Cisplatin and Etoposide, with or Without Ifosfamide, in Patients with Metastatic Seminoma: Results of the GETUG S99 Multicenter Prospective Study 转移性精原细胞瘤患者顺铂和依托泊苷联合或不联合异环磷酰胺的风险适应性研究: GETUG S99多中心前瞻性研究的结果 Fizazi, Karim; Delva, Remi; Caty, Armelle; Chevreau, Christine; Kerbrat, Pierre; Rolland, Frederic; Priou, Frank; Geoffrois, Lionnel; Rixe, Olivier; Beuzeboc, Philippe; Malhaire, Jean-Pierre; Culine, Stephane; Aubelle, Marie-Stephanie; Laplanche, Agnes 分享 收藏
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