Eric A. Schon - Publications, H-index & Citations

Eric A. Schon

columbia university

94H指数

348论文数

3.7W被引数

收录论文 71

发表时间

The Mitochondrial Connection in Parkinson's Disease

Cold Spring Harbor Perspectives in Medicine

IF10.1

2026-01-01

PREAI

Schon, Eric; Matheoud, Diana; Przedborski, Serge

Aberrant ER-mitochondria communication is a common pathomechanism in mitochondrial disease

CELL DEATH & DISEASE

IF9.6

2024-06-10

OAAI

Morcillo, Patricia; Kabra, Khushbu; Velasco, Kevin; Cordero, Hector; Jennings, Sarah; Yun, Taekyung D.; Larrea, Delfina; Akman, H. Orhan; Schon, Eric A.

Towards a Unitary Hypothesis of Alzheimer's Disease Pathogenesis

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2024-04-16

OAAI

Area-Gomez, Estela; Schon, Eric A.

Mitochondrial disease: Replace or edit?

SCIENCE

IF45.8

2021-09-10

PREAI

Adashi, Eli Y.; Rubenstein, Donald S.; Mossman, Jim A.; Schon, Eric A.; Cohen, I. Glenn

MFN2 mutations in Charcot-Marie-Tooth disease alter mitochondria-associated ER membrane function but do not impair bioenergetics

HUMAN MOLECULAR GENETICS

IF3.2

2019-01-11

OAAI

Larrea, Delfina; Pera, Marta; Gonnelli, Adriano; Quintana-Cabrera, Ruben; Akman, H. Orhan; Guardia-Laguarta, Cristina; Velasco, Kevin R.; Area-Gomez, Estela; Dal Bello, Federica; De Stefani, Diego; Horvath, Rita; Shy, Michael E.; Schon, Eric A.; Giacomello, Marta

Mitochondria, OxPhos, and neurodegeneration: cells are not just running out of gas 线粒体，OxPhos和神经变性: 细胞不仅仅是耗尽气体

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2019-01-02

112

OAAI

Area-Gomez, Estela; Guardia-Laguarta, Cristina; Schon, Eric A.; Przedborski, Serge

A key role for MAM in mediating mitochondrial dysfunction in Alzheimer disease

CELL DEATH & DISEASE

IF9.6

2018-02-28

183

OAAI

Area-Gomez, Estela; de Groof, Ad; Bonilla, Eduardo; Montesinos, Jorge; Tanji, Kurenai; Boldogh, Istvan; Pon, Liza; Schon, Eric A.

SCO2 mutations cause early-onset axonal Charcot-Marie-Tooth disease associated with cellular copper deficiency

BRAIN

IF11.7

2018-01-16

OAAI

Rebelo, Adriana P.; Saade, Dimah; Pereira, Claudia V.; Farooq, Amjad; Huff, Tyler C.; Abreu, Lisa; Moraes, Carlos T.; Mnatsakanova, Diana; Mathews, Kathy; Yang, Hua; Schon, Eric A.; Zuchner, Stephan; Shy, Michael E.

Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease 线粒体相关ER膜中APP-C99的定位增加导致阿尔茨海默病的线粒体功能障碍

EMBO JOURNAL

IF8.3

2017-10-10

180

OAAI

Pera, Marta; Larrea, Delfina; Guardia-Laguarta, Cristina; Montesinos, Jorge; Velasco, Kevin R.; Agrawal, Rishi R.; Xu, Yimeng; Chan, Robin B.; Di Paolo, Gilbert; Mehler, Mark F.; Perumal, Geoffrey S.; Macaluso, Frank P.; Freyberg, Zachary Z.; Acin-Perez, Rebeca; Enriquez, Jose Antonio; Schon, Eric A.; Area-Gomez, Estela

Low-dose rapamycin extends lifespan in a mouse model of mtDNA depletion syndrome

HUMAN MOLECULAR GENETICS

IF3.2

2017-09-01

OAAI

Siegmund, Stephanie E.; Yang, Hua; Sharma, Rohit; Javors, Martin; Skinner, Owen; Mootha, Vamsi; Hirano, Michio; Schon, Eric A.

On the Pathogenesis of Alzheimer's Disease: The MAM Hypothesis

FASEB JOURNAL

IF4.2

2017-02-07

131

OAAI

Area-Gomez, Estela; Schon, Eric A.

Natural underlying mtDNA heteroplasmy as a potential source of intra-person hiPSC variability

EMBO JOURNAL

IF8.3

2016-07-19

OAAI

Perales-Clemente, Ester; Cook, Alexandra N.; Evans, Jared M.; Roellinger, Samantha; Secreto, Frank; Emmanuele, Valentina; Oglesbee, Devin; Mootha, Vamsi K.; Hirano, Michio; Schon, Eric A.; Terzic, Andre; Nelson, Timothy J.

Mitochondria-associated ER membranes and Alzheimer disease

CURRENT OPINION IN GENETICS & DEVELOPMENT

IF3.6

2016-06-01

107

OAAI

Area-Gomez, Estela; Schon, Eric A.

Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice

NATURE MEDICINE

IF50

2016-01-11

200

OAAI

Cloonan, Suzanne M.; Glass, Kimberly; Laucho-Contreras, Maria E.; Bhashyam, Abhiram R.; Cervo, Morgan; Pabon, Maria A.; Konrad, Csaba; Polverino, Francesca; Siempos, Ilias I.; Perez, Elizabeth; Mizumura, Kenji; Ghosh, Manik C.; Parameswaran, Harikrishnan; Williams, Niamh C.; Rooney, Kristen T.; Chen, Zhi-Hua; Goldklang, Monica P.; Yuan, Guo-Cheng; Moore, Stephen C.; Demeo, Dawn L.; Rouault, Tracey A.; D'Armiento, Jeanine M.; Schon, Eric A.; Manfredi, Giovanni; Quackenbush, John; Mahmood, Ashfaq; Silverman, Edwin K.; Owen, Caroline A.; Choi, Augustine M. K.

ApoE4 upregulates the activity of mitochondria-associated ER membranes

EMBO REPORTS

IF6.2

2015-11-12

134

OAAI

Tambini, Marc D.; Pera, Marta; Kanter, Ellen; Yang, Hua; Guardia-Laguarta, Cristina; Holtzman, David; Sulzer, David; Area-Gomez, Estela; Schon, Eric A.

ATP-binding cassette transporters and sterol O-acyltransferases interact at membrane microdomains to modulate sterol uptake and esterification

FASEB JOURNAL

IF4.2

2015-07-28

OAAI

Gulati, Sonia; Balderes, Dina; Kim, Christine; Guo, Zhongmin A.; Wilcox, Lisa; Area-Gomez, Estela; Snider, Jamie; Wolinski, Heimo; Stagljar, Igor; Granato, Juliana T.; Ruggles, Kelly V.; DeGiorgis, Joseph A.; Kohlwein, Sepp D.; Schon, Eric A.; Sturley, Stephen L.

A new role for -synuclein in Parkinson's disease: Alteration of ER-mitochondrial communication

MOVEMENT DISORDERS

IF7.6

2015-05-07

PREAI

Guardia-Laguarta, Cristina; Area-Gomez, Estela; Schon, Eric A.; Przedborski, Serge

Cardiac deficiency of single cytochrome oxidase assembly factor scox induces p53-dependent apoptosis in a Drosophila cardiomyopathy model

HUMAN MOLECULAR GENETICS

IF3.2

2015-03-19

OAAI

Martinez-Morentin, Leticia; Martinez, Lidia; Piloto, Sarah; Yang, Hua; Schon, Eric A.; Garesse, Rafael; Bodmer, Rolf; Ocorr, Karen; Cervera, Margarita; Arredondo, Juan J.

Mitophagy in cells with mtDNA mutations Being sick is not enough

AUTOPHAGY

IF14.3

2014-11-03

OAAI

de Vries, Rosa L. A.; Gilkerson, Robert W.; Przedborski, Serge; Schon, Eric A.

NAD+-Dependent Activation of Sirt1 Corrects the Phenotype in a Mouse Model of Mitochondrial Disease

CELL METABOLISM

IF30.9

2014-06-01

304

OAAI

Cerutti, Raffaele; Pirinen, Eija; Lamperti, Costanza; Marchet, Silvia; Sauve, Anthony A.; Li, Wei; Leoni, Valerio; Schon, Eric A.; Dantzer, Francoise; Auwerx, Johan; Viscomi, Carlo; Zeviani, Massimo

研究方向